A stretchable human lung‐on‐chip model of alveolar inflammation for evaluating anti‐inflammatory drug response by Clémentine Richter, Lorenz Latta, Daria Harig, Patrick Carius, Janick D. Stucki, Nina Hobi, Andreas Hugi, Paul Schumacher, Tobias Krebs, Alexander Gamrekeli, Felix Stöckle, Klaus Urbschat, Galia Montalvo, Franziska Lautenschläger, Brigitta Loretz, Alberto Hidalgo, Nicole Schneider‐Daum, Claus‐Michael Lehr

“…The model is based on the human alveolar epithelial cell line Arlo co‐cultured with macrophages differentiated from the THP‐1 cell line, creating a physiological biological microenvironment. …”
Get full text

Analysis of clinical characteristics of hemorrhagic fever with renal syndrome with acute pancreatitis: a retrospective study by Lihua Huang, Min Xiao, Xiaoling Huang, Jun Wu, Jiao Luo, Fuxing Li, Wei Gu

“…Smoking, elevated ferritin and white blood cell levels, decreased fibrinogen and platelet levels are more susceptible to developing AP.…”
Get full text

An Enhanced Active Disturbance Rejection Control Scheme for DC Voltage Regulation in Photovoltaic Grid-Connected Four-Leg Inverter Using a Sliding Mode Observer by Chebabhi Ali, Defdaf Mabrouk, Syphax Ihammouchen, Nicu Bizon, Benbouhenni Habib, Kessal Abdelhalim, Rekioua Toufik, Benkhoris Mohamed Fouad

“…The results demonstrate robust performance under parameter uncertainties and disturbances, including variations in irradiance, PV cell temperature, DC bus capacitor value, and grid voltage sags.…”
Get full text

Investigation of IL-17A Serum Levels in Patients with Nonmelanoma Skin Cancer by Mehdi Ghahartars, Fatemeh Sedaghat, Elham Khajavi, Amir Ali Nejat, Mahyar Malekzadeh, Abbas Ghaderi, Mohammad Javad Fattahi

“…This cross-sectional study was performed on 60 patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) as well as 57 age-sex matched healthy individuals as control group. …”
Get full text

Oncolytic Viruses and Immunotherapy for the Treatment of Uveal Melanoma and Retinoblastoma: The Current Landscape and Novel Advances by Merve Kulbay, Nicolas Tuli, Massimo Mazza, Armaan Jaffer, Sarinee Juntipwong, Emily Marcotte, Stuti Misty Tanya, Anne Xuan-Lan Nguyen, Miguel N. Burnier, Hakan Demirci

“…These anti-cancer treatment options provide numerous advantages such as selective cancer cell death and the promotion of an anti-tumor immune response, and they prove useful in preventing vision impairment due to macular and/or optic disc involvement. …”
Get full text

Robust ferromagnetism in wafer-scale Fe3GaTe2 above room-temperature by Shuxiang Wu, Zhihao He, Minghui Gu, Lizhu Ren, Jibin Li, Bo Deng, Di Wang, Xinhao Guo, Wanjiong Li, Mingyi Chen, Yijun Chen, Meng Meng, Quanlin Ye, Bing Shen, Xinman Chen, Jiandong Guo, Guozhong Xing, Iam Keong Sou, Shuwei Li

“…The epitaxial Fe3GaTe2 films exhibit robust ferromagnetism, exemplified by high Curie temperature (T C  = 420 K) and large perpendicular magnetic anisotropy (PMA) constant K U = 6.7 × 105 J/m3 at 300 K for nine-unit-cell film. Notably, the ferromagnetic order is preserved even in the one-unit-cell film with T C reaching 345 K, benefiting from the strong PMA (K U = 1.8×105 J/m3 at 300 K). …”
Get full text

