Renal Transplantation in Hepatitis C Positive Patients: A Single Centre Experience by P. R. Shah, A. V. Vanikar, M. R. Gumber, H. V. Patel, V. B. Kute, S. M. Godara, H. L. Trivedi

“…TIP consisted of 1 donor-specific transfusion, peripheral blood stem cell infusion, portal infusion of bone marrow, and target-specific irradiation. …”
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Neurofilament light chain levels in neuronal surface antibody-associated autoimmune encephalitis: a systematic review and meta-analysis by Qi-Lun Lai, Meng-Ting Cai, Er-Chuang Li, Gao-Li Fang, Chun-Hong Shen, Yong-Feng Xu, Song Qiao, Jia-Jia Wang, Qin-Jie Weng, Yin-Xi Zhang

“…Abstract Background Neuronal surface antibody-associated autoimmune encephalitis (NSAE) is a group of neuro-inflammatory disorders that is mediated by autoantibodies against the cell-surface and synaptic antigens. Studies have explored the role of neurofilament light chain (NfL) in NSAE and provided inconsistent data. …”
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Deciphering the Molecular Mechanism of Peracetic Acid Response in Listeria monocytogenes by Marianna Arvaniti, Ahmed Gaballa, Renato H. Orsi, Panagiotis Skandamis, Martin Wiedmann

“…Hence, this study identified key elements involved in the primary response of L. monocytogenes to oxidative stress caused by PAA, including the expression of the peroxide detoxification system and fine-tuning the levels of redox-active metals in the cell. The investigation of the molecular mechanism of PAA response in L. monocytogenes is of utmost importance for the food industry, as residual PAA can lead to stress tolerance in pathogens.…”
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Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution by Florian Dunker-Seidler, Kathrin Breunig, Magdalena Haubner, Florian Sonntag, Markus Hörer, Rebecca C. Feiner

“…Our data highlight a high vector batch quality with low plasmid-derived and host cell DNA impurities of random origin, critical for mitigating associated safety risks. …”
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Uptake kinetics and distribution of flupyrimin by rice (Oryza sativa L.): Effects of subcellular fractionation and soil factors by Xugen Shi, Min Wang, Zhenyu Jiang, Ruqiang Cui, Baotong Li, Xianpeng Zhang, Lianhu Zhang, Duantao Cao

“…The hydroponic experiment indicated that flupyrimin was easily taken up by rice roots via a symplastic passive diffusion process and was mainly distributed in the cell soluble fractions (50.6 %－88.0 %). Compared with transportation from the roots to the stems, flupyrimin was ultimately transported from the stems to the leaves with a greater translocation factor (TF) (TFLeave/Stem = 27.8 > TFStem/Root = 3.1). …”
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Liangxue Tongyu Prescription exerts neuroprotection by regulating the microbiota-gut-brain axis of rats with acute intracerebral hemorrhage by Yingying Sun, Dandan Zhou, Anlan Liu, Yu Zhou, Yang Zhao, Yuan Yuan, Weifeng Guo, Jianxiang Li

“…Analysis via western blot, quantitative real-time PCR, immunohistochemistry (IHC) and tunel staining indicated that LTP upregulated the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor(NGF) and reduced neuronal cell apoptosis. Additionally, 16S rDNA sequencing revealed that LTP mitigated dysbiosis of intestinal microbiota in AICH rats. …”
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Targeting tRNA‐Derived Non‐Coding RNA Alleviates Diabetes‐Induced Visual Impairment through Protecting Retinal Neurovascular Unit by Jin Yao, Wen Yao, Jun‐Ya Zhu, Yan Liu, Jin‐Hong Liu, Yu‐Ke Ji, Xi‐Shen Ni, Wan Mu, Biao Yan

“…In this study, the up‐regulation of a tRNA‐derived stress‐induced RNA, 5′tiRNA‐His‐GTG, in response to diabetic stress is revealed. 5′tiRNA‐His‐GTG directly regulates Müller glia action and indirectly alters endothelial angiogenic effects and retinal ganglion cell (RGC) survival in vitro. Downregulation of 5′tiRNA‐His‐GTG alleviates diabetes‐induced retinal neurovascular dysfunction, characterized by reduced retinal vascular dysfunction, decreased retinal neurodegeneration, and improved visually‐guided behaviors in vivo. …”
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Meat analogues: The relationship between mechanical anisotropy, macrostructure, and microstructure by Miek Schlangen, Iris van der Doef, Atze Jan van der Goot, Mathias P. Clausen, Thomas E. Kodger

“…Two distinct meat analogue product sets are produced with shear cell technology varying in formulations and processing conditions to obtain a wide range of product structures: one based on mung bean protein-rich fractions and the other based on combinations of soy protein isolate and pectin. …”
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Comparative Effectiveness of Darunavir 1,200 mg Daily and Approved Dosing Strategies for Protease Inhibitor-Experienced Patients by James M. Mikula, Chiu-Bin Hsiao, Joshua R. Sawyer, Qing Ma, Gene D. Morse

“…Data collection from inception of DRV use in August 2006 through March 2012 included patient demographics, viral loads, CD4+ cell counts, and resistance test results. The primary outcome of virologic suppression was defined as <50 copies/mL at 24 weeks. …”
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Andrographolide Protects against HG-Induced Inflammation, Apoptosis, Migration, and Impairment of Angiogenesis via PI3K/AKT-eNOS Signalling in HUVECs by Ming-Xia Duan, Heng Zhou, Qing-Qing Wu, Chen Liu, Yang Xiao, Wei Deng, Qi-Zhu Tang

