Analysis of Role of Haematological Parameters in Diagnosis of Grampositive and Gram-negative Urinary Tract Infection: A Case-control Study by Sudha Srinivasan, Ayeesha Sithika Thajudeen, Kundhavai Chandrasekaran, Vijayashree Raghavan, D Roshini

“…Haematological parameters such as Haemoglobin (Hb), White Blood Cell Count (WBC), platelet count, Mean Platelet Volume (MPV), Red Cell Distribution Width (RDW), Platelet Distribution Width (PDW) and Plateletcrit (PCT) were analysed using an automated haematology analyser. …”
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Usability and Usefulness of a Symptom Management Coaching System for Patients With Cancer Treated With Immune Checkpoint Inhibitors: Comparative Mixed Methods Study by Savannah Lucia Caterina Glaser, Itske Fraterman, Noah van Brummelen, Valentina Tibollo, Laura Maria Del Campo, Henk Mallo, Sofie Wilgenhof, Szymon Wilk, Vitali Gisko, Vadzim Khadakou, Ronald Cornet, Manuel Ottaviano, Stephanie Medlock

“…MethodsThis usability study was executed by interviewing participants with a melanoma or renal cell carcinoma diagnosis who have received immunotherapy and participants without direct experience with the targeted cancer types who have not received immunotherapy. …”
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Novel Role of Pin1-Cis P-Tau-ApoE Axis in the Pathogenesis of Preeclampsia and Its Connection with Dementia by Emmanuel Amabebe, Zheping Huang, Sukanta Jash, Balaji Krishnan, Shibin Cheng, Akitoshi Nakashima, Yitong Li, Zhixong Li, Ruizhi Wang, Ramkumar Menon, Xiao Zhen Zhou, Kun Ping Lu, Surendra Sharma

“…In the case of preE, proteinopathy/tauopathy may interrupt trophoblast differentiation and induce cell death, similar to the events occurring in neurons. …”
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Unlocking the potential of serious games for rehabilitation in low and middle-income countries: addressing potential and current limitations by Diriba Dereje, Diriba Dereje, Dheeraj Lamba, Teklu Gemechu Abessa, Teklu Gemechu Abessa, Chala Kenea, Chala Kenea, Cintia Ramari, Cintia Ramari, Muhammad Osama, Muhammad Osama, Oyéné Kossi, Oyéné Kossi, Paul Muteb Boma, Paul Muteb Boma, Jules Panda, Jules Panda, Jules Panda, Anna Kushnir, Anna Kushnir, Joanna Mourad, Joanna Mourad, Jean Mapinduzi, Jean Mapinduzi, Maryam Fourtassi, Kim Daniels, Kim Daniels, Judith Deutsch, Bruno Bonnechère, Bruno Bonnechère, Bruno Bonnechère

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HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma by Michal Frelich, Marek Bebej, Jan Pavlíček, Filip Burša, Vojtěch Vodička, Zdeněk Švagera, Adéla Kondé, Ondřej Jor, Markéta Bílená, Tereza Romanová, Peter Sklienka

“…Previous work has shown that higher levels of HMGB-1 are associated with a higher use of red blood cell transfusions. We conducted a retrospective analysis of previous prospective single-center study to assess the value of admission HMGB-1 levels in predicting activation of MTP in the emergency department. …”
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Molecular docking and dynamics studies to identify novel active compounds targeting potential breast cancer receptor proteins from an indigenous herb Euphorbia thymifolia Linn [ver... by ShamaPrasada K, Reshma Kumarchandra, Vasavi Kumblekar, K Sreedhara Ranganath Pai, Suman Manandhar, Sharada Rai, Rajeshwari Shastry

“…Therefore, the aim of the present study was to screen the phytoconstituents and identify the active compounds present in the methanolic extract of E. thymifolia (ME.ET) as ligands to inhibit human cancer cell lines with special reference to potential protein targets implicated in breast cancer using an In-silico approach. …”
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Diagnostic value of macular blood flow in normal tension glaucoma by A.Sh. Zagidullina, V.U. Galimova, A.I. Arslanova, A.R. Nugmanova

“…The severity of global losses of the retinal ganglion cell complex demonstrated a weak negative correlation (r=-0.464, p<0.01) with microcirculation density in the Fovea of the superficial retinal choroid plexus. …”
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Women and Politics in post devolution Scotland by Annie Thiec

“…La question de la représentation des femmes fut au cœur du débat public en Ecosse dans les années qui précédèrent la mise en œuvre du projet de dévolution du gouvernement de Tony Blair au lendemain de la victoire travailliste aux élections du 1er mai 1997, comme en témoignent les travaux de la Convention constitutionnelle écossaise dont les propositions donnèrent lieu à deux publications, la première en novembre 1990, ta seconde cinq ans plus tard, qui servit de base au projet du gouvernement travailliste.Contrairement à ce qui se produisit dans le reste du Royaume-Uni, le mouvement des femmes en Ecosse demeura très actif dans les années 80-90, manifestant, outre l’attention portée à des questions telles que celle des violences faites aux femmes, un intérêt particulier pour celle de leur représentation politique. …”
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ROS-induced cytosolic release of mitochondrial PGAM5 promotes colorectal cancer progression by interacting with MST3 by Shiyang Wang, Xi Wu, Wenxin Bi, Jiuzhi Xu, Liyuan Hou, Guilin Li, Yuwei Pan, Hanfu Zhang, Mengzhen Li, Sujuan Du, Mingxin Zhang, Di Liu, Shuiling Jin, Xiaojing Shi, Yuhua Tian, Jianwei Shuai, Maksim V. Plikus, Moshi Song, Zhaocai Zhou, Lu Yu, Cong Lv, Zhengquan Yu

