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30121
Exploration of rituximab treatment strategies for membranous nephropathy adapted to the Chinese healthcare environment
Published 2025-01-01“…Older age and higher white blood cell counts may lead to a higher relapse rate. Conclusion This study revealed that RTX treatment has a high remission rate and a low relapse rate in MN patients. …”
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30122
'Giustizia fatta': observations sur un registre des condamnés à mort (1471–1764) de la bibliothèque de Beccaria
Published 2024-11-01“…Ces pages funèbres, et celles d’autres registres semblables conservés à la Bibliothèque Ambrosienne de Milan, ont assurément stimulé par leur violence l’humanisme d’un Beccaria, l’indignation d’un Verri, la haute exigence morale d’un Manzoni, trois auteurs qui, dans leurs textes respectifs, ont fait voler en éclat la sublimation de la peine de mort comme accomplissement de la justice humaine. …”
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30123
Descriptions anatomiques et hypothèses étiologiques des déformations des mains et des pieds observées chez les chimpanzés de Sebitoli (Parc national de Kibale, Ouganda)
Published 2015-03-01“…L’objectif de notre étude est de représenter ces déformations des membres afin de distinguer les anomalies d’origine humaine (pièges, pollution environnementale…) de celles issues d’un contexte naturel (agressions lors de conflits, chute accidentelle, arthrose…). …”
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30124
Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflamma...
Published 2025-01-01“…This investigation sought to elucidate XXD’s impact on various aspects of AD pathology, including blood-brain barrier (BBB) impairment, neuroinflammatory processes, and amyloid-β (Aβ) deposition, as well as the molecular pathways involved in these effects.MethodsIn vitro experiments were conducted using hCMEC/D3 and HBVP cell coculture to establish an in vitro blood-brain barrier (BBB) model. …”
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30125
Meta-analysis: p16INK4α (Cyclin Dependent Kinase Inhibitor 2A) is one of the major causes of nasopharyngeal cancer
Published 2024-04-01“…The p16INK4α gene, also known as cyclin-dependent kinase inhibitor, is a tumor suppressor gene that inhibits Cyclin-Dependent Kinase (CDK), leading to the inhibition of CDK interaction with cyclin, thereby inhibiting the phosphorylation process on pRb, halting the cell cycle. The p16INK4α gene is located on the short arm of chromosome 9 at position 9p21.3, consisting of three exons encoding 156 amino acids (Coppé et al., 2011). …”
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30126
Les Immatériaux de Lyotard (1985) : un programme figural
Published 2009-03-01“…L’exposition se déployait sur l’ensemble du dernier étage du Centre et était conçue pour rendre sensible, et déjà du fait du parcours, une idée spéculative, celle des Immatériaux. Lyotard souhaitait un parcours en rollers. …”
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30127
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30128
Comparative Study of the Chemical Composition Disparities Between Fast-twitch and Slow-twitch Muscles in Marine Teleost Fishes
Published 2025-02-01“…Conversely, fast-twitch muscles, responsible for burst swimming, require more PUFA to maintain the structural integrity and functionality of cell membranes. The main fatty acid composition types of SFA, PUFA, and MUFA in the fast-twitch and slow-twitch muscles are the same. …”
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30129
Study of hereditary non-syndromic ophthalmic pathology of child population of the Karachay-Cherkess Republic: features and structure of nosological spectrum
Published 2019-04-01“…Kutsev — MD, PhD, Professor, Сorresponding Member of RAS, Head of the Research Centre of Medical Genetics, Head of the Department of Molecular and Cell Genetics; <br> <sup>1,3</sup>Rena A. Zinchenko — MD, PhD, Professor, Deputy Director of the Scientific and Clinical Study, Head of the Laboratory of Genetic Epidemiology.…”
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30130
Études comportementales pour la conservation du singe laineux de Poeppig (Lagothrix l. poeppigii)
Published 2016-01-01“…Cette étude aura pour objectif d’appréhender la question de l’entraide chez le singe laineux et d’alimenter le débat sur la présence d’empathie chez les petits singes, en opposition à celle souvent décrite chez les grands singes. Nous espérons des retombées bénéfiques des résultats de ces trois études à deux niveaux. …”
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30131
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30132
Construction of a prognostic model for gastric cancer based on immune infiltration and microenvironment, and exploration of MEF2C gene function
Published 2025-01-01“…Based on CIBERSORT deconvolution analysis, there was difference of immune cell composition found between high and low ICI Score groups, probably affecting the efficacy of immunotherapy. …”
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30133
El Ekhtiyar ou la mise en martyr des policiers égyptiens. La construction d’un « grand récit » sur petit écran ?
Published 2023-12-01“…Pourtant, malgré cette méfiance collective envers l’institution policière, celle-ci se retrouve depuis 2013 au cœur d’une entreprise de légitimation sans précédent. …”
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30134
Hesperidin enhances broiler growth performance by augmenting gastric acid secretion via the proton pump pathway
Published 2025-02-01“…Incorporation of hesperidin into the broilers' diet significantly enhances parietal cell numbers (P < 0.05). Dietary supplementation of hesperidin in broilers effectively up-regulates key signaling pathways and intracellular signal substances involved in proton pump activation (P < 0.05). …”
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30135
Stratégies de manipulation d’outils lors de la tâche du labyrinthe chez les gorilles et les orangs-outans
Published 2016-01-01“…Une ACP a été réalisée sur l’ensemble des sessions ainsi qu’une ACP sur la session considérée comme la plus performante pour chaque individu, c’est-à-dire celle au cours de laquelle l’individu a effectué le moins de mouvements de la main. …”
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30136
Differentiation of high risk prostate cancer with a facile urinary exosome detection workflow
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30137
Neuroprotective Effect of Crocin on Rats with Focal Cerebral Ischemia-Reperfusion Injury Based on TLR4/NF-κB Pathway
Published 2022-12-01“….); western blot was used to detect the expression of toll-like receptor 4 (TLR4), nuclear factor-κB p65 (NF-κB p65), p-NF-κB p65, IκBα, p-IκBα, Cleved Caspase-3, B-lymphoma-2 gene (Bcl-2), Bcl-2-related X protein (Bax).Results(1) Neurological function, cerebral infarction rate and cerebral water content: compared with the sham operation group, the mNSS score, cerebral infarction rate, cerebral water content in the model group increased significantly (<italic>P</italic><0.05); compared with the model group, the mNSS score, cerebral infarction rate, cerebral water content in the crocin group and the crocin + lipopolysaccharide group decreased significantly (<italic>P</italic><0.05); compared with the crocin group, the mNSS score, cerebral infarction rate, cerebral water content in the crocin + lipopolysaccharide group increased significantly (<italic>P</italic><0.05). (2) Pathological changes and apoptosis of cortical neurons: the cortical neurons in the sham operation group showed normal morphology and complete structure; the pathological changes of cortical neurons such as disordered arrangement, decreased number, vacuolar degeneration, hyperchromatic cytoplasmic pyknosis, unclear nuclear membrane boundary, inflammatory cell infiltration were observed in the model group; the pathological changes of cortical neurons in the crocin group were significantly improved. …”
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30138
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30139
Genome-wide linkage mapping of Fusarium crown rot in common wheat (Triticum aestivum L.)
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30140