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29261
Dual-Polarized Wideband Filtering Antenna Array Based on Stacked-PCB Structure
Published 2025-01-01“…The filtering effect is realized by corrugating the tapered slotlines, which provides effective, space-saving integration of the filters that fit into a half-wavelength lattice. According to unit-cell simulations, the proposed antenna array operates at 6–18.5 GHz, and the stopband extends from 21 GHz to 37 GHz. …”
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29262
Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2
Published 2025-01-01“…We also created Nrf2 knockdown (KD) BV2 microglia to investigate the role of cell-specific Nrf2 in Cd-induced microglial activation. …”
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29263
Vascularized fibular grafting following tumor resection demonstrates acceptable long-term outcomes in Denmark: a national retrospective cohort study
Published 2025-01-01“…The indications were 13 cases of Ewing sarcoma, 12 cases of osteosarcoma, and 2 cases of giant cell tumor. The median age at surgery was 16 years (interquartile range [IQR] 10–18), and the median follow-up was 82 months (IQR 32–101). …”
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29264
Dynamic changes in peripheral blood lymphocyte trajectory predict the clinical outcomes of sepsis
Published 2025-02-01“…Multivariable regression demonstrated that age, Acute Physiology and Chronic Health Evaluation-II score, heart rate, natural killer cell count, infection source, and lymphocyte trajectory phenotype were independent predictors of 28-day mortality. …”
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29265
From bench to bedside: Developing CRISPR/Cas-based therapy for ocular diseases
Published 2025-03-01“…This system has contributed to the development of representative disease models, including animal models, organoids, and cell lines, thereby facilitating investigations into the pathogenesis of disease-related genes. …”
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29266
Experimental and numerical assessment of water-based photovoltaic/thermal collectors with varied tubular absorber cross-sections
Published 2025-01-01“…The performance of PV/T was evaluated in terms of governing parameters, including the mass flow rate (m˙), solar irradiance (I), heat gain, maximum power (Pmax), Reynolds number (Re), thermal (ηth) and electrical (ηel) efficiency, the temperature difference between the outlet and inlet water (To-Ti), the average cell temperature, and total efficiency (ηtotal). …”
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29267
LINC01271 promotes fracture healing via regulating miR-19a-3p/PIK3CA axis
Published 2025-01-01“…Luciferase reporter assays, RIP experiments, and RNA pull-down assays were utilized to verify the target relationships between LINC01271 and miR-19a-3p, as well as between miR-19a-3p and PIK3CA. Cell proliferation and apoptosis were assessed using CCK-8 assays and flow cytometry. …”
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29268
Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era
Published 2025-01-01“…The implementation of transcriptomic and proteomic analysis, even at the single-cell level, has widened the horizons, complementing the genomic alterations with their transcriptional and translational bond. …”
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29269
Antifungal Activity of Genistein Against Phytopathogenic Fungi <i>Valsa mali</i> Through ROS-Mediated Lipid Peroxidation
Published 2025-01-01“…Transmission electron microscopy analysis revealed leakage of cellular contents, blurred cell walls, ruptured membranes, and organelle abnormalities. …”
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29270
Innovations in bioethanol production: A comprehensive review of feedstock generations and technology advances
Published 2025-01-01“…Batch, fed-batch, and continuous fermentation techniques are used, with advances such as immobilized cell reactors and genetic engineering improving output and efficiency. …”
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29271
Radiocobalt-Labeling of a Polypyridylamine Chelate Conjugated to GE11 for EGFR-Targeted Theranostics
Published 2025-01-01“…[<sup>57</sup>Co]Co-TZTPEN-GE11 showed high stability in PBS (pH 5) and specific uptake in EGFR-positive cell lines. Disappointingly, no tumor uptake was observed in EGFR-positive tumor-bearing mice, with most activity being accumulated predominantly in the liver, gall bladder, kidneys, and spleen. …”
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29272
Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats
Published 2025-01-01“…Although the levels of toxicants in the mainstream are significantly lower than those observed in tobacco smoke, some recent studies have raised concerns about potential health risks associated with their use, particularly regarding their effects on male gonadal function, which remain largely unexplored.MethodsAdult male Sprague-Dawley rats were exposed, whole body, 5 days/week for 4 weeks to HnB mainstream.ResultsThe expression of the cell cycle regulators Bax/Bcl-2 ratio is not affected, along with no changes in p-38. …”
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29273
Psoriasis increases the risk of Sjögren’s syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis
Published 2025-01-01“…Transcriptomic analysis revealed potential shared pathogenesis of psoriasis and SS involving cellular proliferation, immune cell recruitment, cytokine secretion, and the interferon response to viral infections. …”
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29274
Insights into bioactivity guided chemical profiling of Ziziphus jujuba Mill. fruits wild-growing in Montenegro
Published 2025-01-01“…The results of antifungal activity showed lower potential to inhibit growth of pathogenic fungi than bacteria, whereas cytotoxicity assay showed extracts have no effects towards HaCaT skin cell line.The n-butanol fraction had the overall most promising activity, and therefore was subjected to more in depth chemical analysis.…”
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29275
Effect of prolonged starvation on nutrition utilization and transcriptional responses in Pacific oyster (Crassostrea gigas)
Published 2025-03-01“…In contrast, immunological functions initially decreased before increasing, whereas functions related to cell growth and survival showed a consistent downward trend. …”
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29276
Long-term real-world evidence of CPX-351 of high-risk patients with AML identified high rate of negative MRD and prolonged OS
Published 2025-02-01“…We also observed a trend toward a better median OS in patients who underwent hematopoietic stem cell transplantation with MRD <10–3 (not reached vs 26.0 months; P = .06). …”
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29277
Standardization of the Agar Plate Method for Bacteriophage Production
Published 2024-12-01“…The model’s validation showed a strong inverse correlation between plaque size and minimum-lawn cell clearing PFUs (MCPs; R² = 98.91%) and identified an optimal inoculum density that maximizes yield while minimizing the evolution of resistant mutants. …”
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29278
Effect of beetroot extract (beta vulgaris) against olanzapine on the pituitary, thyroid, and fertility in adult white male rats
Published 2024-12-01“…OLZ caused atrophy of follicular epithelium in the thyroid gland and shrunken seminiferous tubules, with disorganized germinal epithelium in the testis; however, beetroot extract treatment resulted in normal testicular histology, characterized by regular tubules with stratified germinal epithelium and Leydig cell clusters. However, some sperm aggregation was observed in the tubular luminae. …”
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29279
An Attenuated Cytomegalovirus Vaccine with a Deletion of a Viral Chemokine Gene Is Protective against Congenital CMV Transmission in a Guinea Pig Model
Published 2013-01-01“…MIP deletion virus replicated with wild-type kinetics in cell culture but was attenuated in nonpregnant guinea pigs, demonstrating reduced viremia and reduced inflammation and histopathology (compared to a control virus with an intact GPCMV MIP gene) following footpad inoculation. …”
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29280
Traditional Knowledge and Efficacy Analysis of an Emerging Medicinal Food Plant: <i>Disporopsis aspersa</i>
Published 2024-12-01“…In vitro evaluations of its antioxidant and anti-inflammatory activities demonstrated that the ethanolic extract exhibited low cytotoxicity against mouse RAW 264.7 murine macrophages cell line at concentrations of 0–120 μg/mL. The IC<sub>50</sub> for nitric oxide (NO) scavenging activity was 72.7 ± 7.43 μg/mL, showing dose dependence. …”
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