Albino lethal 13, a chloroplast‐imported protein required for chloroplast development in rice by Xiaoqiong Guo, Chunli Wang, Qian Zhu, Wenhua Dongchen, Xiaoling Zhang, Wei Li, Hui Zhang, Cui Zhang, Zar Ni Naing Nant Nyein, Mengting Li, Lijuan Chen, Dongsun Lee

“…This gene was located in the chloroplast and exhibited constitutive expression in various tissues, particularly in green tissues and regions of active cell growth. Our study's findings reveal that RNAi‐mediated knockdown of OsAL13 led to a pronounced albino phenotype, reduced chlorophyll and carotenoid contents, a vesicle chloroplast structure, and a decrease in the expression of chloroplast‐associated genes. …”
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Transcriptome-wide identification and characterization of WUSCHEL-related homeobox (WOX) gene family in Pinus yunnanensis by Junfei Xu, Zhaoliu Hu, Sili Chen, Junrong Tang, Lin Chen, Peizhen Chen, Nianhui Cai, Yulan Xu

“…Abstract WUSCHEL-related homeobox (WOX), a specific gene family in plants, plays a critical role during stem cell regulation, plant regeneration and upgrowth. …”
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Scutellarin Attenuates Hypertension-Induced Expression of Brain Toll-Like Receptor 4/Nuclear Factor Kappa B by Xingyong Chen, Xiaogeng Shi, Xu Zhang, Huixin Lei, Simei Long, Huanxing Su, Zhong Pei, Ruxun Huang

“…Furthermore, expression of the antiapoptotic protein, myeloid cell leukemia-1 (Mcl1), was decreased, and the pro-apoptotic proteins, Bax and cleavedcaspase-3 p17 were increased in combined cerebral cortical/striatal soluble lysates. …”
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Baicalin: a potential therapeutic agent for acute kidney injury and renal fibrosis by Xiaoming Li, Xiaoming Li, Rui Xu, Rui Xu, Dan Zhang, Ji Cai, Ji Cai, He Zhou, He Zhou, Tao Song, Tao Song, Xianyao Wang, Xianyao Wang, Qinghong Kong, Liujin Li, Zhaohui Liu, Zhixu He, Zhengzhen Tang, Jun Tan, Jidong Zhang, Jidong Zhang, Jidong Zhang

“…Baicalin’s therapeutic effects are achieved through various pathways, including antioxidant, anti-inflammatory, antifibrosis, and regulation of apoptosis and cell proliferation. Besides, we also hope this review may give some enlightenment for treating AKI and renal fibrosis in clinical practice.…”
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Autoimmune Hepatitis in Brazilian Children: IgE and Genetic Polymorphisms in Associated Genes by Léa Campos de Oliveira, Anna Carla Goldberg, Maria Lucia Carnevale Marin, Karina Rosa Schneidwind, Amanda Farage Frade, Jorge Kalil, Irene Kasue Miura, Renata Pereira Sustovich Pugliese, Vera Lucia Baggio Danesi, Gilda Porta

“…Pediatric autoimmune hepatitis (AIH) patients present hypergammaglobulinemia, periportal CD8+ cytotoxic T cell infiltration, and cirrhosis. Autoantibody profile defines AIH types 1 and 2 in addition to strong association with HLA-DRB1. …”
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A 3D semantic segmentation network for accurate neuronal soma segmentation by Li Ma, Qi Zhong, Yezi Wang, Xiaoquan Yang, Qian Du

“…However, the fine structure, such as boundaries, small-volume neuronal somata and fibers, are commonly present in cell images, which pose a challenge for accurate segmentation. …”
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A Study of the Corrosion Behavior of AHSS Complex-Phase CP 780 Employing an Electrochemical Noise Technique Analyzed by Different Methods by Maria Lara-Banda, Facundo Almeraya-Calderón, Jesús Manuel Jáquez-Muñoz, Demetrio Nieves-Mendoza, Miguel Angel Baltazar-Zamora, Javier Olguín-Coca, Francisco Estupiñan-Lopez, Jose Cabral Miramontes, Griselda Santiago-Hurtado, Citlalli Gaona-Tiburcio

“…The electrochemical noise technique was made with a conventional three-electrode cell, using a saturated calomel as a reference electrode. …”
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EfficientNet-B0 outperforms other CNNs in image-based five-class embryo grading: a comparative analysis by Vincent Jaehyun Shim, Hosup Shim, Sangho Roh

“…Gradient-weighted Class Activation Mapping was used to interpret the models’ decision-making processes, revealing that the most successful models predominantly focused on the inner cell mass, a critical determinant of embryo quality. …”
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Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data by Jie Ma, Chuanxi Chen, Andreas S. Barth, Chris Cheadle, Xiangdong Guan, Li Gao

“…In contrast, pathways related to “Ribosome”, “Spliceosome” and “Cell adhesion molecules” were found to be downregulated, along with known pathways for immune dysfunction. …”
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Antianemic Treatment of Cancer Patients in German Routine Practice: Data from a Prospective Cohort Study—The Tumor Anemia Registry by Tilman Steinmetz, Jan Schröder, Margarete Plath, Hartmut Link, Michèle Vogt, Melanie Frank, Norbert Marschner

