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28661
Effects of Enzymatic Liquefaction, Drying Techniques, and Wall Materials on the Physicochemical Properties, Bioactivities, and Morphologies of Zinc-Amaranth (Amaranthus viridis L.)...
Published 2021-01-01“…In this study, zinc- (Zn-) amaranth puree was liquefied with three types of cell wall degrading enzymes (i.e., Viscozyme L, Pectinex Ultra SP-L, and Rapidase PAC) with varying concentrations (0–3% v/w) and incubation time (0.5–24 h) at pH 5 and 45°C before the drying process. …”
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28662
In vitro and in silico insights into antimicrobial and anticancer activities of novel imidazo[2,1-b][1,3,4]thiadiazoles
Published 2024-12-01“…The anticancer activity of the compounds against MCF-7 cell lines showed promising activity, where three derivatives, 3a, 3c and 3d exhibited better inhibition than the standard, cisplatin. …”
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28663
Exposure of Mycobacteriodes abscessus clones to mucin affects bacterial phenotype
Published 2025-01-01“…Bacteria clones arrested growth, produced different biofilms compositions, increased the resistance to antibiotics, and some changed the cell wall surfaces. These observations have direct implications in virulence and the response of the pathogen to treatment.…”
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28664
Evaluation of the Presentation of Newly Diagnosed Type 1 Diabetes Mellitus in Children During and After the COVID-19 Pandemic
Published 2024-04-01“…The rate of male patients diagnosed during the pandemic period was significantly higher (56%, 36%, respectively, p=0.007). Anti-islet Cell antibody (ICA) positivity was statistically significantly higher in those diagnosed during the pandemic period. (52.6%, 18.6%, respectively, p<0.001). …”
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28665
HUBUNGAN TINGKAT KEPATUHAN KONSUMSI OBAT ANTI RETRO VIRAL (ARV) PADA PASIEN HIV DENGAN KEJADIAN INFEKSI PROTOZOA USUS DI RSUP DR M DJAMIL PADANG
Published 2017-10-01“…Ketidak patuhan konsumsi ARV meningkatkan resiko infeksi protozoa usus pada pasien HIV/AIDS dengan CD 4 + T cell<200 sel/μl. Tujuan penelitian ini adalah untuk menentukan hubungan antara tingkat kepatuhan konsumsi ARV dengan kejadian infeksi protozoa usus di RSUP Dr.M.Djamil Padang. …”
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28666
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28667
Thyrotoxicosis due to Gestational Trophoblastic Disease: Unmet Needs in the Management of Gestational Thyrotoxicosis
Published 2024-01-01“…Molar pregnancy stands out as a pathological condition characterized by abnormal trophoblastic cell growth, which can manifest in benign or malignant forms, and is diagnosed with a disproportionate elevation of β-hCG (beta-human chorionic gonadotrophin) and specific features on ultrasonography including absent sac and large multicystic or honeycomb appearance. …”
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28668
Development and validation of a machine learning-based prediction model for hepatorenal syndrome in liver cirrhosis patients using MIMIC-IV and eICU databases
Published 2025-01-01“…The final predictive model, based on five key variables—spontaneous bacterial peritonitis, red blood cell count, creatinine, activated partial thromboplastin time, and total bilirubin—showed excellent discrimination, with AUCs of 0.832 (95% CI 0.8069–0.8563) in the training set and 0.8415 (95% CI 0.8042–0.8789) in the validation set. …”
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28669
Effects of different Lys/Met ratios on the antioxidant capacity, tissue morphology, and fatty acid composition of subcutaneous fat in Tibetan sheep on low-protein diets: a lipidomi...
