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26481
Mitochondrial Dysfunction: A Basic Mechanism in Inflammation-Related Non-Communicable Diseases and Therapeutic Opportunities
Published 2013-01-01“…These organelles act to supply the cell with ATP and to synthesise key molecules in the processes of inflammation, oxidation, and metabolism. …”
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26482
Telomere Biology: Key to unlocking the fountain of youth…A Systematic Review.
Published 2024-11-01“…Deterioration of physiological functions is typically associated with ageing process.This often manifests as various diseases which eventually creates a burden on health infrastructure.Telomere attrition is a phenomenon which involves shortening of telomeres with each cycle of cell division.The phenomenon of “Telomere Attrition” is a “Bi edged sword” as while being a protective shield for the genome on one hand, it also is the cause of many senility related degenerative disorders. …”
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26483
Effect of High Hydrostatic Pressure Processing Strategies on Retention of Antioxidant Phenolic Bioactives in Foods and Beverages – a Review
Published 2016-12-01“…HPE enhances mass transfer rates, increases cell permeability, increases diffusion of phenolics and retains higher levels of bioactive compounds. …”
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26484
Methylcobalamin protects against liver failure via engaging gasdermin E
Published 2025-01-01“…Abstract Gasdermin E (GSDME) is a pyroptotic cell death effector and a promising target for pyroptotic tissue injury. …”
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26485
Electrolyte design for reversible zinc metal chemistry
Published 2025-01-01“…Building upon the near-unity CE, an anode-free cell with ZnI2 cathode can stably run more than 1000 cycles under practical conditions with minimal capacity loss. …”
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26486
Hypoglycemic effects of naturally processed Polygonum multiflorum extract in KK CgAy/J mice and its mechanism of action
Published 2022-09-01“…The mechanism was explored with ELISA and Western blotting and results suggested that the effect was through maintaining β-cell function.…”
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26487
New perspectives on DNA methylation modifications in ocular diseases
Published 2025-02-01“…DNA methylation can regulate gene expression, thereby affecting cell function and signal transduction. Ophthalmic diseases are a kind of complex diseases, and their pathogenesis involves many factors such as genetic, environmental and individual differences. …”
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26488
Research Progress on the Role of Inflammasomes in Kidney Disease
Published 2020-01-01“…Inflammasomes are multimeric complexes composed of cytoplasmic sensors, apoptosis-associated speck-like protein containing a caspase activation and recruitment domain (ASC or PYCARD), and procaspase-1 and play roles in regulating caspase-dependent inflammation and cell death. Inflammasomes are assembled by sensing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) and initiate inflammatory responses by activating caspase-1. …”
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26489
A Turner Syndrome Patient Carrying a Mosaic Distal X Chromosome Marker
Published 2014-01-01“…Conventional karyotyping revealed a mosaic Turner syndrome karyotype with a cell line containing a small marker of X chromosome origin. …”
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26490
Cytotoxicity and Antibacterial Activity of Mineral Trioxide Aggregate Cement with Radiopacity Introduced by ZrO2
Published 2022-01-01“…Then, the cytotoxic action of the cements was evaluated by applying a reference L-929 cell line. The conditions of the culture upon contact with the tested materials or with extracts from the cements were assessed using image analysis or an MTT colorimetric assay. …”
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26491
The Endocannabinoid System in the Postimplantation Period: A Role during Decidualization and Placentation
Published 2013-01-01“…Additionally, endocannabinoid’s plasmatic levels were found to fluctuate during normal gestation and to induce decidual cell death and disturb normal placental development. …”
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26492
Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis
Published 2015-01-01“…However, the density of corneal endothelial cell was less than the measurable range and CMV was detected by PCR of the aqueous humor. …”
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26493
Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria
Published 2016-01-01“…The infection of human macrophages by pathogenic bacteria induces different signaling pathways depending on the type of cellular receptors involved in the microorganism entry and on their mechanism(s) of survival and replication in the host cell. It was reported that Stat proteins play an important role in this process. …”
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26494
Effect of alcoholic extract of tarantula cubensis (theranekron<sup>®</sup>) on serum thiobarbituric acid-reactive species concentrations in sheep
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26495
Developing an alternative medium for in-space biomanufacturing
Published 2025-01-01“…Our results show that RPET S6 could directly utilize regolith simulant particles as mineral replacements, while the addition of anaerobically pretreated fecal waste synergistically supported its cell growth. Additionally, lycopene production using AF under microgravity conditions achieved levels comparable to those on Earth. …”
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26496
Preparation and Stability of Inorganic Solidified Foam for Preventing Coal Fires
Published 2014-01-01“…The outcomes indicated that calcium fluoroaluminate could enhance the stability coefficient of ISF and compact hydration products formed in cell wall of ISF; naturally, the stability principle of ISF was proved right. …”
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26497
De novo biosynthesis of nylon 12 monomer ω-aminododecanoic acid
Published 2025-01-01“…Here, we show the development of an engineered Escherichia coli cell factory capable of biosynthesizing the nylon 12 monomer, ω-aminododecanoic acid (ω-AmDDA), from glucose. …”
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26498
Betalains protect various body organs through antioxidant and anti-inflammatory pathways
Published 2024-05-01“…This review article described the in-vivo antioxidant and anti-inflammatory activities of betalains in various cell-line or animal models. A comprehensive discussion has been provided on the mechanism of action of betalains in protecting various body organs, including cardio-protective effect, hepato-protective ability, renal protection capacity, repro-protective ability, neuro-protective effect, lung protection, and gut protection ability. …”
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26499
Essential functions, syntheses and detection of sialyl Lewis X on glycoproteins
Published 2023-02-01“…It is widely acknowledged that sialyl Lewis X (sLeX), the composition and linkage of which are N-acetylneuraminic acid (Neu5Ac) α2-3 galactose (Gal) β1-4 [fucose (Fuc) α1-3] N-acetylglucosamine, is usually attached to the cell surface. It presents as a terminal structure on either glycoproteins or glycolipids and has been demonstrated to be related to various biological processes, such as fertilization and selectin binding. …”
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26500
Assessing the Impact of Isoniazid Preventive Therapy (IPT) on Tuberculosis Incidence and Predictors of Tuberculosis among Adult Patients Enrolled on ART in Nekemte Town, Western Et...
Published 2019-01-01“…Tuberculosis incidence among the Isoniazid treated group was 1.98 per 100 person-years and 4.52 per 100 person-years in the untreated group. CD4 cell count, clinical staging, body mass index (BMI), not using cotrimoxazole, body weight, and functional status were significant predictors of tuberculosis risk. …”
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