The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients by Semra Özkan Öztürk, Seval Müzeyyen Ecin

“…Our analysis included assessment of several serum markers, including triglyceride, high-density lipoprotein (HDL), uric acid, low-density lipoprotein (LDL), neutrophil, lymphocyte, monocyte, white blood cell, hemoglobin and platelet levels. …”
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IgG4-Related Disease without Overexpression of IgG4: Pathogenesis Implications by Naoshi Nishina, Yuko Kaneko, Masataka Kuwana, Hironari Hanaoka, Hideto Kameda, Shuji Mikami, Tsutomu Takeuchi

“…The serum IgG4 level was normal and histopathological examination of the pituitary mass showed abundant lymphocyte and plasma cell infiltration with very few IgG4-positive cells. …”
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Hemotoxicity Induced by Chronic Chlorpyrifos Exposure in Wistar Rats: Mitigating Effect of Vitamin C by Suleiman F. Ambali, Joseph O. Ayo, King A. N. Esievo, Samuel A. Ojo

“…The elevated values of malonaldehyde, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and neutrophil/lymphocyte ratio in the CPF group were restored in those pretreated with vitamin C. …”
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Differences in the intrahepatic expression of immune checkpoint molecules on T cells and natural killer cells in chronic HBV patients by Lucile Dumolard, Marie-Noelle Hilleret, Marie-Noelle Hilleret, Charlotte Costentin, Charlotte Costentin, Marion Mercey-Ressejac, Marion Mercey-Ressejac, Nathalie Sturm, Nathalie Sturm, Theophile Gerster, Thomas Decaens, Thomas Decaens, Evelyne Jouvin-Marche, Patrice N. Marche, Zuzana Macek Jilkova, Zuzana Macek Jilkova

“…Immune checkpoint molecules (ICMs) control the amplitude of the activation and function of immune cells, which makes them the key regulators of immune response.MethodsWe performed a multiparametric flow cytometry analysis of ICMs and determined their expression on intrahepatic lymphocyte subsets in untreated and treated patients with HBV in comparison with non-pathological liver tissue.ResultsThe liver of untreated HBV patients exhibited a high accumulation of PD-1+CD8+ T cells, while the frequencies of 4-1BB+ T cells, 4-1BB+ natural killer (NK) cells, and TIM-3+CD8+ T cells were the highest in the chronic hepatitis phase. …”
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The Relationship between Inflammatory Marker Levels and Hepatitis C Virus Severity by Qitian He, Quan He, Xue Qin, Shan Li, Taijie Li, Li Xie, Yan Deng, Yu He, Yongbin Chen, Zhifu Wei

“…Red cell distribution width (RDW) and platelet-lymphocyte ratio (PLR) have been studied in a variety of etiological diseases. …”
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ATLAS-seq: a microfluidic single-cell TCR screen for antigen-reactive TCRs by Siwei Luo, Amber Notaro, Lan Lin

“…Here, we develop a microfluidic single-cell screening method for antigen-reactive T cells named ATLAS-seq (Aptamer-based T Lymphocyte Activity Screening and SEQuencing). This technology isolates and characterizes activated T cells via an aptamer-based fluorescent molecular sensor, which monitors the cytotoxic cytokine IFNγ secretion from single T cells upon antigen stimulation, followed by single-cell RNA and single-cell TCR sequencing. …”
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The Parenteral Vitamin C Improves Sepsis and Sepsis-Induced Multiple Organ Dysfunction Syndrome via Preventing Cellular Immunosuppression by Yu-Lei Gao, Bin Lu, Jian-Hua Zhai, Yan-Cun Liu, Hai-Xia Qi, Ying Yao, Yan-Fen Chai, Song-Tao Shou

“…The negative immunoregulation of Tregs was inhibited, mainly including inhibiting the expression of forkhead helix transcription factor- (Foxp-) 3, cytotoxic T lymphocyte associated antigen- (CTLA-) 4, membrane associated transforming growth factor-β (TGF-βm+), and the secretion of inhibitory cytokines [including TGF-β and interleukin- (IL-) 10], as well as CD4+ T cells-mediated cellular immunosuppression which was improved by parenteral Vit C in WT and Gulo−/− septic mice. …”
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Metastatic Invasive Lobular Breast Cancer Presenting Clinically with Esophageal Dysphagia by Lilit Karapetyan, Heather Laird-Fick, Reuben Cuison

“…Repeat EGD with biopsy showed lymphocytic esophagitis, and she was started on swallowed fluticasone. …”
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Association between Parathyroid Hormone Levels and Inflammatory Markers among US Adults by Shih-Ping Cheng, Chien-Liang Liu, Tsang-Pai Liu, Yi-Chiung Hsu, Jie-Jen Lee

“…Using data from the National Health and Nutrition Examination Survey, we examined the relation between serum PTH and C-reactive protein (CRP), red cell distribution width (RDW), and platelet-to-lymphocyte ratio (PLR) levels with weighted linear regression. …”
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Paraneoplastic Limbic Encephalitis Resembling Acute Herpetic Encephalitis by Ioannis Markakis, Athanasios Papathanasiou, Ermioni Papageorgiou, Kostantinos Siarkos, Georgios Gkekas

