Design and Development of a Bespoke Rotary Friction Welding Machine in Exploration of Joining Dissimilar Materials for Nuclear Applications by Michail Dellepiane, Laurie Da Silva, Athanasios Toumpis

“…The proposed setup is designed to be easily manufactured, employing the use of a calibrated drill press and load cell, thus ensuring welding parameters such as rotational speed and applied axial load are monitored. …”
Get full text

Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1 by Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan

Get full text

Metabolic Basis for Thyroid Hormone Liver Preconditioning: Upregulation of AMP-Activated Protein Kinase Signaling by Luis A. Videla, Virginia Fernández, Pamela Cornejo, Romina Vargas

“…These include antioxidant, antiapoptotic, and anti-inflammatory mechanisms, repair or resynthesis of altered biomolecules, induction of the homeostatic acute-phase response, and stimulation of liver cell proliferation, which are required to cope with the damaging processes set in by IR.…”
Get full text

Hagiografie şi ideologie by Cristina Balinte

“…Nous allons poursuivre d’abord les acceptions principales données au genre hagiographique, en prenant aussi en discussion la pertinence d’encadrement dans la catégorie de la biographie des gens exceptionnels ou celle du discours sur les vertus, ce qui porte le nom d’arétologie. …”
Get full text

Postharvest Analysis of Lowland Transgenic Tomato Fruits Harboring hpRNAi-ACO1 Construct by Bita Behboodian, Zainon Mohd Ali, Ismanizan Ismail, Zamri Zainal

“…Results showed that transgenic lines harboring the hpRNA-ACO1 construct had lower ethylene production and a longer shelf life of 32 days as compared to 10 days for wild-type fruits. Changes in cell wall degrading enzyme activities were also investigated in cases where the transgenic fruits exhibited reduced rates of firmness loss, which can be associated with a decrease in pectin methylesterase (PME) and polygalacturonase (PG) activities. …”
Get full text

Potential role of CTNNA3 and FRMPD4 in vascular tumorous thrombosis of colon adenocarcinoma by Bin Liu, Yu Xiang, Weihua Guo

“…They are also closely related to the immune microenvironment and the infiltration of immune cell subtypes. Based on gene mutation analysis, gene deletion is suggested to be related to vascular invasion indicators. …”
Get full text

A Prospective Study Assessing Tumour Response, Survival, and Palliative Care Outcomes in Patients with HIV-Related Kaposi's Sarcoma at Queen Elizabeth Central Hospital, Blantyre, M... by H. Francis, M. J. Bates, L. Kalilani

“…At baseline assessment, the median CD4 T-cell count was 263, and 50% patients had evidence of peripheral neuropathy. …”
Get full text

Evaluation of controls, quality control assays, and protocol optimisations for PacBio HiFi sequencing on diverse and challenging samples by Iraad F. Bronner, Emma Dawson, Naomi Park, Olaf Piepenburg, Michael A. Quail

“…We demonstrate that contaminants present in some samples are the cause of very low HiFi yield, and show that these contaminants can negatively affect the PacBio internal sequencing control and samples multiplexed on the same SMRT Cell. We found that consistently high yields could be obtained if an amplification workflow was utilised, namely PacBio’s ultra-low input library preparation protocol.…”
Get full text

Demographics and Haematological Parameters in Patients with Type II Diabetes Mellitus in Uttar Pradesh – A Comparative study by Priyanka Singh, Pradakhshana Vijay, Shaleen Chandra, Sanjay Kumar Singh, Diksha Singh, Priya Devi

“…Aim: To compare the demographics and haematological parameters like haemoglobin, white blood cell and platelet values in type II diabetes mellitus patients. …”
Get full text

Mechanism of Action of Lacticaseibacillus paracasei HNU502 and Fecal Microbiota Transplantation in Alleviating Antibiotic Side Effects by CHEN Lin, LI Ao, LI Jiahe, ZHANG Zeng, ZHANG Jiachao

“…Both FMT and probiotic supplementation improved gut microbiota composition, but to varying degrees, prevented goblet cell loss, and increased the contents of mucin-2 (MUC-2) and zonula occludens-1 (ZO-1), thus aiding gut mucosal recovery. …”
Get full text

Integrated gene expression and alternative splicing analysis in human and mouse models of Rett syndrome by Silvia Gioiosa, Silvia Gasparini, Carlo Presutti, Arianna Rinaldi, Tiziana Castrignanò, Cecilia Mannironi

“…Human and mouse dysregulated genes are involved in two main functional categories: cell-extracellular matrix adhesion regulation and synaptic functions, the first category more significantly enriched in human datasets. …”
Get full text

