Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System by Fernanda C. Paccola Mesquita, Camila Hochman-Mendez, Jacquelynn Morrissey, Luiz C. Sampaio, Doris A. Taylor

“…Growing this number of cells in a traditional 2D cell culture system requires extensive time, resources, and effort and does not always meet clinical requirements. …”
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A Low-Cost IoT System Based on the ESP32 Microcontroller for Efficient Monitoring of a Pilot Anaerobic Biogas Reactor by Sotirios D. Kalamaras, Maria-Athina Tsitsimpikou, Christos A. Tzenos, Antonios A. Lithourgidis, Dimitra S. Pitsikoglou, Thomas A. Kotsopoulos

“…This IoT-enhanced system effectively demonstrated real-time monitoring of critical bioreactor parameters, with ESP32 enabling advanced control and monitoring capabilities.…”
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Submicrosecond Q-Switching Er-Doped All-Fiber Ring Laser Based on Black Phosphorus by Yao Cai, Yanliang He, Xiaoke Zhang, Rui Jiang, Chenliang Su, Ying Li

“…By taking full advantage of the ultrafast relaxation time of BP-SA and careful design of compact ring cavity, we obtained stable Q-switching pulses output with a shortest duration as narrow as 742 ns. …”
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SOX7 is involved in polyphyllin D-induced G0/G1 cell cycle arrest through down-regulation of cyclin D1 by Zheng Bin, Wang Gang, Gao Wenbo, Wu Qiquan, Zhu Weizhi, Weng Guobin

“…Moreover, PD inhibited the proliferation of PC-3 cells in a dose- and time-dependent manner. PD induced G0/G1 cell cycle arrest, while co-treatment with short interfering RNA targeting SOX7 (siSOX7) had reversed this effect. …”
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Thermal and chemical pretreatment of Ebenaeae Diospyros preusii seed for enhanced adsorptive removal of aqueous-bound Cr(VI) by H. O. Abugu, C. E. Ikwelle, O. A. Odewole, A. Lawal, A. M. Olaleye, I. A. Ucheana, J. C. Okenwa, J. C. Egbueri

“…Batch adsorption method was employed in the evaluation of the adsorbent’s adsorption performance. pH effect, initial Cr(VI) concentration, temperature and contact time influence on adsorption were also evaluated. …”
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Design, simulation, and manufacturing of analyzer optical cell for detection and measurement of injectable odorant at pressure reduction stations by Hamideh Samari Jahromi, Mohsen Abdollahi, Azardokht Mazaheri, Soleyman Mantaghi, Amirhomayoon Rezaeian, Ali Sadouni, Hamidreza Naseri, Kioumars Taheri, Fariborz Hashemipour, Foad Hamzavi, Abdolsamad Naseh

“…Installing this analyzer in PRSs enables precise adjustment of odorant injection dosages based on the analyzer's real-time results.…”
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Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MKN45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene by Khadijeh Sadegh, Amirhossein Ahmadi, Ahmad Shadi, Ahmad Ghasemi

“…The effects of HLBS on the expression of the two top-ranked GC hub genes were measured using real-time polymerase chain reaction. Comparisons between groups were performed using the ANOVA test by GraphPad Prism software at the statistically significant P-value <0.05.Results: HLBS with an IC50 concentration of 75 μg/ml at 48 hours resulted in a significant decrease in cell viability, clonogenic ability (46.63% reduction, P < 0.01), and migration of MKN45 cells (74.5% reduction, P < 0.01). …”
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Phase 1 study of novel anti-platelet agent to overcome pharmacogenomic limitations of clopidogrel by Anil Pareek, Nitin Chandurkar, Vivek Raut, Kumar Naidu

“…The pharmacokinetics and pharmacodynamics were assessed on day 1 and day 6 at several time intervals.Results Overall result of pharmacodynamic parameters showed that mean %inhibition of platelet aggregation between AT-10 and clopidogrel in all subjects at 6 hours postdose (loading dose) (AT-10: clopidogrel; 73.30% vs 18.53%) and 6 hours postdose on day 6 (maintenance dose) (AT-10: clopidogrel; 83.41% vs 51.19 %) obtained from the AT-10 group was significantly higher than the clopidogrel group. …”
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Optimizing Soft Tissue Emergence Profile Around One-Piece Dental Implants by Abduljaleel Azad Samad

“…Conclusion and Clinical implications: We concluded that using of a customized composite temporary crown fabricated by Cervico system offers a very simple and time-saving technique for the clinician, aiding in splinting the implants and obtaining nice emergence profile around one-piece implants. …”
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Retrospective Analysis of Bone Metabolism in Patients on Waiting List for Simultaneous Pancreas-Kidney Transplantation by Simona Kratochvílová, Jana Brunová, Petr Wohl, Věra Lánská, František Saudek

