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30141
Study on the protective effect of mitochonic acid-5 on septic acute kidney injury and the underlying mechanism
Published 2025-01-01“…方法细胞实验:将肾小管细胞分为正常组、MA-5(10 µmol/L)组、LPS(10 mg/L)刺激组和LPS+MA-5治疗组,通过细胞计数试剂盒8法评估细胞活力、流式细胞术评估细胞凋亡率;活性氧(reactive oxygen species,ROS)检测试剂盒检测ROS含量;三磷酸腺苷(adenosine triphosphate,ATP)检测试剂盒检测ATP水平;蛋白质印迹法(western blot,Wb)检测沉默信息调节因子3(silence information regulator 3,SIRT3)蛋白、线粒体动力学相关蛋白[动力相关蛋白1(dynamin-related protein 1,DRP1)、视神经萎缩因子1(optic atrophy 1,OPA1)]和细胞凋亡相关蛋白[B细胞淋巴瘤2(B-cell lymphoma-2,Bcl-2)、Bcl-2相关X蛋白(Bcl-2 associated X protein,Bax)]的表达水平。…”
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30142
Voltaire et Contant d’Orville: le 'Voltaire portatif' (1766), une lettre inconnue, un remerciement à l’auteur, et une réplique voilée à l’archevêque d’Auch
Published 2024-11-01“…Dans des lettres comme celle à Contant d’Orville, il a ainsi transformé une obligation routinière en une arme philosophique sophistiquée.…”
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30143
Angiogenesis Regulated by Electroacupuncture Combined with Rehabilitation Training in Cerebral Ischemia Involved in PI3K/Akt Signaling Pathway
Published 2020-10-01“…The relative expression levels of vascular endothelial growth factor (VEGF), brain-derived neurotrophic factor (BDNF), PI3K and Akt were detected by Western blot and RT-PCR respectively.Results:(1) The neurons in the ischemic area of the model group were irregular in morphology, vacuolation, reduction of glycosomes and autophagic vesicles in the cytoplasm, swelling of mitochondria and pyknosis of nucleus; Compared with the model group, on day 3, 7 and 14 of treatment, the neuron cell membrane of the combined acupuncture group showed a tendency to repair, and the structure of organelles and the degree of vacuolation were significantly improved.(2) On day 3, 7 and 14 of treatment, the MVD count of cerebral ischemia area was statistically significant in different groups (<italic>F</italic><sub>Intergroup</sub>=141.762, <italic>P</italic>< 0.001), the MVD count of the combined acupuncture group was higher than that of the other two groups, the difference was statistically significant respectively (<italic>P</italic>< 0.01); On day 3, 7 and 14 of treatment, there was significant difference in the change trend of different time points respectively (<italic>F</italic><sub>Time</sub>=81.920, <italic>P</italic>< 0.001), the combined acupuncture group increased significantly on the 14th day of treatment, and the differences were statistically significant (<italic>P</italic>< 0.01); MVD count had group×time obvious interaction (<italic>F</italic><sub>Interaction</sub>=44.960, <italic>P</italic>< 0.001). (3) The variance analysis of repeated measurements of VEGF, BDNF, PI3K, Akt proteins in the brain tissue of the ischemic area showed that the variables were statistically significant among different groups respectively (<italic>F</italic><sub>Intergroup</sub>=398.772, 903.082, 2 312.264, and 1 581.880, <italic>P</italic>< 0.001). …”
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30144
El santo, el trabajo y el amo, en tres obras de Lope sobre san Isidro
Published 2010-06-01“…Dans l’ensemble de ces trois pièces, le terrain sur lequel se situent ces épisodes légendaires a conduit le dramaturge à définir clairement sur scène la tâche qui est celle du laboureur et la position dans l’échelle sociale qui en découle, ainsi qu’à poser, à travers ces épisodes, la question de la valeur comparée de la contemplation et de l’action. …”
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30145
Theoretical Organization of Motivations to Attend First Aid Education: Scoping Review
Published 2020-06-01“…Les motivations à participer à une formation aux premiers secours ne sont pas bien documentées dans la littérature existante quant à leur ampleur ou à leur généralisation. Celles que nous avons identifiées s'inscrivent dans le cadre de théories comportementales telles qu'elles sont appliquées dans les modèles socio-écologiques et trans-théoriques qui s’adressent aux formateurs individuels et aux organismes de formation. …”
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30146
Effects of Conditioning Temperature on Pellet Quality, Nutrients Digestibility, and Metabolizable Energy of Broilers Diet
Published 2024-12-01“…Moderate thermal processing of broiler diets causes the separation of protein matrix, starch and fat, gelatinization of starch, destruction of anti-nutritional sensitive to heat and destruction of cell walls, and are considered positive chemical and physical changes in the process of pelleting with steam heat. …”
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30147
Plasma IL-17A is increased in patients with critical MIS-C and associated to in-hospital mortality
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30148
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30149
Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2<small.letters>dmepda</small.letters>H<mml:math> <mml:mrow>...