STUDI JUMLAH TROMBOSIT ANTARA PENDONOR LAKI-LAKI DAN PEREMPUAN PADA USIA YANG BERBEDA DI UNIT TRANSFUSI DARAH CABANG KOTA MALANG by Anis Nur Khasanah, Suyadi Suyadi

“…Blood is part of the body which has 6-8 % of total body weight which include of the blood cell and plasma. Thrombocyte is one of component in the blood which has an important function in blood coagulation. …”
Get full text

A Novel Hybrid MPPT Controller for PEMFC Fed High Step-Up Single Switch DC-DC Converter by Shaik Rafikiran, C. H. Hussaian Basha, C. Dhanamjayulu

“…At present, there are different types of Renewable Energy Resources (RESs) available in nature which are wind, tidal, fuel cell, and solar. The wind, tidal, and solar power systems give discontinuous power supply which is not suitable for the present automotive systems. …”
Get full text

Platelet Volume Parameters as Predictors of Valvular Thrombosis Risk in Patients with Aortic and Mitral Valve Replacement by Boshra Pourbashash MD, Seyed Parsa Eftekhar MD, Pooria Ahmadi MD, Arash Jalali PhD, Ali Hosseinsabet MD, Reza Mohseni Badalabadi MD

“…This study aimed to investigate the predictive value of platelet volume parameters, including mean platelet volume (MPV), platelet distribution width (PDW), and platelet-large cell ratio (P-LCR), for valvular thrombosis risk in patients undergoing valve replacement therapy. …”
Get full text

GPX modulation promotes regenerative axonal fusion and functional recovery after injury through PSR-1 condensation by Su-Hyuk Ko, Kyung-Ah Cho, Xin Li, Qitao Ran, Zhijie Liu, Lizhen Chen

Get full text

Relationship between Altered Platelet Morphological Parameters and Retinopathy in Patients with Type 2 Diabetes Mellitus by Tolga Yilmaz, Ahu Yilmaz

“…Mean platelet volume (MPV), platelet distribution width (PDW), platelet large cell ratio (PLCR), plateletcrit (PCT) values, and platelet count were measured in the studied groups. …”
Get full text

Evolutionary Explanations of the “Actuarial Senescence in the Wild” and of the “State of Senility” by Giacinto Libertini

“…A large set of data suggests that progressive reduction of fitness and senile decay in vertebrates are in correlation with the decline of cell replication capacities. However, the limits in such capacities are hardly explained in evolutionarily terms by current gerontological theories that rule out fitness decline as something genetically determined and regulated, and therefore somehow favored by natural selection.Four theories are tested as possible explanations of the “increasing mortality with increasing chronological age in populations in the wild” (“IMICAW”[1]), alias “actuarial senescence in the wild”[2], and of the observed negative correlation between extrinsic mortality and the ratio between deaths due to intrinsic mortality and deaths due to extrinsic mortality. …”
Get full text

PREVENTION OF COMPLICATIONS IN CASTRATE-REFRACTORY PROSTATE CANCER PATIENTS WITH BONE METASTASES by K. M. Nushko, A. S. Kalpinskiy, A. D. Kaprin

“…Frequent localization of metastatic lesions in the bones is due to tumor cell tropism of prostate cancer to the bone. Metastatic bone disease, as well as long-term HT conducted in patients with metastatic prostate cancer, leads to irreversible disruption of bone remodeling, which may be accompanied by osteoporosis and fragility fractures. …”
Get full text

Comparison of Mechanical Resistance to Maximal Torsion Stress in Original and Nonoriginal or Compatible Prosthetic Implant Screws: An In Vitro Study by António Sérgio Silva, José Manuel Mendes, Tiago Araújo, Carlos Aroso, Pedro Barreiros

“…The screws were tightened with an MIS® torquemeter until their respective fracture, and the fracture point was measured through the equipment’s load cell, CS-Dental Testing Machine®. The screws were analyzed under an Olympus® SZ61 microscope. …”
Get full text

Pleiotropic effects of a recessive Col1a2 mutation occurring in a mouse model of severe osteogenesis imperfecta. by Michelangelo Corcelli, Rachel Sagar, Ellen Petzendorfer, Mohammad Mehedi Hasan, Fleur S van Dijk, Anna L David, Pascale V Guillot

“…The phenotype of differentiated OIM osteoblasts also differs from that of wild type mature osteoblasts, with upregulated oxidative cell stress and autophagy pathways. The extracellular accumulation of defective type I collagen fibres contributes to activation of the TGF-β signalling pathway and activates the inflammatory pathway. …”
Get full text