Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia by Jing Wang, Terry W. Wright, Francis Gigliotti

“…Pneumocystis is an opportunistic fungal respiratory pathogen that causes life-threatening pneumonia (Pcp) in patients suffering from defects in cell-mediated immunity, including those with acquired immunodeficiency syndrome (AIDS) and immunosuppression secondary to chemotherapy or organ transplantation. …”
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The Effects of 1-Methylcyclopropene in the Regulation of Antioxidative System and Softening of Mango Fruit during Storage by Li Li, Changbao Li, Jian Sun, Jinfeng Sheng, Zhugui Zhou, Ming Xin, Ping Yi, Xuemei He, Fengjin Zheng, Yayuan Tang, Jiemin Li, Jie Tang

“…The fruit treated with 1-MCP displayed significantly inhibited activation of enzymes on the cell wall, i.e., pectin esterase (PE), endo-1,4-β-d-glucanase (EGase), exopolygalacturonase (exo-PG), and endopolygalacturonase (endo-PG), during storage. …”
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Time–Course Analysis of the Onset and Progression of Cuticle Cracking in Fruits of Cherry Tomato Cultivar ‘Nene’ by Ryosuke Hosoi, Kazuo Ikeda, Takashi Nishizawa, Tomoyuki Nabeshima

“…Several fruit characteristics—including the fruit weight, cuticular membrane deposition, and epidermal cell morphology—were analyzed alongside environmental factors to identify the conditions under which cuticular crack occurs. …”
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Isolation and Characterization of Pectic Polysaccharide Fraction from In Vitro Suspension Culture of Fumaria officinalis L. by Manol Ognyanov, Yordan Georgiev, Nadezhda Petkova, Ivan Ivanov, Ivelina Vasileva, Maria Kratchanova

“…The high amount of 4-L-hydroxyproline (11.7% of total protein) and the specific positive reaction to Yariv’s phenylglycoside reagent indicated the presence of an arabinogalactan protein in the cell walls. The functional properties of the polysaccharide fraction were evaluated, as it possessed better water-holding capacity than oil-holding capacity. …”
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Vascularization of Nanohydroxyapatite/Collagen/Poly(L-lactic acid) Composites by Implanting Intramuscularly In Vivo by Hai Wang, Xiao Chang, Guixing Qiu, Fuzhai Cui, Xisheng Weng, Baozhong Zhang, Xiaojie Lian, Zhihong Wu

“…It could repair small sized bone defects, but they were restricted to repair a large defect due to the lack of oxygen and nutrition supply for cell survival without vascularization. The aim of the present study was to investigate whether nHAC/PLA composites could be vascularized in vivo. …”
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Dynamically induced spatial segregation in multispecies bacterial bioconvection by Oscar Gallardo-Navarro, Rinat Arbel-Goren, Elias August, Gabriela Olmedo-Alvarez, Joel Stavans

“…Under oxygen gradients, many bacterial species swim towards air-liquid interfaces in auto-organized, directional bioconvective flows, whose spatial scales exceed the cell size by orders of magnitude. Here we show that multispecies bacterial suspensions undergoing oxytactic-driven bioconvection exhibit dynamically driven spatial segregation, despite the enhanced mixing of bioconvective flows, and the fact that these species coexist in their natural habitat. …”
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Biosurfactant-Producing Lactobacilli: Screening, Production Profiles, and Effect of Medium Composition by Eduardo J. Gudiña, José A. Teixeira, Lígia R. Rodrigues

“…The highest biosurfactant production (excreted and cell-bound biosurfactants) was achieved with Lactobacillus paracasei ssp. paracasei A20, a strain isolated from a Portuguese dairy plant, with a decrease in the surface tension of 6.4 mN m−1 and 22.0 mN m−1, respectively. …”
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Stathmin 1 expression in neuroendocrine and proliferating prostate cancer by Yingli Shi, Yunshin A. Yeh, Siyuan Cheng, Xin Gu, Shu Yang, Lin Li, Nazih P. Khater, Susan Kasper, Xiuping Yu

“…We found that elevated STMN1 expression correlated with high Gleason Scores, increased cell proliferation, and poor clinical outcomes in PCa patients. …”
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Evaluation of a flow cytometry-based surrogate assay (FlowSA) for the detection of SARS-CoV-2 in clinical samples by Vinit Upasani, Marjolein Knoester, Daniele Pantano, Lili Gard, Jolanda M. Smit, Bernardina T.F. van der Gun, Adriana Tami, Izabela A. Rodenhuis-Zybert

“…Notably, FlowSA identified the presence of infectious SARS-CoV-2 in biological specimens that scored negative for cytopathic effect (CPE) in cell culture and would otherwise be considered negative. …”
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Origanum majorana Essential Oil Lacks Mutagenic Activity in the Salmonella/Microsome and Micronucleus Assays by Andrea dos Santos Dantas, Luiz Carlos Klein-Júnior, Miriana S. Machado, Temenouga N. Guecheva, Luciana D. dos Santos, Régis A. Zanette, Fernanda B. de Mello, João Antonio Pêgas Henriques, João Roberto Braga de Mello

