Association of neutrophil-to-lymphocyte ratio with severe abdominal aortic calcification: new evidence from the United States by Hao Deng, Mengmeng Sun, Zhentong Zhao, Kun Fan, Zizhang Zhao, Yifan Chi, Wei Sheng

“…Given the pivotal role of inflammatory mediators in the pathogenesis of aortic calcification, inflammation has attracted interest as a peripheral biomarker for early mortality prediction in patients with aortic calcification. The neutrophil-to-lymphocyte ratio (NLR) measured in the peripheral blood typically reflects the body's inflammatory response by combining laboratory markers of innate and adaptive immunity. …”
Get full text

A Full GMP Process to Select and Amplify Epitope-Specific T Lymphocytes for Adoptive Immunotherapy of Metastatic Melanoma by N. Labarriere, A. Fortun, A. Bellec, A. Khammari, B. Dreno, S. Saïagh, F. Lang

“…A number of trials of adoptive transfer of tumor-specific T lymphocytes have been performed in the last 20 years in metastatic melanoma, with increasingly encouraging results as the relevant melanoma antigens were identified and the purity/specificity of injected T cells improved. …”
Get full text

Baseline (derived) neutrophil-lymphocyte ratio associated with survival in gastroesophageal junction or gastric cancer treated with ICIs by Chengyang Yu, Hao Jiang, Liezhi Wang, Zufu Jiang, Chong Jin

Subjects: Get full text

The Effects of Aloe vera Cream on the Expression of CD4+ and CD8+ Lymphocytes in Skin Wound Healing by Yos Adi Prakoso, Kurniasih

“…The result showed that topical application of 1% and 2% Aloe vera cream significantly reduced the percentage of the wound, leucocytes infiltration, angiogenesis, and expression of CD8+ lymphocytes and increased the epidermal thickness and the expression of CD4+ lymphocytes (p ≤ 0,05). …”
Get full text

Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis by Jiaona Xu, Yinan Yu, Shijie Li, Fanghui Qiu

Get full text

Evaluation of Genotoxic and Cytotoxic Effects in Human Peripheral Blood Lymphocytes Exposed In Vitro to Neonicotinoid Insecticides News by María Elena Calderón-Segura, Sandra Gómez-Arroyo, Rafael Villalobos-Pietrini, Carmen Martínez-Valenzuela, Yolanda Carbajal-López, María del Carmen Calderón-Ezquerro, Josefina Cortés-Eslava, Rocío García-Martínez, Diana Flores-Ramírez, María Isabel Rodríguez-Romero, Patricia Méndez-Pérez, Enrique Bañuelos-Ruíz

“…In the present study, human peripheral blood lymphocytes (PBL) were exposed in vitro to different concentrations of the four insecticides. …”
Get full text

Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis by Annie Elong Ngono, Maud Lepetit, Markus Reindl, Alexandra Garcia, Flora Guillot, Athénaïs Genty, Mélanie Chesneau, Marion Salou, Laure Michel, Fabienne Lefrere, Kathrin Schanda, Berthe-Marie Imbert-Marcille, Nicolas Degauque, Arnaud Nicot, Sophie Brouard, David-Axel Laplaud, Jean-Paul Soulillou

“…Although there is no evidence for a role of anti-MOG antibodies in adult MS, no information on B lymphocytes with MOG-committed BCR is available. We report here on the frequency of anti-MOG B cells forming rosettes with polystyrene beads (BBR) covalently bound to the extracellular domain of rhMOG in 38 relapsing-remitting patients (RRMS) and 50 healthy individuals (HI). …”
Get full text

Tonsil Stromal-Cell Lines Expressing FDC-Like Properties: Isolation, Characterization, and Interaction with B Lymphocytes by Grzegorz Skibinski, Anna Skibinska, Martine Deckers, Keith James

Subjects: Get full text

t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature by Katherine A. Minson, Pinki Prasad, Susan Vear, Scott Borinstein, Richard Ho, Jennifer Domm, Haydar Frangoul

“…Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. …”
Get full text

Classifying tumour infiltrating lymphocytes in oral squamous cell carcinoma histopathology using joint learning framework by Barun Barua, Genevieve Chyrmang, Kangkana Bora, Gazi N. Ahmed, Lopamudra Kakoti, Manob Jyoti Saikia

“…Tumour-infiltrating lymphocytes (TILs) are recognized as a key prognostic indicator and play a vital role in OSCC grading. …”
Get full text