“…We discovered that Andr inhibited the inflammatory response (IL-1β, IL-6, and TNFα), decreased the apoptosis ratio and cell migration, and promoted tube formation in response to HG stimulation. …”
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Identification of fatty acid anabolism patterns to predict prognosis and immunotherapy response in gastric cancer by Weijie Sun, Yanhong Xia, Feifan Jin, Jinghao Cao, Gaoping Wu, Keyi Li, Yanhua Yu, Yunyi Wu, Gaoqi Ye, Ke Xu, Dengpan Liu, Weidong Jin

“…Through consistent clustering and functional enrichment analysis, three distinct fatty acid anabolism clusters and three gene subtypes were identified to participate in different biological pathways, and correlated with the characteristics of immune cell infiltration and clinical prognosis. Importantly, a distinctive FA-score was constructed through the principal component analysis to quantify the characteristics of fatty acid anabolism in each GC patient. …”
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Reassessing the roles of oxidative DNA base lesion 8-oxoGua and repair enzyme OGG1 in tumorigenesis by Jing Wang, Chunshuang Li, Jinling Han, Yaoyao Xue, Xu Zheng, Ruoxi Wang, Zsolt Radak, Yusaku Nakabeppu, Istvan Boldogh, Xueqing Ba

“…Substrate recognition and/or excision by OGG1 can cause DNA conformation changes, affect chromatin modifications, thereby modulating the transcription of genes involved in a variety of cellular processes, including inflammation, cell proliferation, differentiation, and apoptosis. …”
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Ethanolic extract of black soldier fly (Hermetia illucens L.) larvae for wound healing in mice (Mus musculus L.) by Darman Agung Sandakila, Gracetia Devita Hadi, Riska Gultom, Seni Samalele, Rudy Agung Nugroho

“…The highest total DNA content was observed in the 20% BSFL group (42.25 ± 7.45 µg/mL), indicating enhanced cell proliferation. Gas Chromatography Mass Spectrophotometry analysis revealed high lauric acid content (44.27%) in the extract, known for its antibacterial properties. …”
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Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…**Background:** Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can be a lifesaving treatment for hematologic malignancies, but acute graft-versus-host-disease (aGVHD) is a potentially deadly adverse effect experienced by up to half of allo-HSCT recipients. …”
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Genetic Dissection of Sympatric Populations of Brown Planthopper, Nilaparvata lugens (Stål), Using DALP-PCR Molecular Markers by M. A. Latif, M. Y. Rafii, M. S. Mazid, M. E. Ali, F. Ahmed, M. Y. Omar, S. G. Tan

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Impact of stain variation and color normalization for prognostic predictions in pathology by Siyu Lin, Haowen Zhou, Mark Watson, Ramaswamy Govindan, Richard J. Cote, Changhuei Yang

“…This study used sample data from a previously reported DNN that was able to identify patients with early-stage non-small cell lung cancer (NSCLC) whose tumors did and did not metastasize, with high accuracy, based on training and then testing of digital images from H&E stained primary tumor tissue sections processed at the same time. …”
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Combined Phacoemulsification and Goniosynechialysis under an Endoscope for Chronic Primary Angle-Closure Glaucoma by Li Nie, Weihua Pan, Aiwu Fang, Zhangliang Li, Zhenbin Qian, Lin Fu, Yau Kei Chan

“…Other measurements included supraciliochoroidal fluid measured by anterior segment optical coherence tomography, corneal endothelial cell density (ECD), and peripheral anterior synechia (PAS). …”
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Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis by Xuefeng Liu, Zhiqiang Chen, Meng Yu, Wei Zhou, Xuting Zhi, Tao Li

“…Simultaneous approaches significantly promoted 1-, 3-, and 5-year disease-free survival (DFS) rates and overall survival (OS) rates, prolonged operation time, aggravated intraoperative blood loss, increased white blood cell (WBC) and platelet (PLT) counts at POD 7, and lowered total bilirubin (T-Bil) contents at POD 1 and 7. …”
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Development and use of indirect liquid-phase ELISA test system for detection of PRRS virus antigen during in-process control of raw materials intended for vaccine production by Ye. P. Baborenko, O. P. Byadovskaya, D. A. Biryuchenkov, A. V. Konstantinov, R. V. Yashin

“…Results of development of the test system based on indirect liquid-phase enzyme-linked immunosorbent assay (ELISA) for PRRS virus antigen detection and activity testing in infectious and inactivated virus-containing cell cultures at intermediate stages of the vaccine production process are described in the paper. …”
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Evaluating the influence of trypanosomiasis on murine model using Corchorus olitorius leaf extract as a trypanocidal agent by Madaki Fatima M., Adamu Kabiru Y., Ogunrombi Clinton D., Sakariyau Waheed A., Yunusa Ibrahim O.

“…Furthermore, the 400 mg/kg dose notably increased packed cell volume and body weight in infected rats. Moreover, there were no significant discrepancies in numerous hematological parameters between the infected treated with diminazene aceturate and the extract's 400 mg/kg body weight. …”
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