Hodgkin Lymphoma at the Paediatric Oncology Unit of Gabriel Touré Teaching Hospital, Bamako, Mali: 5-Year Experience by B. Togo, F. Traoré, A. P. Togo, C. B. Traoré, K. Dumke, M. Diawara, A. A. Diakité, M. Sylla, F. Traoré-Dicko, B. Traoré, T. Sidibé

“…There were 3 cases (42.8%) of sclero-nodular subtype, 2 cases (28.6%) of lymphocyte-rich classical HL subtype, 1 case (14.3%) of mixed cellularity and 1 case (14.3%) of lymphocyte depleted subtype. …”
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Age-related immune response disparities between adults and children with severe COVID-19: a case–control study in China by Hongliang Chen, Hongliang Chen, Yuan Li, Liping Yuan, Fen Liu, Qian Sun, Qian Sun, Qingkai Luo, Yefei Lei, Yinglan Hou, Jiayan Li, Liang Cai, Shixing Tang

“…A case–control study was conducted using propensity score matching (PSM) to mitigate possible confounding factors.ResultsThe significant differences observed included lymphocyte exhaustion, an increased neutrophil-to-lymphocyte (NEU/LYM) ratio, high levels of C-reactive protein (CRP), and a cytokine storm, characterized by high levels of Th1 proinflammatory cytokines, including interleukin 1β (IL-1β), IL-6, IL-8, interferon type I (IFN-γ), and tumor necrosis factor (TNF-α) in the lung among severe adult COVID-19 patients. …”
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Persistent NK cell deficiency associated with pulmonary cryptococcosis by Martin Martinot, Shu Shun Li, Catherine Farnarier, Cléa Dubrou, Christelle Piperoglou, Christopher H. Mody, Frederic Vely

“…Exhaustive immunological investigations revealed a primary NK cell deficiency associated with a secondary impaired anti-Cryptococcus CD8 lymphocyte response and the expansion of a CD8Vβ14 + T cell clone. …”
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A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer by Luis Munoz-Erazo, Luis Munoz-Erazo, Saem Mul Park, Saem Mul Park, Shelly Lin, Shelly Lin, Chun-Jen J. Chen, Chun-Jen J. Chen, Lisa Y. Y. Zhou, Lisa Y. Y. Zhou, Janet L. Rhodes, Janet L. Rhodes, Taesung Jeon, Sonya Fenton, John L. McCall, Roslyn A. Kemp, Roslyn A. Kemp, P. Rod Dunbar, P. Rod Dunbar

“…Multiplexed staining for CD20, CD3, CD8, Foxp3 and Ki-67 enabled us to identify B-cells, CD8+ T-cells, Foxp3– CD4 T-cells, and Foxp3+ CD4 Tcells in all sections, and quantify both the presence of these cell subsets in lymphocytic clusters and their degree of proliferation within those clusters.ResultsIn total we identified 524 lymphocytic clusters with morphology consistent with TLS. …”
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Herpes Simplex Virus-2 Glycoprotein Interaction with HVEM Influences Virus-Specific Recall Cellular Responses at the Mucosa by Sarah J. Kopp, Christopher S. Storti, William J. Muller

“…We investigated whether the gD-HVEM interaction during priming changes lymphocyte recall responses in the murine intravaginal model. …”
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Chronic Inflammatory Periodontal Disease in Patients with Human Immunodeficiency Virus. by Vania López Rodríguez, Emilio Carpio Muñoz, Vicente Fardales Macías, Iralys Benítez Guzmán

“…Other variables were measured, such as smoking habits, T CD4+ lymphocyte counting and virus load. The independent association of each risk factor with the disease was determined through a logistic regression model. …”
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The Relationship Between Acute Phase Reactants Levels at the Time of Admission and Comorbid Conditions with Mortality in Patients Diagnosed With Covid-19 by Öznur Köylü, Ramazan Köylü, Muhammet Ali Erinmez

