Analysis of early efficacy and immune reconstitution after autologous hematopoietic stem cell transplantation in multiple myeloma by Kaili Chen, Huixin Liang, Zezhong Yu, Guangyao Guo, Huijian Zheng, Yun Huang, Liping Liu, Jie Lin, Jinlan Long, Renyao Pan, Xi Chen, Changgui Wang, Wenjie Zhang, Zhenshu Xu

“…Data on efficacy (efficacy evaluation, renal function and hemoglobin recovery), immune reconstitution (B-cell subsets, immunoglobulin levels, T-cell subsets, NK cells, neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR)) and hematopoietic reconstitution times were collected and analyzed. …”
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Associations of CTLA4 Gene Polymorphisms with Graves’ Ophthalmopathy: A Meta-Analysis by Pengfei Du, Xiaojie Ma, Changjiang Wang

“…Many studies have established that T-lymphocyte antigen-4 (CTLA4) is a susceptible gene for Graves’ disease (GD). …”
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The use of hyaluronic acid fillers in patients with autoimmune endocrinopathies; in particular, women with Hashimoto’s disease – hints for aesthetic doctors by Katarzyna Bornikowska, Paweł Kubik, Wojciech Zgliczyński

“…One of the most prevalent autoimmune diseases is chronic lymphocytic thyroiditis, so-called Hashimoto’s disease, which affects one in every 5–10 women who visit a regenerative medicine doctor. …”
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Osteogenesis Imperfecta with Celiac Disease and Type II Diabetes Mellitus Associated: Improvement with a Gluten-Free Diet by Luis Rodrigo, Isabel Pérez-Martinez

“…She suffered from recurrent abdominal pain and chronic diarrhea and was diagnosed of celiac disease (CD) with increased intraepithelial duodenal infiltration, being classified as lymphocytic enteritis, Marsh I type. She was put on a gluten-free diet (GFD), having lost 6 kg of weight after 6 months, with a good control of DM-II and presenting a significant clinical improvement. …”
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Predicting cytomegalovirus infection and graft-versus-host disease using QuantiFERON-CMV and Monitor in pediatric transplants: a proof-of-concept study by Lina Souan, Rawad Rihani, Maher A. Sughayer

“…QF-CMV and QFM were associated with CMV-Ag, with QF-CMV inversely predicting GvHD. Lymphocyte and neutrophil counts were positively linked to both tests. …”
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Natural Catalytic Antibodies in Norm, Autoimmune, Viral, and Bacterial Diseases by Georgy A. Nevinsky, Valentina N. Buneva

“…A significant increase in the relative Abz activities associated with a specific reorganization of the immune system, including changes in the differentiation and proliferation of bone marrow hematopoietic stem cells and lymphocyte proliferation in different organs. Different mechanisms of Abz production can be proposed for healthy externally immunized and for autoimmune mammals during the development of pathology.…”
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Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease by Myung Ho Rho, Dong Wook Kim

“…Histopathological examination of the 209 cases revealed normal thyroid (n=157), Hashimoto thyroiditis (n=17), non-Hashimoto lymphocytic thyroiditis (n=34), and diffuse hyperplasia (n=1). …”
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Effect of Negative Pressure Therapy on the Inflammatory Response of the Intestinal Microenvironment in a Porcine Septic Model by Kenneth C. Norbury, Mary Pat Moyer

“…The SOC group showed significant reduction in lymphocyte numbers compared to NPT group by T48 (p<0.05). …”
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Promising Neutrophil-Associated Biomarkers in Lung Diseases of Patients with Antisynthetase Syndrome and Dermatomyositis by Lei Liu, Jundi Wang, Peiyu Zhang, Wenjia Sun, Xiuliang Zhu, Xiujuan Sun, Jing Xue, Huaxiang Wu

“…Patients with ASS and DM had abnormal lymphocyte and neutrophil counts compared to healthy subjects, but not in relation to lung function and rapid progression of interstitial lung disease (RP-ILD). …”
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Vitamin D and Selenium: Review of Clinical Trials of Synergistic Effects on Thyroid Antibody Levels and Disease Progression in Hashimoto’s Thyroiditis by Agnieszka Starzyk, Piotr Charzewski

“…It is characterized by chronic lymphocytic infiltration of the thyroid gland, leading to hypothyroidism and the production of thyroid-specific autoantibodies, particularly anti-thyroid peroxidase (anti-TPO) and anti-thyroglobulin (anti-TG) antibodies. …”
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Prognostic significance of ımmunhistochemical axl expression in pancreas ductal adenocarcinomas by Ozden Oz, Asuman Argon, Tulu Ayata Kebat, Ozlem Ozdemir, Savas Yakan

“…Features of tumors; size, lymphovascular invasion (LVI), perineural invasion (PNI), resection margin (RM), lymph node metastasis (LNM), differentiation, tumor-infiltrating lymphocyte, stage and overall survival were recorded. …”
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Comparative phytochemical and pharmacological analysis of two cultivars of Annona squamosa L. cultivated in Egypt by Safaa Yassin, Samah M. Elsohafy, Amr El-Hawiet, Maged S. Abdel-Kader, Doaa A. Ghareeb, Fikria A. Darwish, Masouda E. Amer

