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26381
Failure Modes in Concrete Repair Systems due to Ongoing Corrosion
Published 2017-01-01“…While the development of the corrosion cell is difficult to control, the damage can be possibly delayed and controlled by use of a suitable repair material. …”
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26382
Impact of artificial meat as novel food: controversies and future perspectives
Published 2023-04-01“…Artificial meat production starts from an isolated muscle cell taken from a live animal and then cultivated to form slices of artificial meat with taste, texture, and look similar to regular meat. …”
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26383
A Comparison of Off-Grid-Pumped Hydro Storage and Grid-Tied Options for an IRSOFC-HAWT Power Generator
Published 2017-01-01“…An Internal Reforming Solid Oxide Fuel Cell (IRSOFC) is modeled thermodynamically; a Horizontal Axis Wind Turbine (HAWT) is designed; the combined IRSOFC-HAWT system should create a reliable source of electricity for the demand of a village located in Manjil, Iran. …”
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26384
Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease
Published 2015-01-01“…Although the exact underlying mechanisms leading to neural cell death in this disease remains unknown, the genetic causes are often established. …”
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26385
Microglia and Synapse: Interactions in Health and Neurodegeneration
Published 2013-01-01“…The surveillance of neuronal circuits executed by each microglial cell overseeing its territory occurs in the form of regular, dynamic interactions. …”
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26386
The Mammary Gland Carcinogens: The Role of Metal Compounds and Organic Solvents
Published 2013-01-01“…The four most predominant mechanisms for metal carcinogenicity include (1) interference with cellular redox regulation and induction of oxidative stress, (2) inhibition of major DNA repair, (3) deregulation of cell proliferation, and (4) epigenetic inactivation of genes by DNA hypermethylation. …”
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26387
A Review on Factors Influencing the Mismatch Losses in Solar Photovoltaic System
Published 2022-01-01“…Solar photovoltaic systems have made topical advances in the use of highly effective solar cell materials to achieve high efficiency. In this analysis, performance parameters are influenced by the internal and external conditions of the solar photovoltaic systems and they lead to an increase in the loss of the system. …”
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26388
Photochemical and photobiological properties of furocoumarins and homologues drugs
Published 1999-01-01“…Their therapeutic effectiveness is connected to the lesions they induce to various cell components, membranes, ribosomes, mitochondria, and in particular to DNA, damaged by formation of monofunctional adducts and of inter-strand cross-links (ISC). …”
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26389
Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance
Published 2025-02-01“…Future directions include developing next-generation AR antagonists, identifying AR-related biomarkers for personalized therapy, and exploring combinations with immune checkpoint inhibitors. Additionally, basal cell-lumen-derived organoids provide innovative models that can enhance understanding and treatment strategies in prostate cancer.…”
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26390
Aldosterone and Its Blockade: A Cardiovascular and Renal Perspective
Published 2006-01-01“…A pathophysiological action of aldosterone involves development of extracellular matrix and fibrosis, inflammation, stimulation of reactive oxygen species production, endothelial dysfunction, cell growth and proliferation. Many studies showed local extra-adrenal production of aldosterone in brain blood vessel, and the heart, which contribute in an important manner to the pathological actions of this mineralocorticoid.Several studies such as RALES, EPHESUS, 4E and others, recently showed that mineralocorticoid-receptor (MR) antagonists, alone or in combination with ACE inhibitors or ARBs, reduced the risk of progressive target organ damage and hospitalization in patients with hypertension and heart failure. …”
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26391
Du discours au comportement. La validité de la théorie des instances
Published 2025-02-01“…Sans oublier la question complexe de l’évaluation psychothérapeutique, un itinéraire marqué, dans le meilleur des cas, par des étapes de progression du sujet manifestant des instances énonciatives successives tendant vers celle qui signe la guérison.…”
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26392
Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus
Published 2017-01-01“…Recent evidence suggests that LC neurons accumulate aberrant tau species for decades before frank LC cell body degeneration occurs in AD, suggesting that a therapeutic window exists. …”
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26393
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26394
Autophagy in brain tumors: molecular mechanisms, challenges, and therapeutic opportunities
Published 2025-01-01“…Autophagy plays a crucial role in the development of diseases, particularly human cancers, with actions that can either promote survival or induce cell death. However, brain tumors contribute to high levels of both mortality and morbidity globally, with resistance to treatments being acquired due to genetic mutations and dysregulation of molecular mechanisms, among other factors. …”
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26395
The Role of Oxidative Stress in the Aging Process
Published 2010-01-01“…Although reactive oxygen species (ROS) are predominantly implicated in causing cell damage, they also play a major physiological role in several aspects of intracellular signaling and regulation. …”
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26396
Microevolution during Chronic Infection May Lead T. asahii to Coexist with the Host
Published 2024-01-01“…Two T. asahii strains were isolated from a chronic trichosporonosis patient between a 15-year interval, and the microevolutionary changes were compared by the immune response of dendritic cell (DC), mice survival model, and transcriptome sequencing analysis. …”
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26397
Bioartificial Liver Support
Published 2001-01-01“…The optimal source for the hepatocytes is an area of debate; however, a genetically engineered cell line may provide optimal function. Novel three-dimensional matrices that anchor the hepatocytes are being designed to mimic architectural features of the normal liver. …”
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26398
THE ROLE OF ANTIBIOTICS IN TREATING SALIVARY GLAND INFECTIONS
Published 2024-12-01“…Antibiotics work through various mechanisms, including inhibiting bacterial cell wall synthesis, inhibiting protein synthesis, or interfering with essential bacterial functions. …”
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26399
Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?
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26400
Lipopeptide adjuvants for antibiotics and vaccines: the future step in the fight against multidrug-resistant and extensively drug-resistant pathogens
Published 2024-04-01“…Lipopeptides are molecules of choice because of their ability to activate specific cell surface receptors, penetrate the outer membrane of GNB, safety and ease of synthesis. …”
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