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Semen quality and fertility effectiveness of cloned buffalo (Bubalus bubalis) bulls by Manoj Kumar Singh, Smiriti Gupta, Kanika Gandhi, S.S. Lathwal, Naresh L. Selokar

“…When these spermatozoa were subjected to a transcriptomics study, 27,481 transcripts were identified, out of which 18,703 transcripts were expressed commonly in both cloned and somatic cell donor bull’s spermatozoa. Only 566 transcripts were up- regulated, and 410 transcripts were down-regulated significantly (FC≥2; P<0.05) in clone bulls spermatozoa relative to somatic cell donor bulls spermatozoa. …”
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Comparison of centrifugal-membrane hybrid plasmapheresis and centrifugation therapeutic plasma exchange in hyperlipidemia by ZHANG Bin, WU Chunxi, ZHOU Yumeng, ZHOU Fang, YI Zhongmei

“…In the CMHP group, the plasma was separated by a blood cell separator and the plasma components were separated by a two-stage membrane plasma component separator. …”
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Insights into mungbean defense response to Cercospora leaf spot based on transcriptome analysis by Sukanya Inthaisong, Pakpoom Boonchuen, Tana Jaichopsanthia, Pongpan Songwattana, Apinya Khairum, Witsarut Chueakhunthod, Akkawat Tharapreuksapong, Panlada Tittabutr, Neung Teaumroong, Piyada Alisha Tantasawat

“…KEGG pathway analysis showed that these genes were represented in plant-pathogen interaction, the MAPK signaling pathway, plant hormone signal transduction, and cell wall component biosynthesis in response to the CLS infection specifically in SUPER5. …”
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Fast electrons produced by lower hybrid wave and effects on plasma–wall interactions by Hailong Lu, Nong Xiang, Zehua Qian, Hua Yang, Miaohui Li, Manni Jia, Gen Li, Zechen Wang, Changhao Deng, Jinjin Lu, Jiamin Long

“…In this work, particle-in-cell simulations are used to investigate the interactions between LHWs and electrons in front of the antenna, taking into account the realistic incident power spectra and localized field effects. …”
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Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding by Kyriakos Psarras, Nikolaos Symeonidis, Euthymia Vlachaki, Minas Baltatzis, Georgios Papatolios, Efstathios Pavlidis, Christina Mouratidou, Ioannis Venizelos, Theodoros Pavlidis, Athanasios Sakantamis, Christina Nikolaidou

“…The most common primary lymphomas of the gallbladder are MALT lymphomas and diffuse large B-cell lymphomas, although a variety of other histological types have been reported. …”
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Scrotal Swelling and Testicular Atrophy due to Schistosomiasis in a 9-Year-Old Boy: A Case Report by Peter F. Rambau, Alphonce Chandika, Philipo L. Chalya, Kahima Jackson

“…Major complications of S. maeametobium are chronic cystitis with squamous metaplasia with subsequent development of squamous cell carcinoma. Involvement of spinal cord causing paraplegia has been observed in S. haematobium. …”
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Suppression of epileptic seizures by transcranial activation of K+-selective channelrhodopsin by Xiaodong Duan, Chong Zhang, Yujie Wu, Jun Ju, Zhe Xu, Xuanyi Li, Yao Liu, Schugofa Ohdah, Oana M. Constantin, Yifan Pan, Zhonghua Lu, Cheng Wang, Xiaojing Chen, Christine E. Gee, Georg Nagel, Sheng-Tao Hou, Shiqiang Gao, Kun Song

“…Our approach for transcranial optogenetic inhibition of neural hyperactivity may be adapted for cell type-specific neuromodulation in both basic and preclinical settings.…”
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De novo design of protein minibinder agonists of TLR3 by Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King

“…Multivalent forms of both minibinders induce NF-κB signaling in TLR3-expressing cell lines, demonstrating that they may have therapeutically relevant biological activity. …”
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High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb by Tiffany J. Pan, Liron Pantanowitz, Kurt R. Weiss

“…The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. …”
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Morphologic Features of Extrahepatic Manifestations of Hepatitis C Virus Infection by Huaibin M. Ko, Juan C. Hernandez-Prera, Hongfa Zhu, Steven H. Dikman, Harleen K. Sidhu, Stephen C. Ward, Swan N. Thung

“…Other HCV-associated entities include porphyria cutanea tarda, lichen planus, necrolytic acral erythema, membranous glomerulonephritis, diabetic nephropathy, B-cell non-Hodgkin lymphomas, insulin resistance, sialadenitis, sicca syndrome, and autoimmune thyroiditis. …”
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Comparative analysis of improved m6A sequencing based on antibody optimization for low-input samples by Jiafeng Lu, Wenjuan Xia, Jincheng Li, Liya Zhang, Chunfeng Qian, Hong Li, Boxian Huang

“…Our findings demonstrated that 5 µg of Millipore antibodies (ABE572 and MABE1006) performed well, starting from 15 µg total RNA from the liver, while 1.25 µg of Cell Signaling Technology antibodies (CST) (#56593) was suitable for low-input total RNA. …”
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