Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions by Massimo Ralli, Andrea Botticelli, Irene Claudia Visconti, Diletta Angeletti, Marco Fiore, Paolo Marchetti, Alessandro Lambiase, Marco de Vincentiis, Antonio Greco

“…Melanoma is one of the most immunologic malignancies based on its higher prevalence in immune-compromised patients, the evidence of brisk lymphocytic infiltrates in both primary tumors and metastases, the documented recognition of melanoma antigens by tumor-infiltrating T lymphocytes and, most important, evidence that melanoma responds to immunotherapy. …”
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Nutritional Assessment of individuals interned in a general hospital by Carla de Oliveira Barbosa Rosa, Bárbara Pereira da Silva, Karla Pereira Balbino, Sônia Machado Rocha Ribeiro, Andréia Queiroz Ribeiro, Heloísa Helena Firmino

“…The results revealed a high prevalence of anemia in the individuals (56.9%); most of them (74.6%) showed leukocytes within the normal range and lymphocytes (65.5%) below the desirable range. The anthropometric assessment identified a great many individuals as having excess of body weight (45.1%). …”
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Some haematological values in the healthy hamdani (hareki-harki) sheep by Mursayettin Eksen, Z. Tevfik Ağaoğlu, Ercan Keskin

“…On the other hand, the lymphocytes, neutrophils, monocytes and eosin ophils were determined as 53.6 %, 39.0 %, 4.6 % and 2.8 % in the female sheep, whereas these values found to be 49.2%, 44.0%, 4.4% and 2.4% in male sheep respectively.…”
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Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer by Riley J. Morrow, Nima Etemadi, Belinda Yeo, Matthias Ernst

“…The role of the tumor microenvironment, through tumor-associated macrophages, infiltrating lymphocytes, and cancer stem cells is also discussed, suggesting that these tumor extrinsic factors may help account for the differences in behavior between inflammatory breast cancer and noninflammatory breast cancer. …”
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Increased Chromosomal and Oxidative DNA Damage in Patients with Multinodular Goiter and Their Association with Cancer by Hamiyet Donmez-Altuntas, Fahri Bayram, Nazmiye Bitgen, Sibel Ata, Zuhal Hamurcu, Gulden Baskol

“…CBMN-cyt assay parameters in peripheral blood lymphocytes of patients with multinodular goiter and controls were evaluated, and plasma 8-OHdG levels were measured. …”
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Differential pathological changes in colon microenvironments in acute and chronic mouse models of inflammatory bowel disease by NaYeon Ham, Minji Park, Young-An Bae, Eui-Ju Yeo, YunJae Jung

“…In contrast, the chronic phase was characterized by tissue remodeling, with a significant increase in M2 macrophages and lymphocytes. RNA-sequencing revealed genetic changes in acute and chronic colitis, marked by the maintenance of genomic integrity in the acute phase and extracellular matrix dynamics in the chronic phase. …”
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Persistence of Brucella abortus in the Bone Marrow of Infected Mice by Cristina Gutiérrez-Jiménez, Lisiena Hysenaj, Alejandro Alfaro-Alarcón, Ricardo Mora-Cartín, Vilma Arce-Gorvel, Edgardo Moreno, Jean Pierre Gorvel, Elías Barquero-Calvo

“…This persistence was associated with histopathological changes, accompanied by augmented numbers of BM myeloid GMP progenitors, PMNs, and CD4+ lymphocytes during the acute phase (eight days) of the infection in the BM. …”
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Immunotherapy for Hepatocellular Carcinoma: Current Advances and Future Expectations by Yingjun Xie, Yien Xiang, Jiyao Sheng, Dan Zhang, Xiaoxiao Yao, Yongsheng Yang, Xuewen Zhang

“…Adoptive cell therapy functions by stimulating and cultivating autologous lymphocytes ex vivo and then reinfusing them into the patient to kill cancer cells. …”
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Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform by Pengyu Gao, Dan Zou, Ansha Zhao, Ping Yang

“…This review specifically covers (a) the properties of red blood cells, monocytes, macrophages, neutrophils, natural killer cells, T lymphocytes, and mesenchymal stem cells; (b) the loading strategies to balance cargo amounts and cell function balance; (c) the cascade strategies to improve cell-driven targeting delivery efficiency; and (d) the features and applications of cell membranes, artificial cells, and extracellular vesicles in cancer treatment.…”
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The Use of Fluorescence In situ Hybridisation in the Diagnosis of Hidden Mosaicism in Egyptian Patients with Turner Syndrome by Heba Mohamed Ossama, Soha Kholeif, Ghada Mohamed Elhady

“…The diagnosis of TS is based on karyotyping of 30 blood lymphocytes. This technique does not rule out tissue mosaicism or low-grade mosaicism in the blood. …”
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Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection by Muhammad Khurram, Muhammad Faheem, Muhammad Umar, Asif Yasin, Wajeeha Qayyum, Amna Ashraf, Javeria Zahid Khan, Ali Hasnain Yasir, Yusra Ansari, Muhammad Asad, Iram Khan, Shuja Abbas, Irum Rasheed, Natasha Rasool, Hamama Tul Bushra Khar

