Evaluation of CD4+ T Lymphocyte Counts to Predict Survival of ICU Patients with Sepsis Using Sepsis-3 Criteria: A Prospective Cohort Study by Guoge Huang, Xusheng Li, Chunmei Zhang, Haizhong Li, Mengling Jian, Chunyang Huang, Yingqin Zhang, Luhua Xian, Hongke Zeng, Yuanyuan Xia, Wenqiang Jiang

“…Peripheral blood samples were collected within 24 hours of enrollment or measurement of blood cell analysis and biomarkers of CD4+ T lymphocytes and CD8+ T lymphocytes. …”
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ATO/Polyaniline/PbS Nanocomposite as Highly Efficient Photoelectrode for Hydrogen Production from Wastewater with Theoretical Study for the Water Splitting by Mohammed A. H. Khalafalla, N. M. A. Hadia, Asmaa M. Elsayed, Mansoor Alruqi, Wassim El Malti, Mohamed Shaban, Mohamed Rabia

“…Finally, the mechanism explains the H2 generation reaction using three-electrode cell.…”
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Impact de la forêt sur l’évolution des ressources en eau en moyenne montagne alpine depuis le milieu du XIXe siècle (massif de Chartreuse, France) by Dominique Dumas

“…Au total, le bilan hydrologique a donc été notablement modifié, avec une quantité d’eau disponible pour l’écoulement, ou les réserves souterraines, plus réduite que celle définie traditionnellement à partir des uniques relevés météorologiques.…”
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Investigation of rs1746661 Polymorphism in FNDC5 Gene in Obese Patients by Elham Hadi, Hashem Nayeri, Ali Mohammad Ahadi, Ziba Rezvani Sichani

“…This protein is cleaved by an unknown protease at the cell surface. This study aimed to investigate the rs1746661 polymorphism in the FNDC5 gene among obese patients. …”
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Structural Modifications Reveal Dual Functions of the C-4 Carbonyl Group in the Fatty Acid Chain of Ipomoeassin F by Arman Khosravi, Precious Nnamdi, Alexa May, Kelsey Slattery, Robert E. Sammelson, Wei Q. Shi

“…Ipomoeassin F (Ipom-F) is a plant-derived macrocyclic resin glycoside that potently inhibits cancer cell growth through blockage of Sec61-mediated protein translocation at the endoplasmic reticulum. …”
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Modified Technique for Scleral-Sutured Fixation with the Double Knots Technique for Posterior Chamber Intraocular Lens: Short-Term Observation by Zhizhong Wu, Caijuan Liu, Yanhui Xu, Wei Dong, Zhimin Chen

“…There were no statistical differences between the preoperative and postoperative corneal endothelial cell density (p=0.71). The postoperative complications included transient increased intraocular pressure in 5 eyes (24%). …”
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Le lien entre la motivation sportive et le stress perçu chez les élèves-athlètes marocains. Cas de la délégation provinciale de Béni-Mellal by Abdelouahd OUAZOUL, Nadia JEMJAMI

“…Pour ce qui concerne la motivation dans le sport, mous avons souligné la prédominance de deux sous-dimensions de l’outil de mesure à savoir celle de la régulation introjectée et de la régulation externe. …”
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FastContext: A tool for identification of adapters and other sequence patterns in next generation sequencing (NGS) data by E. Viesná, V. Fishman

“…NGS library preparation protocols may include steps with incorporation of various service sequences, such as sequencing adapters, primers, sample-, cell-, and molecule-specific barcodes. Despite a fairly high level of current knowledge, during the protocol development process researches often have to deal with various kinds of unexpected experiment outcomes, which result either from lack of information, lack of knowledge, or defects in reagent manufacturing. …”
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Determinants of mortality after massive transfusion - A prospective study by Divya Venugopal, Susheela Jacob Innah, Aboobacker Mohamed Rafi, Ramesh Bhaskaran

“…METHODOLOGY: MT was defined as receiving >4 packed red blood cell (PRBC) units within 1 h with the anticipation of continued need for blood products. …”
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Unannounced phone-based pill counts for monitoring antiretroviral medication adherence in South Africa by Seth Kalichman, Ellen Banas, Bruno Shkembi, Moira Kalichman, Catherine Mathews

“…Results showed that lower UPC adherence was significantly associated with male gender, alcohol use, higher HIV viral loads, lower CD4 cell counts, running out of ART, and intentionally not taking ART. …”
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An autopsy case with tubular obstruction by impacted swollen blebs due to ischemic acute kidney injury by Yukako Akiyama, Mitsuhiro Sato, Yoshio Taguma

“…Because of the existence of hematuria with red blood cell casts and rapid deterioration of renal function and severe systemic symptoms such as loss of appetite and general fatigue, we started immunosuppressive therapy with steroids, considering a vasculitis-like condition with NS, and hemodialysis was also started for oliguria. …”
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Luteolin ameliorates rat model of metabolic syndrome-induced cardiac injury by apoptosis suppression and autophagy promotion via NR4A2/p53 regulation by Xiyan Dai, Bo Liang, Yaolin Sun

