Design, Synthesis and Potential Anti-Proliferative Activity of Some Novel 4-Aminoquinoline Derivatives by Ghorab Mostafa M., Al-Said Mansour S., Arafa Reem K.

“…All the newly synthesized comounds were tested for in vitro antiproliferative activity against the MCF-7 breast cancer cell line. Seventeen of the novel compounds showed higher activity than the reference drug doxorubicin. …”
Get full text

Influence of Starkeya novella on Mechanical and Microstructural Properties of Cement Mortars by Onesmus Mulwa Munyao, Joseph Karanja Thiong’o, Jackson Muthengia Wachira, Daniel Karanja Mutitu, Romano Mwirichia

“…Bacterial solution of 1.0 × 107 cell/mL concentration was used as either mix water, curing media, or both. …”
Get full text

Exploring mechanisms of insulin action and strategies to treat diabetes by Takayoshi Sasako

“…Insulin is a hormone that positively regulates anabolism and cell growth, whereas diabetes mellitus is a disease characterized by hyperglycemia associated with impaired insulin action. …”
Get full text

Influence of Gallic Acid and Thai Culinary Essential Oils on Antibacterial Activity of Nisin against Streptococcus mutans by Pimsumon Jiamboonsri, Pimpikar Kanchanadumkerng

“…The results demonstrated that kaffir lime leaf (KLL) oil, lemongrass (LG) oil, and GA showed a potent anti-S. mutans activity and inhibited biofilm formation with the possible mechanism targeted on the cell membrane. Additionally, KLL oil revealed anti-S. mutans synergism with GA, LG oil, and chlorhexidine with the fractional inhibitory concentration (FIC) indexes ≤ 0.5. …”
Get full text

Structure simulation-based comparison of active site variations in fungal ornithine decarboxylases by Min Jeong Kim, Jeong Ho Chang

“…Polyamines play crucial roles in various biological processes, including cell proliferation and differentiation, immune response modulation, and signal transduction. …”
Get full text

Incoherent Integration Detection Method of Airborne Phased Array Radar in a Multipath Environment by Yili Hu, Yongbo Zhao, Sheng Chen

“…Considering these two characteristics, this paper first proposes a target pairing algorithm for matching the DP range and multipath range of the same target in signal detection, and then, combined with the cell-averaging constant false alarm rate (CA-CFAR) detection model, an incoherent integration detection method for airborne PAR in the multipath environment is proposed. …”
Get full text

A novel broad-spectrum bacteriophage cocktail against methicillin-resistant Staphylococcus aureus: Isolation, characterization, and therapeutic potential in a mastitis mouse model. by Maryam Banar, Haniyeh Kamyab, Narges Torkashvand, Taghi Zahraei Salehi, Zargham Sepehrizadeh, Ahmad Reza Shahverdi, Mohammad Reza Pourmand, Mohammad Hossein Yazdi

“…The one-step growth curve displayed a rapid latent period (20-35 min) and substantial burst size (418 and 316 PFU/ cell). In silico analyses have confirmed the absence of antimicrobial resistance or virulence factor-encoding genes within their genomes. …”
Get full text

Continuous Delivery of D-Luciferin by Implanted Micro-osmotic Pumps Enables True Real-Time Bioluminescence Imaging of Luciferase Activity in Vivo by Shimon Gross, Ute Abraham, Julie L. Prior, Erik D. Herzog, David Piwnica-Worms

“…Bioluminescence imaging (BLI) of luciferase reporters in small animal models offers an attractive approach to monitor regulation of gene expression, signal transduction, and protein-protein interactions, as well as following tumor progression, cell engraftment, infectious pathogens, and target-specific drug action. …”
Get full text

Concurrent Central Diabetes Insipidus and Acute Myeloid Leukemia by Stephanie L. Pritzl, Daniel R. Matson, Mark B. Juckett, David J. Ciske

“…The patient received induction chemotherapy followed by allogeneic hematopoietic stem cell transplantation but experienced disease relapse and passed away nine months after initial diagnosis. …”
Get full text

Fano resonated, ultrathin, flexible and ultrawideband absorption featured nano-metaatom structure with dispersion gap optimized for optical range applications by Ahasanul Hoque, Mohammad Tariqul Islam, Ali F. Almutairi

