A Full GMP Process to Select and Amplify Epitope-Specific T Lymphocytes for Adoptive Immunotherapy of Metastatic Melanoma by N. Labarriere, A. Fortun, A. Bellec, A. Khammari, B. Dreno, S. Saïagh, F. Lang

“…A number of trials of adoptive transfer of tumor-specific T lymphocytes have been performed in the last 20 years in metastatic melanoma, with increasingly encouraging results as the relevant melanoma antigens were identified and the purity/specificity of injected T cells improved. …”
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Baseline (derived) neutrophil-lymphocyte ratio associated with survival in gastroesophageal junction or gastric cancer treated with ICIs by Chengyang Yu, Hao Jiang, Liezhi Wang, Zufu Jiang, Chong Jin

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The Effects of Aloe vera Cream on the Expression of CD4+ and CD8+ Lymphocytes in Skin Wound Healing by Yos Adi Prakoso, Kurniasih

“…The result showed that topical application of 1% and 2% Aloe vera cream significantly reduced the percentage of the wound, leucocytes infiltration, angiogenesis, and expression of CD8+ lymphocytes and increased the epidermal thickness and the expression of CD4+ lymphocytes (p ≤ 0,05). …”
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Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis by Jiaona Xu, Yinan Yu, Shijie Li, Fanghui Qiu

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Evaluation of Genotoxic and Cytotoxic Effects in Human Peripheral Blood Lymphocytes Exposed In Vitro to Neonicotinoid Insecticides News by María Elena Calderón-Segura, Sandra Gómez-Arroyo, Rafael Villalobos-Pietrini, Carmen Martínez-Valenzuela, Yolanda Carbajal-López, María del Carmen Calderón-Ezquerro, Josefina Cortés-Eslava, Rocío García-Martínez, Diana Flores-Ramírez, María Isabel Rodríguez-Romero, Patricia Méndez-Pérez, Enrique Bañuelos-Ruíz

“…In the present study, human peripheral blood lymphocytes (PBL) were exposed in vitro to different concentrations of the four insecticides. …”
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Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis by Annie Elong Ngono, Maud Lepetit, Markus Reindl, Alexandra Garcia, Flora Guillot, Athénaïs Genty, Mélanie Chesneau, Marion Salou, Laure Michel, Fabienne Lefrere, Kathrin Schanda, Berthe-Marie Imbert-Marcille, Nicolas Degauque, Arnaud Nicot, Sophie Brouard, David-Axel Laplaud, Jean-Paul Soulillou

“…Although there is no evidence for a role of anti-MOG antibodies in adult MS, no information on B lymphocytes with MOG-committed BCR is available. We report here on the frequency of anti-MOG B cells forming rosettes with polystyrene beads (BBR) covalently bound to the extracellular domain of rhMOG in 38 relapsing-remitting patients (RRMS) and 50 healthy individuals (HI). …”
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Tonsil Stromal-Cell Lines Expressing FDC-Like Properties: Isolation, Characterization, and Interaction with B Lymphocytes by Grzegorz Skibinski, Anna Skibinska, Martine Deckers, Keith James

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t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature by Katherine A. Minson, Pinki Prasad, Susan Vear, Scott Borinstein, Richard Ho, Jennifer Domm, Haydar Frangoul

“…Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. …”
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Classifying tumour infiltrating lymphocytes in oral squamous cell carcinoma histopathology using joint learning framework by Barun Barua, Genevieve Chyrmang, Kangkana Bora, Gazi N. Ahmed, Lopamudra Kakoti, Manob Jyoti Saikia

“…Tumour-infiltrating lymphocytes (TILs) are recognized as a key prognostic indicator and play a vital role in OSCC grading. …”
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Hypercalcemia in Small Lymphocytic Lymphoma with an Elevated Parathyroid Hormone-Related Peptide Associated with Early Richter Transformation by Ashish Bains, Pedro Covas, Olga Timofeeva, Michael Bromberg

“…We report a case of small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) associated with hypercalcemia and an elevation in parathyroid hormone-related peptide (PTHrP) in the setting of a Richter transformation. …”
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Evaluation of Association of Oral Bacterial Profile with HBV and HCV Infection and T Lymphocyte Level in HIV-Positive Patients by Fatemeh Lavaee, Farzan Modarresi, Samira Amookhteh, Mohammad Amin Amiri

