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28981
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28982
PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) DENGAN HYPERCOAGULABLE STATE
Published 2018-07-01“…Hal ini disebabkan oleh kelainan seluler karena mutasi somatik pada hematopoetic stem cell yang menyebabkan terjadinya defisiensi berbagai jenis protein yang diperlukan bagi pembentukan glycosylphosphatidylinositol (GPI) anchored, yakni antara lain yang tersering decay accelerating factor (DAF, CD55) dan membrane inhibitor of reactive lysis (MIRL, CD59). …”
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28983
Endometriosis-associated Ovarian Cancer, from Risk Factors to Survival Rate: A Systematic Review and Meta-Analysis
Published 2025-01-01“…In our study, EAOC exhibited a 7.34% cancer incidence. While clear cell and endometrioid types were more common in EAOC than in the non-EAOC group, the low-grade serous type was the most prevalent malignancy.Patients with early-stage EAOC have a 1.7 times higher 5-year survival rate compared with non-EAOC groups. …”
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28984
Transcriptomic Analysis of Pathogenicity Genes in Sclerotinia sclerotiorum Affecting Brassica napus
Published 2024-09-01“…These results demonstrated that S. sclerotiorum modulates some genes involved in disease induction (e.g., cell wall-degrading enzymes, biosynthesis of secondary metabolites & metabolic pathways) to infect its host plant.…”
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28985
Internal transcribed spacer metagenomics data unravelling the core fungal community structure residing the wheat and maize rhizosphereNCBINCBINCBI
Published 2025-02-01“…Plants are colonized by a vast array of microorganisms that outstrip plant cell densities and genes, thus referred to as plant's second genome or extended genome. …”
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28986
LIM-kinase 1 effects on memory abilities and male courtship song in Drosophila depend on the neuronal type
Published 2023-06-01“…At the same time, LIMK1 was observed in cell bodies, such as DAN clusters regulating memory formation in CCSP. …”
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28987
Results of experimental infection of vaccinated and non-vaccinated ducklings with duck hepatitis virus
Published 2022-12-01“…Pathomorphological studies carried out post experimental infection indicate that duck hepatitis virus induces pathogenic effect not only in birds’ digestive organs (the liver, in particular) but also causes degenerative changes in central and peripheral immune organs: in cloacal bursa, thymus and third eyelid gland, that may be manifested as deficiency of B- and T-cell immunity and requires further studies. It has been shown that in case of immunization of 3-day-old ducklings, the experimental vaccine induces antibody-mediated immune response, no harmful effect is produced on poultry if a tenfold dose is administered which indicates its safety, and the vaccine ensures protection against infection with a control virulent strain of hepatitis virus.…”
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28988
Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis
Published 2025-01-01“…Enrichment analysis indicated that the key genes were associated with oxidative stress, reactive oxygen species, lipid and atherosclerosis, and cell migration-related pathways. Then, 6 feature genes (HSPA8, NCF2, FOS, KLF4, THBS1, and HSPA1A) related to OS were identified for IS. …”
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28989
Exploration of the molecular mechanism behind a novel natural genic male-sterile mutation of 1205A in Brassica napus
Published 2025-02-01“…Metabolic fluctuations associated with the fertility gene were observed, particularly in processes related to aborted tapetal programmed cell death (PCD), which may contribute to reduced pollen fertility with abnormal pollen exine. …”
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28990
Outcomes of Six-Dose High-Dose Cytarabine as a Salvage Regimen for Patients with Relapsed/Refractory Acute Myeloid Leukemia
Published 2017-01-01“…Relapsed/refractory acute myeloid leukemia (RR-AML) is associated with poor prognosis and long-term disease-free survival requires allogeneic hematopoietic cell transplantation (allo-HCT). Limited data exists, regarding the optimal regimen to obtain remission prior to allo-HCT. …”
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28991
Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better
Published 2022-01-01“…Only in cancer types with higher TMB (category I), such as melanoma, colorectal cancer, bladder cancer, and non-small cell lung cancer, the associations between TMB-H and ICB treatment outcomes were less affected by TMB cut-off selection. …”
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28992
The genomes of Scedosporium between environmental challenges and opportunism
Published 2023-12-01“…By contrast, several features in Microascaceae and Scedosporium were detected that might have a dual role in responding to environmental challenges and allowing colonization of the human body, including chitin, melanin and other cell wall related genes, proteases, glutaredoxins and magnesium transporters. …”
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28993
Elucidation of the Molecular Interaction between miRNAs and the Gene, Involved in Acute Myeloid Leukemia, by the Assistance of Argonaute Protein through a Computational Approach
Published 2015-06-01“…Acute myeloid leukemia is a well characterized blood cancer in which the unnatural growth of immature white blood cell takes place, where several genes transcription is regulated by the micro RNAs (miRNAs). …”
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28994
Transcript Changes of Placental Tissue in Gestational Diabetes Mellitus Based on Transcriptome Sequencing
Published 2025-01-01“…GO enrichment analysis revealed that DEGs were primarily associated with biological processes, such as cellular processes, biological regulation, regulation of biological processes, and response to stimuli. Cell component enrichment analysis indicated their association with cellular anatomical entities and protein-containing complexes. …”
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28995
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28996
Combined extracts of Syzygium aromaticum (Clove) and Xylopia aethiopica (Negro pepper) seeds inhibit testosterone propionate-induced benign prostatic hyperplasia in Wistar rats
Published 2024-12-01“…Abbreviations: BPH: benign prostatic hyperplasia; CAT: catalase; DTH: dihydrotestosterone; GPx: glutathione peroxidase; HDL-Chol: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; MDA: malondialdehyde; NC: normal control; PI: prostatic interstitium; PVC: packed cell volume; PSA: prostate specific antigen; SOD: superoxide dismutase; TP: testosterone propionate; TAG: triacylglycerol…”
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28997
Association between serum pyridoxal 5′-phosphate levels and chronic obstructive pulmonary disease: findings based on NHANES 2005–2010
Published 2025-01-01“…ObjectiveVitamin B6 is involved in regulating a variety of biological reactions in cell metabolism, and possesses antioxidant and anti-inflammatory biological functions. 5′-pyridoxal phosphate (PLP) is the main biologically active form of vitamin B6. …”
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28998
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28999
Peut-il y avoir une vie sobre sans travail sobre ?
Published 2024-01-01“…Parmi les facteurs permettant d’identifier les vulnérabilités et leur inégale distribution, le travail joue un rôle clé.Nous poserons qu’un travail peut être dit sobre s’il respecte les conditions suivantes : 1) les travailleurs participent aux décisions concernant leur production et l’organisation de leur activité ; 2) celles-ci répondent à l’intérêt général ; 3) ils prennent en compte l’impératif de limiter les empreintes de leurs activités ; 4) les évolutions du droit du travail rendent pérenne cette configuration.Pour tester la pertinence de ce cadre d’analyse, nous mobilisons les résultats d’une étude empirique portant sur des travailleurs « engagés » du numérique : a) les premiers ont mis en oeuvre des projets/organisations de plateformes coopératives numériques ; b) les seconds, salariés d’une multinationale, essayent, dans leurs pratiques quotidiennes, de mener des activités sobres. …”
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29000
Analysis of the morbidity characteristics and related factors of pulmonary nodules in patients with type 2 diabetes mellitus: a retrospective study
Published 2025-01-01“…Moreover, decreased islet B-cell function and smoking may contribute to the presence of PNs with a diameter of over 5 mm.…”
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