“…CSF analysis revealed marked lymphocytic pleocytosis. A possible diagnosis of acute herpetic encephalitis was rendered and patient was treated with acyclovir. …”
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Two Paediatric Patients with Encephalopathy and Concurrent COVID-19 Infection: Two Sides of the Same Coin? by Katerina Vraka, Dipak Ram, Siobhan West, Wei Yen Evelyn Chia, Praveen Kurup, Gayathri Subramanian, Hui Jeen Tan

“…However, the first patient was positive for serum MOG antibodies with normal CSF analysis, and the second had negative MOG antibodies but showed significant CSF lymphocytic pleocytosis. We concluded that the first case was a typical case of demyelination, which could have been triggered by different cofactors. …”
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Early Differentiation of Human CD11c+NK Cells with γδ T Cell Activation Properties Is Promoted by Dialyzable Leukocyte Extracts by Dalia Ramírez-Ramírez, Eduardo Vadillo, Lourdes Andrea Arriaga-Pizano, Héctor Mayani, Sergio Estrada-Parra, Marco Antonio Velasco-Velázquez, Sonia Mayra Pérez-Tapia, Rosana Pelayo

“…Our findings suggest that DLE increases their differentiation toward a conspicuous CD56+CD16+CD11c+ NK-like cell population endowed with properties such as IFNy production, tumor cell cytotoxicity, and the capability of inducing γδ T lymphocyte proliferation. Of note, long-term coculture controlled systems showed the bystander effect of DLE-stromal cells by providing NK progenitors with signals to overproduce this cell subset. …”
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CD4 T-Cell-Independent Antibody Response Reduces Enterovirus 71 Lethality in Mice by Decreasing Tissue Viral Loads by Li-Chiu Wang, Chia-Min Kao, Pin Ling, Ih-Jen Su, Tung-Miao Chang, Shun-Hua Chen

“…Enterovirus 71 (EV71) has induced fatal encephalitis in hundreds of thousands of infants and young children in the Asia-Pacific region since the past decade. Lymphocyte and antibody responses have been suspected to aggravate EV71-induced neurological symptoms, so anti-inflammatory agents have been used to treat patients with neurological symptoms. …”
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Peritoneal Tuberculosis in an Immunocompetent, Unknown Risk Patient by Yutaka Tomizawa, Emmanuelle B. Yecies, Fiona E. Craig, Adam Sohnen

“…Diagnostic paracentesis yielded WBC of 295/mm3, lymphocytic predominance (70%), and serum ascitic albumin gradient of 0.1, consistent with exudate. …”
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TNF-α Promotes IFN-γ-Induced CD40 Expression and Antigen Process in Myb-Transformed Hematological Cells by Wenyi Gu, Jiezhong Chen, Lei Yang, Kong-Nan Zhao

“…Tumour necrosis factor-α also increased the ability of interferon-γ to produce the mixed lymphocyte reaction to allogenic T cells. Furthermore, only cotreatment with tumour necrosis factor-α and interferon-γ induced Myb-transformed hematological cells to express interleukin-6. …”
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Monocyte Subsets, Stanford-A Acute Aortic Dissection, and Carotid Artery Stenosis: New Evidences by Noemi Cifani, Maria Proietta, Maurizio Taurino, Luigi Tritapepe, Flavia Del Porto

“…Results of this study identify in AAD patients a peculiar monocyte array that can partly explain depletion of T CD4+ lymphocyte subpopulations observed in patients affected by AAD.…”
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Imaging in connective tissue disease-associated interstitial lung disease by Praveen P G. Rao, Kushal Joshi, Sidath Liyanage, Daniel Dalili, Gouri Koduri

“…Other less common but well-recognized patterns are organizing pneumonia, lymphocytic interstitial pneumonitis, diffuse alveolar damage, and disease-modifying antirheumatic drug-related pneumonitis. …”
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Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle by A. D. Alekseev

“…The product was injected subcutaneously at a dose of 0.025 ml/kg of live weight to cows in late gestation and calves showing mild anemia, low red blood cells counts, leukocytosis, high lymphocyte and monocyte counts and elevated erythrocyte sedimentation rate, which suggest inflammatory processes in the animal body. …”
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Profiling Laboratory Biomarkers Associated with COVID-19 Disease Progression: A Single-Center Experience by Maria Khan, Noman Shah, Hina Mushtaq, Valeed Jehanzeb

“…A noteworthy increase was observed in neutrophil count (11.05 × 109/L) and a decrease was observed in lymphocyte count (0.27 × 109/L) (P<0.05), and the platelet count was borderline decreased (244.1 × 109/L). …”
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Tracking of The Most Significant Laboratory Parameters For The Identification of Covid-19: An Overview on The Different Blood Tests by Seenaa Ali

“…Laboratory data have shown that most patients had a decrease in lymphocyte count, Eosinophils count and albumin level. …”
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