Hypercalcemia in Small Lymphocytic Lymphoma with an Elevated Parathyroid Hormone-Related Peptide Associated with Early Richter Transformation by Ashish Bains, Pedro Covas, Olga Timofeeva, Michael Bromberg

“…We report a case of small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) associated with hypercalcemia and an elevation in parathyroid hormone-related peptide (PTHrP) in the setting of a Richter transformation. …”
Get full text

Evaluation of Association of Oral Bacterial Profile with HBV and HCV Infection and T Lymphocyte Level in HIV-Positive Patients by Fatemeh Lavaee, Farzan Modarresi, Samira Amookhteh, Mohammad Amin Amiri

“…This study was aimed to determine the oral bacterial profile of HIV-positive patients and their correlation with T lymphocyte and CD4 count and hepatitis B and C incidence. …”
Get full text

Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture by Tim Ammon, Julia Zeiträg, Vanessa Mayr, Manuela Benedicic, Hans‐Peter Holthoff, Martin Ungerer

“…We have established novel assays to assess immune cell subpopulations, including citrullinated antigen–specific (CAS) autoreactive B and T lymphocytes, in patients with RA. Methods and Results We found that activated CD25+ T cells were markedly increased in patients with RA compared to healthy controls. …”
Get full text

Pneumocystis jirovecii Pneumonia in Patients with Nephrotic Syndrome: Application of Lymphocyte Subset Analysis in Predicting Clinical Outcomes by Yang Liu, Ke Zheng, Yecheng Liu, Huadong Zhu

“…The cut-off value of 71 cells/μl for the CD4+ T lymphocyte count was determined to identify patients with poor prognosis. …”
Get full text

The Imbalance of B-Lymphocyte Subsets in Subjects with Different Glucose Tolerance: Relationship with Metabolic Parameter and Disease Status by Chao Deng, Yufei Xiang, Tingting Tan, Zhihui Ren, Chuqing Cao, Bingwen Liu, Gan Huang, Xiangbing Wang, Zhiguang Zhou

“…B lymphocytes are involved in inflammation and are related to insulin resistance in obesity and type 2 diabetes (T2D). …”
Get full text

Salidroside Attenuates Concanavalin A-Induced Hepatitis via Modulating Cytokines Secretion and Lymphocyte Migration in Mice by Baoji Hu, Yun Zou, Shanshan Liu, Jun Wang, Jiali Zhu, Jinbao Li, Lulong Bo, Xiaoming Deng

Get full text

Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring by Federico Sizzano, Sebastiano Collino, Ornella Cominetti, Daniela Monti, Paolo Garagnani, Rita Ostan, Chiara Pirazzini, Maria Giulia Bacalini, Daniela Mari, Giuseppe Passarino, Claudio Franceschi, Alessio Palini

“…Here, the response of the main lymphocyte subsets to the induced oxidative stress in semisupercentenarians (CENT), their offspring (OFF), elderly controls (CTRL), and young individuals (YO) was analyzed using flow cytometry. …”
Get full text

Prognostic value of tumor‐infiltrating lymphocytes and PD‐L1 expression in esophageal squamous cell carcinoma by Jie Hu, Takeshi Toyozumi, Kentaro Murakami, Satoshi Endo, Yasunori Matsumoto, Ryota Otsuka, Tadashi Shiraishi, Shinichiro Iida, Hiroki Morishita, Tenshi Makiyama, Yuri Nishioka, Masaya Uesato, Koichi Hayano, Akira Nakano, Hisahiro Matsubara

Subjects: Get full text

Increased dicentric chromosome in peripheral lymphocytes is related to acute skin toxicity induced by radiotherapy in cancer patients by Minjie Li, Yu Gao, Lin Han, Ping Wang, Jie Li, Junhua Song, Shasha Du, Yunfei Zhang, Yumin Lyu

“…Objective: To investigate the impacts of radiotherapy (RT) on dicentric chromosomes in peripheral blood lymphocytes of cancer patients, in order to explore the relationship between dicentric chromosomes and RT-induced adverse reactions. …”
Get full text

A division-dependent compartmental model for computing cell numbers in CFSE-based lymphocyte proliferation assays by H. Thomas Banks, W. Clayton Thompson, Cristina Peligero, Sandra Giest, Jordi Argilaguet, Andreas Meyerhans

Get full text