Antibodies Against β2-Glycoprotein I Complexed With an Oxidised Lipoprotein Relate to Intima Thickening of Carotid Arteries in Primary Antiphospholipid Syndrome by P. R. J. Ames, J. Delgado Alves, L. R. Lopez, F. Gentile, A. Margarita, L. Pizzella, J. Batuca, G. Scenna, V. Brancaccio, E. Matsuura

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Reproducibility and repeatability of 18F-(2S, 4R)-4-fluoroglutamine PET imaging in preclinical oncology models. by Gregory D Ayers, Allison S Cohen, Seong-Woo Bae, Xiaoxia Wen, Alyssa Pollard, Shilpa Sharma, Trey Claus, Adria Payne, Ling Geng, Ping Zhao, Mohammed Noor Tantawy, Seth T Gammon, H Charles Manning

“…<h4>Methods</h4>Twenty mice bearing colorectal cancer cell line xenografts were injected with ~9 MBq of 18F-Gln and imaged in an Inveon microPET. …”
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Comparative analysis of long-term outcomes of primary posterior continuous curvilinear capsulorhexis in pseudoexfoliation syndrome by E.V. Egorova, V.V. Chernykh

“…., folds, fibrosis, sagging, lens epithelial cell proliferation), retrolental space, and anterior hyaloid membrane was assessed by OCT. …”
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CALR ins5-mediated clonal hematopoiesis causes severe hemolytic anemia in a female PGK1 Ser320Asn carrier by M. L. Morales, H. Cano, B. de la Morena-Barrio, J. L. Vives-Corrons, E. J. Cuenca-Zamora, P. Garrido-Rodríguez, C. Bento, J. Pereira, J. Martínez Nieto, T. H. Chen-Liang, J. L. Fuster, S. Caracena, M. L. Lozano, R. Teruel-Montoya, J. Corral, F. Ferrer-Marín

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The effect of calf muscular vein thrombosis on the prognosis within one year postoperatively of geriatric hip fracture patients: a propensity score-matched analysis by Jiabao Jiang, Fei Xing, Rong Luo, Zhao Chen, Hao Liu, Zhou Xiang, Xin Duan

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Inflammatory Monocyte Subsets Correlation with Iron Levels in Low Vitamin D Pediatric Transfusion-Dependent Thalassemia by Ghozali M, Matahari M, Cahyadi AI, Agustini SD, Ghrahani R, Reniarti L, Setiabudiawan B, Panigoro R

“…Considering the mechanisms of vitamin D activation and its potential interaction with monocytes, further investigation of its immunomodulatory role in transfusion-dependent thalassemia is essential.Purpose: This study evaluated monocyte subsets, population, and surface receptor expression (CD14, CD16, and HLA-DR), and their association with iron status and vitamin D levels in patients with transfusion-dependent thalassemia.Patients and Methods: Fifty lysed erythrocyte-heparinized whole blood samples from transfusion-dependent thalassemia patients were analyzed by flow cytometry and classified into three monocyte subsets: CD14++CD16- (classical), CD14++CD16+ (intermediate), and CD14+CD16++ (non-classical). Cell percentage referred to the monocyte subset population. …”
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Evaluating the Safety and Usability of an Over-the-Counter Medical Device for Adults With Mild to Moderate Hearing Loss: Formative and Summative Usability Testing by Megan Elizabeth Salwei, Shilo Anders, Carrie Reale, Jason M Slagle, Todd Ricketts, Matthew B Weinger

“…Participants had the most difficulty with the task of pairing the hearing aids to the cell phone. Participants also had difficulty distinguishing the right and left earbuds. …”
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Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators by S. Ali Naqvi, Graham C. Thompson, Ari R. Joffe, Jaime Blackwood, Dori-Ann Martin, Mary Brindle, Herman W. Barkema, Craig N. Jenne

“…A decision tree incorporating the proteins CRP, ferritin, SAA, regulated on activation normal T-cell expressed and secreted (RANTES), monokine induced by gamma interferon (MIG), and PCT demonstrated excellent specificity (0.920) and negative predictive value (0.882) for children with appendicitis. …”
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Étude des diarrhées en milieu périurbain à Abidjan par l’approche écosanté by Brama Koné, Mohamed Doumbia, Ibrahima Sy, Kouassi Dongo, Yveline Agbo-Houenou, Pascal Valentin Houenou, Benjamin Fayomi, Bassirou Bonfoh, Marcel Tanner, Guéladio Cissé