“…This study was aimed to determine the oral bacterial profile of HIV-positive patients and their correlation with T lymphocyte and CD4 count and hepatitis B and C incidence. …”
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Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture by Tim Ammon, Julia Zeiträg, Vanessa Mayr, Manuela Benedicic, Hans‐Peter Holthoff, Martin Ungerer

“…We have established novel assays to assess immune cell subpopulations, including citrullinated antigen–specific (CAS) autoreactive B and T lymphocytes, in patients with RA. Methods and Results We found that activated CD25+ T cells were markedly increased in patients with RA compared to healthy controls. …”
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Pneumocystis jirovecii Pneumonia in Patients with Nephrotic Syndrome: Application of Lymphocyte Subset Analysis in Predicting Clinical Outcomes by Yang Liu, Ke Zheng, Yecheng Liu, Huadong Zhu

“…The cut-off value of 71 cells/μl for the CD4+ T lymphocyte count was determined to identify patients with poor prognosis. …”
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The Imbalance of B-Lymphocyte Subsets in Subjects with Different Glucose Tolerance: Relationship with Metabolic Parameter and Disease Status by Chao Deng, Yufei Xiang, Tingting Tan, Zhihui Ren, Chuqing Cao, Bingwen Liu, Gan Huang, Xiangbing Wang, Zhiguang Zhou

“…B lymphocytes are involved in inflammation and are related to insulin resistance in obesity and type 2 diabetes (T2D). …”
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Salidroside Attenuates Concanavalin A-Induced Hepatitis via Modulating Cytokines Secretion and Lymphocyte Migration in Mice by Baoji Hu, Yun Zou, Shanshan Liu, Jun Wang, Jiali Zhu, Jinbao Li, Lulong Bo, Xiaoming Deng

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Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring by Federico Sizzano, Sebastiano Collino, Ornella Cominetti, Daniela Monti, Paolo Garagnani, Rita Ostan, Chiara Pirazzini, Maria Giulia Bacalini, Daniela Mari, Giuseppe Passarino, Claudio Franceschi, Alessio Palini

“…Here, the response of the main lymphocyte subsets to the induced oxidative stress in semisupercentenarians (CENT), their offspring (OFF), elderly controls (CTRL), and young individuals (YO) was analyzed using flow cytometry. …”
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Prognostic value of tumor‐infiltrating lymphocytes and PD‐L1 expression in esophageal squamous cell carcinoma by Jie Hu, Takeshi Toyozumi, Kentaro Murakami, Satoshi Endo, Yasunori Matsumoto, Ryota Otsuka, Tadashi Shiraishi, Shinichiro Iida, Hiroki Morishita, Tenshi Makiyama, Yuri Nishioka, Masaya Uesato, Koichi Hayano, Akira Nakano, Hisahiro Matsubara

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Increased dicentric chromosome in peripheral lymphocytes is related to acute skin toxicity induced by radiotherapy in cancer patients by Minjie Li, Yu Gao, Lin Han, Ping Wang, Jie Li, Junhua Song, Shasha Du, Yunfei Zhang, Yumin Lyu

“…Objective: To investigate the impacts of radiotherapy (RT) on dicentric chromosomes in peripheral blood lymphocytes of cancer patients, in order to explore the relationship between dicentric chromosomes and RT-induced adverse reactions. …”
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Reduced irradiation exposure areas enhanced anti-tumor effect by inducing DNA damage and preserving lymphocytes by Huiqin Chen, Yuan Li, Qiaofeng Shen, Guanqun Guo, Zhigang Wang, Hanyu Pan, Min Wu, Xueqing Yan, Gen Yang

“…Further investigations revealed that the enhanced efficacy of RTRT may be attributed to the preservation of lymphocytes within the peritumoral tissue, as well as reduced damage to the surrounding skin and circulating lymphocytes. …”
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A division-dependent compartmental model for computing cell numbers in CFSE-based lymphocyte proliferation assays by H. Thomas Banks, W. Clayton Thompson, Cristina Peligero, Sandra Giest, Jordi Argilaguet, Andreas Meyerhans

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