Nivolumab and Ipilimumab Combination Immunotherapy for Patients with Metastatic Collecting Duct Carcinoma by Tetsuya Danno, Shohei Iwata, Fusako Niimi, Sachi Honda, Haruka Okada, Takeshi Azuma

“…Recently, immune checkpoint inhibitors (ICI), anti-programmed death-1 (PD-1) antibody, and anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) antibody were approved for use against metastatic renal cell carcinoma. We herein described two cases of metastatic renal collecting duct carcinoma treated with a combination immunotherapy consisting of nivolumab and ipilimumab. …”
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Potential inhibition of CXCL12/SDF-1 by small molecule Hesperetin in management of tobacco associated oral cancer by G. Radha, Ramya Ramadoss, Pradeep Kumar Yadalam, Rajeshkumar Shanmugam

“…Goal of the perspective: Stromal cell-derived factor-1 alpha CXCL12/SDF-1 has a substantial impact on the tumorigenicity in tobacco related oral cancer. …”
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Gal-3 activates Tyro3 to ameliorate ferroptosis of hippocampal neurons after traumatic brain injury by Xiao Zhang, Manrui Li, Yang Xu, Jingting Wu, Ruixuan Yuan, Yihan Sun, Xiaogang Chen, Meili Lv, Bo Jin, Xiameng Chen, Weibo Liang

“…Our bioinformatics analysis of single-cell RNA sequencing data from hippocampal tissue following TBI revealed persistent neuronal loss and activation of ferroptosis-related pathways. …”
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Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery by Cynthia Koziol-White, Eric Gebski, Gaoyaun Cao, Reynold A. Panettieri

“…This innovative methodology presents a unique opportunity to bridge the gap between traditional in vitro cell cultures and in vivo animal models, offering researchers a more accurate representation of the intricate microenvironment of the lung. …”
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Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy by Marketa Vasku, Thomas Papathemelis, Nicolai Maass, Ivo Meinhold-Heerlein, Dirk Bauerschlag

“…Paraneoplastic polyneuropathy (PNP) is mostly related to small cell lung cancer (5%), prostate, gastric, and breast cancer. …”
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DiffMAP-GP: Continuous 2D diffusion maps from particle trajectories without data binning using Gaussian processes by Vishesh Kumar, J. Shepard Bryan, IV, Alex Rojewski, Carlo Manzo, Steve Pressé

“…We analyze both synthetic data, where ground truth is known, as well as data drawn from live-cell single-molecule imaging of membrane proteins. …”
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Interactions between Myc and Mediators of Inflammation in Chronic Liver Diseases by Ting Liu, Yu Zhou, Kwang Suk Ko, Heping Yang

“…These mediators are the driving force of many inflammatory liver disorders, which often result in fibrosis, cirrhosis, and liver tumorigenesis. c-Myc is involved in many cellular events such as cell growth, proliferation, and differentiation. c-Myc upregulates IL-8, IL-10, TNF-α, and TGF-β, while IL-1, IL-2, IL-4, TNF-α, and TGF-β promote c-Myc expression. …”
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CNTNAP3 Associated ATG16L1 Expression and Crohn’s Disease by Yu Qi Qiao, Mei Lan Huang, Qing Zheng, Tian Rong Wang, An Tao Xu, Yuan Cao, Di Zhao, Zhi Hua Ran, Jun Shen

“…Autophagy is a common physiological process in cell homeostasis and regulation. Autophagy-related gene mutations and autophagy disorders are important in Crohn’s disease (CD). …”
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Exploring the electronic and magnetic properties of half-heusler alloy CoMnSb: implications for spintronics by Binay Limbu, Prem Sagar Dahal

“…The total spin magnetic moments have been computed 3µB per unit cell which is in good agreement with the slater pauling rule Mt = Zt − 18 for Half Heusler alloy. …”
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Five steps in leukocyte extravasation in the microcirculation by chemoattractants by T. Oda, M. Katori, K. Hatanaka, S. Yamashina

“…After PMNs had passed through the endothelial cell layer, they remained in the venular wall for more than 30 min after application of the chemoattractants and appeared in the extravascular space. …”
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Synthesis of some benzimidazole derivatives endowed with 1,2,3-triazole as potential inhibitors of hepatitis C virus by Youssif Bahaa G. M., Mohamed Yaseen A. M., Salim Mohammed T. A., Inagaki Fuyuhiko, Mukai Chisato, Abdu-Allah Hajjaj H. M.