“…Median age was 67 years; 48% were male. Red blood cell transfusions (RBCTx) were given to 59% of all patients and to 55% of the patients with Hb ≥8 g/dL on day 1 of the observation period (day 1 treatment). …”
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Use of Hybrid Flame Retardants in Chemically Foamed rPET Blends by Veronika Anna Szabó, Sándor Kálmán Jakab, András Kovács, Tamara Zsuzsanna Böcz, Gábor Dogossy

“…The addition of MPP reduced the porosity in many cases, while preventing cell coalescence. Our results prove that the hybrid flame retardant agent frameworks efficiently increase the flame retardancy of rPET foams, facilitating their application in industrial sectors such as the aerospace, packaging, renewable energy, and automotive industries to realize sustainability goals. …”
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Multiepitope Subunit Vaccine Design against COVID-19 Based on the Spike Protein of SARS-CoV-2: An In Silico Analysis by Hamza Arshad Dar, Yasir Waheed, Muzammil Hasan Najmi, Saba Ismail, Helal F. Hetta, Amjad Ali, Khalid Muhammad

“…In silico epitope prioritization shortlisted six HLA I epitopes and six B-cell-derived HLA II epitopes. These high-ranked epitopes were all connected to each other via flexible GPGPG linkers, and at the N-terminus side, the sequence of Cholera Toxin β subunit was attached via an EAAAK linker. …”
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Metabolomics and transcriptomics analyses revealed overexpression of TaMGD enhances wheat plant heat stress resistance through multiple responses by Dongyun Ma, Haizhou Hu, Jianchao Feng, Beiming Xu, Chenyang Du, Yang Yang, Yingxin Xie, Chenyang Wang

“…Our findings demonstrate that overexpression of TaMGD in wheat affects multiple metabolic pathways, including photosynthesis, carbon, and amino acid metabolism, in reply to high-temperature stress through the modification of cell membrane lipid content, fatty acid unsaturation and other factors.…”
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In Vitro Cadmium-Induced Alterations in Growth and Oxidative Metabolism of Upland Cotton (Gossypium hirsutum L.) by M. K. Daud, Lei Mei, Ullah Najeeb, Muhammad Azim Khan, Farah Deeba, Irum Raza, Aliya Batool, S. J. Zhu

“…At 1000 μM Cd, mean growth values were lower than their respective control. The cell protein contents decreased only after 7-day and 14-day stress treatment. …”
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Self-healable and pH-responsive spermidine/ferrous ion complexed hydrogel Co-loaded with CA inhibitor and glucose oxidase for combined cancer immunotherapy through triple ferroptos... by Tianqi Nie, Yifei Fang, Ruhe Zhang, Yishui Cai, Xiaobo Wang, Yuenong Jiao, Jun Wu

“…Investigation on cancer cell lines (MOC-1) demonstrated ACZ/GOx@SPM-HA Gel may induce cellular oxidative stress and mitochondrial dysfunction through disrupting the cellular homeostasis. …”
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Association of Cutaneous Immune-related Adverse Events with Overall Survival and Progression-free Survival in Oncology Patients Receiving Immune Checkpoint Inhibitors: A Prospectiv... by Gloria Juan-Carpena, Natividad Martínez Banaclocha, Juan Carlos Palazón Cabanes, Maria Niveiro-de Jaime, Isabel Betlloch Mas, Mar Blanes-Martínez

“…Most participants (56.6%) were diagnosed with non-small cell lung cancer (NSCLC). Mortality and progression rates were lower in patients with vs without cirAEs (p < 0.0001). …”
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Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism by Susan Lin, Aravind R Gade, Hong-Gang Wang, James E Niemeyer, Allison Galante, Isabella DiStefano, Patrick Towers, Jorge Nunez, Maiko Matsui, Theodore H Schwartz, Anjali Rajadhyaksha, Geoffrey S Pitt

“…To overcome these challenges, we generated a set of novel cell-type-specific conditional knockout mice. Interneuron-targeted deletion of Fgf13 led to perinatal mortality associated with extensive seizures and impaired the hippocampal inhibitory/excitatory balance while excitatory neuron-targeted deletion of Fgf13 caused no detectable seizures and no survival deficits. …”
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Association between Optical Coherence Tomography Measurements and Clinical Parameters in Idiopathic Intracranial Hypertension by Priscilla Fernandes Nogueira, Gustavo Coelho Caiado, Carolina P. B. Gracitelli, Fernando Meister Martins, Felipe Chaves Duarte Barros, Sandro Luis De Andrade Matas, Sérgio Henrique Teixeira, Luciana da Cruz Noia, Danilo Andriatti Paulo

“…Correlations between ganglion cell complex (GCC) thickness and retinal nerve fiber layer (RNFL) thickness, as measured by SD-OCT, and clinical parameters were assessed using generalized estimating equations. …”
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The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer by Si Chen, Caihong Yao, Na Tian, Chunying Zhang, Yuemei Chen, Xuting Wang, Yue Jiang, Tonghao Zhang, Tingting Zeng, Yali Song

“…Notable impacts on the immune microenvironment include changes in immune cell function and the regulation of immune checkpoints, offering insights into potential targets for cancer immunotherapy. …”
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Central Venous-to-Arterial CO2 Gap Is a Useful Parameter in Monitoring Hypovolemia-Caused Altered Oxygen Balance: Animal Study by Szilvia Kocsi, Gabor Demeter, Daniel Erces, Eniko Nagy, Jozsef Kaszaki, Zsolt Molnar

“…Microcirculatory parameters, capillary perfusion rate and red blood cell velocity, decreased significantly over time. …”
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