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24881
Chemistry and pharmacological diversity of quinoxaline motifs as anticancer agents
Published 2019-06-01“…Tireless commitment to searching for novel therapeutic medicines is a worthwhile adventure in synthetic chemistry because of the drug resistance predicament and regular outbreak of new diseases due to abnormal cell growth and proliferation. Medicinal chemistry researchers and pharmacists have unveiled quinoxaline templates as precursors of importance and valuable intermediates in drug discovery because they have been established to possess diverse pharmacological potentials. …”
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24882
Application of Spatial Transcriptomics in Digestive System Tumors
Published 2024-12-01“…This review also discusses the importance of combining spatial transcriptomics with single-cell RNA sequencing (scRNA-seq), artificial intelligence, and machine learning in digestive system cancer research.…”
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24883
SEM/EDX and XRD characterization of silver nanocrystalline thin film prepared from organometallic solution precursor
Published 2013-01-01“…The results of XRD powder pattern examination show that Ag nanoparticles are pure phase, well crystallized. The unit cell dimensions measured on synthesized Ag nano films show small but frequent contraction in comparison to Ag metal standard.…”
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24884
Variations to the Nanotube Surface for Bone Regeneration
Published 2013-01-01“…The complex mechanisms of the bone cell-surface interactions are yet to be completely understood, and researchers continue to strive to uncover the fully optimized implant material for perfect osseointegration. …”
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24885
Anesthetic Management of a Child with Mitochondrial Neurogastrointestinal Encephalopathy
Published 2015-01-01“…She had multiple anesthetics while undergoing allogeneic hematopoietic stem cell transplantation. This case report will discuss the successful repeated use of the same anesthetic in this pediatric patient, with the avoidance of volatile anesthetic agents, propofol, and muscle relaxant.…”
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24886
Predictive Factors of Response to Biological Disease Modifying Antirheumatic Drugs: Towards Personalized Medicine
Published 2014-01-01“…Genetic background, cytokine levels, and immune cell phenotypes could also influence biological therapy response. …”
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24887
Iron metabolism in rheumatic diseases
Published 2025-06-01“…Altered iron homeostasis can contribute to disease progression through ROS production, fibrosis, inflammation, abnormal bone homeostasis, NETosis and cell senescence. In this review, we have focused on the iron metabolism in rheumatic disease and its role in disease progression.…”
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24888
Rectal Adenocarcinoma With Pagetoid Spread: A Novel Entity
Published 2024-01-01“…It is often misdiagnosed as eczema, leukoplakia, squamous cell carcinoma, Bowen’s disease, lichen planus, or condylomata acuminata. …”
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24889
Dyspnea due to Pulmonary Vessel Arteritis
Published 2014-01-01“…Only large vessel vasculitis is associated with pulmonary hypertension; primary forms include Takayasu arteritis and giant cell arteritis. The diagnosis of pulmonary arteritis can be challenging and the associated morbidity is serious without prompt, directed treatment. …”
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24890
Kinetics of Cation Desorption from Heterogeneous Solid Surface at Very Low Coverage
Published 1985-03-01“…The kinetics of this slow desorption were studied using radioactive tracers in a flow cell experiment. On a number of real adsorbents the kinetics are explained by rate limiting desorption from random, weakly heterogeneous surface sites. …”
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24891
A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis
Published 2023-07-01“…Plurihormonal pituitary adenomas produce hormones of more than one different pituitary cell lineage. Pituitary adenoma with a single hormonal content has been documented with concurrent primary granulomatous hypophysitis. …”
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24892
A Guide to Tracking Physical Activity
Published 2016-08-01“…This 3-page fact sheet explains the different free and low-cost cell phone apps, websites, and portable devices available for tracking physical activity. …”
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24893
The Complex Role of STAT3 in Viral Infections
Published 2015-01-01“…Signal transducer and activators of transcription-3 (STAT3) regulates diverse biological functions including cell growth, differentiation, and apoptosis. In addition, STAT3 plays a key role in regulating host immune and inflammatory responses and in the pathogenesis of many cancers. …”
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24894
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24895
Pathophysiological Roles of Cytokine-Chemokine Immune Network
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24896
Basic Principles of Electrospinning, Mechanisms, Nanofibre Production, and Anticancer Drug Delivery
Published 2022-01-01“…The implication of this study is the application of some of the merits of ES nanofibres (biocompatability, biodegradability, low-cost production, small pore size, and ability to transport anticancer drug to the target cell or organ) to overcome the challenges experienced in the use of anticancer chemotherapeutic agents.…”
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24897
A Guide to Tracking Physical Activity
Published 2016-08-01“…This 3-page fact sheet explains the different free and low-cost cell phone apps, websites, and portable devices available for tracking physical activity. …”
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24898
Die Auflösung der Differenz
Published 2015-07-01“…Ce cadre théorique questionne l’ancrage historique des romans, tant dans la période national-socialiste que dans celle de la République Fédérale. Dans tous les cas, ces deux romans se jouent au cœur d’une sphère liminale où humanité et animalité ne cessent d’interférer, rendant caduque toute tentative de définir l’humain en tant que tel.…”
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24899
Autour des critiques du concept de sexe. Entretien avec Anne Fausto-Sterling
Published 2014-12-01“…This text is a dialogue between Anne Fausto-Sterling, Professor Emerita of Biology and Gender Studies in the Department of Molecular and Cell Biology and Biochemistry at Brown University, and Priscille Touraille, anthropologist at the CNRS (Centre national de la recherche scientifique) in the department of eco-anthropology and ethnology of the National Museum of Natural History in Paris. …”
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24900