“…For the in vitro mammalian cell micronucleus test, V79 Chinese hamster lung fibroblasts were used. …”
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Familial Russell–Silver Syndrome like Phenotype in the PCNA Domain of the CDKN1C Gene, a Further Case by A. H. Sabir, G. Ryan, Z. Mohammed, J. Kirk, N. Kiely, M. Thyagarajan, T. Cole

“…A maternally inherited pathogenic heterozygous CDKN1C variant was found in the PCNA (proliferating cell nuclear antigen) domain. Mutations of the PCNA domain of the CDKN1C gene are known to be associated with IMAGe syndrome thus with adrenal disease, although neither affected patient in our case had evidence of adrenal dysfunction. …”
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Adjusting Hirshfeld charge of TEMPO catholytes for stable all-organic aqueous redox flow batteries by Gonggen Tang, Wenyi Wu, Yahua Liu, Kang Peng, Peipei Zuo, Zhengjin Yang, Tongwen Xu

“…Finally, a TPP-TEMPO/BTMAP-Vi (1,1′-bis[3-(trimethylammonio)propyl]-4,4′-bipyridinium tetrachloride) cell achieves a capacity density of ~12 Ah L− 1 and a low capacity fade rate of 0.0018% per cycle (or 0.0067% per hour).…”
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Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana by Sayo Kashiwagi, Isao Kuraoka, Yoshie Fujiwara, Kenichi Hitomi, Quen J. Cheng, Jill O. Fuss, David S. Shin, Chikahide Masutani, John A. Tainer, Fumio Hanaoka, Shigenori Iwai

“…ApPolη shares sequence homology with HsPolη and contains domains for binding ubiquitin and proliferating cell nuclear antigen. Sun-induced UV does not penetrate Alvinella's environment; however, this novel DNA polymerase catalyzed efficient and accurate TLS past CPD, as well as 7,8-dihydro-8-oxoguanine and isomers of thymine glycol induced by reactive oxygen species. …”
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Radix Codonopsis: a review of anticancer pharmacological activities by Cai-Yue Liu, Zheng Li, Fan-E. Cheng, Yi Nan, Yi Nan, Wei-Qiang Li, Wei-Qiang Li

“…Studies have identified key active components such as luteolin, stigmasterol, polyacetylenes, lobetyolin, and glycitein, which exhibit anti-tumor properties through mechanisms like inhibiting cancer cell growth and proliferation, suppressing epithelial-mesenchymal transition (EMT), and inducing apoptosis. …”
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Cholesterol Targeted Catalytic Hydrogel Fueled by Tumor Debris can Enhance Microwave Ablation Therapy and Anti‐Tumor Immune Response by Lin Shen, Zhijuan Yang, Yi Zhong, Yanran Bi, Junchao Yu, Qinwei Lu, Yanping Su, Xiaoxiao Chen, Zhongwei Zhao, Gaofeng Shu, Minjiang Chen, Liang Cheng, Liangzhu Feng, Chenying Lu, Zhuang Liu, Jiansong Ji

“…In both in vitro and in vivo HCC models, DA‐COD‐OD‐HCS effectively released COD, degraded cholesterol, and induced tumor cell ferroptosis, enhancing the antitumor immune response. …”
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Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade by Avantika Chenna, Venu Madhav Konala, Subhasish Bose, Sasmit Roy, Bhaskar Reddy Madhira, Vijay Gayam, Srikanth Naramala, Sreedhar Adapa

“…Membrane-bound angiotensin-converting enzyme 2 (ACE2) has been implicated as the gateway for viral entry into the human cell in causing the infection. The factors contributing to acute kidney injury are diuretics, iodinated contrast administration, hemodynamic instability apart from ACE inhibitors, and angiotensin receptor blockers. …”
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Assessing spacer acquisition rates in E. coli type I-E CRISPR arrays by Luke J. Peach, Haoyun Zhang, Brian P. Weaver, James Q. Boedicker, James Q. Boedicker

“…Prolonged Cas1–Cas2 expression produced fewer new spacers per cell on average than predicted by the model. Subsequent experiments revealed that this was due to a mean fitness reduction linked to array-expanded populations. …”
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Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis by Lucía Arévalo-Híjar, Miguel Ángel Aguilar-Luis, Stefany Caballero-García, Néstor Gonzáles-Soto, Juana Del Valle-Mendoza

“…None of the extracts exhibited toxicity against the cell lines under low concentrations.…”
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OCH Ameliorates Bone Marrow Failure in Mice via Downregulation of T-Bet Expression by Xiaohong Qiao, Xiaotian Xie, Wei Shi, Jinqing Tang, Yuexia Shao, Fuxing Li

“…In addition, OCH treatment increased NKT cell fractions of bone marrow and the colonies of CFU-GM. …”
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Metallic perforated plate lattices with superior buckling strength by Lei Zhang, Mingpei Cang, Junhao Ding, Winston Wai Shing Ma, Xiangyang Zhu, Yang Lu, Xu Song, Huachen Cui, Michael Yu Wang

“…Plate lattices possess promising stiffness and yielding strength; however, their closed-cell topology dramatically increases the manufacturing difficulty. …”
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