Model systems of human immunodef iciency virus (HIV-1) for in vitro eff icacy assessment of candidate vaccines and drugs against HIV-1 by N. B. Rudometova, D. N. Shcherbakov, A. P. Rudometov, A. A. Ilyichev, L. I. Karpenko

“…The classical method of virology, which makes it possible to evaluate the neutralizing activity of the sera of animals immunized with experimental vaccines and the eff icacy of chemotherapy agents is the method of neutralization using viral isolates and infectious molecular clones, i. e. infectious viral particles obtained via cell transfection with a plasmid vector including the full-length HIV-1 genome coding structural, regulatory, and accessory proteins of the virus required for the cultivation of replication-competent viral particles in cell culture. …”
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A systematic screening assay identifies efficient small guide RNAs for CRISPR activation by Elin Arvidsson, Diana Duarte Lobo, Diana Duarte Lobo, Ermelinda Sabarese, Fabio Duarte, Rui Jorge Nobre, Rui Jorge Nobre, Rui Jorge Nobre, Luis Quintino, Cecilia Lundberg

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Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association by Martora F, Battista T, Giordano A, Potestio L, Megna M

“…Fabrizio Martora,* Teresa Battista,* Antonella Giordano, Luca Potestio, Matteo Megna Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy*These authors contributed equally to this workCorrespondence: Fabrizio Martora, Section of Dermatology - Department of Clinical Medicine and Surgery, University of Naples Federico II, Via Pansini 5, Napoli, 80131, Italy, Tel +39 - 081 – 7462457, Fax +39 - 081 – 7462442, Email fabriziomartora92@libero.itAbstract: Hypergammaglobulinemia is a sign of B cell and plasma cell hyperactivity marked by elevated levels of gamma globulins, proteins within the gamma fraction of serum electrophoresis, linked to diseases like acute hepatitis, Hodgkin’s lymphoma, autoimmune conditions, and neoplasms. …”
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Unveiling the Electrocatalytic Performances of the Pd-MoS₂ Catalyst for Methanol-Mediated Overall Water Splitting by Aviraj M. Teli, Sagar M. Mane, Rajneesh Kumar Mishra, Wookhee Jeon, Jae Cheol Shin

“…Excitingly, the Pd-MoS₂∥Pd-MoS₂ cell reveals a small potential of 1.581 V compared to the MoS₂∥MoS₂ cell (1.648 V) in methanol-mediated overall water splitting. …”
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Programming scheduled self-assembly of circadian materials by Gregor Leech, Lauren Melcher, Michelle Chiu, Maya Nugent, Shirlaine Juliano, Lily Burton, Janet Kang, Soo Ji Kim, Sourav Roy, Leila Farhadi, Jennifer L. Ross, Moumita Das, Michael J. Rust, Rae M. Robertson-Anderson

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Gene expression analysis reveals mir-29 as a linker regulatory molecule among rheumatoid arthritis, inflammatory bowel disease, and dementia: Insights from systems biology approach... by Devi Soorya Narayana S, Vino Sundararajan

“…These hub genes were mostly enriched in significant processes and pathways like tissue development, collagen binding, cell adhesion, regulation of ERK1/2 cascade, PI3K-AKT signaling, and cell surface receptor signaling. …”
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An Innovative Drug Delivery System Loaded with a Modified Combination of Triple Antibiotics for Use in Endodontic Applications by Ardavan Parhizkar, Hanieh Nojehdehian, Fahimeh Tabatabaei, Saeed Asgary

“…PPCMs demonstrated pH close to normal physiological environment and antibacterial activity against E. faecalis and A.a in the first 2 days. MTT showed cell viability of more than 70% for PPCMs after 24 h and 72 h of exposure. …”
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La genèse et la manifestation des structures d’un point de vue cognitiviste et (post-)structuraliste by Sébastien Miravete

“…Les structuralistes sont en effet parvenus à mettre au jour des « structures », mais ils n’ont pas expliqué la formation de celles-ci ou la manière dont celles-ci se manifestent, par exemple, sous la forme de normes phonologiques ou sociales particulières. …”
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Key wound healing genes as diagnostic biomarkers and therapeutic targets in uterine corpus endometrial carcinoma: an integrated in silico and in vitro study by Fuchuan Jiang, Sajjad Ahmad, Sadia kanwal, Yasir Hameed, Qian Tang

“…These genes exhibited significantly lower expression in UCEC cell lines compared to normal controls, as confirmed by RT-qPCR. …”
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Introduction. L’actualisation de la mémoire du communisme en Europe by Lisa Tanguay, Hélène Levesque

