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27961
Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato
Published 2022-01-01“…The abilities to adhere and colonize a host surface, effectively damage host cell walls, regulate signal transduction to manage infection, and survive in a hostile plant environment are proposed as important factors for the pathogenesis of S. lycopersici in tomato. …”
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27962
Investigating some biological activities of ethanolic extract from Chloranthus japonicus Sieb. leaves
Published 2024-09-01“…We also demonstrated that this extract at low concentrations (7.8125 - 31.25 µg/ml) could improve the proliferation of the mouse fibroblast NIH-3T3 cell line. However, at these concentrations, the extract did not show any inhibitory effect on the growth of some opportunistic pathogens, including S. aureus, P. aerugionsa, E. faecalis, and E. coli; and in vitro immunomodulatory effect on LPS-stimulated Raw 264.7 model. …”
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27963
A Study of the Different Strains of the Genus <i>Azospirillum</i> spp. on Increasing Productivity and Stress Resilience in Plants
Published 2025-01-01“…Different species of <i>Bacillus</i> spp. can increase the growth, yield, and biomass of plants by increasing the availability of nutrients; enhancing the solubilization and subsequent uptake of nutrients; synthesizing indole-3-acetic acid; fixing nitrogen; solubilizing phosphorus; promoting the production of phytohormones; enhancing the growth, production, and quality of fruits and crops via enhancing the production of carotenoids, flavonoids, phenols, and antioxidants; and increasing the synthesis of indoleacetic acid (IAA), gibberellins, siderophores, carotenoids, nitric oxide, and different cell surface components. The aim of this manuscript is to survey the effects of <i>Azospirillum</i> spp. and <i>Bacillus</i> spp. by presenting case studies and successful paradigms in several horticultural and agricultural plants.…”
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27964
Systemic inflammatory response index improves prognostic predictive value in intensive care unit patients with sepsis
Published 2025-01-01“…Multiple linear regression analysis revealed a significant positive correlation between SIRI and both blood cell count and Sequential Organ Failure Assessment (SOFA) score. …”
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27965
Investigating the Effect of Urban New Technologies on the Iranian Lorry Drivers’ Behavior
Published 2021-01-01“…To achieve the goals, the required information was categorized into six categories: traffic tonnage, not fastening the seatbelt, speeding, technical defect, talking on cell phone, and lacking towing worksheet; these factors are known as dependent variables. …”
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27966
Network Pharmacology and Molecular Docking Analyses of the Synergistic Mechanism of Babao Dan and Oxaliplatin in Colorectal Cancer
Published 2022-06-01“…Twenty-four core targets were determined from the 74 intersection targets, which were related to the positive regulation of kinase activity, the positive regulation of cell migration, and peptidyl-serine modification in GO biological process. …”
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27967
A Clone Selection Based Real-Valued Negative Selection Algorithm
Published 2018-01-01“…Then, the algorithm considers centers of clusters as antigens, randomly generates initial immune cell population in the qualified range, and executes the clonal selection algorithm. …”
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27968
Evaluation of Feulgen Reaction for Quantitative DNA Analysis in Oral Leukoplakia: Insights into Malignant Transformation Risk
Published 2024-12-01“…Background: Oral leukoplakia is a potentially malignant disorder with a significant risk of transformation into oral squamous cell carcinoma. The Feulgen reaction, a DNA-specific staining technique, has been widely used for the quantitative analysis of DNA content in various tissues. …”
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27969
Sudden Vision Loss Secondary to Optic Nerve Infiltration as a Presenting Symptom of Metastatic Lung Adenocarcinoma
Published 2022-01-01“…To report a rare case of left-sided metastatic optic nerve infiltration and right-sided choroidal mass with exudative retinal detachment caused by EGFR exon 19 deletion positive non-small-cell lung adenocarcinoma that responded to targeted therapy with osimertinib (EGFR-TKI). …”
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27970
siRNA therapeutics for effective management of rheumatoid arthritis