Published 2025-01-01“…The expression of genes associated with adipogenesis, antioxidant capacity, and fatty acid metabolism was also examined.ResultsThe results indicated that the 1:1 Lys/Met group exhibited significantly higher antioxidant capacity (glutathione peroxidase, GSH-Px), with more orderly adipocyte arrangement, uniform cell size, and a general increase in unsaturated fatty acid levels. …”
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28670
Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient
Published 2023-01-01“…The patient received intravenous proton pump inhibitors and a packed red blood cell transfusion. Genetic analysis revealed that the patient was a carrier of CYP2C9∗3 and CYP2C8∗3 variant alleles, indicating that the patient is a poor metabolizer for both enzymes. …”
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28671
APPLICATION OF REFRIGERATED AND FROZEN SORGHUM MALT SLURRIES IN THE PRESERVATION OF STARTER CULTURES FOR OBUSHERA FROM UGANDA
Published 2020-12-01“…Viability of <em>Saccharomyces cerevisiae </em>and <em>Lactobacillus plantarum</em><em> </em>was determined by cell counts after surface plating and pour plating, respectively. …”
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28672
Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes.
Published 2024-01-01“…Characteristic signature genes were used to create novel diagnostic models and construct competing endogenous RNA (ceRNA) regulatory network for PD, which were further verified by in vitro experiments and single-cell RNA sequencing (scRNA-seq).<h4>Results</h4>A total of 453 DEGs were identified and 11 FRGs were selected. …”
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28673
Preparation and characterisation of ciprofloxacin‐loaded silver nanoparticles for drug delivery
Published 2022-05-01“…In addition, the toxicity of AgNPs and Cipro‐AgNPs nanocomposites was evaluated using normal (3T3) cell line. The present work suggests that Cipro‐AgNPs are suitable for drug delivery.…”
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28674
Approaching maximum resolution in structured illumination microscopy via accurate noise modeling
Published 2025-01-01“…B-SIM enables unsupervised, quantitative, physically accurate reconstruction without the need for labeled training data, democratizing high-quality SIM reconstruction and expands the capabilities of live-cell SIM to lower SNR, potentially revealing biological features in previously inaccessible regimes.…”
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28675
Enhancing Cervical Cancer Classification: Through a Hybrid Deep Learning Approach Integrating DenseNet201 and InceptionV3
Published 2025-01-01“…Visualization tools, including high-resolution confusion matrices and ROC curves, further demonstrate the hybrid model’s capability to differentiate between cervical cancer cell classes accurately. Comparative analyses validate the model’s superior performance and its potential as a dependable tool for clinical implementation. …”
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28676
Clinical characteristics of anti-myelin oligodendrocyte glycoprotein antibody among aquaporin-4 negative neuromyelitis optica spectrum disorders in Egyptian patients
Published 2025-01-01“…They were screened for anti-MOG antibodies by the indirect immunofluorescence cell-based assay. Of all included patients, only 7.5% (n = 3) were positive for anti-MOG antibodies and had significantly higher disability scores than seronegative patients (p = 0.021). …”
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28677
An UPLC-MS/MS Method for Determination of Osimertinib in Rat Plasma: Application to Investigating the Effect of Ginsenoside Rg3 on the Pharmacokinetics of Osimertinib
Published 2020-01-01“…Osimertinib is a novel oral, potent, and irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) for treatment of advanced T790M mutation-positive advanced non-small cell lung cancer, which is commonly combined with ginsenoside Rg3 in clinic to enhance the efficacy and minimize adverse reactions. …”
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28678
Overwhelming Pulmonary Infection after a Tobogganing Accident
Published 2005-01-01“…Laboratory results showed a white blood cell count of 40×109/L with a left shift. Chest radiography showed a left pleural effusion. …”
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28679
Bipolar membrane/hydrophobic gas permeable membrane electrochemical systems for highly efficient removal of ammonium nitrogen in wastewater
Published 2024-02-01“…To address the pH dependency in the electrochemical oxidation and separation of ammonia nitrogen, we leveraged the advantages of a bipolar membrane (BPM) that stably generates H+/OH- in the electrolytic cell. Consequently, we proposed a bipolar membrane/hydrophobic gas permeable membrane-electrochemical system (BPM/GPM-EC) that demonstrated remarkable performance in removing ammonia nitrogen from wastewater. …”
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28680
Clinical Features, Treatment, and Surveillance of Hyperparathyroidism-Jaw Tumor Syndrome: An Up-to-Date and Review of the Literature
Published 2019-01-01“…HPT-JT syndrome is caused by germline mutations of the cell division cycle 73 (CDC73) gene that encodes the parafibromin, a 531-amino acid protein with antiproliferative activity. …”
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