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1061
Identification of important genes related to ferroptosis in early missed abortion based on WGCNA
Published 2025-01-01“…CIBERSORT analysis revealed a notable increase in the infiltration levels of CD8 + T lymphocytes and M2 macrophages among individuals in the early missed abortion group. …”
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1062
Uptake of CCR7 by KIR2DS4+ NK Cells Is Induced upon Recognition of Certain HLA-C Alleles
Published 2015-01-01“…The KIR2DS4 receptor is the oldest KIR2DS expressed by human NK lymphocytes. The specificity of recognition of this receptor for various HLA class I alleles has been demonstrated; however it remains poorly understood whether these interactions may result in the activation of some specific functions in NK cells. …”
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1063
Immunophenotyping in BK Virus Allograft Nephropathy Distinct from Acute Rejection
Published 2013-01-01“…Immunostaining for infiltrating lymphocytes showed that the number of CD20 cells (P<0.001) and the percentages of CD3 (P<0.001), CD4 (P=0.004), CD8 (P=0.005), and CD20 (P=0.002) cells were all significantly different between BKVN and AR. …”
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1064
Crosstalk between Tumor-Infiltrating Immune Cells and Cancer-Associated Fibroblasts in Tumor Growth and Immunosuppression of Breast Cancer
Published 2021-01-01“…The immune cells including tumor-infiltrating lymphocytes (TILs) (cytotoxic T cells (CTLs), regulatory T cells (Tregs), and helper T cell (Th)), monocyte-infiltrating cells (MICs), myeloid-derived suppressor cells (MDSCs), mast cells (MCs), and natural killer cells (NKs) play an important part in the immunological balance, fluctuating TME between protumoral and antitumoral responses. …”
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1065
GENOME POLITICS: STRATEGY AND TACTICS
Published 1999-01-01“…For better realization of information in some cases the genome changes the usual way of expression, that is, the genome uses some tactical approaches: at the DNA level - restructuring of the genome (mating type in yeasts, sex determination in some flies and worms, V(D)J recombination in immunoglobulin genes in human B lymphocytes); at the RNA level - gene splicing, alternative and self splicing, RNA editing; at the protein level - protein splicing. …”
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1066
Immunosuppressive Phenotype of Esophagus Tumors Stroma
Published 2020-01-01“…Tumor-associated macrophages (TAMs) and tumor-infiltrating lymphocytes (TILs) contribute significantly to the development of immunosuppressive properties of a tumor. …”
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1067
Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone
Published 2019-01-01“…Tumor-infiltrating lymphocytes (TILs) and the expression of immune checkpoint markers were analyzed by immunohistochemistry. …”
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1068
Bone marrow immune cells and drug resistance in acute myeloid leukemia
Published 2025-02-01“…The abnormal number and function of immunosuppressive cells, including regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs), along with the dysfunction and exhaustion of immunological effector cells, including cytotoxic T lymphocytes (CTLs), dendritic cells (DCs) and natural killer cells (NKs), can induce immune escape of leukemia cells and are closely linked to therapy resistance in leukemia. …”
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1069
The morphofunctional and biochemical characteristics of opisthorchiasis-associated cholangiocarcinoma in a Syrian hamster model
Published 2015-12-01“…It was shown that the development of cholangiocarcinoma (18 weeks) increased the total number of basophils, eosinophils and monocytes, the relative number of granulocytes, the amount of total and direct bilirubin, and cholesterol and ALT levels, but reduced the relative number of lymphocytes. Based on pathological, morphometric and biochemical analyses, our model has characteristics similar to those in patients with opisthorchiasisassociated cholangiocarcinoma. …”
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1070
The immunity-promoting activity of porcine placenta in mice as an immunomodulator for functional foods
