Tumor-Induced Osteomalacia: Increased Level of FGF-23 in a Patient with a Phosphaturic Mesenchymal Tumor at the Tibia Expressing Periostin by Anke H. Hautmann, Josef Schroeder, Peter Wild, Matthias G. Hautmann, Elisabeth Huber, Patrick Hoffstetter, Martin Fleck, Christiane Girlich

“…Electron microscopy demonstrated a poorly differentiated mesenchymal tumor with a multifocal giant cell component and evidence of neurosecretory-granules. …”
Get full text

Proteomic Analysis of the Vitreous following Experimental Retinal Detachment in Rabbits by Nakul Mandal, Geoffrey P. Lewis, Steven K. Fisher, Steffen Heegaard, Jan U. Prause, Morten la Cour, Henrik Vorum, Bent Honoré

“…The pathogenesis of rhegmatogenous retinal detachment (RRD) remains incompletely understood, with no clinically effective treatment for potentially severe complications such as photoreceptor cell death and proliferative vitreoretinopathy. Here we investigate the protein profile of the vitreous following experimental retinal detachment using a comparative proteomic based approach. …”
Get full text

Long Noncoding RNA–Messenger RNA (lncRNA–mRNA) Network in Resistance to Gummy Stem Blight (<i>Stagonosporopsis cucurbitacearum</i>) of Melon Plant Introduction (PI) 420145 by Rui Zhang, Jing Chen, Yongbing Zhang, Xiumei Lu, Chunyan Cheng, Ji Li, Qunfeng Lou, Yuhui Wang, Chuntao Qian

“…Our results revealed that PI 420145 exhibits a thicker waxy layer on the leaf surface and limited conidial germination without obvious signs of cell damage compared to ‘Baipicui’. The transcriptomic analysis identified a total of 23,078 differentially expressed genes (DEGs) and 974 differentially expressed long noncoding RNAs (DELs). …”
Get full text

Delays in Blood Work and Disease Burden: A Cross-Sectional Analysis of Unmet Blood Work Need and Seven Key Health Conditions Across 21 Countries by Eunice Chung, Louisa Ewald, Nicholas J. Kassembaum, Nicholas J. Kassembaum, Taylor Noyes, Emmanuela Gakidou, Emmanuela Gakidou, Ali H. Mokdad, Ali H. Mokdad

“…ObjectivesThis study analyzes survey data across 21 countries to explore correlations between delays in blood testing and the prevalence of seven health conditions: thalassaemias, sickle cell disorders, malaria, HIV, high fasting plasma glucose, impaired kidney function, and high LDL cholesterol.MethodsWe analyzed Pandemic Recovery Survey data via multivariable logistic regression to compare blood test delays between individuals with and without medical conditions, while adjusting for sociodemographic factors. …”
Get full text

Dissection of the long-range circuit of the mouse intermediate retrosplenial cortex by Yuxiao Li, Miao Ren, Bimin Liu, Tao Jiang, Xueyan Jia, Haili Zhang, Hui Gong, Xiaojun Wang

“…The systematic study on long-range connections across RSP subregions and cell types may provide useful information for future revealing of RSP working mechanisms.…”
Get full text

Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen by Mohamed Al-Salahy, Bushra Shnawa, Gamal Abed, Ahmed Mandour, Ali Al-Ezzi

“…Patients with parasitaemia tended to have significantly lower hemoglobin, hematocrit, white blood cell count, lymphocytes, and platelets, compared with healthy normal subjects. …”
Get full text

FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy by Na Zhang, Yang Meng, Song Mao, Huiling Ni, Canhua Huang, Licong Shen, Kun Fu, Lu Lv, Chunhong Yu, Piyanat Meekrathok, Chunmei Kuang, Fang Chen, Yu Zhang, Kai Yuan

“…Increasing O-GlcNAcylation in patient-derived endometrial epithelial organoids promotes proliferation and stem-like cell properties, whereas decreasing O-GlcNAcylation limits the growth of endometrial cancer organoids. …”
Get full text

A New Kinetic Spectrophotometric Method for the Quantitation of Amorolfine by César Soto, Cristian Poza, David Contreras, Jorge Yáñez, Fallon Nacaratte, M. Inés Toral

“…Amorolfine (AOF) is a compound with fungicide activity based on the dual inhibition of growth of the fungal cell membrane, the biosynthesis and accumulation of sterols, and the reduction of ergosterol. …”
Get full text

Distribution of Adiponectin Receptors 1 and 2 in the Rat Olfactory Bulb and the Effect of Adiponectin Injection on Insulin Receptor Expression by Alfredo Miranda-Martínez, Octavio Fabián Mercado-Gómez, Virginia Arriaga-Ávila, Rosalinda Guevara-Guzmán

“…We found that AdipoRs were localized in all cell layers and in both neurons and astrocytes. We observed the presence of mRNA transcripts and immunoblot analysis confirmed the protein on the intact OB; APN injection in the OB resulted in a slight decrease of the total InsR and Akt phosphorylation and a reduction of phopho-InsR content. …”
Get full text

An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection by Yuhao Zheng, Shu Wang, Wenhe Jin, Zhuoxuan Li, Guoju Yang, Xiaoxu Li, Ning Li, Yue Wang, Fan Sheng, Zhiming Song

