The Pathology of T Cells in Systemic Lupus Erythematosus by Anselm Mak, Nien Yee Kow

“…Compelling evidence has however shown that without the assistance of the helper T lymphocytes, it is indeed difficult for the “helpless” B cells to become functional enough to trigger SLE-related inflammation. …”
Get full text

Response of host immune system to tick borne encephalitis virus by Iveta Stibraniova, Pavlina Bartikova, Jozef Dzubara

“…In turn, cell-mediated immunity provided by T and B lymphocytes plays an important role in virus clearance and protective immunity, and thus influences the outcome of disease. …”
Get full text

The importance of multiple Z- plasty- assisted physical therapy in the treatment of Dupuytren’s contracture by Nader Gomaa Elmelegy, Dalia Nader

“…Results Histologically, all our specimens showed chronic inflammatory skin lesions showing hyperkeratotic epidermal covering and dermal infiltration with aggregates of chronic inflammatory cells, mainly lymphocytes and plasma cells, proliferated vascular spaces, and fibrous stroma. …”
Get full text

Reactive Lymphoid Hyperplasia of the Liver Incidentally Found in a 55-Year-Old Woman with a History of Ulcerative Colitis by Noritoshi Mizuta, Takuya Kikuchi, Shunsuke Kusano, Nobuya Sano

“…Histopathological findings revealed a conglomerate hyperplasia of lymphoid follicles with germinal centers. Infiltrating lymphocytes were non-neoplastic. Final diagnosis was RLH of the liver. …”
Get full text

A Rare Presentation of Pancreatic Lymphoepithelial Cyst: A Case Report and Review by Grace E. Kim, Fariha Ramay, Stephanie Richards, Peter E. Darwin

“…CT scan showed an increased mass in the pancreatic head, and endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) revealed “rare fragments of benign-appearing squamous epithelium in a background of keratin debris, cyst contents, and scattered lymphocytes,” consistent with a lymphoepithelial cyst. …”
Get full text

Pneumocystis carinii: A Review of an Important Opportunistic Pathogen in AIDS by M John Gill, Ron Read

“…Animal studies and clinical observations show that a significant depletion or dysfunction of T helper lymphocytes predisposes to clinical disease. Individuals with damaged T helper cells secondary to malignancies (eg, Hodgkin’s lymphoma), drugs (eg, cyclosporine, steroids), or certain infections (eg, human immunodeficiency virus) are at particular risk. …”
Get full text

Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms by Hideaki Watanabe

“…Published data has demonstrated that among patients with DIHS/DRESS, 75–95% have leukocytosis, 18.2–90% show atypical lymphocytes, 52–95% have eosinophilia, and 75–100% have hepatic abnormalities. …”
Get full text

Immune Dysfunction in Tourette Syndrome by Ishraga Elamin, Mark J. Edwards, Davide Martino

“…A similar link has been proposed also for Tourette syndrome (TS), a complex, multifactorial disorder, in which the interplay between genetic, environmental, hormonal and immunological factors might be relevant. Lymphocyte subpopulation analysis in TS suggests a possible systemic activation of several T- and B-cell subtypes, whereas the observed decreased numbers of T regulatory lymphocytes might predispose to autoimmunity. …”
Get full text

T Cell/Histiocyte-Rich Large B Cell Lymphoma of the Thymus: A Diagnostic Pitfall by Jie Xu, Xiaojun Wu, Vishnu Reddy

“…The excised lymph nodes were replaced by diffuse infiltrate of small CD3+ lymphocytes and histiocytes with intermingled large CD20+ B lymphoma cells scattered throughout the section. …”
Get full text

Novel research model for in vitro immunotherapy: co-culturing tumor organoids with peripheral blood mononuclear cells by Peng Li, Minli Huang, Yifan Ma, Yongbin Zhang, Changhong Shi

“…This model stands as a robust instrument for dissecting the TME, elucidating the molecular interactions, and exploring the therapeutic applications of chimeric antigen receptor (CAR)-engineered lymphocytes, as well as other cancer treatment modalities. …”
Get full text

Three-Dimensional in Vivo Imaging of Green Fluorescent Protein-Expressing T Cells in Mice with Noncontact Fluorescence Molecular Tomography by Anikitos Garofalakis, Giannis Zacharakis, Heiko Meyer, Eleftherios N. Economou, Clio Mamalaki, Joseph Papamatheakis, Dimitris Kioussis, Vasilis Ntziachristos, Jorge Ripoll

