Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural c... by Louis-Emmanuel Chriqui, Etienne Abdelnour-Berchtold, Edoardo Zanfrini, Severine Devesa-Perez, Michel Gonzalez, Thorsten Krueger, Kim Ellefsen, Alice Destaillats, David Bonnet, Martin Hübner, Hasna Bouchaab, Michal Bassani-Sternberg, Solange Peters, Sabrina Cavin, Jean Y Perentes

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Reconnaissance des indices attentionnels humains par le babouin olive (Papio anubis) by Marie Bourjade, Adrien Meguerditchian, Florence Gaunet

“…Toutefois, la reconnaissance des indices posturaux d’attention intra- ou interspécifiques, celle-là même qui détermine cette flexibilité communicationnelle, peut provenir d’apprentissages sociaux dont les mécanismes restent méconnus. …”
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Harnessing new mHealth technologies to Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART trial): a protocol for a randomised controlled trial by Ben J Marais, Joel Negin, James Johnston, Virginia Wiseman, Greg J Fox, Thu Anh Nguyen, Binh Hoa Nguyen, Viet Nhung Nguyen, Justin Beardsley, Guy Barrington Marks, Kavindhran Velen, Tho Dang, Hoang Anh Nguyen, Dinh Hoa Vu, Thu Thuong Do, Cuong Pham Duc, Huu Lan Nguyen, Huu Thuong Pham, Warwick Britton

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Phase I study of pembrolizumab in combination with ibrutinib for the treatment of unresectable or metastatic melanoma by Yuan Yao, Yiyi Yan, Vera J. Suman, Allan B. Dietz, Courtney L. Erskine, Anastasios Dimou, Svetomir N. Markovic, Svetomir N. Markovic, Robert R. McWilliams, Heather N. Montane, Matthew S. Block, Matthew S. Block

“…The small molecule ibrutinib is a dual-target agent that inhibits Bruton’s Tyrosine Kinase (BTK) and Interleukin-2-inducible T-cell Kinase (ITK), a key regulator of Th2 immunity. …”
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Enhancement of colour quality, growth, and health status of rainbow Kurumoi fish Melanotaenia parva through dietary synthetic carotenoids supplementation by Nina Meilisza, Muhammad Agus Suprayudi, Dedi Jusadi, Muhammad Zairin Junior, I Made Artika, Nur Bambang Priyo Utomo

“…The results showed that carotenoid diets were able to increase growth, total carotenoids, percentages of chromatophores, vitamin A conversion, erythrocyte, leukocytes, packed cell volume (PCV), neutrophils, and hemoglobin (Hb) compared to the control. …”
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The role of artificial intelligence and machine learning in predicting and combating antimicrobial resistance by Hazrat Bilal, Muhammad Nadeem Khan, Sabir Khan, Muhammad Shafiq, Wenjie Fang, Rahat Ullah Khan, Mujeeb Ur Rahman, Xiaohui Li, Qiao-Li Lv, Bin Xu

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Effective semi-fed-batch saccharification with high lignocellulose loading using co-culture of Clostridium thermocellum and Thermobrachium celere strain A9 by Sreyneang Nhim, Sirilak Baramee, Chakrit Tachaapaikoon, Chakrit Tachaapaikoon, Patthra Pason, Patthra Pason, Khanok Ratanakhanokchai, Khanok Ratanakhanokchai, Ayaka Uke, Ruben Michael Ceballos, Akihiko Kosugi, Rattiya Waeonukul, Rattiya Waeonukul, Rattiya Waeonukul

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Kappa-carrageenan as immunostimulant to control infectious myonecrosis (IMN) disease in white shrimp Litopenaeus vannamei by Dian Febriani, . Sukenda, Sri Nuryati

“…The shrimp’s haemocyte count, phagocytes activity, phenoloxidase activity, and relative growth were 12±0.72×106 cell/mL; 34.67±0.58%; 0.511±0.10; and 86.15% respectively. …”
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Perencanaan Coverage Jaringan 5G Berdasarkan Propagasi Rugi Rugi Lintasan dan Shadowing by Made Niama Dwi Susila, Linawati Linawati, Nyoman Gunantara

“…Planning for the 5G network is done by calculating the cell radius with the path loss propagation model with the shadowing effect, calculating coverage, calculating the number of rooftop tower locations, and mapping on Google Earth. …”
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AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study by Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Chiung-Tzu Yen, Sheng-Hui Tang, Pin-Ching Pan, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang

“…ObjectiveThis study introduces innovative machine learning models using complete blood count with differential (CBC+DIFF) data—a routine, minimally invasive test that assesses immune response through blood cell measurements, critical for sepsis identification. …”
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Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g... by Reza Tohidi, Hoda Javaheri Bargourooshi, Arash Javanmard

