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24961
Metagenomic analysis of DNA viruses from posttransplant lymphoproliferative disorders
Published 2019-03-01“…In multivariable analyses, T cell PTLD (P = 0.006) and TTV PCR level (P = 0.012) remained significant. …”
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24962
20(S)-Ginsenoside Rg3 Protects Kidney from Diabetic Kidney Disease via Renal Inflammation Depression in Diabetic Rats
Published 2020-01-01“…Through periodic acid-Schiff staining, we observed that the change in renal histology was improved and renal tubular epithelial cell apoptosis decreased significantly by treatment with 20(S)-Rg3. …”
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24963
Comprehensive analysis of a-and b-thalassemia genotypes and hematologic phenotypes
Published 2025-01-01“…Methods: A total of 1174 patients with thalassemia were collected in Guizhou Provincial People's Hospital from October 2020 to December 2021 by PCR-reverse dot blot (RDB) hybridization assay, and their red blood cell (RBC), hemoglobin (Hb), mean erythrocyte volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), hemoglobin (HbA), hemoglobin A2 (HbA2), and fetal hemoglobin (HbF) data were collected. …”
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24964
Synthesis of bioactive quinazolin-4(3H)-one derivatives via microwave activation tailored by phase-transfer catalysis
Published 2020-06-01“…Some of the synthesized compounds were screened for their antitumor activity against different human tumor cell lines. The screened compounds exhibited a significant antitumor activity on some of the cancer cell lines, melanoma (SK-MEL-2), ovarian cancer (IGROV1), renal cancer (TK-10), prostate cancer (PC-3), breast cancer (MCF7) and colon cancer (HT29). …”
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24965
Machine learning-driven identification of critical gene programs and key transcription factors in migraine
Published 2025-01-01“…Methods We utilized single-nucleus RNA sequencing (snRNA-seq) data from 43 brain regions, along with genome-wide association study (GWAS) data, to investigate susceptibility to migraine. The cell-type-specific expression (CELLEX) algorithm was employed to calculate specific expression profiles for each region, while non-negative matrix factorization (NMF) was applied to decompose gene programs within the single-cell data from these regions. …”
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24966
Concurrent Renorrhaphy During Renal Mass Excision in Laparoscopic Nephron-Sparing Surgery: A Novel Surgical Technique
Published 2025-07-01“…The pathologic report confirmed a 2.5 × 2 × 2 cm clear cell renal cell carcinoma. No major complications were observed during surgery. …”
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24967
Thromboelastography in Patients with Inflammatory Bowel Disease
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24968
Author Correction: Classification of distinct tendinopathy subtypes for precision therapeutics
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24969
Knowledge, Attitudes, and Practices of Chronic Type 2 Diabetes Patients in China Toward Continuous Glucose Monitoring: An Online Questionnaire Survey
Published 2025-01-01“…Bingling Liu,1 Xueyi Wu,2 Xiao Zou,1 Fei Sun,1 Jie Yu1 1Department of Endocrinology, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang, 332000, People’s Republic of China; 2Department of Endocrinology, The Second People’s Hospital of Guiyang, Guiyang, 550081, People’s Republic of ChinaCorrespondence: Jie Yu, Department of Endocrinology, Jiujiang City Key Laboratory of Cell Therapy, No. 1 People’s Hospital, Jiujiang, 332000, People’s Republic of China, Tel +86-18370277823, Email 47938498@qq.comPurpose: Investigate the knowledge, attitude, and practices (KAP) of type 2 diabetes patients regarding continuous glucose monitoring (CGM).Methods: A cross-sectional study was undertaken at the First People’s Hospital of Jiujiang City from Sep 20, 2023, to Dec 10, 2023.Results: A total of 633 patients with type 2 diabetes mellitus accessed the questionnaire link. …”
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24970
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24971
Integrative analyses of mendelian randomization and bioinformatics reveal casual relationship and genetic links between COVID-19 and knee osteoarthritis
Published 2025-01-01“…Subsequent analyses, including transcriptional regulation analysis, immune cell infiltration analysis, single-cell analysis, and druggability evaluation, were performed to explore potential mechanisms and prioritize therapeutic targets. …”
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24972
Simultaneous Anti-Tuberculosis and Anti-Tumor Treatment with Immune Checkpoint Inhibitors for Co-Existent Pulmonary Tuberculosis and Advanced Lung Cancer
Published 2025-01-01“…Relevant examinations were completed after admission, and chest computed tomography revealed that the patient had lung squamous cell carcinoma with multiple metastases in lymph nodes and liver. …”
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24973
Prevalence and prognosis of malignancy in THSD7A-associated membranous nephropathy: a systematic literature review and clinical case study
Published 2024-12-01“…In our center, we followed up with 15 patients diagnosed with THSD7A-associated MN and observed three cases of concomitant tumors: two cases of lung adenocarcinoma and one case of small cell lung cancer with multiple metastases. The prevalence of malignancy in our cohort was 20%. …”
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24974
Novel Poly-Arginine Peptide R18D Reduces α-Synuclein Aggregation and Uptake of α-Synuclein Seeds in Cortical Neurons
Published 2025-01-01“…Thereafter, this study examined the therapeutic potential of the neuroprotective CARP, R18D (18-mer of D-arginine), to prevent the aforementioned PD pathogenic processes through a cell-free thioflavin-T (ThT) assay and in cortical neurons. …”
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24975
Incidence and predictors of mortality among HIV positive children on anti-retroviral therapy in the selected health facilities of West Wollega Zone, Western Ethiopia: Retrospective...
Published 2025-01-01“…Anemia, WHO clinical stage, CD4 cell count, and delayed developmental milestones were independent predictors of mortality. …”
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24976
Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis
Published 2023-01-01“…The protein FGF9 was tested by western blotting. Cell counting kit-8 (CCK8), plate cloning assay, and flow cytometry were conducted to evaluate cell proliferation and apoptosis. …”
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24977
Insights into incompatible plasmids in multidrug-resistant Raoultella superbugs
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24978
Sex reversal induced by 17β-estradiol may be achieved by regulating the neuroendocrine system of the Pacific white shrimp Penaeus vannamei
Published 2025-01-01“…The observed retardation in growth in the EM group may be attributed to the potential for neuronal damage and disruptions in the cell cycle and PI3K-Akt signaling pathways. Furthermore, the success of E2-induced sex reversal may be associated with the downregulation of neuroactive ligand-receptor interaction, dopaminergic synapse, and insulin signaling pathways, as well as the activation of steroidogenesis. …”
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24979
Efficacy of PD-1/PD-L1 Inhibitors versus Chemotherapy in Lung Cancer with Brain Metastases: A Systematic Review and Meta-Analysis
Published 2022-01-01“…Among different pathological types, the OS pooled HR was 0.67 (95%CI=0.39–0.95) for non-small cell lung cancer (NSCLC) and 0.94 (95%CI=0.56–1.33) for small cell lung cancer (SCLC); the PFS pooled HR was 0.58 (95%CI=0.39–0.76) for NSCLC and 0.79 (95%CI=0.65–0.93) for SCLC. …”
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24980
Correlation of diabetes and adverse outcomes in hospitalized COVID-19 patients admitted to a tertiary hospital in China during a small-scale COVID-19 outbreak
Published 2025-01-01“…Body mass index (BMI), C-reactive protein (CRP), pH, D-dimer, blood osmotic pressure, serum creatinine, white blood cell count, creatine kinase and hospitalization expenses were significantly different between diabetic group and non-diabetic group (p < 0.05). …”
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