“…Dysfunction of cytotoxic T and natural killer (NK) cells causes uncontrolled activity of lymphocytes and histiocytes which leads to HLH. Infections, malignancies, and autoimmune disorders are associated with development of HLH. …”
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Elevated Proportions of Circulating CXCR5+ Follicular Helper T Cells Reflect the Presence of Airway Obstruction in Asthma by Tsukie Kin Tsukuda, Kimiko Tsuji, Akari Nishimori, Takehiko Ito, Yuka Kobayashi, Taro Suzuki, Akihito Yokoyama

“…Using flow cytometry, we identified and quantified Group 2 innate lymphocytes, T helper 2 cells, follicular helper T cells, and T helper 17 cells in peripheral blood samples from 49 individuals with asthma. …”
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Suppression of Th17 Cell Response in the Alleviation of Dextran Sulfate Sodium-Induced Colitis by Ganoderma lucidum Polysaccharides by Bing Wei, Ran Zhang, Jingbo Zhai, Junfeng Zhu, Fangli Yang, Dan Yue, Xiaoyi Liu, Changlong Lu, Xun Sun

“…GLP markedly suppressed the secretions of TNF-α, IL-1β, IL-6, IL-17A, and IL-4 and significantly affected populations of Th17 cells, B cells, NK cells, and NKT cells in the lamina propria lymphocytes. Conclusions. GLP prevented inflammation, maintained intestinal homeostasis, and regulated the intestinal immunological barrier functions in mice with DSS-induced colitis.…”
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Esophageal submucosal gland duct adenoma: a case report and literature review by Bing Zhou, Jian Zheng, Ling Huang, Hua Hao

“…On microscopic examination, the submucosal tumor was found to be composed of glandular cavities of various sizes, bland cytology with infrequent mitotic figures, and the interstitium was infiltrated by a large number of lymphocytes. Immunohistochemical analysis revealed the expression of adenomyoepithelial cytokeratins (CK) CK7, CK5/6, and p63. …”
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Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma by Girolamo Pelaia, Alessandro Vatrella, Maria Teresa Busceti, Luca Gallelli, Cecilia Calabrese, Rosa Terracciano, Rosario Maselli

“…These immune-inflammatory profiles develop as a consequence of a functional impairment of T regulatory (Treg) lymphocytes, which promotes the activation of dendritic cells directing the differentiation of distinct Th cell subsets. …”
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Structure and Function of the LRBA Protein by Ege Ezen, Mehmet Cihangir Çatak, Feyza Bayram Çatak, Sofia Piepoli, Pegah Zahedimaram, Ecem Ultanır, Safa Barış, Batu Erman

“…LRBA was shown to be responsible for the re-shuttling of the T-cell co-inhibitory receptor CTLA4 back to the plasma membrane after internalization and lack or mutation of LRBA results in surface deficiency of CTLA4 in regulatory and activated T lymphocytes. The large molecular size of these proteins indicates that they may have pleiotropic functions in the immune system and beyond. …”
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Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia by Amal F. Alshammary, Ghada BinSaif, Imran Ali Khan

“…In vitiligo, cytotoxic T-lymphocytes damage melanocytes, causing skin depigmentation. …”
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Therapeutic anti-inflammatory immune potentials of some seaweeds extracts on chemically induced liver injury in mice by Eman Bases, Mostafa M. El-Sheekh, Shimaa M. El Shafay, Rania El-shenody, Mohamed Nassef

“…Pre-treatment and post-treatment of P. pavonia and J. rubens extracts in CCL4/mice increased WBCs count and lymphocytes relative numbers and reduced the neutrophils and monocytes relative numbers. …”
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Serum levels of soluble IL-2R, CD4 and CD8 in bronChial asthma by G. Di Lorenzo, P. Mansueto, M. Melluso, G. Morici, F. Norrito, D. Cigna, G. Candore, C. Caruso

“…The aim of the present study was to compare serum levels of soluble forms of interleukin-2 receptor, CD4 and CD8, released by lymphocytes during activation of the immune system, in patients with allergic bronchial asthma, with those in healthy subjects. …”
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Maternal Hypertension and Early Atherosclerotic Lesions in Aortas of Deceased Fetuses and Neonates by Janet María Capote-Santa Cruz Pacheco, Carmen Teresa Peraza Méndez, Marlene Ferrer Arrocha, Lisandra Álvarez de la Nuez, Belkis Ortega de la Campa, Mirian Castro Ortega

“…<br /><strong>Results:</strong> of the total number of deceased studied, 70.6 % presented early atherosclerotic lesions, characterized by thickening of the intima as a cushion, presence of lymphocytes in the intima or in the arterial wall close to it and/or macrophages. …”
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