“…Qu’il s’agisse de mémoires individuelles ou collectives, les Russes, Roumains, Polonais ou Français ont vécu des expériences dissemblables et ils participent à la création d’une mosaïque mémorielle hétéroclite.Ainsi, à l’instar de l’année 2005, ce premier numéro de Conserveries mémorielles permettra d’actualiser la discordance des mémoires devant la singularité d’une expérience commune : celle du communisme. Individuelles ou collectives, les mémoires du communisme servent à combler le vide qu’il soit identitaire ou politique. …”
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Utility of a New Artificial Dermis as a Successful Tool in Face and Scalp Reconstruction for Skin Cancer: Analysis of the Efficacy, Safety, and Aesthetic Outcomes by Fedele Lembo, Liberato Roberto Cecchino, Domenico Parisi, Aurelio Portincasa

“…The malignant tumors excised were basal cell carcinoma (68.75%), squamous cell carcinoma (18.75%), malignant melanoma (6.25%), and sarcoma (6.25%). …”
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The impact of family members on aging persons’ technology use intentions by Freek Van Baelen, Melissa De Regge, Bart Larivière, Katrien Verleye, Kristof Eeckloo

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Effects of Particulate Matter Exhaust on Functional Parameters of Organ Systems and Reactive Oxygen Species: A Cross-Sectional Study by Manjula Shivanagappa, SS Malini, Thanmayi Mahadeshwara Prasad, D. R. Mahadeshwara Prasad

“…Every organism on Earth has been exposed to minute foreign particles which enter the organ system and disrupt the cellular processes, interact with membranes, cell organelles, DNA, and other proteins to establish a series of dynamic bio-physico-chemical interactions. …”
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Characterizing the pan-cancer role of exosomal miRNAs in metastasis across cancers by Piyush Agrawal, Gulden Olgun, Arashdeep Singh, Vishaka Gopalan, Sridhar Hannenhalli

“…Here, we aimed to characterize the role of exomiRs, derived from seven cancer types (four cell lines and three tumors), in influencing the pre-metastatic niche (PMN). …”
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Synthesis, In vitro antimicrobial activity, and In silico bioinformatical approach of xanthone-fatty acid esters against Staphylococcus aureus, Escherichia coli, and Candida albica... by Yehezkiel Steven Kurniawan, Ervan Yudha, Jumina, Harno Dwi Pranowo, Eti Nurwening Sholikhah

“…The in vitro cytotoxicity assay against the NIH3T3 cell line showed that xanthyl laurate was non-toxic at 500 μg/mL with a cell viability percentage of 86.14 ± 1.38 %. …”
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Advances in Therapy for Urothelial and Non-Urothelial Subtype Histologies of Advanced Bladder Cancer: From Etiology to Current Development by Whi-An Kwon, Ho Kyung Seo, Geehyun Song, Min-Kyung Lee, Weon Seo Park

“…Among these, the 2022 World Health Organization classification of urinary tract tumors identifies a range of less common subtypes of invasive UC, formerly known as variants, which are considered high-grade tumors, including squamous cell, small-cell, sarcomatoid urothelial, micropapillary, plasmacytoid, and urachal carcinomas, and adenocarcinoma. …”
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Relationship between PLR and Clinicopathological Characteristics of Patients with Advanced NSCLC and Its Predictive Value for the Efficacy of Chemotherapy and Prognosis by Jianming Zhao, Yiping Pan, Yu Sheng, Jun Sun

“…To investigate the relationship between blood platelet-to-lymphocyte ratio (PLR) and clinicopathological characteristics of patients with advanced non-small cell lung cancer (NSCLC) and evaluate the value of PLR for predicting the efficacy of chemotherapy and prognosis. …”
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The Effectiveness of Varying Combination Ratios of A. cordifolia and M. indica against Field and Laboratory Strains of P. falciparum In Vitro by Yakubu Jibira, Elizabeth Cudjoe, Frederick M. Tei-Maya, Benjamin Ayensu, Linda E. Amoah

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Is Whole‐Brain Radiotherapy for Brain Metastases an Overestimated Therapy? A Retrospective Study of Real‐World Data Using Landmark Analyses by Florian Hoelzl, Oliver Koelbl, Isabella Gruber

“…Results The median patient age was 62 years. Non‐small cell lung cancer (n = 95), breast cancer (n = 53), and small cell lung cancer (n = 48) were the most frequent cancer types. …”
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Nurses' Experiences With Mentoring Nursing Students in Nursing Homes Where an Active, Collaborative Learning Model Is Introduced. A Qualitative Study by Anne Raustøl, Kirsten Eika Amsrud, Eli‐Anne Skaug, Anne Lyberg, Bodil Tveit

“…In our study, a model where one mentor supports a learning cell of two students, again being supported by a team of two persons in joint positions, was explored. …”
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