“…Cardiac NR4A2 and p53, as well as apoptotic (B-cell leukemia/lymphoma 2 [BCL-2], Caspase [CASP]-3, and CASP-9) and autophagic mediators (Sequestosome-1/p62, Microtubule-associated protein 1 A/1B-light chain 3 [LC3], and Beclin-1) were measured by RT-qPCR and ELISA. …”
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Common variable immunodeficiency: An uncommon cause of bronchiectasis, granulomatous disease, chronic liver disease, and enteropathy – Case report and review of literature by Veena Shamsudeen, Arun Hegde, Uday Bhanu Kovilapu, Nisha Verma, Anurag Jain

“…Common variable immune deficiency (CVID) is a primary immunodeficiency syndrome, characterized by a defective B cell function. Although there is no age or gender predilection, it is usually diagnosed between the second and fourth decades of life. …”
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Metabolomic profiling of amines in sepsis predicts changes in NOS canonical pathways. by Abel Tesfai, Niall MacCallum, Nicholas S Kirkby, Hime Gashaw, Nicola Gray, Elizabeth Want, Gregory J Quinlan, Sharon Mumby, James M Leiper, Mark Paul-Clark, Blerina Ahmetaj-Shala, Jane A Mitchell

“…The iNOS supporting capacity of plasma was determined using a mouse macrophage cell-based bioassay.<h4>Main results</h4>Of all the amines measured 22, including L-arginine and ADMA, displayed significant differences in samples from patients with sepsis. …”
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Acute Liver Failure among Patients on Efavirenz-Based Antiretroviral Therapy by Innocent Lule Segamwenge, Miriam Kaunanele Bernard

“…Liver biopsies were done for all the four cases and the results showed a heavy mixed inflammatory cell infiltrate with eosinophils. For three patients withdrawal of Efavirenz from their antiretroviral regimen was sufficient to restore transaminase levels to normal and led to improvement of clinical symptoms. …”
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Poorly differentiated thyroid cancer: Clinical, pathological, mutational, and outcome analysis by Amit Agarwal, Nelson George, Niraj Kumari, Narendra Krishnani, Prabhaker Mishra, Sushil Gupta

“…Introduction: Poorly differentiated thyroid cancer (PDTC) remains a challenge not only for pathologists and surgeons because of the difficulties associated with the diagnostic process and the compelling need for difficult thyroidectomy, but it is also of high clinical relevance because it is responsible for mortality in non-anaplastic follicular cell-derived thyroid cancer. Materials and Methods: Cases of PDTC within a 30-year period were reviewed by two independent pathologists. …”
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Analysis of the Cytokine Expression in the Aqueous Humor of Individuals with BRVO-Associated Macular Edema by Chengyi Zhu, Lanlan Pan, Qiong Yi, Qiping Wei

“…This study aimed to determine the expression levels of vascular endothelial growth factor (VEGF), interleukin-6 (IL-6), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in the aqueous humor of patients with macular edema (ME) caused by branch retinal vein occlusion (BRVO), as well as to investigate the relationship between the cytokines as mentioned earlier and best-corrected visual acuity (BCVA), ME, and the degree of ME from the molecular level. …”
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系统性红斑狼疮皮损角质形成细胞体外培养及细胞学观察

“…【目的】体外培养系统性红斑狼疮(SLE)皮损部位角质形成细胞(KC),观察其细胞学特性&#65377;【方法】 原代培养SLE皮损和正常皮肤的角质形成细胞,倒置显微镜观察细胞的形态特点,免疫荧光法进行角蛋白检测并计算细胞纯度;两步消化法纯化细胞;CCK-8(cell counting Kit-8)评价细胞的增殖情况,绘制生长曲线&#65377;流式细胞仪观察细胞的生长周期和凋亡情况&#65377;【结果】使用K-SFM(serum-free keratinocyte medium)无血清培养基能成功体外培养SLE皮损的角质形成细胞,呈铺路石样&#65377;结合人工纯化,能达到 > 95%的纯度;与正常对照相比,SLE皮损角质形成细胞进入指数生长期较迟(7 d vs. 4 d),但进入后增长迅速,S期比例为: (40.68 ± 1.81)% vs. (34.43 ± 1.24)%(P < 0.05);凋亡率高:(6.08 ± 0.72)% vs. (4.32 ± 0.44)%(P < 0.05)&#65377;【结论】 SLE皮损角质形成细胞培养难度大,细胞的生物学行为存在异常,可能为SLE发病的独立&#65380;始发因素,其致病机制值得深入研究和探讨&#65377;…”
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Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Ferroptosis, a recently identified form of regulated cell death driven by iron-dependent lipid peroxidation, has emerged as a significant contributor to post-MI cardiac injury. …”
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Evaluation of Early Prognostic Factors of Mortality in Patients with Acute Pancreatitis: A Retrospective Study by Wenzheng Zhang, Jiang Hu, Bihui Yao, Xvsheng Yang, Lei Song, Ting Yin, Lu Liang

“…Multivariate logistic regression showed that red cell distribution (RDW) (OR = 2.965, P=0.001) and creatinine (OR = 1.025, P=0.005) were early independent risk factors of AP mortality while albumin (OR = 0.920, P=0.032) levels reduced AP mortality. …”
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