“…İn deceased patients; Procalcitonin, lactate, leukocyte, neutrophil, urea, creatine, asti crpi ferritin, d-dimer values were found to be higher than the other group. Lymphocyte, lymphocyte percentage and pH values were found to be significantly low. …”
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A Novel Inflammation-Based Stage (I Stage) in Patients with Resectable Esophageal Squamous Cell Carcinoma by Peng-Cheng Chen, Ji-Feng Feng

“…The I stage was calculated as follows: patients with high levels of C-reactive protein (CRP) (>10 mg/L), neutrophil-to-lymphocyte ratio (NLR) (>3.5), and platelet-count-to-lymphocyte ratio (PLR) (>150) were defined as I3. …”
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First-Trimester Threatened Abortion: Can Red Blood Cell Distribution Width-Standard Deviation Predict Miscarriage? by Sebnem Karagun, Yusuf Dal, Hamza Yildiz, Sefanur Gamze Karaca, Ahmet Zeki Nessar, Ayhan Coskun

“…Notably, no statistically significant differences were identified in the neutrophil-lymphocyte ratio (NLR), derived NLR (DNLR), systemic inflammatory immune index (SII), platelet-to-lymphocyte ratio (PLR), and delta neutrophil index (DNI). …”
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D8/17 Monoclonal Antibody: An Unclear Neuropsychiatric Marker by Astrid Morer, Odette Viñas, Luisa Lázaro, Jordi Bosch, Josep Toro, Josefina Castro

“…Objective: It has been hypothesized that monoclonal antibody D8/17 identifies a B lymphocyte antigen with expanded expression in patients with rheumatic fever, childhood onset obsessive-compulsive disorder (OCD), Tourette syndrome (TS) or prepubertal anorexia nervosa (AN). …”
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Systemic Inflammatory Markers for Predicting Overall Survival in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis by Xiaotong Song, Hao Zhang, Fanxing Yin, Panpan Guo, Xiaocheng Yang, Jinzhu Liu, Yanshuo Han, Zhaozhou Ren

“…These inflammatory markers include C-reactive protein (CRP), neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), platelet to lymphocyte ratio (PLR), and Glasgow prognostic score (GPS). …”
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Erythropoietin supplementation induces dysbiosis of the gut microbiota and impacts mucosal immunity in a non-diseased mouse model by Guillaume Sarrabayrouse, Corentin Joulain, Stéphanie Bessoles, Andrada S. Chiron, Andrada S. Chiron, Amine M. Abina, Salima Hacein-Bey-Abina, Salima Hacein-Bey-Abina

“…With regard to the mucosal immune system, an analysis of leukocyte populations in the small intestine and colon treatment revealed low proportions of ileal CD4 lymphocyte subpopulations (Treg, Tr17 and Th17 cells), IgA-secreting plasma cells, and a major macrophage subpopulation, involved in the control of lymphocyte responses. …”
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Comparative Evaluation of Hemato-biochemical and Oxidative Parameters of Racing Horses by Jamila Abdulhamid Atata, Abdullateef Abiodun Ajadi, Muhammed Adam, Aishat Omobolanle Olatunji, Muhammed Bisalla, Sani Adamu

“…The result revealed significant changes (P < 0.05) in vital parameters such as erythrocyte count, hematocrit index, hemoglobin concentration, leucocyte count, lymphocyte, neutrophil, neutrophil: lymphocyte ratio, total protein, albumin, urea, creatinine, cortisol, lactate, lactate dehydrogenase, creatinine kinase, aspartate aminotransferase, while glucose, cholesterol, triglyceride, gamma-glutamyl transferase, malondialdehyde, glutathione peroxidase, and catalase remained unaltered (P > 0.05). …”
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Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis by Yan Lin, Yu Dong, Yanfeng Gao, Ranran Shi, Yubing Li, Xiuman Zhou, Wenwen Liu, Guodong Li, Yuanming Qi, Yahong Wu

“…In this study, we identified cytotoxic T lymphocyte epitopes on drug resistance-associated membrane protein efflux pumps of MTB, the ATP-binding cassette and the major facilitator superfamilies. …”
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Proliferation and TH1/TH2 Cytokine Production in Human Peripheral Blood Mononuclear Cells after Treatment with Cypermethrin and Mancozeb In Vitro by Rajesh Mandarapu, Rajanna Ajumeera, Vijayalakshmi Venkatesan, Balakrishna Murthy Prakhya