Published 2006-01-01“…The dimethyl sulphoxide(DMSO) soluble complexes (<bold>1</bold>)–(<bold>4</bold>) and (<bold>6</bold>) were assessed for their cancer chemotherapeutic potential towards hepatocellular carcinoma and kidney adenocarcinoma cell lines. The 1,10-phenanthroline containing complex [Cu(2dmepda)(phen)<mml:math> <mml:mrow> <mml:msub> <mml:mrow> <mml:mrow><mml:mrow> <mml:mrow><mml:mo>(</mml:mo> <mml:mrow><mml:msub> <mml:mtext>H</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> <mml:mtext>O</mml:mtext> </mml:mrow> <mml:mo>)</mml:mo></mml:mrow> </mml:mrow> <mml:mo>]</mml:mo></mml:mrow> </mml:mrow> <mml:mn>2</mml:mn> </mml:msub> </mml:mrow> </mml:math>0.5phen (<bold>3</bold>) was the most potent with activity that compares well to that of <emph>cis</emph>platin.…”
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30150
Pressure Methods for Primary Hemorrhage Control: A Randomized Crossover Trial
Published 2019-02-01“…Cette étude démontre que la compression manuelle directe génère une plus forte compression que celle avec un pansement. Les formateurs au premiers secours doivent appliquer ces résultats à leurs cours en décrivant l’épaisseur du matériel, et ont besoin d’appliquer suffisamment de pression pour stopper l’hémorragie. …”
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30151
Detección temprana del cáncer colorrectal, una necesidad impostergable
Published 2012-05-01“…--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>EN-US</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:DontVertAlignCellWithSp /> <w:DontBreakConstrainedForcedTables /> <w:DontVertAlignInTxbx /> <w:Word11KerningPairs /> <w:CachedColBalance /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val=" " /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><!…”
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30152
Afectividad y memoria subjetiva en pacientes con epilepsia del lóbulo temporal medial intratable
Published 2014-12-01“…--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves/> <w:TrackFormatting/> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning/> <w:ValidateAgainstSchemas/> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF/> <w:LidThemeOther>ES-TRAD</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables/> <w:SnapToGridInCell/> <w:WrapTextWithPunct/> <w:UseAsianBreakRules/> <w:DontGrowAutofit/> <w:SplitPgBreakAndParaMark/> <w:DontVertAlignCellWithSp/> <w:DontBreakConstrainedForcedTables/> <w:DontVertAlignInTxbx/> <w:Word11KerningPairs/> <w:CachedColBalance/> </w:Compatibility> <m:mathPr> <m:mathFont m:val="Cambria Math"/> <m:brkBin m:val="before"/> <m:brkBinSub m:val="--"/> <m:smallFrac m:val="off"/> <m:dispDef/> <m:lMargin m:val="0"/> <m:rMargin m:val="0"/> <m:defJc m:val="centerGroup"/> <m:wrapIndent m:val="1440"/> <m:intLim m:val="subSup"/> <m:naryLim m:val="undOvr"/> </m:mathPr></w:WordDocument> </xml><!…”
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30153
Helicobacter pylori: ¿lo tratamos de acuerdo a las evidencias?
Published 2012-06-01“…--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>EN-US</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:DontVertAlignCellWithSp /> <w:DontBreakConstrainedForcedTables /> <w:DontVertAlignInTxbx /> <w:Word11KerningPairs /> <w:CachedColBalance /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val=" " /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><!…”
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30154
Biochemical Evolution and Histological Response of Patients with Hepatitis C Undergoing Antiviral Therapy.
Published 2011-07-01“…--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>EN-US</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:DontVertAlignCellWithSp /> <w:DontBreakConstrainedForcedTables /> <w:DontVertAlignInTxbx /> <w:Word11KerningPairs /> <w:CachedColBalance /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val=" " /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><!…”
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30155
Dependencia de la gasolina. Presentación de un caso.
Published 2011-10-01“…--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:DontVertAlignCellWithSp /> <w:DontBreakConstrainedForcedTables /> <w:DontVertAlignInTxbx /> <w:Word11KerningPairs /> <w:CachedColBalance /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val=" " /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><!…”
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30156
Diplomado para docentes de Ciencias de la Salud: Validación por criterio de expertos.
Published 2011-07-01“…--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:DontVertAlignCellWithSp /> <w:DontBreakConstrainedForcedTables /> <w:DontVertAlignInTxbx /> <w:Word11KerningPairs /> <w:CachedColBalance /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val=" " /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><!…”
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30157
Decolonization Projects
Published 2023-09-01“…The burden of service for faculty of color to achieve diversity and inclusion: the minority tax. Mol Biol Cell, 31, 2752-2754. [18] Olufemi Taiwo 2020. Being-in-the-Room Privilege: Elite Capture and Epistemic Deference. …”
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30158
Multi-cancer early detection tests for general population screening: a systematic literature review
Published 2025-01-01“…Blood-based multi-cancer early detection (MCED) tests aim to detect potential cancer signals (such as circulating cell-free deoxyribonucleic acid) from multiple cancers in the blood. …”
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30159
COVID- 19 en Guaos ∶ a propósito de un caso
Published 2020-11-01“…--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves/> <w:TrackFormatting/> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning/> <w:ValidateAgainstSchemas/> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF/> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables/> <w:SnapToGridInCell/> <w:WrapTextWithPunct/> <w:UseAsianBreakRules/> <w:DontGrowAutofit/> <w:SplitPgBreakAndParaMark/> <w:EnableOpenTypeKerning/> <w:DontFlipMirrorIndents/> <w:OverrideTableStyleHps/> </w:Compatibility> <m:mathPr> <m:mathFont m:val="Cambria Math"/> <m:brkBin m:val="before"/> <m:brkBinSub m:val="--"/> <m:smallFrac m:val="off"/> <m:dispDef/> <m:lMargin m:val="0"/> <m:rMargin m:val="0"/> <m:defJc m:val="centerGroup"/> <m:wrapIndent m:val="1440"/> <m:intLim m:val="subSup"/> <m:naryLim m:val="undOvr"/> </m:mathPr></w:WordDocument> </xml><!…”
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30160