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29861
Efficacy of medical thoracoscopy combined with fibrinolytic therapy in the treatment of complicated parapneumonic effusions and empyema
Published 2025-02-01“…Primary outcomes included changes in inflammatory markers (white blood cell count, C-reactive protein, and procalcitonin), imaging outcomes (resolution of pleural effusion, pulmonary inflammation, and the incidence of pleural thickening at three months), pulmonary function assessed by forced vital capacity (FVC), and in-hospital mortality. …”
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29862
Trade-Off Between Enzymatic Antioxidant Defense and Accumulation of Organic Metabolite Affects Salt Tolerance of White Clover Associated with Redox, Water, and Metabolic Homeostase...
Published 2025-01-01“…−</sup>), resulting in reduced cell membrane stability in two types of white clovers. …”
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29863
Enhancement of host defense against Helicobacter pylori infection through modulation of the gastrointestinal microenvironment by Lactiplantibacillus plantarum Lp05
Published 2025-01-01“…Microbial community structure in the stomach and intestines was evaluated through 16S rRNA gene sequencing.ResultsIn vitro studies showed Lp05 and H. pylori formed co-aggregates, with Lp05 potentially disrupting H. pylori cell structure, reducing its stomach colonization. …”
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29864
Imaging and Clinical Characteristics of 8 Cases of COVID-19 Complicated with Pneumomediastinum in Children
Published 2025-02-01“…At the onset of the disease, there were obvious shortness of breath, active oxygen therapy was recommended. When the white blood cell count and hypersensitivity CRP significantly increase, close attention should be paid to respiratory conditions. …”
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29865
Literatura carcerală din exil
Published 2010-12-01“…Une catégorie spéciale dans le paysage des mémorials roumains est celle des anciens détenus qui racontent par écrit leur experience en prison après avoir émigré, leurs témoignages paraissant tôt dans les pays de l’ouest, attirant ainsi l’attention sur le régime dictatorial du pays. …”
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29866
Presynaptic CRF1 Receptors Mediate the Ethanol Enhancement of GABAergic Transmission in the Mouse Central Amygdala
Published 2009-01-01“…The present study extends these findings using selective CRF receptor ligands, gene KO models, and miniature IPSC (mIPSC) analysis to assess further a presynaptic role for the CRF receptors in mediating ethanol effects in the CeA. In whole-cell patch recordings of pharmacologically isolated GABAAergic IPSCs from slices of mouse CeA, both CRF and ethanol augmented evoked IPSCs in a concentration-dependent manner, with low EC50s. …”
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29867
Impact of Comorbidities on Prognosis and Treatment Outcomes in Elderly Patients with Hodgkin Lymphoma
Published 2025-01-01“…For PFS, a white blood cell count > 8.48 G/L, a platelet count > 310.5 G/L, and advanced age (>73.5 years) were identified as significant adverse prognostic factors. …”
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29868
Transcriptomic and enzymatic analysis of peroxidase families at the early growth stage of halophyte ice plant (Mesembryanthemum crystallinum L.) under salt stress
Published 2025-01-01“…GO enrichment analysis indicated that differentially expressed genes (DEGs) with increased transcript abundance were associated with ion transport, antioxidant activity, and stress responses, while DEGs with decreased transcript abundance were linked to metabolic and biosynthesis processes such as ribosomal protein synthesis and cell wall formation. This indicates that salt stress hinders growth but enhances ion homeostasis and stress response mechanisms. …”
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29869
Klotho enhances stability of chronic kidney disease atherosclerotic plaques by inhibiting GRK2/PLC-β-mediated endoplasmic reticulum stress in macrophages via modulation of the ROS/...
