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25081
E3 ubiquitination ligase XIAP lightens diabetes‐induced cognitive impairment by inactivating TXNIP‐ERS‐mediated neuronal injury
Published 2025-01-01“…This study aims to elucidate the role and mechanisms of the X‐linked inhibitor of apoptosis protein (XIAP)/thioredoxin‐interacting protein (TXNIP) in hippocampal neuron cell death and cognitive function within DCD models. …”
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25082
Salvation of a solitary kidney in a patient with grade IV renal trauma: a case report
Published 2022-08-01“…Acquired causes include nephrectomy performed for reasons including traumatic kidney injury, disease (e.g., renal cell carcinoma), and donation for kidney transplantation. …”
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25083
An Acute Jejunojejunal Intussusception Revealing a Metastatic Combined Lung Cancer
Published 2021-01-01“…He underwent an en bloc resection, and pathological findings concluded to a metastasis of a pulmonary combined small cell carcinoma and adenocarcinoma. A subsequent CT scan revealed the primitive mass of the right lung with no evidence of secondary localization. …”
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25084
Revolutionizing ovarian cancer therapy by drug repositioning for accelerated and cost-effective treatments
Published 2025-01-01“…This review focuses on drug repositioning for ovarian cancer treatment, showcasing a comprehensive exploration grounded in thorough in vitro experiments across diverse cancer cell lines, which are validated through preclinical in vivo models. …”
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25085
Harmful Effects of Hyperoxia in Postcardiac Arrest, Sepsis, Traumatic Brain Injury, or Stroke: The Importance of Individualized Oxygen Therapy in Critically Ill Patients
Published 2017-01-01“…Providing supplementary oxygen can increase oxygen delivery in hypoxaemic patients, thus supporting cell function and metabolism and limiting organ dysfunction, but, in patients who are not hypoxaemic, supplemental oxygen will increase oxygen concentrations into nonphysiological hyperoxaemic ranges and may be associated with harmful effects. …”
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25086
Hypoxic-Ischemic Injury in the Developing Brain: The Role of Reactive Oxygen Species Originating in Mitochondria
Published 2012-01-01“…Mitochondrial dysfunction is the most fundamental mechanism of cell damage in cerebral hypoxia-ischemia and reperfusion. …”
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25087
Stauffer’s Syndrome in Patient with Metastatic Prostate Cancer
Published 2019-01-01“…Classically Stauffer syndrome has been described in renal cell cancer patients. In literature cholestasis as manifestation of paraneoplastic syndrome has also been described in patients with prostate adenocarcinoma and pancreatic and bronchogenic carcinoma. …”
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25088
Cardiac Calcified Amorphous Tumor in the Neonatal Period
Published 2022-01-01“…A histopathological study demonstrated the presence of thrombus-like tissue with extensive calcification and foreign body type giant cell reactions. After operation, the patient had an uneventful hospitalization. …”
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25089
Carcinosarcoma of the Thyroid Gland
Published 2015-01-01“…End diagnosis was a papillary carcinoma of the thyroid with spindle cell component. Thus the nodule was recognized to be a carcinosarcoma. …”
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25090
PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival
Published 2024-11-01“…The 3 missense mutations that were identified each carry severe phenotypic consequences that correlate with the presence or not of residual PDE12 protein, show cell-type-specific adaptive responses, and specificity in the mtDNA-encoded electron transport chain subunits that are most affected. …”
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25091
A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of Roadmap Genomics ChromHMM Annotations: A Computational Perspective
Published 2018-12-01“…Our aim was to identify the relationship between DNA sequence units and their chromatin variability based on integrated ChromHMM datasets of different cell and tissue types.…”
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25092
Performance Analysis on MU-MIMO Field Test in TD-LTE System
Published 2013-05-01“…Due to the multiplexing of time-frequency resource,the valid transmission resource can be increased remarkably,thus the gain on dua1-terminal throughput and the cell overall throughput performance can be obtained. …”
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25093
The biological and functional restoration of spinal cord injury
Published 2024-12-01“…Restoration of the anatomical structure and microenvironment of the damaged region can be obtained by molecular drug modulation, neuroprotection, neuroregeneration, stem cell therapy, and biomaterial‐based tissue engineering. …”
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25094
Purification of Anti-Interleukin-6 Monoclonal Antibody Using Precipitation and Immobilized Metal-Ion Affinity Chromatography
Published 2015-02-01“…The objective of this study was to recover and purify an anti-interleukin-6 MAb from cell culture supernatant by a combined method involving precipitation and immobilized metal-ion affinity chromatography (IMAC), aiming its subsequent application in diagnostic kits. …”
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25095
Laser Capture Microdissection in Dentistry
Published 2010-01-01“…Laser capture microdissection (LCM) allows for the microscopic procurement of specific cell types from tissue sections that can then be used for gene expression analysis. …”
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25096
Hepatocyte growth factor stimulates neutrophil degranulation but not respiratory burst
Published 1993-01-01“…Neutrophil function is regulated in part by cytokines with growth factor activities for different cell types. Hepatocyte growth factor (HGF) is a cytokine produced during injury to the liver and other organs. …”
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25097
Susceptibility of lung epithelium to neutrophil elastase: protection by native inhibitors
Published 1997-01-01“…We investigated the effect of NE on respiratory epithelial cell adherence in vitro , in the presence of varying concentrations and combinations of native inhibitors, α-1-proteinase inhibitor (PI) and secretory leukoprotease inhibitor (SLPI). …”
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25098
PROTAC-based therapeutics for targeting HPV oncoproteins in head and neck cancers
Published 2025-12-01“…The increasing incidence of Human Papillomavirus (HPV)-related head and neck cancers, particularly oropharyngeal squamous cell carcinomas, highlights the need for advanced therapeutic options beyond the traditional modalities of surgery, radiation, and chemotherapy, which often lead to significant morbidity and lack specificity in targeting the molecular pathogenesis of the disease. …”
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25099
A Rare Case of Superior Mesenteric Artery Thrombosis in Multiple Myeloma
Published 2024-12-01“…This case report emphasizes the importance to rule out the possibility of plasma cell dyscrasias in elderly patients presenting with clinical features of mesenteric artery thrombosis.…”
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25100
Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature
Published 2013-01-01“…Burkitt's lymphoma (BL) is an aggressive B-cell malignancy with very high proliferation rate, more common in males than females. …”
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