“…La tranche d’âge des moins de 5 ans était la plus affectée avec une prévalence de 14 %, suivie de celle des plus de 15 ans (6 %) et enfin des enfants de 5 à 15 ans (3 %).Les principaux facteurs de risques identifiés dans l’avènement des diarrhées sont, entre autres, le lieu de conservation de l’eau de boisson (P-value = 0,02), le récipient de conservation (p-value = 0,03) et le lieu d’installation des latrines dans les ménages (p-value = 0,02). …”
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Effects of melatonin supplementation on oxidative stress, and inflammatory biomarkers in diabetic patients with chronic kidney disease: a double-blind, randomized controlled trial by Sara Sadeghi, Amirahmad Nassiri, Monir Sadat Hakemi, Fatemeh Hosseini, Fatemeh Pourrezagholie, Fatemeh Naeini, Aylar Nadiri Niri, Hossein Imani, Hamed Mohammadi

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Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors by null Chunyan-Zou, null Yanpeng-He, null Changshun-Xie, null Fulai-Gao, null Xiaoli-Xie, null Xiukun-Chai, null Chenxi-He, null Dongqiang-Zhao

“…GO analysis results revealed that DEGs were involved in negative management of myocardial contraction, regulation of myocardial cell contraction, ethanol oxidation, cellular potassium ion homeostasis, and relaxation of cardiac muscle, and KEGG analysis showed that major DEGs were with cGMP-PKG signaling pathway. …”
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Amazonie vénézuélienne dans Voyage aux régions équinoxiales du Nouveau Continent (1799-1804) d'Alexandre de Humboldt : Nature et Homme  by Maurice Belrose

“…Tous les habitants sont soumis au même climat rude et débilitant, à la toute-puissance de la forêt équatoriale, mais celle-ci n'apparaît pas pour autant comme un « enfer vert ». …”
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Hydrogen production by water electrolysis: Advances, challenges and future prospects by Zheng ZHANG, Lingjun SONG

“…This paper investigates the progress and potential of various electrolysis methods, including alkaline water electrolysis, proton exchange membrane (PEM) electrolysis, anion exchange membrane (AEM) electrolysis, and solid oxide electrolyzer cell (SOEC) electrolysis, alongside emerging technologies such as seawater electrolysis and coupled hydrogen production. …”
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Virulence factor discovery identifies associations between the Fic gene family and Fap2+ fusobacteria in colorectal cancer microbiomes by Geicho Nakatsu, Duhyun Ko, Monia Michaud, Eric A. Franzosa, Xochitl C. Morgan, Curtis Huttenhower, Wendy S. Garrett

“…Exposure of a F. animalis strain to a colon adenocarcinoma cell line increases gene expression of fusobacterial Fic and virulence-associated adhesins. …”
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Knowledge, attitudes, and practices toward leishmaniasis and one health: a cross-sectional study among medical and veterinary professionals by Yasir Khan, I-Chen Lin, Sundus Khan, Mehtab Kanwal, Abdul Wajid, Aamir Khan, Fazal Noor, Ali Madi Almajwal, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Abdul Qadeer

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Adherence to Azathioprine/6-Mercaptopurine in Children and Adolescents with Inflammatory Bowel Diseases: A Multimethod Study by Mervat M. Alsous, Ahmed F. Hawwa, Cameron Imrie, Andras Szabo, Eman Alefishat, Rana Abu Farha, Mohammad Rwalah, Rob Horne, James C. McElnay

“…Medication adherence in 47 children (age range 3 to 17 years) with IBD in three centers in Northern Ireland and Jordan was assessed via subjective (parent and child versions of the Medication Adherence Report Scale (MARS) specific questionnaire) and objective methods, that is, high-performance liquid chromatography (HPLC) determination of the 6-mercaptopurine (6-MP) and azathioprine (AZA) metabolites in packed red blood cell samples taken during a clinic visit. Beliefs about prescribed medicines were also assessed in parents/guardians using the Beliefs about Medicines Questionnaire (BMQ). …”
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Mechanism of <italic>Hindu Datura</italic> in the Treatment of Rheumatoid Arthritis from the Perspective of Network Pharmacology by Changlong FU, Yangyang MEI, Xihai LI, Zhiwei QIU, Changxing CHEN, Chunsong ZHENG

