A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis by Rolf Müller, Martin Kömhoff, Jeffrey M. Peters, Sabine Müller-Brüsselbach

“…Recent evidence suggests that stromal PPARβ/δ regulates tumor endothelial cell proliferation and promotes differentiation leading to the properly orchestrated events required for tumor blood vessel formation. …”
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Long non-coding RNA linc00152 acting as a promising oncogene in cancer progression by Danbi Seo, Dain Kim, Wanyeon Kim

“…Recently, linc00152 (an lncRNA) was identified as a potent oncogene in various cancer types, and shown to be involved in cancer cell proliferation, invasiveness, and motility by sponging tumor-suppressive microRNAs acting as a competing endogenous RNA, binding to gene promoters acting as a transcriptional regulator, and binding to functional proteins. …”
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Mitochondrial Dysfunction in Parkinson's Disease by P. C. Keane, M. Kurzawa, P. G. Blain, C. M. Morris

“…This paper aims to illustrate the considerable body of evidence linking mitochondrial dysfunction with neuronal cell death in the substantia nigra pars compacta (SNpc) of PD patients and to highlight the important need for further research in this area.…”
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Necrotizing Liver Granuloma/Abscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granul... by Sanem Eren Akarcan, Neslihan Karaca, Guzide Aksu, Halil Bozkaya, Mehmet Fatih Ayik, Yasemin Ozdemir Sahan, Mehmet Arda Kilinc, Zafer Dokumcu, Cenk Eraslan, Emre Divarci, Hudaver Alper, Necil Kutukculer

“…The devastating course of disease regardless of the mutation emphasizes the importance of early diagnosis and intervention of hematopoietic stem cell transplantation as soon as possible in children with CGD.…”
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Inverse design of high-NA metalens for maskless lithography by Chung Haejun, Zhang Feng, Li Hao, Miller Owen D., Smith Henry I.

“…First, we derive a computational upper bound for a unit-cell-based axisymmetric metalens. Then, we demonstrate a fabrication-compatible inverse-designed metalens with 85.50% transmission normalized focusing efficiency at 0.6 numerical aperture at 405 nm wavelength; a higher efficiency than a theoretical gradient index lens design (79.98%). …”
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Overview of the evaluation of the destructive effect of procarbazine on the ovarian reserve in the apoptotic, inflammatory, and oxidative pathways by Kezban Kartlasmis, Ayse Nur Cakir Gungor, Yurdun Kuyucu, Samet Kara

“…Procarbazine has a detrimental impact on ovarian reserve by directly targeting the oocyte or indirectly through somatic cell destruction. Evidence gathered thus far indicates that procarbazine’s mode of action in the ovaries may involve apoptosis, inflammation, and oxidative stress. …”
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Hybrid Natural and Forced Active Balancing Control of Battery Packs State of Charge Based on Partnership for a New Generation of Vehicles by Yewen Wei, Shuailong Dai, Jiayu Wang, Zhifei Shan, Jie Min

“…Battery packs are widely used in electric vehicles, and their state-of-charge is one of the essential issues that affect the performances, whilst the balance between parallel and series cell of the battery pack always has an obvious effect. …”
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Synaptic Remodeling in the Dentate Gyrus, CA3, CA1, Subiculum, and Entorhinal Cortex of Mice: Effects of Deprived Rearing and Voluntary Running by Andrea T. U. Schaefers, Keren Grafen, Gertraud Teuchert-Noodt, York Winter

“…Hippocampal cell proliferation is strongly increased and synaptic turnover decreased after rearing under social and physical deprivation in gerbils (Meriones unguiculatus). …”
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Two-plasmon-decay instability stimulated by dual laser beams in inertial confinement fusion by C.-W. Lian, Y. Ji, R. Yan, J. Li, L.-F. Wang, Y.-K. Ding, J. Zheng

“…In this paper, TPD collectively driven by dual laser beams consisting of a normal-incidence laser beam (Beam-N) and a large-angle-incidence laser beam (Beam-L) is investigated via particle-in-cell simulations. It is found that significant TPD growth can develop in this regime at previously unexpected low laser intensities if the intensity of Beam-L exceeds the large-angle-incidence threshold. …”
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A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma by Masanori Sakakima, Yoshihide Fujigaki, Hideo Yasuda, Akashi Togawa, Tomoyuki Fujikura, Atsushi Otsuka, Seiichiro Ozono, Akira Hishida

“…Renal tissue revealed no apparent glomerulopathy with tubular atrophy, interstitial fibrosis, and mildly-to-moderately interstitial mononuclear cell infiltration. Immunofluorescence study showed no deposition of immunoreactanct, and electron microscopy showed almost normal glomerulus without electron dense deposit. …”
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Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020 by Yanqing Liu, Jie Chen, Xiang Li, Yu Fan, Cheng Peng, Xiaochun Ye, Yingshuang Wang, Xin Xie

