Health-related quality of life outcomes reporting associated with FDA approvals in haematology and oncology by Bishal Gyawali, Pallawi Torka, Kristopher Attwood, Medhavi Gupta, Othman Salim Akhtar, Bhavyaa Bahl, Angel Mier-Hicks, Kayla Catalfamo

“…Proportion of included trials that reported HRQoL, latency between FDA approval and first report of HRQoL data, HRQoL outcomes, and their correlation with OS (overall survival) and PFS (progression-free survival) were analysed.Results Of the 233 trials associated with 207 FDA approvals, HRQoL was reported in 50% of trials, of which only 42% had the data reported by the time of FDA approval. There were no changes in frequency of HRQoL reporting between 2015 and 2020. …”
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Predicting species distributions in the open ocean with convolutional neural networks by Morand, Gaétan, Joly, Alexis, Rouyer, Tristan, Lorieul, Titouan, Barde, Julien

“…We trained a model to predict probabilities from the environmental conditions at any specific point in space and time, using species occurrence data from the Global Biodiversity Information Facility (GBIF) and environmental data from various sources. …”
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The stability of anisotropic compact stars influenced by dark matter under teleparallel gravity: an extended gravitational deformation approach by Sneha Pradhan, Piyali Bhar, Sanjay Mandal, P. K. Sahoo, Kazuharu Bamba

“…Further, we introduce the concept of space-time deformation caused by dark matter (DM) content in DM haloes, leading to perturbations in the metric potentials $$g_{tt}$$ g tt and $$g_{rr}$$ g rr components. …”
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Synthesis, characterization, and antibacterial activities of SnO and SnO@FeCl2 nanoparticles using Olea europaea subsp. Africana (Mill.) P.S. Green mediated green by Numan Khan, Sajjad Ali Shah, Muhammad Hubab, Sidra Tul Muntaha, Ibrar Khan, Azam Hayat, Mujaddad Ur Rehman, Tawaf Ali Shah, Jaouad Bensalah, Abdel-Rhman Z. Gaafar, Musaab Dauelbait, Mohammed Bourhia

“…By using SnO@FeCl2–NP catalyst, the data shows that in initial 20 min the degradation recorded was 10% with the increase in exposure time, and the percentage of degradation reached 86.1%.…”
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Grem1 inhibits osteogenic differentiation of MBMSCs in OVX rats through BMP/Smad1/5 signaling pathway by Shan-shan Yang, Min LinHu, Xiao-hua Hu, Si-si Jiang, Wen-yue Hu, Xiao-hong Yang

“…Techniques such as Western Blot (WB) and Real-Time Quantitative PCR (RT-qPCR) were employed to determine changes in Grem1 expression in MBMSCs of postmenopausal rats and its effect on osteogenic differentiation. …”
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Application of the weighted histogram method for calculating the thermodynamic parameters of the formation of oligodeoxyribonucleotide duplexes by I. I. Yushin, V. M. Golyshev, D. V. Pyshnyi, A. A. Lomzov

“…In this paper, the use of WHAM for computation of the energy of DNA duplex formation was systematically investigated for the first time. Our results show that a reliable calculation of the hybridization parameters of new NA derivatives is possible, including derivatives not yet synthesized. …”
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Feasibility and acceptability of a virtual learning module for navigating angry conversations in clinical encounters by Valerie Shilling, Rachel Starkings, Lesley Fallowfield

“…Participants received a £25 voucher for their time. Results Twenty students took part in the project. …”
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Molecular and serological investigation of hepatitis B virus in patients with acute undifferentiated febrile illness at Tha Song Yang hospital, Tak Province, Thailand by Narin Thippornchai, Anon Sae-Oueng, Akanitt Jittmittraphap, Wang Nguitragool, Pornsawan Leaungwutiwong

“…DNA was extracted and identified for HBV using real-time polymerase chain reaction (PCR). Positive samples were further characterized for the HBV genotype using semi-nested PCR targeting the pre-S gene. …”
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Prospective Associations of the Short Form Health Survey Vitality Scale and Changes in Body Mass Index and Obesity Status by Cathrine Lawaetz Wimmelmann, Emilie Rune Hegelund, Anna Paldam Folker, Emilie Just-Østergaard, Merete Osler, Erik Lykke Mortensen, Trine Flensborg-Madsen

“…The study indicates that vitality is of predictive value for increases in BMI over time among individuals gaining weight and may further predict the development of obesity among women. …”
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Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice by Dong Han, Jue Wang, Lulu Wen, Miao Sun, Hang Liu, Yan Gao

“…Ly6Chi monocytes were quantified in the blood and brain by flow cytometry. Real-time PCR, ELISA, and immunofluorescence were utilized to detect phenotype of proinflammatory M1 and anti-inflammatory M2 microglia/macrophage. …”
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Using Attention for Improving Defect Detection in Existing RC Bridges by Sergio Ruggieri, Angelo Cardellicchio, Andrea Nettis, Vito Reno, Giuseppina Uva

