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29561
Valorisation et sauvegarde de l’identité socio-culturelle fang de Guinée Équatoriale et du Gabon dans les romans Herencia de Binendee et le pacte d’Afia
Published 2025-01-01“…Le roman du Gabonais, Maurice Okoumba-Nkoghe, Le pacte d’Afia (2009/2022) jette les bases du féminisme africain tandis que Herencia de Bindendee (2016) de la Guinéo-équatorienne, Trifonia Melibea Obono interroge les mentalités africaines patriarcales en général et celles guinéo-équatoriennes en particulier. À partir d’une approche féministe et sémiologique, la présente étude interroge les mécanismes romanesques des auteurs par lesquels se déploie le fang dans les romans étudiés comme en témoigne, leur titrologie. …”
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29562
Liraglutide Regulates the Kidney and Liver in Diabetic Nephropathy Rats through the miR-34a/SIRT1 Pathway
Published 2021-01-01“…Additionally, the liraglutide-treated DN rats had a clear hepatic structure, a lower degree of steatosis, and mild inflammatory cell infiltration. Conclusion. Liraglutide, through its effect on the miR-34a/SIRT1 pathway, may have a protective role in the kidney and liver of DN rats.…”
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29563
Construction of prokaryotic system for expression of porcine circovirus type 2 ORF-2 gene fragment
Published 2024-03-01“…It was shown that the positivity coefficient of producer strain cell lysates averaged to 4.34 (p < 0.005). The recombinant rCap protein is suitable for serological diagnosis and is also of interest as a vaccine component, which is the goal of our further studies.…”
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29565
Perianal Paget’s Disease: The 17-Year-Experience of a Single Institution in Taiwan
Published 2019-01-01“…Other synchronous or metachronous malignancies included cholangiocarcinoma, urothelial carcinoma, anorectal small-cell carcinoma, and unknown hepatic malignancy. One primary PPD patient died from the metastases of invasive Paget’s disease while 3 secondary PPD patients died from the metastases of CRCs during follow-up. …”
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29567
Biometabolic Distribution of Tc-3PRGD2 and its Potential Value in Monitoring Chemotherapeutic Effects
Published 2015-12-01“…Eighteen rabbits with 27 implanted VX2 squamous cell tumors were randomly divided into a nontreated control group (NTG, n = 8; 12 tumors) and a treatment group (TG, n = 10; 15 tumors). 99m Tc-3PRGD2 imaging was performed prior to cisplatin injection and repeated on days 0,1, 7, and 14 postinjection. …”
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29568
The effect of conservation in various cryoprotectants on the properties and morphological structure of the umbilical cord arteries
Published 2022-09-01“…The presence of statistically significant differences between the control and frozen UCAs was shown for Young's modulus (p < 0.05; 6.9 [6.8; 7.0] for the native artery; 2.3 [2.0; 2.6] for the artery preserved with the use of dextran, DMSO and human albumin; 2.3 [1.4; 3.2] for the artery preserved in glycerin and 0.8 [0.6; 1.0] – in propanediol, respectively).Conclusion. 1) Freezing and storage of UCA at 5 % dextran, 10 % DMSO and 7.5 % HSA does not lead to a significant change in the morphology of vascular membranes and cell nuclei; 2) The preservation of type I collagen according to the results of IHC is qualitatively reduced from a conditional indicator of +2 to +1 for frozen agroindustrial complexes compared with control ones; 3) Conservation leads to a significant decrease in the modulus of elasticity of the walls of the agroindustrial complex compared with control vessels (p < 0.05).…”
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29569
Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coron...
Published 2020-01-01“…Background. The white blood cell count to mean platelet volume ratio (WMR) is an indicator of inflammation in patients with atherosclerotic disease. …”
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29570
Molecular Characterization and Clinical Characteristics of m5C-Based RNA Methylation in Spinal Cord Injury: Validated by qPCR
Published 2022-01-01“…Analysis of the correlation between the gene sets of m5C-based regulators of RNA modification and immune-cell infiltration and immune response revealed Dnmt1, DNA methyltransferases 3A (Dnmt3a), Mbd2, and Ung to be positive regulators of the immune microenvironment, and Zbtb4 may negatively regulate the immune environment. …”
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29571
An eCIRP inhibitor attenuates fibrosis and ferroptosis in ischemia and reperfusion induced chronic kidney disease
Published 2025-01-01“…Extracellular cold-inducible RNA-binding protein (eCIRP) is a stress response protein involved in acute inflammation, tissue injury and regulated cell death. However, the role of eCIRP in chronic inflammation and tissue injury has not been elucidated. …”
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29572
THE RESULTS OF MODULAR ENDOPROSTHESIS OF PERIACETABULAR REGION IN TUMOR LESIONS OF THE ACETABULUM AND HIP JOINT
Published 2019-06-01“…Primary bone cancers were in 19 (63%) patients, giant cell tumors in 5 (17%), locally advanced soft tissue sarcoma in 1 (3%), solitary metastases of kidney cancer in 2 (7%), and recurrent sarcomas after previous surgical treatment in 3 (10%) patients.Results. …”
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29573
Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination...
Published 2023-09-01“…Secondary outcomes are RBD antibody levels at 12 weeks postbooster vaccination, participant global assessments of disease activity, blood films, full blood count and lactate dehydrogenase levels, impact on quality of life, self-reported adherence with request to temporarily pause or continue BTKi, T cell response against spike protein and relative neutralising antibody titre against SARS-CoV-2 viral variants. …”
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29575
Anticancer activity of mixed Graphene/Carbone nanotubes reinforced Sulfur-Containing polyketoamine nanocomposites
Published 2025-01-01“…Methylene blue staining confirmed the suppression of cancer cell growth, particularly with PKA/GNS/MWCNTsd, highlighting their potential for clinical applications.…”
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29576
Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis
Published 2025-02-01“…However, the role of Erbin in coagulation disorders in sepsis and the relationship between Erbin and macrophage regulation of coagulation function are still unclear.Methods: At the cellular level, macrophages were treated with lipopolysaccharide (LPS) or MEK inhibitor (PD98059), protein expression levels were detected by Western blot, co-immunoprecipitation (Co-IP), and immunofluorescence, mRNA expression levels were detected by quantitative real-time polymerase chain reaction (qPCR), and the concentration of tissue factor (TF) in cell supernatant was detected by enzyme linked immunosorbent assay (ELISA). …”
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29577
Hossegor (Landes), une station au cœur des réseaux de villégiature
Published 2012-04-01“…En conclusion, à côté de l’histoire officielle des stations balnéaires – une histoire au premier degré que les archives documentent relativement facilement – on ne peut passer à côté d’une autre histoire, plus souterraine mais qui a largement autant d’influence : celle des réseaux.…”
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29578
Investigating Escherichia Coli (E. Coli) Contamination of Street Foods in Manjari Kabale District.
Published 2025“…The study was investigating Escherichia coli (E. coli) contamination of the street foods in mwanjari market in nyakiharo, cell, mwanjari parish, kabale municipality. The term "street food" refers to food and beverages that are served by hawkers or other vendors in public areas like parks, marketplaces, and fairs. …”
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29580
An Update on African Trypanocide Pharmaceutics and Resistance.
Published 2023“…Resistance to eflornithine is caused by the deletion or mutation of TbAAT6 gene which encodes the transmembrane amino acid transporter that delivers eflornithine into the cell, thus loss of transporter protein results in eflornithine resistance. …”
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