miR-301a-mediated crosstalk between the Hedgehog and HIPPO/YAP signaling pathways promotes pancreatic cancer by Bing Qi, Yuqiong Wang, Xian Zhu, Yanfang Gong, Jing Jin, Hongyu Wu, Xiaohua Man, Feng Liu, Wenzhu Yao, Jun Gao

“…Functional assays demonstrated the impact of miR-301a on cell proliferation and apoptosis, particularly in synergy with TNF-α. …”
Get full text

Delirious Mania Associated with Autoimmune Gastrothyroidal Syndrome of a Mid-Life Female: The Role of Hashimoto Encephalopathy and a 3-Year Follow-Up including Serum Autoantibody L... by Udo Bonnet, Claudia Selle, Ralf Kuhlmann

“…Diagnostic analyses found no evidence of limbic encephalopathies characterized by serum antibodies against intracellular, synaptic, or further cell surface antigenic targets, neoplasm, and connective tissue or vasculitis diseases. …”
Get full text

A Framework of the Meshless Method for Topology Optimization Using the Smooth-Edged Material Distribution for Optimizing Topology Method by Jingbo Huang, Kai Long, Yutang Chen, Rongrong Geng, Ayesha Saeed, Hui Zhang, Tao Tao

“…In meshless analysis, the non-overlap cell variables instead of nodal or Gaussian-based variables are adopted to characterize the existence or absence of sub-regions. …”
Get full text

Enhancement of Methane Detection in Tunable Diode Laser Absorption Spectroscopy Using Savitzky–Golay Filtering by Shichao Chen, Xing Tian, Tong Mu, Jun Yuan, Xile Cao, Gang Cheng

“…In order to enhance gas absorption efficiency and improve the detection sensitivity of methane, a gas absorption cell with an effective optical path length of 29.37 m was developed, employing tunable diode laser absorption spectroscopy (TDLAS) and a distributed feedback (DFB) laser with a center wavelength of 1.654 μm as the light source. …”
Get full text

Evaluation of stability and in vitro wound healing potential of melatonin loaded (lipid enriched) chitosan based microspheres by Romić Marieta Duvnjak, Sušac Anja, Lovrić Jasmina, Cetina-Čižmek Biserka, Filipović-Grčić Jelena, Hafner Anita

“…Dressings wound healing potential was assessed by in vitro scratch test using human skin fibroblast cell line. Although both systems showed good stability characteristics, the addition of lipids in the system has improved its wound healing potential.…”
Get full text

Additively manufactured 316L stainless steel as a potential alternative implant material by M.S. Alam, S.R. Campbell, S.R. Spivey, G. Dutta, N. Pal, A. Karan, J. Xie, M.A. DeCoster, E.P. Murray

“…The surface characteristics of SLM 316L SS samples fabricated at 800 mm/s also promoted substantial biocompatibility that was observed via cell attachment and differentiation of osteoblasts, as well as high collagen 1A coverage indicating strong potential as a alternative implant material.…”
Get full text

Ecological System Influences in the Treatment of Pediatric Chronic Pain by Deirdre E Logan, Lisa Engle, Amanda B Feinstein, Christine B Sieberg, Penny Sparling, Lindsey L Cohen, Caitlin Conroy, Dana Driesman, Akihiko Masuda

“…Finally, an acceptance and commitment therapy-focused group intervention for children with sickle cell disease and their parents demonstrates the benefits of peer contact as an element of the therapeutic intervention.…”
Get full text

Fundamentals and Advances in Stimuli-Responsive Hydrogels and Their Applications: A Review by Iryna S. Protsak, Yevhenii M. Morozov

“…Additionally, we highlight emerging and unconventional applications such as local micro-thermometers and cell mechanotransduction. This review concludes with a discussion of current challenges and future prospects in the field, aiming to inspire further innovations and advancements in stimuli-responsive hydrogel research and applications to bring them closer to the societal needs.…”
Get full text

Cytomegalovirus in the Neonate: Immune Correlates of Infection and Protection by Mark R. Schleiss

“…Vaccine design is currently focused on strategies that aim to elicit neutralizing antibody and T-cell responses, toward the goal of preventing primary or recurrent infection in women of child-bearing age. …”
Get full text

