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27781
Predicting the thickness of shallow landslides in Switzerland using machine learning
Published 2025-02-01“…We explored 39 different covariates, including metrics on terrain, geomorphology, vegetation, and lithology, at three different cell sizes. To train the ML models, 21 variables were chosen based on the variable importance derived from RF models and expert judgement. …”
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27782
Screening and evaluation of novel DPP-IV inhibitory peptides in goat milk based on molecular docking and molecular dynamics simulation
Published 2025-01-01“…The inhibition of DPP-IV by GPFPLL and LPYPY after in vitro digestion reached 31.90 % ± 1.80 % and 39.37 % ± 0.90 %, respectively. In a Caco-2 cell experiment, GPFPLL and LPYPY exhibited significant inhibition of DPP-IV, reaching 46.53 % ± 3.48 % and 65.98 % ± 2.87 %, respectively, when the concentration of each peptide was 2 mg/mL. …”
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27783
Human Neutrophil Defensin-1, -3, and -4 Are Elevated in Nasal Aspirates from Children with Naturally Occurring Adenovirus Infection
Published 2018-01-01“…Moreover, there was also increase in the neutrophil count, which is a known cell source of HNPs. Conclusion. Our finding supports the involvement of HNP-1, -3, and -4 in naturally occurring cold in children infected with adenovirus. …”
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27784
Structure of an ex vivoDrosophila TOM complex determined by single-particle cryoEM
Published 2025-01-01“…Most mitochondrial precursor proteins are encoded in the cell nucleus and synthesized on cytoplasmic ribosomes. …”
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27785
Epigenetic profiling for prognostic stratification and personalized therapy in breast cancer
Published 2025-01-01“…Low-MLEM patients exhibited improved prognosis, characterized by enhanced immune cell infiltration and higher responsiveness to immunotherapy. …”
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27786
Comparison of Metformin and Repaglinide Monotherapy in the Treatment of New Onset Type 2 Diabetes Mellitus in China
Published 2014-01-01“…Repaglinide had no effect on insulin sensitivity, but it improved β-cell function.…”
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27787
Phase separation of a microtubule plus-end tracking protein into a fluid fractal network
Published 2025-01-01“…Here, we have study the phase separation of Bik1, a CLIP-170 family member and key +TIP involved in budding yeast cell division. Bik1 is a dimer with a rod-shaped conformation primarily defined by its central coiled-coil domain. …”
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27788
How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies
Published 2018-01-01“…In the course of pSS, inflammatory cell infiltration consists mainly of lymphocytes infiltrating exocrine glands, which leads to their impaired function. …”
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27789
Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis
Published 2025-01-01“…A histopathological analysis revealed that camellia oil reduced inflammatory-cell infiltration and edema in the AD-affected skin. …”
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27790
Antibiofilm activity of 3,3'-diindolylmethane on Staphylococcus aureus and its disinfection on common food-contact surfaces
Published 2022-09-01“…DIM of 62.5 μmol/L inhibited the bacterial initial adhesion and proliferation, as well as cell motility; the release of extracellular DNA (eDNA) and extracellular polysaccharide (EPS) were reduced by 75 % and 69 %, respectively. …”
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27791
Vaccinomics Approach for Designing Potential Peptide Vaccine by Targeting Shigella spp. Serine Protease Autotransporter Subfamily Protein SigA
Published 2017-01-01“…Casein-degrading serine protease autotransporter of enterobacteriaceae (SPATE) subfamily protein SigA, an outer membrane protein, exerts both cytopathic and enterotoxic effects especially cytopathic to human epithelial cell type-2 (HEp-2) and is shown to be highly immunogenic. …”
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27792
Liver GlucokinaseA456V Induces Potent Hypoglycemia without Dyslipidemia through a Paradoxical Induction of the Catalytic Subunit of Glucose-6-Phosphatase
Published 2011-01-01“…Metabolite profiling in serum and liver extracts, together with changes in key components of glucose and lipid homeostasis, were analyzed and compared to GK wild-type transfected livers. Cell compartmentalization of the mutant but not the wild-type GK was clearly affected in vivo, demonstrating impaired GKRP regulation. …”
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27793
MARTRE family proteins negatively regulate CCR4-NOT activity to protect poly(A) tail length and promote translation of maternal mRNA
Published 2025-01-01“…Moreover, Martre knockout embryos show delayed 2-cell stage progression and compromised preimplantation development. …”
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27794
On the nascent wind of oxygen-rich AGB stars: scrutiny of a sample of nearby stars
Published 2024-05-01“…The commonly accepted mechanism governing the formation of the nascent wind in oxygen-rich AGB stars combines an initial boost above the photosphere, given by shock waves resulting from stellar pulsations and convective cell partition, with a subsequent acceleration fuelled by the radiation pressure of the star on dust grains. …”
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27795
Outage and Throughput Analysis of Cooperative Non-Orthogonal Multiple Access based SWIPT Cognitive Relay Network
Published 2025-01-01“…This, in turn, improves the data rate of far/cell edge users.…”
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27796
20 kHz X-ray diffraction on Cu thin films explores thermomechanical fatigue at high strain-rates
Published 2025-03-01“…Whereas on the intragranular scale, Cu exhibited ductile dynamic recovery, where accumulated dislocations formed cell structures and low-angle grain boundaries, helping to relieve part of the tensile stress. …”
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27797
A Millimeter-Wave Single-Bit Reconfigurable Intelligent Surface With High-Resolution Beam-Steering and Suppressed Quantization Lobe
Published 2025-01-01“…We incorporate fixed, random phase delays at each unit cell of the surface which breaks the periodicity of the phase quantization error and suppresses side lobes. …”
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27798
Transsulfuration pathway activation attenuates oxidative stress and ferroptosis in sickle primary erythroblasts and transgenic mice
Published 2025-01-01“…Little of the TSS pathway in antioxidant capacity in sickle cell disease (SCD) is known. Here, we evaluate the effects of TSS pathway activation through cystathionine beta-synthase (CBS) to attenuate reactive oxygen species (ROS) and ferroptosis stresses in SCD. …”
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27799
Influence of the Decelerator Grid on the Optical Performance of the Ion Thruster
Published 2019-01-01“…In this paper, a three-dimensional Immersed Finite Element Method-Particle in Cell-Monte Carlo Collision (IFE-PIC-MCC) algorithm was adopted to investigate the effect of the decelerator grid on the optical performance under crossover and normal circumstances. …”
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27800
Analysis of MLKL, RIP1 and RIP3 Immunostaining Markers in Human Liver Tissue from Fatal Yellow Fever Cases: Insights into Necroptosis
Published 2024-12-01“…Necroptosis is a regulated form of cell death implicated in several pathological conditions, including viral infections. …”
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