“…Their cytotoxicity was determined by the reduction in the number of viable cell. All of the synthesized compounds are inactive against HBV and some showed activity against HCV. …”
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Parallel median consensus clustering in complex networks by Md Taufique Hussain, Mahantesh Halappanavar, Samrat Chatterjee, Filippo Radicchi, Santo Fortunato, Ariful Azad

“…Our parallel algorithm achieves 35x speedup when utilizing 64 processing cores for large real-world graphs representing mass cytometry data from single-cell experiments.…”
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Experimental investigation of the mechanical properties of Alfas stone by Konstas N. Kaklis, Stelios P. Mavrigiannakis, Zach G. Agioutantis, Emmanouil K. Steiakakis, Foteini K. Stathogianni

“…All specimens were prepared by following the ISRM suggested methods and the load was applied using a stiff 1600 kN MTS hydraulic testing machine and a 500 kN load cell. Strain was measured using biaxial 0/90 stacked rosettes appropriately attached on each specimen.…”
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Clinical, Biochemical, and ATR-FTIR Spectroscopic Parameters Associated with Death or Survival in Patients with Severe COVID-19 by Adriana Martinez-Cuazitl, Monica M. Mata-Miranda, Miguel Sanchez-Brito, Daniel Valencia-Trujillo, Amanda M. Avila-Trejo, Raul J. Delgado-Macuil, Consuelo Atriano-Colorado, Francisco Garibay-Gonzalez, Virginia Sanchez-Monroy, Gustavo J. Vazquez-Zapien

“…Herein, we demonstrate that ATR-FTIR spectroscopy allows the description of the events related to cell damage, such as lipids biogenesis and the secondary structure of proteins associated with lactate dehydrogenase and albumin levels. …”
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Capacitance and Conductance Compensation Methods for Efficient Computing‐In‐Memory Designs by Yubiao Luo, Fei Qiao, Zhong Sun

“…It enables efficient CIM designs by intentionally letting the sum of capacitances or conductances of two or more rows or columns in the memory array equal, thus resulting in a concise mathematical formula regarding the memory cell data and the input data, which constitute computing primitives. …”
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An Elderly Lady with Fever of Unknown Etiology and Severe Pulmonary Hypertension: Intravascular Lymphoma—An Elusive Diagnosis by Nupur Sinha, Luis Lantigua, Masooma Niazi, Gilda Diaz-Fuentes

“…Intravascular lymphoma is a rare type of diffuse large B cell lymphoma, characterized by selective intravascular growth of malignant lymphocytes, aggressive behavior, and often a fatal course. …”
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Multiphoton Laser Microscopy and Fluorescence Lifetime Imaging for the Evaluation of the Skin by Stefania Seidenari, Federica Arginelli, Sara Bassoli, Jennifer Cautela, Paul M. W. French, Mario Guanti, Davide Guardoli, Karsten König, Clifford Talbot, Chris Dunsby

“…This innovative technique can be applied to the study of living skin, cell cultures and ex vivo samples. Although still limited to the clinical research field, the development of multiphoton laser microscopy is thought to become suitable for a practical application in the next few years: in this paper, we performed an accurate review of the studies published so far, considering the possible fields of application of this imaging method and providing high quality images acquired in the Department of Dermatology of the University of Modena.…”
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Primary Pericardial Mesothelioma: A Rare Entity by Mohit Godar, Jianhua Liu, Pengguo Zhang, Yang Xia, Qinghai Yuan

“…Primary pericardial malignant mesothelioma is an extremely rare neoplasm that arises from the pericardial mesothelial cell layers. Clinical symptoms and signs are frequently nonspecific, and the diagnosis is usually made after surgery or at autopsy. …”
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Probability of Exceeding Damage States in Plates Using BEM by Ernesto Pineda-León, José Manuel Rosales-Juárez, Dante Tolentino, Orlando Susarrey-Huerta

“…The domain integrals are evaluated using a cell discretization technique. A total incremental method is applied to solve the nonlinear boundary integral equations. …”
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Analytical Modelling of High Concentrator Photovoltaic Modules Based on Atmospheric Parameters by Eduardo F. Fernández, F. Almonacid, T. K. Mallick, P. Pérez-Higueras

“…The maximum power of a HCPV module is estimated as a function of direct normal irradiance, cell temperature, and two spectral corrections based on air mass and aerosol optical depth. …”
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