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28681
PhyIndBC: Development of a machine learning tool for screening of potential breast cancer inhibitors from phytochemicalsGitHub
Published 2025-06-01“…Thus, in the current study a machine learning (ML) model was created using phytomolecules having inhibitory activity against breast cancer cell lines. Multiple ML techniques viz., k-nearest neighbor (KNN), random forest (RF), support vector machine (SVM), and extreme gradient boosting (XGB) were combined with various molecular fingerprints (MACCS and Morgan2) to develop multiple predictive models. …”
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28682
Effect of NaCI solution concentration, particle size and ratio on viscosity inhibitor of porang flour
Published 2025-01-01“…It aims to analyze those factors effect on viscosity inhibition to support the performance of cavitation bubble formation during the process of breaking cell walls in porang flour. This process was carried out in a factorial complete randomized design (CRD) on all 3 factors with 2 repetitions. …”
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28683
Neuroborreliosis with encephalitis: a broad spectrum of clinical manifestations
Published 2025-02-01“…In addition to central nervous system involvement, all patients exhibited characteristic features of neuroborreliosis like painful meningoradiculitis or peripheral facial palsy. An elevated cell count in cerebrospinal fluid (CSF), positive oligoclonal bands, and blood-CSF barrier dysfunction indicated by an elevated albumin quotient (QAlb) was found in all patients. …”
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28684
Molecular Imaging of Gliomas
Published 2002-10-01“…Before new and potentially more effective treatment strategies, such as gene- and cell-based therapies, can be effectively implemented in the clinical application, certain prerequisites have to be established. …”
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28685
Evaluation and Design of Power Controller of Two-Axis Solar Tracking by PID and FL for a Photovoltaic Module
Published 2020-01-01“…To achieve this, mathematical models of the dynamics of the sun, the solar energy obtained on the Earth’s surface, the two-axis tracking system in its electrical and mechanical parts, and the solar cell are developed and simulated. Two controllers are designed to be evaluated in the solar tracking system, one Proportional-Integral-Derivative and the other by Fuzzy Logic. …”
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28686
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28687
Regulatory mechanism analysis of signal transduction genes during rapeseed (Brassica napus L.) germination under aluminum stress using WGCNA combination with QTL
Published 2025-01-01“…The roles included transcription regulation, stress protein production, redox processes, hormone signaling, cell wall alteration, and calcium-based signal transmission. …”
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28688
The effect of malotilate, a derivative of malotilate and a flavenoid on eicosanoid production in inflammatory bowel disease in rats
Published 1993-01-01“…. < 0.5), based on a seven-scaled scoring system which includes observation of haemorrhage, submucosal oedema, cellular infiltration, goblet cell depletion, loss of architecture, crypt abscesses and serosal involvement, of which every item was subdivided as mild, moderate and severe. …”
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28689
CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy
Published 2019-01-01“…The expression of adipose differentiation-related protein (ADRP), CD36, sterol regulatory element-binding protein 1 (SREBP-1), and peroxisome proliferator-activated receptor α (PPARα) in renal tissue were increased. In in vitro cell experiments, after cultured podocytes were stimulated with leptin, similar to ORG mice, we found aggravated podocyte injury, formatted lipid droplet, increased expression of ADRP and CD36, activated NLRP3 inflammasome, and released IL-1β. …”
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28690
The technology landscape for detection of DNA methylation in cancer liquid biopsies
Published 2025-12-01“…The first methods were established for DNA methylation detection in genomic DNA, while new methods have focused more on compatibility with the emerging interest of cell-free DNA (cfDNA) from liquid biopsies. As DNA methylation detection in cfDNA brings its own challenges, a shift from the gold standard bisulfite conversion towards enzymatic conversion methods can be observed in recent years. …”
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28691
‘DeltaCAN - A new data set of Canadian Arctic and subarctic coastal deltas’
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28692
Un scriitor puţin cunoscut: I. Igiroșianu
Published 2014-12-01“…La perspective d’observation du monde est assez saint-simonienne, celle d’un esprit en incessante combustion, encliné vers la connaissance intérieure de l’homme, avec un grand charme de narrer les grands événements ou les petits faits, dans un style riche, parfois somptueux, de surprendre les pulsations les plus infimes de l’être humaine. …”
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28693
SLC2A5 Correlated with Immune Infiltration: A Candidate Diagnostic and Prognostic Biomarker for Lung Adenocarcinoma
Published 2021-01-01“…Studies based on the TIMER database show a strong correlation between SLC2A5 expression and various immune cell infiltrates and markers. The data analysis in the UALCAN database showed that the decreased promoter methylation level of SLC2A5 in LUAD may lead to the high expression of SLC2A5. …”
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28694
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28695
ET-1 Plasma Levels, Aqueous Flare, and Choroidal Thickness in Patients with Retinitis Pigmentosa
Published 2015-01-01“…Choroidal thickness and aqueous flare were measured, respectively, by using a spectral domain optical coherence tomography and a laser flare-cell meter, whereas plasma samples were obtained from each patient to evaluate ET-1 plasma levels. …”
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28696
Petites mains féminines, vulnérabilité professionnelle et pratiques conjointes de compensation financières dans l’administration publique universitaire au Cameroun
Published 2024-02-01“…On peut dès lors lier la résilience financière des petites mains à un conditionnement socioprofessionnel légitime. Celle qui favorise en tant que positionnement d’action, la compensation de leur revenu par la diversification des activités génératrices de revenus et la mise en place des systèmes d’entraide et de solidarité au sein de l’institution. …”
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28697
Seasonal Pattern of Endo-β-Mannanase Activity During Germination of <i>Jeffersonia dubia</i>, Exhibiting Morphophysiological Dormancy
Published 2025-01-01“…Erosion of the endosperm cell wall was observed in the lateral regions surrounding the embryo, whereas the micropylar endosperm showed no obvious signs of collapse or damage. …”
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28698
Characteristics of COVID-19 clinical trials registered with ClinicalTrials.gov: cross-sectional analysis
Published 2020-09-01“…There are also at least 25 registered trials of azithromycin (n=53), convalescent plasma (n=38), lopinavir/ritonavir (n=30), stem cell treatments (n=29) and tocilizumab (n=25). 142 trials were registered in the first 3 months of 2020, and 488 trials were registered between 1 April and 1 May 2020.Conclusions These findings demonstrate a robust research response to the COVID-19 pandemic, though many of the currently planned and ongoing trials focus on a small number of potential therapies, and many also lack essential design features and power necessary to provide accurate treatment effect estimates.…”
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28699
Effects of Gamma Irradiation on the Properties of Hydroxyapatite-Collagen-Chitosan-Mg-ZnO Scaffolds for Bone Tissue Engineering
Published 2023-01-01“…Moreover, the irradiated and nonirradiated scaffolds were biocompatible and noncytotoxic toward the Vero cell line which ensured their suitability for use in vivo. …”
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28700
Oxidative stress and inflammation in hemodialysis: a comparison of patients with or without advanced nonalcoholic fatty liver disease (NAFLD)
Published 2025-12-01“…There was no significant difference in high-sensitivity C-reactive protein (hs-CRP), and vascular cell adhesion molecule 1 (VCAM-1) between groups. …”
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