“…In the study here, the possible effects of cypermethrin and mancozeb on lymphocyte proliferation and proinflammatory (tumor necrosis factor (TNF-) α) and immunoregulatory cytokine (interferon- (IFN-) γ, interleukins (IL) 2, 4, 6, and 10) formation in vitro were investigated. …”
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The value of common blood parameters for the differential diagnosis of respiratory tract infections in children by Jun’e Ma, Ting Tian, Nianyi Zeng, Yue Gu, Xuewei Ren, Zhengjiang Jin

“…However, common blood tests is simple and efficient, Therefore, the purpose of this study is to preliminarily distinguish Mycoplasma pneumoniae and influenza A virus infection in children by analyzing the results of common blood tests, thereby guiding clinical diagnosis and treatment.The results showed that, compared with children in the influenza A virus-positive group, children in the Mycoplasma pneumoniae-positive group had higher white blood cell (WBC), red blood cell (RBC), haemoglobin (HGB), platelet (PLT) counts, lymphocyte (LYM) and eosinophil (EOS) counts and ratios, as well as higher concentrations of C-reactive protein (CRP) and serum amyloid A (SAA), while neutrophil (NEU) and monocyte (MONO) counts and ratios, Neutrophil to Lymphocyte ratio( NLR) were lower, in addition, LYM, EOS counts and ratios, and NLR were all more effective in differentiating between the two pathogen infections, A combined analysis of these indicators further improved the differentiation efficacy. …”
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Differential Recruitment of Dendritic Cells Subsets to Lymph Nodes Correlates with a Protective or Permissive T-Cell Response during Leishmania (Viannia) Braziliensis or Leishmania... by A. K. Carvalho, K. Carvalho, L. F. D. Passero, M. G. T. Sousa, V. L. R. da Matta, C. M. C. Gomes, C. E. P. Corbett, G. E. Kallas, F. T. Silveira, M. D. Laurenti

“…To better understand the dichotomy in the immune response caused by these Leishmania species, we evaluated subsets of dendritic cells (DCs) and T lymphocyte in draining lymph nodes during the course of La and Lb infection in BALB/c mice. …”
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Impairments of Antigen-Presenting Cells in Pulmonary Tuberculosis by Ludmila V. Sakhno, Ekaterina Ya. Shevela, Marina A. Tikhonova, Sergey D. Nikonov, Alexandr A. Ostanin, Elena R. Chernykh

“…The phenotype and functional properties of antigen-presenting cells (APC), that is, circulating monocytes and generated in vitro macrophages and dendritic cells, were investigated in the patients with pulmonary tuberculosis (TB) differing in lymphocyte reactivity to M. tuberculosis antigens (PPD-reactive versus PPD-anergic patients). …”
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The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases by Takuji Itakura, Hirokazu Sasaki, Tadashi Hosoya, Natsuka Umezawa, Tetsuya Saito, Hideyuki Iwai, Hisanori Hasegawa, Hiroyuki Sato, Akihiro Hirakawa, Kohsuke Imai, Tomohiro Morio, Naoki Kimura, Shinsuke Yasuda

“…To clarify the significance of TRECs and KRECs as immune indicators in patients with systemic autoimmune diseases, we prospectively evaluated TREC and KREC levels with qPCR, lymphocyte phenotypes with flow cytometry, along with lymphocyte counts and serum immunoglobulin levels in peripheral blood samples from newly diagnosed patients. …”
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Deep learning for predicting prognostic consensus molecular subtypes in cervical cancer from histology images by Ruoyu Wang, Gozde N. Gunesli, Vilde Eide Skingen, Kari-Anne Frikstad Valen, Heidi Lyng, Lawrence S. Young, Nasir Rajpoot

“…In addition, our extensive tumour microenvironment analysis reveals differences between the two CMS subtypes, with CMS-C1 tumours exhibit increased lymphocyte presence, while CMS-C2 tumours show high nuclear pleomorphism, elevated neutrophil-to-lymphocyte ratio, and higher malignancy, correlating with poor prognosis. …”
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