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26961
Parvalbumin interneurons in the anterior cingulate cortex exhibit distinct processing patterns for fear and memory in rats
Published 2025-01-01“…The anterior cingulate cortex is responsible for multiple cognitive functions like fear, pain management, decision-making, risk and reward assessment, and memory consolidation. However, its cell-type-specific functions are not clearly understood. …”
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26962
A Case of Uterine Lymphangioleiomyomatosis Complicated by Tuberous Sclerosis Complex
Published 2022-01-01“…Lymphangioleiomyomatosis (LAM) is one of the presentations of perivascular epithelioid cell neoplasm that is frequently complicated by tuberous sclerosis complex (TSC). …”
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26963
Prussian Blue Analogues Derived Hollow FeCoP Nanocubes for Electrocatalytic Overall Water Splitting
Published 2025-01-01“…Importantly, when used as a bifunctional catalyst for overall water splitting, FeCoP can achieve a current density of 10 mA cm−2 at a low cell voltage of only 1.58 V and exhibits impressive durability. …”
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26964
A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma
Published 2011-01-01“…Niacinamide reduced importantly the mast cell infiltrate and showed improvement of solar elastosis in melasma skin. …”
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26965
Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemica...
Published 2018-01-01“…In addition, the in vitro bactericidal and cell viability studies were also carried out to further confirm the biocompatibility of the protective coating. …”
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26966
Evaluation of Cardioprotective Effect of 3,5,3′-Tri-iodo-L-thyronine in Isoproterenol-Induced Cardiotoxicity
Published 2011-01-01“…Lower heart weight, upregulation of cardiac myosin heavy chain alpha (MHC-α), and reduced inflammatory cell infiltration, myonecrosis, vacuolar changes, and a trend toward normal cardiac muscle fiber architecture in microscopic examination of cardiac tissue further support the cardioprotective effect of T3.…”
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26967
Cationic Polymers Inhibit the Conductance of Lysenin Channels
Published 2013-01-01“…These findings reveal key structural characteristics which may provide insight into lysenin’s functionality while opening innovative approaches for the development of applications such as transient cell permeabilization and advanced drug delivery systems.…”
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26968
A Novel Gel Polymer Electrolyte by Thiol-Ene Click Reaction Derived from CO2-Based Polycarbonate for Lithium-Ion Batteries
Published 2020-01-01“…The as-prepared composite membrane is used to assemble a prototype lithium iron phosphate cell and evaluated accordingly. The battery delivers a good reversible charge-discharge capacity close to 140 mAh g-1 at 1 C rate and 25°C with only 0.022% per cycle decay after 200 cycles. …”
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26969
Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract
Published 2013-01-01“…The extract also exhibited antiplatelet aggregation ability, antibacterial activity, and antiproliferative effect against cancer cell lines: Caco-2, HCT-15, and MCF-7. Phytochemical evaluation of the extract revealed the occurrence of total phenolics (49.91 mg GAE/g extract), total flavonoids (26.6 mg RE/g extract), and condensed tannins (0.7 mg TAE/g extract). …”
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26970
The Role of Neurokinin-1 Receptor in the Microenvironment of Inflammation and Cancer
Published 2012-01-01“…Recently, it has become apparent that SP can induce tumor cell proliferation, angiogenesis, and migration via the NK-1 receptor, and that the SP/NK-1 receptor complex is an integral part of the microenvironment of inflammation and cancer. …”
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26971
Mechanisms of Copper-Induced Autophagy and Links with Human Diseases
Published 2025-01-01“…However, excess intracellular copper can induce cell death due to its potential to catalyze the generation of reactive oxygen species, thus copper homeostasis is strictly regulated. …”
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26972
Application Strategies of Super-Enhancer RNA in Cardiovascular Diseases
Published 2025-01-01“…These regions play a pivotal role in regulating genes involved in cell identity and disease progression. This article reviews the characteristics of seRNAs, their expression patterns, and regulatory mechanisms in the cardiovascular system. …”
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26973
Modern approaches to artificial gene synthesis: aspects of oligonucleotide synthesis, enzymatic assembly, sequence verification and error correction
Published 2018-08-01“…Development of system biology has allowed forming a deeper understanding of the functions and relationship of natural biological models, as well as of the computational models describing processes at the cell and system levels. Combination of these factors has created an opportunity for conscious changes of natural biological systems. …”
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26974
Immunomodulatory Properties of HLA-G in Infectious Diseases
Published 2014-01-01“…The relevance of studies on HLA-G expression lies in the well known inhibitory effect of this molecule on all cell types involved in innate and adaptive immunity, favoring escape from immune control. …”
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26975
Stevens-Johnson Syndrome and Erythema Multiforme Induced by Imiquimod 5% Cream
Published 2025-01-01“… Introduction: Topical imiquimod is a safe and effective treatment for actinic keratoses, superficial basal cell carcinomas and anogenital warts. The treatment is commonly associated with local inflammatory reactions, while systemic side effects are rare and generally mild. …”
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26976
Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer
Published 2015-01-01“…Preclinical studies in animal models suggest that multitargeted tyrosine kinase inhibitors (TKIs), including FGFR inhibitor, suppress tumor cell proliferation and delay tumor progression. Several TKIs are now being evaluated in clinical trials as treatment for metastatic or unresectable GC harboring FGFR2 amplification.…”
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26977
Proteomics of the Dark-Ventral-Patch Sexual Signal in Male Red Deer
Published 2025-01-01“…In this study, we used a shotgun proteomic approach to investigate whether the ventral patch hair retains proteins on its surface that could reveal metabolic and cell-signaling adaptations potentially related to reproductive activity. …”
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26978
miR-468-3p suppresses osteogenic differentiation of BMSCs by targeting Runx2 and inhibits bone formation
Published 2024-12-01“…Abstract An improved understanding of the molecular actions underpinning bone marrow mesenchymal stem cell (BMSC) differentiation could highlight new therapeutics for osteoporosis (OP). …”
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26979
An atlas of metabolites driving chemotaxis in prokaryotes
Published 2025-02-01“…Our analysis reveals that (i) not all chemical classes trigger chemotaxis equally, in particular, amino acids and benzenoids are much stronger attractants than carbohydrates; (ii) over one-quarter of attractants tested are not used for growth but solely act as chemotactic signals; (iii) the prokaryote’s origin matters, as terrestrial strains respond to 50% more chemicals than those originating from human or marine biomes; (iv) repellents affect cell behaviour at concentrations 10-fold higher than attractants; (v) the effect of large molecules and the behaviour of bacteria other than Proteobacteria have been largely overlooked. …”
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26980
La pensée de Carl Gustav Jung et les courants néo-gnostiques de la première moitié du xxe siècle
Published 2011-12-01“…Elle reconstitue au préalable l’histoire de la réception d’idées gnostiques dans l’espace germanique aux XIXe et XXe siècles, puis situe l’approche qu’en propose Jung par rapport à celle d’autres auteurs contemporains et acteurs de cette « récidive gnostique» (Blumenberg) dans la première moitié du XXe siècle, qui privilégie les thèmes et mythes de la chute, du monde créé par un démiurge mauvais, de l’homme comme étranger dans ce monde… L’étude interroge ensuite la construction des notions les plus originales de la théorie jungienne du psychisme (l’inconscient collectif, l’anima, le Soi) dans leur relation à des représentations issues de cette tradition. …”
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