Pediatric and adolescent chronic myeloid leukemia: A follow-up study in Western India by Sangita A. Vanik, Dhaval Jetly, Biren Parikh, Karthik Dhandapani, Rukmini Bezbaruah

“…The median hemoglobin was 8.4 g/dL and 63.6% of the cases showed white blood cell (WBC) counts >250,000/μL. The average follow-up was 21 months. …”
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A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer by Ruyue Chen, Zengwu Yao, Lixin Jiang, Jinchen Hu

“…Results Consensus clustering based on 17 GARG identified two patient subgroups, C1 and C2, exhibiting differential survival, immune scores, and immune cell infiltration. We developed a GARRS using Cox-Lasso regression analysis, accurately stratifying patients into high- and low-risk groups. …”
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Reducing postoperative blood product usage and costs in cardiothoracic surgery: the implementation of a multispecialty perioperative care model incorporating a haemostasis checklis... by Krishnaswamy Sundararajan, Peter Hibbert, Christopher Daniel Smith, Adrian De Luca

“…Following intervention, a 60% reduction in blood product use within the first 12 hours of cardiopulmonary bypass was observed. Red cell, cryoprecipitate and fresh frozen plasma usage were particularly reduced with 57%, 47% and 72% reductions, respectively, following intervention and similar results were maintained on repeat audit 1-year postintervention, with on average 84 fewer blood products used per 100 patients. …”
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Challenges in Diagnosis and Management of Altered Mental Status in the Setting of Urosepsis and Hydrocephalus Secondary to an Occlusive Cyst of the Fourth Ventricle: A Case Report by Matthew Van Ligten, Miles Hudson, Jonathon J. Parker, Wayne A. Martini

“…The acute management involved empirical antibiotic therapy for associated sepsis, followed by the placement of an external ventricular drain for cerebrospinal fluid diversion and sampling, including cytology and cell counts, given the concern for tonsillar herniation with a lumbar puncture. …”
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Regulating Immune Responses Induced by PEGylated Messenger RNA–Lipid Nanoparticle Vaccine by Hyein Jo, Jaewhoon Jeoung, Wonho Kim, Dooil Jeoung

“…After an mRNA-LNP vaccine enters a cell via an endosome, mRNA is translated into an antigen, which can activate adaptive immunity. mRNAs can bind to various pattern recognition receptors (PRRs), including toll-like receptors (TLRs), and increase the production of inflammatory cytokines. …”
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Evaluation of Association of Oral Bacterial Profile with HBV and HCV Infection and T Lymphocyte Level in HIV-Positive Patients by Fatemeh Lavaee, Farzan Modarresi, Samira Amookhteh, Mohammad Amin Amiri

“…Demographic data including sex, ethnicity, CD4+ T cell, and T lymphocyte counts were collected from their medical records. …”
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The Relationship between Visual-Evoked Potential and Optic Coherence Tomography and Clinical Findings in Parkinson Patients by Zeynep Tuncer, Gamze Dereli Can, Hava Dönmez Keklikoğlu, Fatma Ayşen Eren, Fatma Yülek, Orhan Deniz

“…RNFL (retinal nerve fiber layer) was measured in temporal, superior, nasal, and inferior quadrants. Ganglion cell complex (GCC) was evaluated in the superior and inferior quadrants. …”
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ANTIMICROBIAL ACTIVITY AND MECHANICAL PROPERTIES OF EDIBLE FILM ENRICHED WITH FINGERED CITRON WATER EXTRACT AND PROBIOTIC by HILAL TASBASI, MELTEM ASAN-OZUSAGLAM

“…Also, it was determined that FCW extract prepared at 50 and 100 mg·mL-1 concentration had an inhibitory effect against E. coli O157:H7 at 0, 24 and 48th hours by viable cell count. Then, the antimicrobial activity of the prepared films was evaluated and the highest and lowest inhibition zone diameters against E. coli O157:H7 (12.85 mm) and Streptococcus agalactiae Pas. …”
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Glutathione S-transferase polymorphism in ethnic groups living in Eastern Siberia by E. V. Belyaeva, O. A. Yershova, T. A. Astahova, O. V. Bugun

“…The role of glutathione S-transferase for the life of the cell and the entire organism is related to their participation in the processes of detoxification of xenobiotics and antioxidant protection. …”
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Butein Inhibits Oxidative Stress Injury in Rats with Chronic Heart Failure via ERK/Nrf2 Signaling by Peng Liu, Quanli Pan

“…Hematoxylin and eosin (H&E) staining was used to observe the myocardial cell morphology. The effect of butein on the extracellular signal-regulated kinase (ERK)/nuclear factor-E2 p45-related factor (Nrf2) signaling was confirmed by Western blot analysis. …”
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Golden Tandem of Photothermal Ablation and Simultaneous Anti-Inflammation in One Nanoparticle for Activated Macrophage-Targeted Atherosclerosis Treatment by Lu Y, Wang Y, Li Y, Li Y, Jiang YW, Li J

