Synaptic modulation of glutamate in striatum of the YAC128 mouse model of Huntington disease by Judy Cheng, Ellen T. Koch, Daniel Ramandi, James P. Mackay, Timothy P. O’Leary, William Rees-Jones, Lynn A. Raymond

“…D2 receptors are also expressed on glutamatergic cortical terminals, cholinergic interneurons, and dopaminergic terminals from substantia nigra where they suppress release of glutamate, acetylcholine and dopamine, respectively, and these cell types may contribute to early striatal dysfunction in HD. …”
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GluN2D-containing NMDA receptors in parvalbumin neurons in the nucleus accumbens regulate nocifensive responses in neuropathic pain by Sukanya G. Gakare, Gajanan P. Shelkar, Dinesh Y. Gawande, Ratnamala Pavuluri, Pauravi J. Gandhi, Shashank M. Dravid

“…Using conditional KO strategy, we addressed the region- and cell-type involved in GluN2D-mediated changes in CINP. …”
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Management of childbearing with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders: A scoping review and expert co-creation of evidence-based clinical guidelin... by Sally Pezaro, Isabelle Brock, Maggie Buckley, Sarahann Callaway, Serwet Demirdas, Alan Hakim, Cheryl Harris, Carole High Gross, Megan Karanfil, Isabelle Le Ray, Laura McGillis, Bonnie Nasar, Melissa Russo, Lorna Ryan, Natalie Blagowidow

“…A multidisciplinary approach is advised to address frequently seen issues in this population such as tissue fragility, joint hypermobility, and pain, as well as common comorbidities, including dysautonomia and mast cell diseases.…”
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Recombinant Production of Bovine α_S1-Casein in Genome-Reduced <i>Bacillus subtilis</i> Strain IIG-Bs-20-5-1 by Lennart Biermann, Lea Rahel Tadele, Elvio Henrique Benatto Perino, Reed Nicholson, Lars Lilge, Rudolf Hausmann

“…Upscaling in a fed-batch bioreactor system for high cell-density fermentation processes allowed for efficient recombinant α_S1-casein production. …”
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Serum IL-18 Is a Potential Biomarker for Predicting Severe Dengue Disease Progression by Josephine Diony Nanda, Chiau-Jing Jung, Rahmat Dani Satria, Ming-Kai Jhan, Ting-Jing Shen, Po-Chun Tseng, Yung-Ting Wang, Tzong-Shiann Ho, Chiou-Feng Lin

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A multigene phylogeny toward a new phylogenetic classification of Leotiomycetes by Peter R. Johnston, Luis Quijada, Christopher A. Smith, Hans-Otto Baral, Tsuyoshi Hosoya, Christiane Baschien, Kadri Pärtel, Wen-Ying Zhuang, Danny Haelewaters, Duckchul Park, Steffen Carl, Francesc López-Giráldez, Zheng Wang, Jeffrey P. Townsend

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Environmental microbial communications in gram-positive and gram-negative bacteria by P. Srikanth, D. Sivakumar, J. Nouri

“…Specific receptors found on the surface of the bacterial cell are required for the identification of pheromones or autoinducers. …”
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The Effect of Lithium on Inflammation-Associated Genes in Lipopolysaccharide-Activated Raw 264.7 Macrophages by Raymond T. Makola, Vusi G. Mbazima, Matlou P. Mokgotho, Vincent S. Gallicchio, Thabe M. Matsebatlela

“…Raw 264.7 macrophages were treated with up to 10 mM lithium, and no change in cell proliferation, viability, growth, and cell adhesion was observed in real time. …”
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Neurocognitive function and health-related quality of life among glioblastoma patients: A prospective study by Mohamed A Baba, Ahmed Kharbach, Mohamed Lmejjati, Nawal Adali

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Cryopreserved human alternatively activated macrophages promote resolution of acetaminophen-induced liver injury in mouse by Maria Elena Candela, Melisande Addison, Rhona Aird, Tak-Yung Man, Jennifer A. Cartwright, Candice Ashmore-Harris, Alastair M. Kilpatrick, Philip J. Starkey Lewis, Anna Drape, Mark Barnett, Donna Mitchell, Colin McLean, Neil McGowan, Marc Turner, James W. Dear, Stuart J. Forbes

“…In a mouse model of APAP-induced injury, peripherally injected cryopreserved hAAMs reduced liver necrosis, modulated inflammatory responses, and enhanced liver regeneration. hAAMs were effective even when administered after the therapeutic window for NAC. This cell therapy approach represents a potential treatment for APAP overdose when NAC is ineffective because liver injury is established.…”
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The effect of silymarin on ischemia-reperfusion injury in skeletal muscles of rats by Abdullah Ozer, Basak Kocak, Mustafa Arslan, Baris Mardin, Aysegul Kucuk, Saban Cem Sezen, Mustafa Hakan Zor, Mustafa Kavutcu

