Computational problems of analysis of short next generation sequencing reads by R. te Boekhorst, F. M. Naumenko, N. G. Orlova, E. R. Galieva, A. M. Spitsina, I. V. Chadaeva, Y. L. Orlov, I. I. Abnizova

“…Short read next generation sequencing (NGS) has significant impacts on modern genomics, genetics, cell biology and medicine, especially on meta-genomics, comparative genomics, polymorphism detection, mutation screening, transcriptome profiling, methylation profiling, chromatin remodelling and many more applications. …”
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Basis of single-seed formation in chestnut: cytomorphological observations reveal ovule developmental patterns of Castanea henryi by Qi Qiu, Xiaoming Tian, Guolong Wu, Juntao Wu, Deyi Yuan, Xiaoming Fan

“…Approximately 53.53% of the ovules in the pollinated treatment developed normally, while only 16.55% of the ovules in the unpollinated treatment developed into mature embryo sacs with a seven-cell, eight-nucleated structure. Failure to form mature embryo sacs and the abnormal divisions of the zygote, respectively, were the reasons for the pre- and post-fertilization ovule failures. …”
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The Role of Virtual Cystoscopy, after Multidetector Computed Tomography Imaging Reconstruction without the Use of Contrast Medium, in the Diagnosis and Evaluations of Bladder Tumor... by Kyriaki Kalokairinou, Achilles Ploumidis, Theodoros Kalogeropoulos, Lampros Vlachos, Kyriakos Stringaris, Ageliki Tavernaraki, Anastasios Thanos, Xenofon Papacharalampous, Vasilios Koutoulidis, Julien Letendre, Olivier Traxer, Athanasios Gouliamos

“…The pathological report revealed noninvasive transitional cell carcinomas in all cases. Conclusion. VC has promising results in detecting exophytic bladder lesions. …”
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Mosaic Trisomy 18 in a Five-Month-Old Infant by Ana Laura Fitas, Mafalda Paiva, Ana Isabel Cordeiro, Luís Nunes, Gonçalo Cordeiro-Ferreira

“…Individuals with mosaic trisomy 18, only approximately 5% of all trisomy 18 cases, carry both a trisomy 18 and an euploid cell line. Their clinical findings are highly variable, from the absence of dysmorphic features to the complete trisomy 18 syndrome. …”
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Biomimetic Versatile Anisotropic, Electroactive Cellulose Hydrogel Scaffolds Tailored from Fern Stem Serving as Nerve Conduit and Cardiac Patch by Qinghui Liang, Shuhui Chen, Shaofeng Hua, Weihong Jiang, Jiamian Zhan, Chunyi Pu, Rurong Lin, Yutong He, Honghao Hou, Xiaozhong Qiu

“…Both nerve and cardiac tissues exhibit structural anisotropy and electrophysiological activity, providing a wide range of biophysical cues for cell and tissue repair. However, balancing microstructural anisotropy, electroactivity, and biocompatibility is challenging. …”
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Salivary biomarkers: A promising avenue for advancing oral cancer detection by Yuvashree Chandrasekaran, L. Kayal, N. Aravindha Babu, Mukesh Kumar Dharmalingam Jothinathan, Archana Behera

“…Salivary cancer biomarkers are crucial for the earliest identification of oral carcinoma, particularly oral squamous cell carcinoma (OSCC). This article will address recent progress in detecting saliva biomarkers including human DNA, mRNA and proteins that can be of diagnostic value in cancer. …”
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N-Cadherin promotes cardiac regeneration by potentiating pro-mitotic β-Catenin signaling in cardiomyocytes by Yi-Wei Tsai, Yi-Shuan Tseng, Yu-Shuo Wu, Wei-Lun Song, Min-Yi You, Yun-Chia Hsu, Wen-Pin Chen, Wei-Han Huang, Jia-Ci Chng, Chai-Ling Lim, Ke-Hsuan Wei, Shih-Lei Ben Lai, Wen-Chih Lee, Kai-Chien Yang

“…N-Cadherin knockdown reduces, whereas overexpression increases, the proliferation activity of neonatal mouse CMs and human induced pluripotent stem cell-derived CMs. Mechanistically, N-Cadherin binds and stabilizes pro-mitotic transcription regulator β-Catenin, driving CM self-renewal. …”
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Human Serum Eye Drops in Eye Alterations: An Insight and a Critical Analysis by Maria Rosaria De Pascale, Michele Lanza, Linda Sommese, Claudio Napoli

“…Human serum contains a physiological plethora of bioactive elements naturally released by activated platelets which might have a significant effect on the regeneration of corneal layers by stimulating the cell growth. This mechanism supported the use of human serum eye drops in some ocular diseases associated with dystrophic changes and alterations of the tear film, such as persistent corneal epithelial defects and dry eye syndrome. …”
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A Hybrid Approach Incorporating WSO-HO and the Newton-Raphson Method to Enhancing Photovoltaic Solar Model Parameters Optimisation by Jeridi Ahmed, Moulahi Mohamed Hedi, Khaterchi Hechmi, Zaafouri Abderrahmen

“…The effectiveness of the WSO-HO algorithm was rigorously evaluated through intensive testing on three different solar panels, including the RTC France solar cell using the single diode model (SDM) and the double diode model (DDM), over 30 iterations. …”
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Exploring glycolytic enzymes in disease: potential biomarkers and therapeutic targets in neurodegeneration, cancer and parasitic infections by Maura Rojas-Pirela, Diego Andrade-Alviárez, Verónica Rojas, Miguel Marcos, Daniel Salete-Granado, Marirene Chacón-Arnaude, María Á. Pérez-Nieto, Ulrike Kemmerling, Juan Luis Concepción, Paul A. M. Michels, Wilfredo Quiñones