“…Numerical analysis revealed that, on average 86.66% absorption achieved for 560 THz bandwidth peak absorption for the unit cell was 99.88% and the array shows 99.79%. Dispersion gap optimized based on mode 4 to incorporate all photons for phase and group velocity inside the nano metamaterial absorber. …”
Get full text

Rancang Bangun Pengemasan Produk Kacang Goreng Otomatis Berbasis Mikrokontroler by Yusni Hasanah, Nefy Puteri Novani

“…The tool made uses volume measurements to minimize error on the scales using a load cell sensors. The type of research used in making the final assignment is action research which is carried out carefully, logically and systematically. …”
Get full text

L'organisation en tant que configuration (imbriquée) de transactions by James R. Taylor

“…Le « paradoxe » se dissout cependant dans une théorie communicative, qui soutient que l’identité organisationnelle, et sa personnification, sont établies de la même manière que celles des individus. L’article présente ensuite une vision originale de l’organisation comme une « imbrication » de champs discursifs d’où émergent de multiples niveaux d’identité. …”
Get full text

A Comparative Double-blind Study to Evaluate the Efficacy of Coconut Water and Honey as Cytological Fixatives for Oral Smears by Bharadwaj Bordoloi, Aanchal Tandon, Arunima Goswami, Debojyoti Roy, Abhinav Srivastava, Apoorva Sharma

“…The following parameters were evaluated – nuclear staining, cytoplasmic staining, cell morphology, clarity of staining, and uniformity of staining. …”
Get full text

Mucormycosis Leading to Cerebral Edema and Cerebellar Tonsillar Herniation after Allogeneic Bone Marrow Transplant: A Case Report by Chetan Jeurkar, Lauren Margetich, Ziver Sahin

“…Mucormycosis following hematopoietic stem cell transplant (HSCT) carries a very high mortality rate. …”
Get full text

Expression of protein phosphatase 4 in different tissues under hypoxia by Yanyan Ma, Jing Hou, Dengliang Huang, Yaogang Zhang, Zhe Liu, Meiyuan Tian

“…A blood routine test was performed by an animal blood cell analyzer on rats cultured for different hypoxia periods at 4,500 m above sea level. …”
Get full text

Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host by Shikha Shrestha, JayaKrishna Chintanaboina, Samir Pancholy

“…Laboratory data was significant for a white blood cell count of 22,000/mm3 (normal: 4000–11000/mm3). …”
Get full text

Preparation and Characterization of Manganese Ferrite Aluminates by R. L. Dhiman, S. P. Taneja, V. R. Reddy

“…The formation of mixed spinel phase has been confirmed by X-ray diffraction analysis. The unit cell parameter `aO' is found to decrease linearly with aluminum concentration due to smaller ionic radius of aluminum. …”
Get full text

Gastric Cytoprotection as Basis of Gastrointestinal Mucosa Protection and Repair in Erosive Ulcerative Lesions of Various Aetiologies by K. V. Ivashkin, E. A. Izatullaev, V. R. Korneeva

“…SH-containing endogenous substances (L-cysteine, D,L-methionine, GSH) and exogenous molecules (methylmethionine-sulfonium chloride (MMSC), N-acetylcysteine) prevent damage due to the ability to absorb/neutralise free radicals released in xenobiotic-triggered cell damage, inhibit TNF-α expression, reduce the aspirin-induced leukocyte-endothelium adhesion and stimulate mucin release. …”
Get full text

Acute Left Internal Carotid Artery and Right Popliteal Artery Occlusion Related to Cisplatin-Gemcitabine Based Chemotherapy by Saman Zafar, Rashmika Potdar, Andrew Tiu, Gabor Varadi, John Leighton

“…We report a case of a 64-year-old male with Diffuse Large B-Cell Non-Hodgkin’s Lymphoma who presented with left-sided headache and right calf pain two weeks after starting Rituximab/Gemcitabine/Cisplatin/Dexamethasone chemotherapy. …”
Get full text

How energy determines spatial localisation and copy number of molecules in neurons by Cornelius Bergmann, Kanaan Mousaei, Silvio O. Rizzoli, Tatjana Tchumatchenko

“…Yet, there may also be global, currently unknown computational rules that are valid across different molecular species inside a cell. Surprisingly, our results show that the energy for molecular turnover is a significant cellular expense, en par with spiking cost, and which requires energy-saving strategies. …”
Get full text