“…Consequently, an improved version of YOLO11, embedding attention mechanisms to allow the network to focus on the most relevant details in each image, was trained, tested, and validated on the provided dataset, showing an overall improvement of quantitative metrics such as precision and recall, while retaining enough computational efficiency to allow real-time implementation on constrained devices. Visual explanations achieved via the Eigen-CAM algorithm were also exploited to evaluate the reliability of the predictions. …”
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Alkaloids of narrow-leaved lupine as a factor determining alternative ways of the crop’s utilization and breeding by M. A. Vishnyakova, A. V. Kushnareva, T. V. Shelenga, G. P. Egorova

“…The genetic potential of the species can be used more efficiently. At the same time, it is rational to create highly alkaloid (bitter) varieties for green manure, while food and feed varieties should not lose their adaptive potential, in particular, resistance to pathogens, due to the elimination of alkaloids. …”
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Ventilator-Associated Pneumonia After Cardiac Arrest and Prevention Strategies: A Narrative Review by Harinivaas Shanmugavel Geetha, Yi Xiang Teo, Sharmitha Ravichandran, Amos Lal

“…<i>Conclusion</i>: The prognosis for survival after cardiac arrest is already challenging, and the outlook becomes even more daunting when complicated by VAP. The timely diagnosis of VAP and initiation of antibiotics pose considerable challenges, primarily due to the invasive nature of obtaining high-quality samples and the time required for speciation and identification of antimicrobial sensitivity. …”
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Internal Limiting Membrane Peeling versus Nonpeeling to Prevent Epiretinal Membrane Formation following Vitrectomy for Posterior Segment Open-Globe Injury by Wen-Long Wei, Zhong Lin, Ming-Na Xu, Ke-Mi Feng, Zhen-Quan Zhao

“…Student’s t-test was used to evaluate differences in continuous variables, and the chi-squared test or Fisher’s exact test was used for categorical variables. Time-to-event curves were calculated from postestimation Cox proportional hazards models. …”
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Ultrastructure of Mauthner Cells in Fish Adapted to Long-Duration Vestibular Stimulation and the Effect of Ethanol by Nadezhda R. Tiras, Georgy V. Zherdev, Dmitry A. Moshkov

“…Vestibular stimulation (training and LDS) was performed in special drums that were rotated in two planes. The training time was increased from 1 min on day 1 to 30 min on day 30. …”
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Consensus representation of multiple cell–cell graphs from gene signaling pathways for cell type annotation by Yu-An Huang, Yue-Chao Li, Zhu-Hong You, Lun Hu, Peng-Wei Hu, Lei Wang, Yuzhong Peng, Zhi-An Huang

“…Our model demonstrated exceptional robustness and accuracy across various analyses, including cross-platform, cross-time, cross-sample, and clinical dataset evaluations. …”
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Effects of Polygonatum sibiricum Polysaccharides (PSP) on Human Esophageal Squamous Cell Carcinoma (ESCC) via NF-κB Signaling Pathway by Weizheng Zhou, Jiang Hong, Ji Zhu, Xiaowei Wang

“…PSP significantly inhibited the proliferation of Eca109 cells (p<0.05) on a time- and dose-dependent manner; the apoptosis rates of Eca109 cells in experimental groups were significantly increased after 48 h of culture (p<0.05); PSP significantly reduced the migration and invasion ability of Eca109 cells (p<0.05); RT-PCR results showed that the expression of IL-10 in Eca109 cells increased significantly after treatment with PSP (p<0.05), while the expression of IL-1, IL-6, TNF-α, and TGF-β decreased significantly (p<0.05). …”
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Pig nasal and rectal microbiotas are involved in the antibody response to Glaesserella parasuis by Pau Obregon-Gutierrez, Yasser Mahmmod, Emili Barba-Vidal, Marina Sibila, Florencia Correa-Fiz, Virginia Aragón

“…The nasal and rectal microbiotas of 24 piglets were sampled in two farms before vaccination and in one unvaccinated farm (naturally exposed to the pathobiont) at similar time. Microbiota composition was inferred by V3V4 16S rRNA gene sequencing and bioinformatics analysis, and the antibody response was quantified using the variation between the levels before and after vaccination (normalized per farm). …”
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Cyanide ion oxidation by catalytic effect of nickel ferrites activated carbon composites by C. Feijoo, E. De la Torre, R. Narvaez

“…FINDINGS: Oxidation results showed that the ideal Ni/Fe molar ratio was 1/2, and the calcination time was 4 h at 600 and 900ᵒC for co-precipitation and hydro-chemical pathways of nickel ferrites, respectively. …”
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PoWBWM: Proof of work consensus cryptographic blockchain-based adaptive watermarking system for tamper detection applications by P. Aberna, L. Agilandeeswari

“…The advances in photography technology have made it possible to capture real-time high-dynamic-range (HDR) images through an iPhone or an Android device, which highlights the need for rigorous research on HDR images for tamper detection, and localization. …”
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