“…In this study, the system was applied to determining the distribution of green fluorescent protein (GFP)-expressing T lymphocytes in a transgenic mouse model, thus demonstrating the potential of the system for studying immune system function. …”
Get full text

Mechanisms of Bone Resorption in Periodontitis by Stefan A. Hienz, Sweta Paliwal, Saso Ivanovski

“…In summary, Th1-type T lymphocytes, B cell macrophages, and neutrophils promote bone loss through upregulated production of proinflammatory mediators and activation of the RANK-L expression pathways.…”
Get full text

An Elderly Lady with Fever of Unknown Etiology and Severe Pulmonary Hypertension: Intravascular Lymphoma—An Elusive Diagnosis by Nupur Sinha, Luis Lantigua, Masooma Niazi, Gilda Diaz-Fuentes

“…Intravascular lymphoma is a rare type of diffuse large B cell lymphoma, characterized by selective intravascular growth of malignant lymphocytes, aggressive behavior, and often a fatal course. …”
Get full text

Modulatory action of Bryonia alba on the immune system in cyclophosphamide induced immunosuppression in BALB/c mice. by Vara Prasad Saka, Godlaveti Vijay Narasimha Kumar, Abanti Goswami, Bharat Kumar Reddy Sanapalli, Pankaj Gupta, Digvijay Verma, Subhash Kaushik

“…The treatment with BA maintained the spleen in a preserved state, with the white and red pulp remaining intact and a higher density of lymphocytes. The results indicate that BA could serve as a valued immunostimulant agent when administered with chemo-therapy. …”
Get full text

A Case of Hemophagocytic Syndrome due to Tuberculosis: Uncommon Manifestation of a Common Disease by Arijit Singha, Adreesh Mukherjee, Riddhi Dasgupta, Tapas Das

“…It is associated with ineffective but exaggerated immune response and infiltration of active lymphocytes and histiocytes in various organs. This devastating clinical condition has myriad of clinical and biochemical manifestations such as fever, splenomegaly, pancytopenia, hypertrygliceridemia, and hyperferritinemia. …”
Get full text

Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies by Elisa Ferretti, Vito Pistoia, Anna Corcione

“…It is constitutively expressed in many hematopoietic and nonhematopoietic tissues such as endothelial and epithelial cells, lymphocytes, neurons, microglial osteoblasts. The biological activities of CX3CL1 are mediated by CX3CR1, that is expressed on different cell types such as NK cells, CD14+ monocytes, cytotoxic effector T cells, B cells, neurons, microglia, smooth muscle cells, and tumor cells. …”
Get full text

A comparative study on the some haematological parameters of sakız, karayaka and crossbred of sakız x karayaka ci sheep by Şevket Arıkan, Arzu Yiğit, Halil Akçapınar, Nurgül Zengin, Umut Taşdemir

“…Blood samples obtained from the animals were analysed for erythrocyte (RBC) and leucocyte (WBC) numbers, haemoglobin concentrations (Hb). haematocnt values (PCV), sedimentation rates and percentages ot lymphocytes, neutrophyls, monocytes, eosinophyls and ba-sophyls. …”
Get full text

Major Histocompatibility Complex Genes as Therapeutic Opportunity for Immune Cold Molecular Cancer Subtypes by Paweł Karpiński, Łukasz Łaczmański, Maria M. Sąsiadek

“…Consequently, our study underlines the urgent need for designing strategies to enhance tumor MHC expression that could improve immune cold tumor rejection by cytotoxic T lymphocytes.…”
Get full text

Eumisetoma pada Toraks dan Abdomen: Suatu Kasus Jarang by Jimy Fran, Istiana Fiatiningsih, Ilhami Romus

“…Histopathological examination of hematoxylin-eosin showed suppurative granulomatous inflammation consisting of epitheloid histiocytes, solid lymphocytes and neutrophils, and datia cells. PAS (Periodic acid-Schiff) staining showed positive results. …”
Get full text

The Molecular Imaging of Natural Killer Cells by Mariya Shapovalova, Sean R. Pyper MD, PhD, Branden S. Moriarity PhD, Aaron M. LeBeau PhD

“…Natural killer cells are cytotoxic lymphocytes that mediate the direct killing of transformed cells with reduced or absent major histocompatibility complex (MHC) and are the effector cells in antibody-dependent cell-mediated cytotoxicity. …”
Get full text