Published 2024-12-01“…Western blotting detected associated protein expression, followed by cell-based experiments for validation. Compared with the Klotho-NC group, the plaque area and aortic lipid and renal fibrosis area were reduced in the Klotho-mimic group. …”
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29870
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29871
Prevalence of Food Insecurity and Its Associated Factors among Adult People with Human Immunodeficiency Virus in Ethiopia: A Systematic Review and Meta-Analysis
Published 2021-01-01“…Cluster of differentiation 4 CD4 count<350 cell/mm3 [AOR=1.29 (95% CI, 1.08, 1.54)], develop opportunistic infection [AOR=4.09 (95% CI, 2.47, 6.78)], rural residence [AOR=1.59 (95% CI, 1.09, 2.34)], and World Health Organization (WHO) clinical stages III and IV [AOR=1.98 (95% CI, 1.23, 3.19)] was among the significantly associated factors. …”
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29872
Role of IPF genetic risk loci in post-COVID-19 lung abnormalities: a cohort study
Published 2025-01-01“…This hypothesis-generating result suggests a possible protective effect of MUC5B in postinfectious lung abnormalities as compared with fibrosis in IPF, highlighting a plausible trade-off between its role in immune defence and epithelial cell function.…”
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29873
Efficacy and Safety of Recombinant Human Thrombopoietin (rhTPO) on Coagulation Function and Inflammatory Factors in the Treatment of Patients with Sepsis-Related Thrombocytopenia
Published 2025-02-01“…The Group R required significantly fewer red blood cell transfusions compared to the Group C and did not require Plt suspension ( P < 0.05). …”
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29874
Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus
Published 2019-01-01“…Levels of urinary neutrophil gelatinase-associated lipocalin (NGAL), retinol-binding protein (RBP), plasminogen activator inhibitor-1 (PAI-1), vascular cell adhesion molecule-1 (VCAM-1), and E-cadherin were detected, and their correlations with eGFR, plasma TNF-α, IL-6, endothelin-1 (ET-1), and 8-hydroxydeoxyguanosine (8-OHdG) were assessed. …”
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29875
Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2
Published 2025-01-01“…All these FRGs were significantly increased in patients with aortic aneurysm. Additionally, immune cell infiltration analyses revealed these FRGs were strongly correlated with the higher CD4+ Tem and macrophages fraction in AAD patients. …”
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29876
GAJARDOITE-(NH4), (NH4)As3+ 4O6Cl2[(Ca0.5□0.5)(H2O)5], A NEW MINERAL FROM THE KHOVU-AKSY DEPOSIT, EASTERN SIBERIA, RUSSIA
Published 2024-03-01“…Gajardoite-(NH4) is hexagonal, space group P6/mmm; the unit-cell parameters are as follows: a = 5.263(3), c = 16.078(5) Å, V = 385.8(5) Å3 , Z = 1. …”
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29877
Genetic Assessment of Living Kidney Transplant Donors: A Survey of Canadian Practices
Published 2025-01-01“…Major domains of the survey addressed general demographics, information sharing practices, effect of mode of inheritance on candidacy decision, having a policy for LKD genetic evaluation, and case scenarios covering the following conditions: autosomal dominant polycystic kidney disease (ADPKD), Alport syndrome, Fabry disease, familial focal and segmental glomerulosclerosis (FSGS), atypical hemolytic uremic syndrome (aHUS), autosomal dominant tubulointerstitial kidney disease (ADTKD), sickle cell, and apolipoprotein L1 mutation (APOL1). Participants: The questionnaire was sent to the living-donor assessment committee representative (nephrologist) in adult and pediatric kidney transplant centers across Canada. …”
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29878
Une norme pour la langue d’oc ? Les débuts d’une histoire sans fin
Published 2012-11-01“…Et, bien entendu, la question de fond, celle donc qui n'est posée qu'implicitement : qui est le mieux placé pour donner les justes réponses à ces questions ? …”
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29879
Induced Inflammatory and Oxidative Markers in Cerebral Microvasculature by Mentally Depressive Stress
Published 2023-01-01“…Cerebral microvasculature was isolated from the CRS and controls (n=10/group). mRNA and protein expressions of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), vascular cell adhesion molecule-1 (VCAM-1), and macrophage chemoattractant protein-1 (MCP-1) in the brain vessels were measured by real-time PCR and Western blot (n=10/group). …”
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29880
Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-labe...
Published 2025-02-01“…The NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr(NAIVE) study aims to assess the clinical efficacy and safety of NACT in combination with tislelizumab (a monoclonal antibody for programmed cell death protein 1) for advanced EOC.Methods and analysis The NAIVE study is an investigator-initiated, prospective, single-centre, open-label, randomised controlled trial for advanced EOC with the International Federation of Gynaecology and Obstetrics (FIGO) stage IIIc with a Suidan CT score of 3 or greater or a Fagotti laparoscopic score of 8 or greater; or FIGO stage IV. …”
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