“…In contrast, Annona B. pulp had higher carbohydrate content and lower magnesium ions content. The splenic lymphocyte proliferation assay revealed that Annona A. pulp extract was slightly more active as an immunostimulant. …”
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Urbanization enhances body condition, but not innate immune defences, in a common waterbird by Amelia Chyb, Kevin D. Matson, Radosław Włodarczyk, Joanna Drzewińska-Chańko, Piotr Minias

“…We also quantified the heterophil to lymphocyte ratio to control for the potential effect of physiological stress on immune defences. …”
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GSH/pH-responsive copper-based cascade nanocomplexes inducing immunogenic cell death through cuproptosis/ferroptosis/necroptosis in oral squamous cell carcinoma by Yi Sun, Enze Li, Wenzhao Zhong, Zhaoming Deng, Ziyao Zhou, Ka Hong Wong, Xiangwei Li

“…Additionally, the induction of ICD facilitates dendritic cell maturation and cytotoxic T lymphocyte infiltration, providing durable anti-tumor immunity. …”
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Network Medicine‐Based Strategy Identifies Maprotiline as a Repurposable Drug by Inhibiting PD‐L1 Expression via Targeting SPOP in Cancer by Saisai Tian, Mengting Xu, Xiangxin Geng, Jiansong Fang, Hanchen Xu, Xinying Xue, Hongmei Hu, Qing Zhang, Dianping Yu, Mengmeng Guo, Hongwei Zhang, Jinyuan Lu, Chengyang Guo, Qun Wang, Sanhong Liu, Weidong Zhang

“…Due to the limitations and certain side effects of current ICIs, such as programmed death protein‐1, programmed cell death‐ligand 1, and cytotoxic T lymphocyte‐associated antigen 4 (CTLA4) antibodies, there is an urgent need to find new drugs with ICP inhibitory effects. …”
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Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer by Soomin Kim, Jaemoon Koh, Tae Min Kim, Songji Oh, Soyeon Kim, Jeonghwan Youk, Miso Kim, Bhumsuk Keam, Yoon Kyung Jeon, Dong-Wan Kim, Dae Seog Heo

“…The most predominant immune subtypes before and after treatment was the interferon-γ (IFN-γ)-dominant C2 subtype and the lymphocyte-depleted C4 subtype. Two patients who showed the opposite pattern, transiting from C4 to C2, had durable responses to subsequent atezolizumab/bevacizumab/carboplatin/paclitaxel treatment. …”
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DNA Damage and Augmented Oxidative Stress in Bone Marrow Mononuclear Cells from Angiotensin-Dependent Hypertensive Mice by Bianca P. Campagnaro, Clarissa L. Tonini, Breno V. Nogueira, Dulce E. Casarini, Elisardo C. Vasquez, Silvana S. Meyrelles

“…In this study we demonstrated that 2K1C hypertensive mice have an elevated lymphocyte count, while undifferentiated BM-MNC counts were diminished. 2K1C mice also showed an augmented ROS production and marked BM-MNC DNA fragmentation. …”
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Prognostic and Risk Factors in Patients with Locally Advanced Cutaneous Squamous Cell Carcinoma of the Trunk and Extremities by de Lima Vazquez Vinicius, Cristovam Scapulatempo, Natalia Martins Perpetuo, Faheez Mohamed, Teóclito Sachetto de Carvalho, Antônio Talvane Torres de Oliveira, José Getúlio Martins Segalla, André Lopes Carvalho

“…Podoplanin was positive in 41.8% of primary tumors and 41.7% of metastases. Intratumoral lymphocytic infiltrate was associated with lymph node metastasis. …”
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Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors by Gianluigi Zaza, Paola Tomei, Paolo Ria, Simona Granata, Luigino Boschiero, Antonio Lupo

“…The main mechanism of action of these drugs is the inhibition of the mammalian target of rapamycin (mTOR), a regulatory protein kinase involved in lymphocyte proliferation. Additionally, the inhibition of the crosstalk among mTORC1, mTORC2, and PI3K confers the antineoplastic activities of these drugs. …”
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The phase I RELEASE clinical trial to evaluate the safety of NK cells in COVID-19 by Clara Hernández-Blanco, Karima Al-Akioui-Sanz, Lara Herrera, Cristina Aguirre-Portolés, Daniel Lozano-Ojalvo, Leticia Pérez-Rodriguez, Jordi Cano-Ochando, Pilar Guerra-García, Alejandro Martín-Quirós, José Luis Vicario, Silvia Santos, Miguel Ángel Pérez-Vaquero, Miguel Ángel Vesga, Alberto M. Borobia, Antonio J. Carcas, Antonio Balas, Miguel Ángel Moreno, Rebeca Pérez de Diego, Mercedes Gasior, Bernat Soria, Cristina Eguizabal, Antonio Pérez-Martínez

“…Exploratory outcomes included the donor chimerism, NK-cell immunophenotype evolution, and immune lymphocyte reconstitution. This study provides preliminary evidence supporting the idea that treatment of COVID-19 patients with moderate/severe symptoms using NK from COVID-19 convalescent donors is feasible and safe.…”
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