Published 2022-11-01“…Mice model experiment revealed that compared with the control, the PPH treatment significantly improved the spleen index (P < 0.05) by increasing the phagocytic rate of macrophages from 20 % to 60 % and the conversion rate of T lymphocytes from 8 % to 60 %. The qPCR analysis disclosed that the porcine placenta powder enhanced mice immunity via promoting the expression of Th1 cytokines of interleukin-2 (IL-2) and IFN-γ, especially the former, by almost 8 times in the spleens of male mice, while inhibited Th2 cytokines of IL-4 and IL-10. …”
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1071
Age effects on measurements of hypothalamic-pituitary-adrenal axis activation in laying hens
Published 2025-03-01“…The H:L ratio was not affected by treatment but heterophils increased and lymphocytes decreased in the ACTH group compared to the control group, this difference was observed at 26 WOA (P < 0.0004). …”
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1072
Evaluation of Regulatory Immune Response in Skin Lesions of Patients Affected by Nonulcerated or Atypical Cutaneous Leishmaniasis in Honduras, Central America
Published 2018-01-01“…NUCL is characterized by mononuclear inflammatory infiltration of the dermis, composed mainly of lymphocytes followed by macrophages with discrete parasitism. …”
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1073
Chronic Inflammatory Arthropathy Preceding Acute Systemic Manifestations of Sarcoidosis: A Possible Overlap of Idiopathic Juvenile Arthritis and Sarcoidosis
Published 2019-01-01“…Sarcoidosis is a multisystem disease with unknown etiology, marked by T lymphocytes and macrophages agglomeration, which leads to the formation of noncaseating granulomas in the affected tissues. …”
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1074
STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn’s Disease
Published 2019-01-01“…Innate lymphoid cells (ILCs) are tissue-resident innate effector lymphocytes which play crucial roles in mucosal immune defense, tissue repair, and maintenance of homeostasis. …”
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1075
BDNF Levels and Cognitive Function in Patients with Type 2 Diabetes Treated with SGLT2 Inhibitors
Published 2025-01-01“…Significant correlations were observed between BDNF levels and the levels of microalbumin, microalbumin/creatinine, estimated glomerular filtration rate (eGFR), lymphocytes, According to linear regression analysis, effect of eGFR levels in predicting BDNF levels was significant. …”
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1076
Effect of Oral Administration with Lactobacillus plantarum CAM6 Strain on Sows during Gestation-Lactation and the Derived Impact on Their Progeny Performance
Published 2021-01-01“…Also, the probiotic administration of sows changed (P≤0.05) the serum concentration of Na+, pCO2, and D-β-hydroxybutyrate and increased (P≤0.05) the leukocytes, lymphocytes, and platelets in their piglets. Conclusion. …”
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1077
Interleukin-2/Anti-Interleukin-2 Immune Complex Expands Regulatory T Cells and Reduces Angiotensin II-Induced Aortic Stiffening
Published 2014-01-01“…Adaptive immune function is implicated in the pathogenesis of vascular disease. Inhibition of T-lymphocyte function has been shown to reduce hypertension, target-organ damage, and vascular stiffness. …”
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1078
Histomorphological Description of the Digestive System of Pebbly Fish, Alestes baremoze (Joannis, 1835)
Published 2017-01-01“…The intestinal mucosa was thrown into villi of varying heights, with the tallest in the anterior part, lined with a simple columnar epithelium with numerous lymphocytes-like infiltrations. Numerous goblet cells appeared in the intestinal lamina epithelialis; these increased uniformly towards the anal opening. …”
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1079
Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response
Published 2015-01-01“…Finally, we have noted that IL-8 is the major chemokine responsible for recruiting T lymphocytes (CD3+, CD4+, and CD8+ T cells). In summary, our data suggest that the association of IL-8 with M. tb molecules may modify and possibly enhance the innate immune response in patients with TB.…”
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1080
Clinical Characteristics of COVID-19 Patients with and without Diabetes in Wuhan Red Cross Hospital
Published 2020-01-01“…Diabetes, higher level of D-dimer, and a lymphocyte count<0.6×109/L at admission were the risk factors associated with in-hospital death.…”
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