“…The physicochemical properties of piezoelectric antibacterial scaffolds were analyzed. Bacterial, cell, and animal experiments were performed to characterize the antibacterial and infection treatment capabilities of piezoelectric scaffolds. …”
Get full text

Maternal Aerobic Exercise during Pregnancy Can Increase Spatial Learning by Affecting Leptin Expression on Offspring's Early and Late Period in Life Depending on Gender by Ayfer Dayi, Sinem Agilkaya, Seda Ozbal, Ferihan Cetin, Ilkay Aksu, Celal Gencoglu, Sultan Cingoz, Cetın Pekcetin, Kazim Tugyan, Berkant Muammer Kayatekin, Nazan Uysal

“…In our study, maternal running during pregnancy resulted in significant increase in the expression of leptin receptor but not in prepubertal female pups, enhanced hippocampal cell survival, and improved learning memory capability in prepubertal and adult rat pups, as compared to the control group. …”
Get full text

Analysis of the Complete Genome Sequence of a Novel, Pseudorabies Virus Strain Isolated in Southeast Europe by Zsolt Csabai, Dóra Tombácz, Zoltán Deim, Michael Snyder, Zsolt Boldogkői

“…We also found that the adaptation of PRV to cell culture does not lead to any tendentious genetic alteration in the viral genome. …”
Get full text

Using Brown Algae in the Plant–Soil System: A Sustainable Approach to Improving the Yield and Quality of Agricultural Crops by Oscar Sariñana-Aldaco, Luz Leticia Rivera-Solís, Adalberto Benavides-Mendoza, Armando Robledo-Olivo, Rosa María Rodríguez-Jasso, Susana González-Morales

“…This type of biostimulants derived from brown algae improve seed germination, increase the accumulation of plant biomass by accelerating cell division and elongation, activating the antioxidant system of plants, making them more resistant to stress, and contributes to the absorption and translocation of nutrients present in the soil. …”
Get full text

Mitochondrial DNA Structure in <i>Trypanosoma cruzi</i> by Alfonso Herreros-Cabello, Francisco Callejas-Hernández, Manuel Fresno, Núria Gironès

“…Kinetoplastids display a single, large mitochondrion per cell, with their mitochondrial DNA referred to as the kinetoplast. …”
Get full text

Okra juice used for rapid wound healing through its bioadhesive and antioxidant capabilities by Biao Zhang, Yuanqiang Li, Kaijie Wu, Liqi Wei, Yining Chen, Yuan Zhang, Yiping Ren, Tianshu Zou, Pengcheng Yu, Hongxia Ma, Rui Chen, Xin Liu, Yan Cheng

“…The strongest adhesion ability of this bioadhesive to wet tissue was 5.51 kPa, the ability to inhibit 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl radical, superoxide radical, hydroxyl radical, and hydrogen peroxide was 56.58 %, 49.94 %, 53.86 %, and 52.89 %, respectively, and the ability to promote cell proliferation was 181.46 %. The levels of pro-inflammatory tumor necrosis factor alpha (33.17 %) and Interleukin-6 (46.73 %) were significantly reduced. …”
Get full text

Enhanced Handoff Scheme for Downlink-Uplink Asymmetric Channels in Cellular Systems by Sunghyun Cho, Ji-Su Kim, Jae-Hyun Kim

“…This asymmetry can lead to a downlink-uplink asymmetric channel condition being experienced by cell edge users. This paper proposes a handoff scheme to cope effectively with downlink-uplink asymmetric channels. …”
Get full text

A Genomic‐Based Workflow for eDNA Assay Development for a Critically Endangered Turtle, Myuchelys georgesi by Holly V. Nelson, Arthur Georges, Katherine A. Farquharson, Elspeth A. McLennan, Jane L. DeGabriel, Katherine Belov, Carolyn J. Hogg

“…ABSTRACT Environmental DNA (eDNA) analysis has become a popular conservation tool for detecting rare and elusive species. eDNA assays typically target mitochondrial DNA (mtDNA) due to its high copy number per cell and its ability to persist in the environment longer than nuclear DNA. …”
Get full text

Potential applications of PLGA/PVA coaxial nanofibers with controlled release for guiding tissue regeneration by Huinan Zhang, Dongchao Ji, Kunlong Zhao, Zhuoheng Li, Shuo Yang, Peng Wang, Wenxin Cao, Yu Sun

“…Biomedical scaffolds are increasingly used in bone repair due to their exceptional ability to support cell growth and proliferation. This study developed a multifunctional poly(lactic-co-glycolic acid) (PLGA)/polyvinyl alcohol (PVA)/metronidazole coaxial electrospun nanofiber membrane to overcome the limitations of current bone tissue self-repair mechanisms. …”
Get full text

High-Risk Microgranular Acute Promyelocytic Leukemia with a Five-Way Complex Translocation Involving PML-RARA by Benjamin Powers, Diane Persons, Deepthi Rao, Janet Woodroof, Tara L. Lin

“…Given his elevated white blood cell count at presentation, intrathecal chemotherapy for central nervous system prophylaxis was also given. …”
Get full text

Effectiveness of ethanol extract of Morinda citrifolia L. as an anti-inflammatory: A preclinical study by Mega Hayati, Ali Napiah Nasution, Ermi Girsang, Adek Amansyah, Fioni

“…However, histopathological analysis revealed persistent inflammatory cell infiltration and synovial hyperplasia in treated groups, indicating incomplete tissue repair compared to triamcinolone. …”
Get full text