“…Results: In the histopathological examination, no degeneration was observed in the muscle fibers in the Group C, while findings of striated muscle damage such as muscle atrophy/hypertrophy, muscle degeneration/congestion, internalization of the muscle nucleus/oval/central nucleus, fragmentation/hyalinization and leukocyte cell infiltration were seen in the Group I/R. In Group S-I/R, muscle atrophy /hypertrophy, internalization of the muscle nucleus/oval/central nucleus, fragmentation/hyalinization, and leukocyte cell infiltration were observed to improve these damaged areas compared to Group I/R. …”
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Undernutrition disrupts jejunal and ileal microbiota and epithelial tissue homeostasis in a pregnant sheep model by Weibin Wu, Muhammad Faheem Akhtar, Jiahong Geng, Huizhen Lu, Muhammad Ajwad Rahim, Jianbo Cheng, Xiaoling Ding, Shengyong Mao, Yanfeng Xue

“…In the jejunal epithelium, genes associated with extracellular matrix–receptor interactions, cell growth, and immune response were down-regulated (P < 0.05) upon undernutrition. …”
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THE DANUBE DELTA BIOSPHERE RESERVE. GEOGRAPHY, BIODIVERSITY, PROTECTION, MANAGEMENT by PETRE GÂŞTESCU

“…Par sa position géographique, à 45º lat. nord et 29º long. est, le Delta du Danube synthétise dans lepaysage les traits des deltas des zones tempérées, étant utilisé par de nombreuses espèces d’oiseaux pour nicher, passer l’hiver ou pour transiter dans leur migration périodique des zones tropicales vers celles polaires du Nord. Grâce à ces particularités, le Delta du Danube se constitue en une région géographique qui exige une attention particulière pour son maintien dans les conditions les plus proches de celles naturelles et pour la protection des espèces d’oiseaux, certains en état de disparition. …”
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Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction by Veronica Marcos, Zhe Zhou-Suckow, Ali Önder Yildirim, Alexander Bohla, Andreas Hector, Ljubomir Vitkov, Wolf Dietrich Krautgartner, Walter Stoiber, Matthias Griese, Oliver Eickelberg, Marcus A. Mall, Dominik Hartl

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A bacterial membrane-disrupting protein stimulates animal metamorphosis by Kyle E. Malter, Tiffany L. Dunbar, Carl Westin, Emily Darin, Josefa Rivera Alfaro, Nicholas J. Shikuma

“…MACs can also deliver Mif1 to human cell lines and cause parallel phenotypes, including cell surface binding, membrane disruption, calcium flux, and mitogen-activated protein kinase activation. …”
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Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis by Shasha Huang, Shumin He, Fei Xiao, Yang Zhou, Su Lyu

“…The high expression of hsa_circ_0064338 (circ_PPARG) was confirmed in both the myocardial cell inflammation model and peripheral blood from a large sample of FM patients. …”
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Pulmonary and systemic immune alterations in rats exposed to airborne lunar dust by Brian E. Crucian, Heather Quiriarte, Chiu-wing Lam, Mayra Nelman, Audrie A. Colorado, Douglass M. Diak, John T. James

“…Although the percentage of lymphocytes increased, the T-cell CD4:CD8 ratio was unchanged. Cytokine analysis of the lavage fluid showed increased levels of IL-1β and TNFα. …”
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Efficacy of Endoscopic Radiofrequency Ablation for Treatment of Reflux Hypersensitivity: A Study Based on Rome IV Criteria by Yuan-Xi Jiang, Zhi-Yu Dong, Jun-Wen Wang, Ying Chen, Hui-Hui Sun, Shu-Chang Xu

“…After treatment, the positive cell density of both TRPV1 and CGRP decreased significantly; however, only TRPV1 had a positive correlation with heartburn (r=0.51, P=0.03) and chest pain (r=0.77, P<0.01). …”
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Nuclear Intron Sequence Variation of the <i>Bulinus globosus</i> Complex (Mollusca: Planorbidae): Implications for Molecular Systematic Analyses by Chairat Tantrawatpan, Kotchaphon Vaisusuk, Chrysantus M. Tanga, Warayutt Pilap, Naruemon Bunchom, Ross H. Andrews, Tongjit Thanchomnang, Wanchai Maleewong, Weerachai Saijuntha

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Phytochemicals of Vitis vinifera L. var. King Ruby protect mice from benzo(a)pyrene-induced lung injury by Gehad S. Ahmedy, Hend M. Selim, Mona El-Aasr, Souzan M. Ibrahim, Suzy A. El-Sherbeni

“…The sulforhodamine B (SRB) assay of the different fractions against A-549 cell line revealed that the methylene chloride fraction (MCF) had the lowest cell viability at 300 µg/mL (4.54 ± 0.19%). …”
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