“…We retrospectively compiled biochemical and densitometrical data from 177 patients with T1DM at CKD (chronic kidney disease) stages G4-G5 (115 men, 62 women, median age 40 yr, diabetes duration 23 yr) enrolled on waiting list for SPK for the first time between the years 2011 and 2016. Median Z-scores were as follows: lumbar spine (LS): -0.8 [interquartile range -1.75 to 0.1]; total hip (TH): -1.2 [-1.75 to -0.6]; femoral neck (FN): -1.2 [-1.9 to -0.7]; and distal radius (DR): -0.8 [-1.4 to -0.1]. …”
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Mechanically stable polymer networks incorporating polymeric ionic liquids for enhanced conductivity in solid-state electrolytes by Sezer Özenler, Nataliya Kiriy, Upenyu L. Muza, Martin Geisler, Anton Kiriy, Brigitte Voit

“…Molecular weights of the PIL samples, ranging from 30 to 40 kDa, were determined using a complimentary combination of thermal field-flow fractionation (ThFFF) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis. …”
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Evaluating the impact of a multimodal perinatal education program on birth preparedness, mental health, and birth outcomes among rural primiparous women: a retrospective cohort stu... by Wei Li, TaiFang Ren, GuiHong Xu, YongShu Wang

“…A reduction in depressive (P = 0.021) and anxiety symptoms (P = 0.017) was also observed in the Intervention Group over time. There were significant differences in the mode of delivery and reasons for cesarean deliveries between the groups, with a higher rate of vaginal births (P = 0.035) and fewer maternal indications for cesareans (P = 0.021) in the Intervention Group compared to the Control Group. …”
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Anti-Myxovirus Resistance Protein-1 Immunoglobulin A Autoantibody in Idiopathic Pulmonary Fibrosis by Toru Arai, Masaki Hirose, Yoshimasa Hamano, Tomoko Kagawa, Akihiro Murakami, Hiroshi Kida, Atsushi Kumanogoh, Yoshikazu Inoue

“…We measured anti-MX1 immunoglobulin (Ig) G, IgA, and IgM autoantibody levels by enzyme-linked immunosorbent assay in serum collected at the time of diagnosis from 71 patients with IPF diagnosed according to the 2018 IPF guideline. …”
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Deformation and movement characteristics of debris flow landslide: A case study of the Shaziba landslide in Enshi, China by Zijian SHI, Wen CHEN, Yifan SHENG, Guangli XU

“…It is determined that the movement time of the landslide was approximately 757 seconds, with a maximum average velocity of 4.9 m/s, and an average sliding distance of about 960 m. …”
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Preliminary development and evaluation of a mechanical handwriting assistive device to support individuals with movement disorders by Gabrielle Lemire, Gabrielle Lemire, Thierry Laliberté, Katia Turcot, Katia Turcot, Véronique H. Flamand, Véronique H. Flamand, Alexandre Campeau-Lecours, Alexandre Campeau-Lecours

“…Future prospects for this study include developing an electronic version of the HAD, allowing real-time adjustable damping to better support users' voluntary movements while further stabilizing involuntary motions.…”
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The Variations of Satellite-Based Ecosystem Water Use and Carbon Use Efficiency and Their Linkages with Climate and Human Drivers in the Songnen Plain, China by Bo Li, Fang Huang, Shuai Chang, Ning Sun

“…The results showed that ecosystem WUE and CUE have fluctuated over time, with regional average values of 1.319 gC·kg−1H2O and 0.516, respectively. …”
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Decision-making behavior of blood glucose management and its influencing factors in pregnant women with gestational diabetes mellitus by Shuai Xu, Jing Wang, Yan Wang, Dawei Wang, Meng Zhang

“…The influencing factors of decision-making behavior included length of time after diagnosed with gestational diabetes mellitus, gestational diabetes mellitus history, self-efficacy, severity, susceptibility, response efficacy, and response costs (P<0.05, for all).…”
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Phenols from Vaccinium dunalianum Wight: Secondary Mass Spectrometry Fragmentation and Neuroprotective Effect by ZHOU Tang, WANG Ji, QIAO Wenhao, LIN Zhiqi, ZHU Hongbo, CHANG Yue, HU Weiyan, ZHANG Rongping, CHEN Xinglong

“…Totally 16 phenolic compounds were isolated and identified from the water extract of V. dunalianum buds, including seven arbutins, four flavonoids, two lignansand, and three other phenolic compounds, among which compounds 2–5, 7, and 11–16 were isolated from the Vaccinium genus for the first time. Secondary mass spectrometry (MS/MS) analysis revealed that the major fragmentation pathway of glycosides in the negative ion mode was the breakage of glycosidic bonds to produce fragments of aglycone or glycosyl units. …”
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A sustainable method for analyzing and studying the fractional-order panic spreading caused by the COVID-19 pandemic by Muhammad Farman, Evern Hincal, Parvaiz Ahmad Naik, Ali Hasan, Aceng Sambas, Kottakkaran Sooppy Nisar

“…In the simulation, all classes are shown to have convergent properties and to hold their positions over time, which accurately depicts how COVID-19 infection behaves in practice. …”
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Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways by Ning Liu, Jiao Feng, Xiya Lu, Zhilu Yao, Qing Liu, Yang Lv, Yuru Han, Jingfan Deng, Yingqun Zhou

“…Protein and mRNA expressions were assayed by western blotting, immunohistochemistry, and quantitative real-time polymerase chain reaction. Results. Isorhamnetin significantly inhibited liver fibrosis in both models, inhibiting hepatic stellate cell (HSC) activation, extracellular matrix (ECM) deposition, and autophagy. …”
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