“…Objective:To construct the active component target of <italic>Hindu datura</italic> and the disease target of rheumatoid arthritis by using network pharmacology, to predict the specific molecular signal and pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis, and to analyze its potential therapeutic target and molecular mechanism.Methods:All the chemical components of <italic>hindu datura</italic> were summarized and screened through Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP)database, retrieval was performed with the preset oral bioavailability(OB)≥30%and drug like(DL)≥0.18.Uniprot database was used to screen the entire correlation basis of the effective chemical compound.After screening the disease target with"rheumatoid arthritis"as the retrieval word using GeneCards and OMIM database, the superimposed target area between the drug target of <italic>hindu datura</italic> and the disease target of rheumatoid arthritis was summarized and analyzed, and it could be used as the prediction target gene of <italic>hindu datura</italic> for treating rheumatoid arthritis.Network targets were constructed and analyzed for the exported data based on Cytoscape 3.7.1 software and STRING 7.8 database.Finally, GO functional enrichment analysis and KEGG signal pathway analysis were performed to further screen the main targets and signal pathways.Results:①Through screening and analysis, 27 effective compounds, 318 corresponding target genes and 125 predicted target genes were obtained for the treatment of rheumatoid arthritis.②The core genes in PPI network mainly included JUN, AKT1, RELA, MAPK1, etc.③GO functional enrichment analysis showed that the biological process(BP)for the treatment of rheumatoid arthritis by <italic>hindu datura</italic> mainly involves response to lipopolysaccharide, response to lipopolysaccharide, response to molecule of bacterial origin, response to metalion, response to oxidative stress, response to steroid hormone, cellular response to oxidative stress, reactive oxygen species metabolic process, response to oxygen levels, etc..The cell component(CC)consisted of membrane raft, membrane region, plasma membrane raft and presynaptic membrane; molecular functions(MF)mainly involved the nuclear receptor activity, transcription factor activity(direct ligand regulated sequence-specific DNA binding), steroid hormone receptor activity, cytokine receptors, cytokine activity, DNA-binding transcription activator activity, RNA polymeraseⅡtranscription factor binding, kinase regulator activity, receptor ligand activity, etc.The analysis of KEGG signaling pathway showed that the obvious pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis may involve IL-17 signaling pathway, TNF signal pathway, HIF-1signalpathway, Toll-like receptor signal pathway, etc.Conclusion:The potential mechanism of <italic>hindu datura</italic> for the treatment of rheumatoid arthritis is to exert anti-inflammatory, analgesic and antioxidant effects, which involve a number of interactive signal pathways.…”
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EVALUASI KASUS KARSINOMA SEL BASAL DI MAKASSAR PERIODE JANUARI 2017-DESEMBER 2019 by Fonny Josh, Asrul Mappiwali, Tommy Hermawan Sukamto

“…Abstrak: Latar Belakang:  Karsinoma  Sel  Basal  atau  Basal  Cell  Carcinoma  (BCC) adalah jenis kanker kulit yang paling umum terjadi pada manusia. …”
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Application of green silver nano-particles as anti-bacterial and photo-catalytic degradation of azo dye in wastewater by Zainab Haider Ali, Lubna Abdulazeem, Wurood Alwan Kadhim¹, Mazin H. Kzar³, Osamah J. Al-sareji

“…The action can be ascribed to the unique biological and physicochemical features of AgNPs, which facilitate the disruption of bacterial cell membranes. The UV-visible analysis solution after the introduction of AgNPs indicated that the decrease in the absorbance peak of methyl red was attributed to the existence of silver nano-particles. …”
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Three-dimensional linkage analysis with digital PCR for genome integrity and identity of recombinant adeno-associated virus by Tam Duong, Michele Firmo, Chien-Ting Li, Bingnan Gu, Peng Wang

“…This cost-effective approach, akin to the setup of traditional 1D or 2D dPCR, holds the potential to advance the application of rAAV in cell and gene therapy for the treatment of human diseases.…”
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