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28741
A Novel Insight into Paraptosis-Related Classification and Signature in Lower-Grade Gliomas
Published 2022-01-01“…Paraptosis is defined as a nonapoptotic form of programmed cell death, which is gradually focused on patients with gliomas to develop treatment options. …”
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28742
Preventive Effect of Liupao Tea Polyphenols on HCl/Ethanol-Induced Gastric Injury in Mice
Published 2020-01-01“…Observations of the pathology revealed that LTPs could alleviate cell necrosis and gastric mucosal injury in mice with gastric injury. …”
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28743
Integrated transcriptome and metabolome analysis of liver reveals unsynchronized growth mechanisms in blunt-snout bream (Megalobrama amblycephala)
Published 2025-01-01“…These more abundant DEMs were prominently enriched in pathways associated with cell proliferation and energy metabolism (Oxidative phosphorylation, mTOR signaling pathway and FoxO signaling pathway). …”
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28744
Histopathological and Immunohistochemical Evaluation of Methotrexate-Induced Gonadal Damage in Rats: Role of SCF, mTOR, and SIRT-1
Published 2024-12-01“…In addition, the immunoreactivity intensities of stem cell factor (SCF), mechanistic target of rapamycin (mTOR), and SIRT-1 in both tissues were measured by immunohistochemistry. …”
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28745
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28746
A Nodulation-Proficient Nonrhizobial Inhabitant of Pueraria phaseoloides
Published 2019-01-01“…We isolated a bacterium (Sub1) from Pueraria phaseoloides, of coccobacillus cell shape, that showed nodulation, when assessed by hydroponics, showing nodules as early as 3 weeks after reinfection. …”
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28747
In Vitro and In Vivo Characterization of Three Ga- and In-Labeled Peptides for Cholecystokinin Receptor Imaging
Published 2012-09-01“…Cholecystokinin (CCK) receptors are overexpressed in several human tumor types, such as medullary thyroid carcinomas and small cell lung cancers. Several ligands for the CCK2 receptor (CCK2R) have been developed for radionuclide targeting of these tumors. …”
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28748
Clinical value of quantitative echocardiographic features in preterm infants with necrotizing enterocolitis
Published 2025-01-01“…Umbilical vein cannulation, antibiotic duration, total red blood cell infusion, duration of total parenteral and total enteral nutrition, respiratory failure, hemodynamically significant patent ductus arteriosus, anemia, neutropenia, hyperbilirubinemia were significantly higher than those in the control group. …”
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28749
Synthesis of Some Metal Complexes with New Heterocyclic Ligand (5-(((2-(3-(1<i>H</i>-indol-3-yl)acryloyl)phenyl)amino)methylene)-2-thiooxodihydropyrimidine-4,6(1<i>H</i>,5<i>H</i>)...
Published 2025-01-01“…Significant antiproliferative activity was seen in it against human breast cancer (MCF-7) and normal cell lines (MCF-10), as evidenced by the IC50 and selective indices (SI) values. …”
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28750
Implant failure of the Compress prosthesis: a case report
Published 2025-01-01“…Case presentation Case 1 describes a 36 year-old Japanese man who underwent extraarticular tumor resection, Compress arthroplasty, and reconstruction with a gastrocnemius flap after preoperative chemotherapy for a secondary malignant giant cell tumor in the right distal femur. Postoperatively, partial weight-bearing was started at 6 weeks, and full weight-bearing was allowed at 10 weeks. …”
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28751
Characterisation of the antibody-mediated selective pressure driving intra-host evolution of SARS-CoV-2 in prolonged infection.
Published 2024-10-01“…We studied the humoral immune response causing intra-host evolution in a B-cell depleted, haemato-oncologic patient experiencing clinically severe, prolonged SARS-CoV-2 infection with a virus of lineage B.1.177.81. …”
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28752
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28753
An Image of Britain during the Second World War: The films of Humphrey Jennings (1939-1945)
Published 2006-09-01“…La guerre n’était pas encore gagnée, mais la propagande dans le documentaire anglais était bien plus efficace que celle de l’ennemi, et parvenait, en même temps, à toucher toutes les couches de la population.…”
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28754
A Rare Case of Acute Methotrexate Toxicity Leading to Bone Marrow Suppression
Published 2024-01-01“…Complete blood count was suggestive of pancytopenia with hemoglobin of 10.8 g/dL, total white cell count 3.36 (1000/uL) (absolute neutrophil count 490 micro/L), platelets 19,000, serum albumin 3.1 g/dL, ESR elevated at 83 mm/hr, CRP elevated at 86.6 mg/L, and ferritin mildly elevated at 625 ng/mL. …”
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28755
Efficacy of Voriconazole Corneal Intrastromal Injection for the Treatment of Fungal Keratitis
Published 2021-01-01“…The outcome measures consist of the 3-week and 3-month best-corrected visual acuity (BCVA) values and size of infiltrate or scar, time to re-epithelialization, corneal perforation rate and/or therapeutic penetrating keratoplasty (TPK) requirement, the preoperative and post-TCSI corneal endothelial cell density (ECD), and the intraocular pressure (IOP) of the treated eye and the respective contralateral eye. …”
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28756
Gengnianchun Recipe Protects Ovarian Reserve of Rats Treated by 4-Vinylcyclohexene Diepoxide via the AKT Pathway
Published 2020-01-01“…Taken together, these findings suggest that high-dose GNC could protect ovarian reserve against VCD-induced toxicity via the activation of the AKT signaling pathway and reduced cell apoptosis in SD Rats. This effect could either be induced by the increased FSHR signaling or by the nontranscriptional activation of ERβ, which requires further investigation.…”
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28757
Effect of beetroot or beetroot plus vitamin C supplementation on cardiovascular function in patients with coronary artery disease: protocol for a double-blind, placebo-controlled,...
Published 2022-06-01“…Pulse wave velocity, Augmentation Index, heart rate, volume of oxygen (VO2) max/VO2 peak, peak heart rate, blood pressure, interleukin 6 (IL-6), high sensitivity C reactive protein, intercellular adhesion molecule, vascular cell adhesion molecule, lipid profile and anthropometry will be measured at the beginning and end of the intervention.Ethics and dissemination This study was approved by the Ethics Committee of Mashhad University of Medical Sciences (IR.MUMS.MEDICAL.REC.1399.717). …”
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28758
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28759
Multiple ligands simultaneous molecular docking and dynamics approach to study the synergetic inhibitory of curcumin analogs on ErbB4 tyrosine phosphorylation
Published 2024-12-01“…FMM inhibits tyrosine phosphorylation of ErbB4 while 5-FU inhibits cell proliferation. This research aimed to investigate the potential of two compounds, namely (1E,4E)-1,5-bis (4-hydroxyphenyl) penta-1,4-dien-3-one (AC01) and (1E,4E)-1,5-bis (3,4-dihydroxy phenyl) penta-1,4-dien-3-one (AC02), both as individual inhibitors and combination partners with FMM, targeting ErbB4 inhibition. …”
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28760
A green approach to recovering lithium and cobalt from spent lithium-ion batteries using dilute HCl solution mixed with H. sabdariffa flower extract as a leaching agent
Published 2024-01-01“…In this work, an effective process for the recycling of lithium and cobalt from spent cell phone lithium batteries was investigated using HCl solution at low concentrations in combination with H. sabdariffa flower extract. …”
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