“…The summary of gene ontology and related genes found for SE resistance was surprisingly comprehensive and covered the following topics: positive regulation of endopeptidase activity, interleukin‐8 production, chemokine production, interferon‐gamma production, interleukin‐6 production, positive regulation of mononuclear cell proliferation and response to interferon‐gamma. …”
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Exposure to copper metal enhances the tolerance of An. gambiae s.s. over multiple generations while reducing both fertility and fecundity in this primary malaria vector. [version 2... by Adam Gbankoto, Rousseau Djouaka, Camille Dossou, Louckman Monra Seidou, Ghislain T. Tepa-Yotto, Danahé Adanzounon, Genevieve Tchigossou, Innocent Djègbè, Aldo Emmanuel C. Glokpon, Massioudou Koto Yérima Gounou Boukari, Eric Tossou, Donald Hessou-Djossou

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SF1-specific deletion of the energy sensor AMPKγ2 induces obesity by Óscar Freire-Agulleiro, Ánxela Estévez-Salguero, Vitor Ferreira, Cassie Lynn Holleman, Julia García-Currás, Ismael González-García, Rubén Nogueiras, Manuel Tena-Sempere, Cristina García-Cáceres, Carlos Diéguez, Miguel López

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Mechanical Ventilator-Associated Pneumonia in the COVID-19 Pandemic Era: A Critical Challenge in the Intensive Care Units by Mircea Stoian, Adina Andone, Sergiu Rareș Bândilă, Danusia Onișor, Sergiu Ștefan Laszlo, Gabriela Lupu, Alina Danielescu, Dragoș-Florin Baba, Anca Meda Văsieșiu, Andrei Manea, Adina Stoian

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Multimodal data deep learning method for predicting symptomatic pneumonitis caused by lung cancer radiotherapy combined with immunotherapy by Mingyu Yang, Jianli Ma, Chengcheng Zhang, Liming Zhang, Jianyu Xu, Shilong Liu, Jian Li, Jiabin Han, Songliu Hu

“…ObjectivesThe pairing of immunotherapy and radiotherapy in the treatment of locally advanced nonsmall cell lung cancer (NSCLC) has shown promise. By combining radiotherapy with immunotherapy, the synergistic effects of these modalities not only bolster antitumor efficacy but also exacerbate lung injury. …”
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Clinical characteristics and prognosis of amyopathic dermatomyositis patients with interstitial lung disease: insights from a retrospective cohort by Yanan Ying, Tingting Wu, Long Wang, Yun Zhang, Yiming Yu, Zaichun Deng, Qunli Ding

“…Cox multivariate analysis revealed that age (p = 0.002), smoking status (p = 0.011), anti-melanoma differentiation-associated gene 5 (MDA5) antibody (p = 0.017), and white blood cell count (p = 0.004) were independent predictors of shorter survival. …”
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Safety and efficacy of PD-1 inhibitor (sintilimab) combined with transarterial chemoembolization as the initial treatment in patients with intermediate-stage hepatocellular carcino... by Lei Yu, Lan Zhang, Xin Xu, Zheng Wang, Jian Zhou, Jia Fan, Wentao Wang, Zhenggang Ren, Lixing Li, Peiran Huang

“…The study aims to evaluate the efficacy and safety of this treatment strategy for such patients.Methods In this single-arm, prospective, phase II study, we enrolled eligible patients with HCC who were treated with TACE plus programmed cell death protein 1 (PD-1) inhibitors (sintilimab) from April 2021 to February 2023. …”
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‘Des nouvelles de mon infortunée sœur’: Marie-Antoinette dans les lettres de l’archiduchesse Marie-Christine à l’empereur François by Catriona Seth

“…François II, qui succède à son père Léopold II, mort subitement le 1er mars 1792, n’a jamais rencontré celle qui languit au Temple puis à la Conciergerie avant de monter à l’échafaud. …”
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Disturbances of visual perception in non-demented patients with Parkinson’s disease by R. Timofejavaitė, V. Vilda, A. Liveikienė, R. Kaladytė-Lokominienė

“…Patients underwent ophthalmological examination which provided data on colour discrimination, contrast sensitivity, eye pressure, and retinal ganglion cell layer thickness (RGCL). The relations between minor hallucinations and clinical factors were investigated by comparison of PD and control groups, and PD group. …”
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The effect of rootstocks on morphological, physiological, and gene expression characters of citrus seedlings grown under drought condition by Nirmala Friyanti Devy, Siti Subandiyah, Sri Widyaningsih, Hardiyanto Hardiyanto, Farida Yulianti, Dita Agisimanto, Agus Sugiyatno, Mutia Dwiastuti

“…The drought did not affect cell membrane damage, although this did slightly increase the quantity of chlorophyll a, b, and carotenoids (P < 0.05). …”
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