“…RAS proteins, as pivotal signal transduction molecules, are frequently mutated and hyperactivated in various human cancers, closely associated with tumor cell proliferation, survival, and metastasis. Despite extensive research on RAS targeted therapies, developing effective RAS inhibitors remains a significant challenge. …”
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Seroprevalence and pathological investigation of salmonellosis in poultry by M. Al Mamun, M. Jamal Uddin Bhuiyan, M. Ali Zinnah, Abul Khair, M. Mahmudul Hassan, M. Bashir Uddin

“…Various macroscopically and microscopically pathologic lesions observed especially in the liver (haemorrhage, necrotic foci, heterophil infiltration) and intestine (goblet cell proliferation).<p> <b>Conclusion:</b> Further studies are need for the determination of the presence of Salmonella infection in farms of Bangladesh.…”
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An Analytic Contemplation of the Conspicuous Vicissitudes in the Histomorphology of Corpuscles of Stannius of a Freshwater Catfish Mystus tengara (Hamilton, 1822) due to the Exposu... by Nilanjana Chatterjee, Baibaswata Bhattacharjee

“…The population of the cell type with granular cytoplasm showed significant increase at the expense of the other that consisted of agranular cytoplasm with increasing nanoparticle concentration. …”
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Analysis of Geometries' Effects on Rotating Stall in Vaneless Diffuser with Wavelet Neural Networks by Chuang Gao, Chuangang Gu, Tong Wang, Bo Yang

“…With the trained WNN, detailed investigation was carried out mainly to understand the effects of impeller blade number, blade-exit angle, impeller rotating speed, diffuser radius ratio, and width ratio on stall inception and cell speed of vaneless diffuser. Network results clearly show the existence of distinct stall mechanisms for narrow and wide diffusers, which also make different responses to variation of the above- mentioned parameters.…”
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A Pleural Solitary Fibrous Tumor, Multiple Gastrointestinal Stromal Tumors, Moyamoya Disease, and Hyperparathyroidism in a Patient Associated with NF1 by Yoko Yamamoto, Ken Kodama, Shigekazu Yokoyama, Masashi Takeda, Shintaro Michishita

“…Loss of the gene function, due to a point mutation, leads to an increase in cell proliferation and the development of several tumors. …”
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Two Rare Complications in One Patient: Acquired von Willebrand Syndrome Associated with Intracranial Plasmacytoma by H. Auge, C. Yguel, E. Schmitt, B. Frotscher, H. Busby-Venner, R. Morizot, C. Moulin, P. Feugier, A. Perrot, L. Filliatre-Clement

“…The patient received induction therapy with bortezomib, thalidomide, and dexamethasone (VTD), followed by high-dose melphalan chemotherapy and autologous stem cell transplantation, and then VTD consolidation, and finally maintenance with lenalidomide. …”
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Dengue infection changes the expressions of CD154 and CD148 in human platelets by Sayali Vedpathak, Sonali Palkar, AkhileshChandra Mishra, Vidya A Arankalle, Shubham Shrivastava

“…Upon pathogen recognition, platelets rapidly modulate the expression of adhesion molecules to trigger immune cell interactions and regulate the immune response. …”
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Subtle‐but‐smouldering myocardial injury after immune checkpoint inhibitor treatment accompanied by amyloid deposits by Mizuki Ida, Shiro Nakamori, Shinya Yamamoto, Seimi Watanabe, Kyoko Imanaka‐Yoshida, Masaki Ishida, Hajime Sakuma, Keiichi Yamanaka, Kaoru Dohi

“…Abstract Although cardiac troponin is a highly specific biomarker for myocardial cell injury, it is important to recognize the pitfalls of this test in the diagnosis and management of immune checkpoint inhibitor (ICI) myocarditis. …”
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Systemic Treatments for Noninfectious Vitreous Inflammation by Angela Jiang, Jillian Wang, Malav Joshi, John Byron Christoforidis

“…These categories include corticosteroids, antimetabolites, alkylating agents, T-cell inhibitors/calcineurin inhibitors, and biologic agents. …”
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Fructan Biosynthetic and Breakdown Enzymes in Dicots Evolved From Different Invertases. Expression of Fructan Genes Throughout Chicory Development by Wim Van den Ende, An Michiels, Joke De Roover, Andrea Van Laere

“…Unlike fructan biosynthetic genes that originated from vacuolar-type invertase, fructan exohydrolases (FEHs) seem to have evolved from a cell-wall invertase ancestor gene that later obtained a low iso-electric point and a vacuolar targeting signal. …”
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