Neglected Case of Human Balantidiasis: Presumed as Antibiotic-Associated Diarrhoea by Sreska Shrestha, Priyatam Khadka

“…The health post clinician made a presumptive diagnosis as the side effects of the antibiotics; however, the symptoms were not resolved. Complete blood cell count (CBC) was normal; renal function test (RFT) and liver function (LFT) were within the normal ranges. …”
Get full text

Dynamic Roles of RNA and RNA Epigenetics in HTLV-1 Biology by Emily M. King, Amanda R. Panfil

“…Viruses, particularly retroviruses like human T-cell leukemia virus type 1 (HTLV-1), rely heavily on RNA and RNA post-transcriptional modifications to regulate the viral lifecycle, pathogenesis, and evasion of host immune responses. …”
Get full text

Underappreciated layers of antibody-mediated immune synapse architecture and dynamics by Benjamin S. Goldberg, Margaret E. Ackerman

“…In this review, we will use insights from recent models of classical complement complexes and T cell immune synapse formation to explore how structural differences in antibody-mediated immune synapses may relate to their functional diversity.…”
Get full text

Fluorescence, Decay Time, and Structural Change of Laser Dye Cresyl Violet in Solution due to Microwave Irradiation at GSM 900/1800 Mobile Phone Frequencies by Fuat Bayrakceken, Korkut Yegin

“…These changes are important because laser-dye cresyl violet strongly bonds to DNA- and RNA-rich cell compounds in nerve tissues. The irradiation effects on the electronic structure of cresyl violet and its fluorescence data were all obtained experimentally at room temperature. …”
Get full text

Oscillatory autophagy induction is enabled by an updated AMPK-ULK1 regulatory wiring. by Orsolya Kapuy, Marianna Holczer, Luca Csabai, Tamás Korcsmáros

“…Although oscillatory behaviour is typically associated with processes like the cell cycle or circadian rhythm, emerging experimental and theoretical evidence suggests that such periodic dynamics may explain conflicting experimental results in autophagy research. …”
Get full text

3D-QSAR and Docking Studies of a Series of β-Carboline Derivatives as Antitumor Agents of PLK1 by Jahan B. Ghasemi, Valentin Davoudian

“…An alignment-free, three dimensional quantitative structure-activity relationship (3D-QSAR) analysis has been performed on a series of β-carboline derivatives as potent antitumor agents toward HepG2 human tumor cell lines. A highly descriptive and predictive 3D-QSAR model was obtained through the calculation of alignment-independent descriptors (GRIND descriptors) using ALMOND software. …”
Get full text

La traduction, entre transgression et limite by Salah Basalamah

“…En effet, la traductologie étant la discipline qui s’est intéressée dans les trente dernières années à l’étude des phénomènes du traduire en contexte (tournants culturel et sociologique), il reste pour celle-ci de développer une pensée qui réfléchit désormais le concept même de traduction. …”
Get full text

Evaluation of the survivability of CFRP honeycomb-cored panels in compression after impact tests by Oleg A. Staroverov, Elena M. Strungar, Valery E. Wildemann

“…This paper is oriented to the experimental research of the mechanics of the CFRP sandwich plates, glass and carbon fiber sample panels with a large-cell honeycomb core. The method for testing polymer composite sample plates in compression after impact (CAI) tests with joint use of a testing machine and a video system for deformation field registration was tested. …”
Get full text

Neuropathology and Neurochemistry of Nonmotor Symptoms in Parkinson's Disease by Isidro Ferrer

“…These alterations appear at early stages of the disease and may precede by years the appearance of cell loss and cortical atrophy.…”
Get full text

Genome sequence of Streptomyces antioxidans MUSC 164T isolated from mangrove forest by Hooi-Leng Ser, Nurul-Syakima Ab Mutalib, Wai-Fong Yin, Bey-Hing Goh, Learn-Han Lee, Kok-Gan Chan

“…After 31 rounds of in vitro screening using human neuronal cell line (i.e. SH-SY5Y), the extract of 32 MUSC 164T was found to possess significant neuroprotective effect against hydrogen 33 peroxide[13]. …”
Get full text