“…It has great relevance at a physiological level because it is responsible for generating ATP in the cell through the conversion of glucose into pyruvate and reducing nicotinamide adenine dinucleotide (NADH) (that may be fed into the electron chain in the mitochondria to produce additional ATP by oxidative phosphorylation), as well as for producing intermediates that can serve as substrates for other metabolic processes. …”
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Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer by A. K. M. Firoj Mahmud, Dina Gamaleldin Mansour Aly, Yelin Zhao, Mikael Benson, Martin Smelik, Oleg Sysoev, Hui Wang, Xinxiu Li

“…Differential expression of these genes was observed across various cell types in PC, indicating their involvement in the tumor microenvironment. …”
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New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation by Mohamed A. Abdelgawad, Mohammad M. Al-Sanea, Mohamed A. Zaki, Enas I. A. Mohamed, Shabana I. Khan, Babu L. Tekwani, Amar G Chittiboyina, Ikhlas A Khan, Tarfah Al-Warhi, Nada Aljaeed, Ohoud J. Alotaibi, Abdulsalam A. M. Alkhaldi, Heba A. H. Elshemy

“…The biological evaluation of all target compounds as potential antimalarial, antileishmanial, antitrypanosomal, and antimicrobial agents was performed by various well-established cell-based methods. Results. Compounds 6d and 5a showed promising biological screening data. …”
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Protective effects of olive oil phenolics oleuropein and hydroxytyrosol against hydrogen peroxide-induced DNA damage in human peripheral lymphocytes by Zorić Nataša, Kopjar Nevenka, Rodriguez Jadranka Vuković, Tomić Siniša, Kosalec Ivan

“…Pretreatment of human lymphocytes with each of the substances for 120 min produced a dose-dependent reduction of primary DNA damage in the tested cell type. Hydroxytyrosol showed a better protective effect against H2O2-induced DNA breaks than oleuropein which could be associated with their free radical-scavenging efficacy.…”
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A Linear Parameter Varying Control Approach for DC/DC Converters in All-Electric Boats by Soroush Azizi, Mohammad Hassan Asemani, Navid Vafamand, Saleh Mobayen, Mohammad Hassan Khooban

“…In this paper, a suitable controller for the energy resources of an EB which consists of a 5 kW solar power plant, 5 kW fuel cell, and 2 kW battery package is designed based on the linear parameter varying (LPV) controller design approach. …”
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A root system architecture regulator modulates OsPIN2 polar localization in rice by Yong Li, Meiyan Ren, Yunrong Wu, Lingling Wang, Keju Zhao, Hongsheng Gao, Mengzhen Li, Yu Liu, Jianshu Zhu, Jiming Xu, Xiaorong Mo, Zhongchang Wu, Chungui Lu, Shaojian Zheng, Chuanzao Mao

“…OsGLS1 encodes a RING finger E3 ubiquitin ligase mainly localizing at the basal plasma membrane (PM) in several root cell types when phosphorylated on its Ser-30 residue. …”
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Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein by Yanxiao Han, John R.D. Dawson, Kevin R. DeMarco, Kyle C. Rouen, Khoa Ngo, Slava Bekker, Vladimir Yarov-Yarovoy, Colleen E. Clancy, Yang K. Xiang, Surl-Hee Ahn, Igor Vorobyov

“…Summary: G protein-coupled receptors (GPCRs) and G proteins transmit signals from hormones and neurotransmitters across cell membranes, initiating downstream signaling and modulating cellular behavior. …”
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Laparoscopic Resection of Pancreatic Tail Solid Pseudopapillary Tumour in a Young Male by W. G. P. Kanchana, R. A. A. Shaminda, K. B. Galketiya, V. Pinto, D. Walisinghe, S. Wijetunge, R. Heendeniya

“…Histology revealed a clear cell variant of solid pseudopapillary neoplasm with steatotic pattern. …”
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Peptide–Polymer Conjugates: A Promising Therapeutic Solution for Drug-Resistant Bacteria by Xuqiu Shen, Yiyin Zhang, Qijiang Mao, Zhengze Huang, Tingting Yan, Tianyu Lin, Wenchao Chen, Yifan Wang, Xiujun Cai, Yuelong Liang

“…Antimicrobial peptide (AMP) is widely used to prevent such circumstances, for the positively charged AMPs can kill drug-resistant bacteria by destroying negatively charged bacterial cell membrane, and has excellent antibacterial efficiency and low drug resistance. …”
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Strain-specific effects of Akkermansia muciniphila on the regulation of intestinal barrier by Yang Liu, Qing Liu, Chengcheng Zhang, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

“…The role of these surface proteins in intestinal barrier regulation was further verified by strain-comparative experiments in animal and cell models and surface protein removal trials. This study confirmed the different effects of A. muciniphila strains on gut barrier modulation and provided molecular and genetic targets for the screening of A. muciniphila strains with superior protection against gut barrier dysfunction.…”
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Microbial Biomass as a Bioresource of Functional Food Ingredients: A Review by Elena M. Serba, Tatyana V. Yuraskina, Liubov V. Rimareva, Polina Yu. Tadzibova, Elena N. Sokolova, Galina S. Volkova

“…Most studies concentrated on the chitin-glucan-mannan complex of cell walls and protoplasmic biovaluable protein. …”
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