“…The preparation and characterization of GSNPD, their cellular toxicity, photothermal conversion and targeted ablation efficiency, anti-inflammation and ROS scavenging effect, as well as the inhibition of foam cell formation were studied in vitro.Results: The experimental results showed that the fabricated GSNPD NPs displayed positive effects on anti-atherosclerosis by pro-inflammatory macrophages ablation, NO production and ROS scavenging.Discussion: GSNPD NPs were designed to effectively and accurately ablate pro-inflammatory macrophages by recognizing and targeting to SR-A overexpressed on the activated macrophages of arterial plaques via PTT, and simultaneous inhibit the PTT-induced inflammation through the laser-activated NO release in situ. …”
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The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study by Keiichiro Suminaga, Takashi Nomizo, Hironori Yoshida, Hiroaki Ozasa

“…Method Patients treated with immune checkpoint inhibitor monotherapy for non-small cell lung cancer at Kyoto University Hospital until January 2023, with TPS data and biological specimens available for SNP measurement, were eligible for this study. …”
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Lessons from SARS-CoV, MERS-CoV, and SARS-CoV-2 Infections: What We Know So Far by Radi Taha Alsafi

“…Therefore, this review summarizes the state-of-the-art information and compares the similarities and dissimilarities between SARS-CoV, MERS-CoV, and SARS-CoV-2, in terms of their evolution trait, genome organization, host cell entry mechanisms, tissue infectivity tropisms, transmission routes and contagiousness, and the clinical characteristics, laboratory features, and immunological abnormalities of their related illnesses. …”
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A re-look at the modified Ryan regression scoring system in esophageal cancer—validation of prognostic significance and comparison with other less commonly used systems by Paromita Roy, Rupanita Biswal, Sayali N. Honap, Robin Thambudorai, Tapesh Bhattacharyya, Indranil Mallick

“…Results: Our series includes 93 patients with predominantly mid-esophageal squamous cell carcinoma. Complete pathological response (pCR) was noted in 47% (44/93) patients. …”
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ABO isoagglutinin titers in group “O” blood donors by Sadhana Mangwana, Shashi Kumar, Vivek Gangwar

“…Immunoglobulin (Ig) M antibody titers were measured by hemagglutination and IgG titers by solid-phase red cell adherence. Antibody titers ≥128 for IgG and ≥64 for IgM were considered “high titers.” …”
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Cholestatic Hepatocellular Injury with Azathioprine: A Case Report and Review of the Mechanisms of Hepatotoxicity by Joseph Romagnuolo, DC Sadowski, E Lalor, L Jewell, ABR Thomson

“…The cases reported to date can be grouped into three syndromes: hypersensitivity; idiosyncratic cholestatic reaction; and presumed endothelial cell injury with resultant raised portal pressures, veno-occlusive disease or peliosis hepatis. …”
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Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking by Maheswata Sahoo, Lingaraja Jena, Surya Narayan Rath, Satish Kumar

“…It is responsible for sialic acid cleavage from glycans of the infected cell. We employed amino acid sequence of H1N1 NA to predict the tertiary structure using Phyre2 server and validated using ProCheck, ProSA, ProQ, and ERRAT server. …”
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Spectral Investigation and In Vitro Antibacterial Evaluation of NiII and CuII Complexes of Schiff Base Derived from Amoxicillin and α-Formylthiophene (αft) by Narendra Kumar Chaudhary, Parashuram Mishra

“…The structure optimization by molecular mechanics (MM) force field calculation through ArgusLab 4.0.1 version software also supports the concerned geometry of the complexes. The cell dimensions as suggested by XRPD study, a (6.753 Å), b (13.904 Å), c (20.122 Å), α (142.76°), β (106.580°), and γ (72.4343°) for CuII and a (24.2547 Å), b (6.6371 Å), c (5.5047 Å) (α = β = γ = 90°) for NiII complexes, are in good agreement with their triclinic and orthorhombic crystal systems. …”
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Evaluation of Antidiabetic Properties of the Leaves Extract of Ficus vallis-choudae Delile in a Model of Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin by Kilenma Kolefer, David Miaffo, Roger Ponka

“…In addition, it dramatically reduced body mass, body mass index (BMI), atherogenic index (AI), coronary heart risk index (CRI), and abdominal fat and increased homeostatic model assessment of β-cell function (HOMA-β), high-density lipoprotein cholesterol (HDL-c) levels, and cardioprotective index (CI). …”
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Prevalence of Esophageal Eosinophilia, Eosinophilic Esophagitis, and Lymphocytic Gastritis in Children with Celiac Disease: A Saudi Tertiary Center Experience by Meshari A. Alaifan, Ammar Khayat, Rana Y. Bokhary, Abdulhameed Ibrahim, Yagoub Bin-Taleb, Bakr H. Alhussaini, Omar I. Saadah

“…The esophageal biopsy results reported were basal cell hyperplasia in 24 patients (32.9%), esophageal eosinophilia in 23 patients (31.5%), and EoE in 3 patients (4.1%). …”
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