Published 2025-01-01“…Several treatments are available for RA, including analgesics, corticosteroids, DMARDs, biological agents, combinational therapy, epigenetic and cell therapies which play a crucial role in preventing joint function deterioration, inflammation, synovial edema, etc. …”
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27971
Artificial Neural Network-Based System for PET Volume Segmentation
Published 2010-01-01“…Experimental and Monte Carlo simulated PET phantom data sets and clinical PET volumes of nonsmall cell lung cancer patients were utilised to validate the proposed algorithm which has demonstrated promising results.…”
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27972
Elucidating the potential of EGFR mutated NSCLC and identifying its multitargeted inhibitors
Published 2025-01-01“…Mutations in the epidermal growth factor receptor (EGFR) gene are frequently found in non-small cell lung cancer (NSCLC). Since curcumin and CB[2]UN support various medicinal applications in drug delivery and design, we investigated the effect of curcumin and CB[2]UN-based drugs in controlling EGFR-mutant NSCLC through a dodecagonal computational approach. …”
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27973
Halo-RPD: searching for RNA-binding protein targets in plants
Published 2024-03-01“…Labeling of the fusion protein with custom-made fluorescent dyes makes it possible to study protein expression and to localize it in the cell or the whole organism. A high-affinity substrate has been created to allow covalent binding by chimeric proteins, minimizing protein loss during protein isolation. …”
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27974
Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics
Published 2024-12-01“…During hemorrhagic shock, hypoperfusion leads to cell necrosis and the release of CIRP into circulation, triggering both systemic inflammation and local tissue damage. …”
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27975
Carvacrol alleviates acrylamide-induced hepatotoxicity in rats: an experimental insights
Published 2023-12-01“…<p> <b>Results:</b> In microscopic examination, it was determined that AA causes hydropic/vacuolar degeneration, fatty changes, necrosis/apoptosis, bile duct proliferation, hepatic cord dissociation, congestion, megalocytosis and mononuclear cell infiltration. Parallelly, AA raised the levels of ALP, AST, and ALT. …”
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27976
Clinical and Biochemical Features Used to Classify Type-1 and Type-2 Diabetes: A Scoping Review
Published 2024-04-01“…While age at diagnosis, autoimmune markers, and beta-cell function are among the crucial clinical parameters, biochemical indicators like C-peptide levels and antibody analyses play a pivotal role. …”
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27977
Comparison of glaucoma progression rate in glaucoma patients at different stages using guided progression analysis with optical coherence tomography
Published 2025-01-01“…Abstract Background The aim of the present study was to compare the rates of change in Ganglion Cell- Inner Plexiform Layer (GCIPL) and Retinal Nerve Fiber Layer (RNFL) thickness, as measured by Optical Coherence Tomography (OCT) Guided Progression Analysis (GPA) program in control group, Primary Open Angle Glaucoma (POAG) and Pseudoexfoliation Glaucoma (PXG) eyes. …”
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27978
Comparison of some hematological and serum biochemical variables in kangal akkaraman, texel and Île de france ewes in lactation period within sivas province
Published 2021-12-01“…Hematological and biochemical variables analysis were performed using automatic cell counting and autoanalyzer devices.<p> <b>Results: </b>There was no significant difference in WBC, Hb, MCHC, MPV levels between ewe breeds (p>0.05). …”
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27979
Effects of V4c-ICL Implantation on Myopic Patients’ Vision-Related Daily Activities
Published 2016-01-01“…Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), endothelial cell density (ECD), and vault were recorded and vision-related daily activities were evaluated at 3 months after operation. …”
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27980
SARS-CoV-2: Molecular Structure, Pathogenesis, Potential Therapeutic Targets, and Immune Response of the Infected Subject
Published 2022-01-01“…Through a documentary review of literature, the authors describe virological and molecular aspects of SARS-CoV-2, the intimate mechanisms of cell infection, and potential therapeutic targets. …”
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