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29001
Forecasting Asparaginase Need and Cost for Childhood Cancer Using ACCESS FORxECAST
Published 2025-01-01Get full text
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29002
Surface modification of AISI 316L stainless steel by applying single and multilayer coatings: Study of elastic modulus and antibacterial properties
Published 2025-01-01“…Corrosion measurements indicated the formation of a galvanic cell due to the layers in the coated samples, and the substrate did not corrode until the coating was fully degraded.…”
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29003
Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel
Published 2024-12-01“…<b>Background/Objectives:</b> Transient Receptor Potential Melastatin 8 (TRPM8) is a non-selective, Ca<sup>2+</sup>-permeable cation channel involved in thermoregulation and other physiological processes, such as basal tear secretion, cell differentiation, and insulin homeostasis. The activation and deactivation of TRPM8 occur through genetic modifications, channel interactions, and signaling cascades. …”
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29004
Targeting the CLK2/SRSF9 splicing axis in prostate cancer leads to decreased ARV7 expression
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29005
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29006
Genome-scale evolution in local populations of wild chimpanzees
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29007
Primary Hyperparathyroidism-Phosphaturic Mesenchymal Tumour: An Unusual Association and a Probable Syndrome
Published 2025-01-01“…Microscopy revealed a benign spindle cell tumour with a vasoformative pattern and areas of grungy calcification. …”
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29008
HMOX1 as a potential drug target for upper and lower airway diseases: insights from multi-omics analysis
Published 2025-01-01“…Causal inference between candidate genes and upper and lower airway diseases (CRSwNP, allergic rhinitis (AR), and asthma (AS)) was conducted using bidirectional two-sample Mendelian randomization (TwoSampleMR) analysis. Single-cell RNA sequencing (scRNA-seq) data were used to determine the cellular localization and intercellular interactions of candidate genes. …”
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29009
The ratio of COL2A1:COL1A1 in dartos tissue patients with hypospadias
Published 2025-01-01“…While the COL2A1:COL1A1 ratio is recognised as a measure of cell differentiation, there is yet to be a study specifically examining this ratio in hypospadias. …”
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29010
Alterations of Dopamine-Related Transcripts in A11 Diencephalospinal Pathways after Spinal Cord Injury
Published 2021-01-01“…Meanwhile, A11 neurons in the brain were explicitly isolated by laser capture microdissection, and single-cell qPCR was employed to evaluate mRNA levels in the soma. …”
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29011
Urine metabolic profile in rats with arterial hypertension of different genesis
Published 2024-05-01“…The metabolome is a set of low-molecular substances available for detection in a sample and representing intermediate and final products of cell metabolism. Changes in the content and ratio of metabolites in the sample mark the corresponding pathogenetic mechanisms by highlighting them, which is especially important for such a multifactorial disease as arterial hypertension. …”
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29012
Effects of POPs-induced SIRT6 alteration on intestinal mucosal barrier function: A comprehensive review
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29013
Development and validation of a risk prediction model for acute kidney injury in coronary artery disease
Published 2025-01-01“…Key predictors included surgical department admission, eGFR, hemoglobin, chronic kidney disease history, male sex, white blood cell count, age, left ventricular ejection fraction, acute myocardial infarction at admission, and congestive heart failure history. …”
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29014
HEAL-Dengue: Hospital- based Exploration, Analysis and Learning about Dengue Outcomes (HEAL-D-ALDO)
Published 2025-02-01“…A significant association between female gender and the necessity for packed cell volume and fresh frozen plasma transfusion was observed (OR (95% CI: 10.26 (2.23 – 96.24), p =0.0005).The significant risk factors for mortality were: presence of ascites, pleural effusion, organ dysfunction, need for PCV, FFP and platelet megaunit transfusion. …”
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29015
Molecular Signature of miR-34a/NEAT-1/p53 Axis in Mycosis Fungoides
Published 2024-01-01“…Mycosis fungoides (MF) is a type of cutaneous T-cell lymphoma where red rash exists on the skin. …”
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29016
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29017
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29018
Reassessing Nutritional Supplementation Program: The Impact of Maternal Vitamin B12 Levels on Feto-Maternal Outcomes
Published 2023-12-01“…Vit B12 is an important cofactor for enzymatic reactions related to DNA synthesis, folate, and cell metabolism. While folate deficiency has been acknowledged in not only the prevention of neural tube defects and other adverse pregnancy outcomes, the effects of low vit B12 status have not been well defined. …”
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29019
Bibliometric analysis of rhein in the treatment of tumors
Published 2025-02-01“…Research hotspots include the promotion of apoptosis, endoplasmic reticulum stress, inhibition of proliferation, drug resistance, and nanoparticles.ConclusionRhein exerts antitumor effects by inducing cell apoptosis, controlling metastasis, and inhibiting proliferation. …”
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29020
Genetic basis of depressive disorders
Published 2019-07-01“…The results of the second approach (GWAS and WES) revealed that the PCLO, SIRT1, GNL3, GLT8D1, ITIH3, MTNR1A, BMP5, FHIT, KSR2, PCDH9, and AUTS2 genes predominantly responsible for neurogenesis and cell adhesion are involved in liability to depression. …”
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