A dataset on environmental DNA, bacterio-, phyto- and zooplankton from an emerging periglacial lagoon in Svalbard, ArcticMendeley DataMendeley Data by Sergej Olenin, Dzmitry Lukashanets, Anastasija Zaiko, Aurelija Samuilovienė, Irina Olenina, Evelina Grinienė, Tobia Politi, Aleksej Šaškov, Greta Kilmonaitė, Andrius Šiaulys

“…The dataset contains the results of bacterioplankton (total cell concentration and carbon biomass), phytoplankton (taxonomic composition, cell size for selected taxa, abundance, biomass and carbon biomass), zooplankton (taxonomic composition, abundance), and environmental DNA (eDNA) metabarcoding. …”
Get full text

The Maternal Cytokine and Chemokine Profile of Naturally Conceived Gestations Is Mainly Preserved during In Vitro Fertilization and Egg Donation Pregnancies by Alicia Martínez-Varea, Begoña Pellicer, Vicente Serra, David Hervás-Marín, Alicia Martínez-Romero, José Bellver, Alfredo Perales-Marín, Antonio Pellicer

“…The main outcome measures were, firstly, to follow up plasma levels of interleukin (IL) 1beta, IL2, IL4, IL5, IL6, IL8, IL10, IL17, interferon gamma, tumor necrosis factor-alpha (TNFα), transforming growth factor-beta (TGFβ), regulated upon activation normal T-cell expressed and secreted (RANTES), stromal cell-derived factor 1 alpha (SDF1α), and decidual granulocyte-macrophage colony-stimulating factor (GM-CSF) during the three trimesters of pregnancy during the three trimesters of pregnancy; secondly, to evaluate if the cytokine and chemokine pattern of ED pregnant women differs from that of those with autologous oocytes and, thirdly, to assess if women with preeclampsia show different cytokine and chemokine profile throughout pregnancy versus women with uneventful pregnancies. …”
Get full text

Deletions of N33, STK11 and TP53 Are Involved in the Development of Lymph Node Metastasis in Larynx and Pharynx Carcinomas by Marta Alonso Guervós, César Álvarez Marcos, Mario Hermsen, Andrés Sampedro Nuño, Carlos Suárez, José Luis Llorente

“…Conclusion: We propose that these 3 genes might play a role in the development of metastasis in larynx and pharynx squamous cell carcinomas.…”
Get full text

Concurrent Viewing of H&E and Multiplex Immunohistochemistry in Clinical Specimens by Larry E. Morrison, Tania M. Larrinaga, Brian D. Kelly, Mark R. Lefever, Rachel C. Beck, Daniel R. Bauer

“…<b>Results:</b> Application is made to several clinically relevant specimens, including breast cancer (HER2, ER, and PR), prostate cancer (PSMA, P504S, basal cell, and CD8), Hodgkin’s lymphoma (CD15 and CD30), and melanoma (LAG3). …”
Get full text

Developmental changes of skin quality from breast, back, and thigh of Pekin ducks from 1 to 6 weeks of age by Hao Li, Wenxuan Zheng, Shuo Xin, Ye Hui, Yijun Zhu, Xi Lin, Huaqi Zhang, Yongwen Zhu

“…The skin quality was increased in a quadratic manner, which was associated with the changes in mRNA expression of target genes related to cell proliferation and collagen synthesis.…”
Get full text

Data-driven exploration of weak coordination microenvironment in solid-state electrolyte for safe and energy-dense batteries by Zhoujie Lao, Kehao Tao, Xiao Xiao, Haotian Qu, Xinru Wu, Zhiyuan Han, Runhua Gao, Jian Wang, Xian Wu, An Chen, Lei Shi, Chengshuai Chang, Yanze Song, Xiangyu Wang, Jinjin Li, Yanfei Zhu, Guangmin Zhou

“…The assembled 0.6 Ah Li | |SPAN pouch cell delivers an areal discharge capacity of 3.8 mAh cm−2 at the second cycle with a solid electrolyte areal mass loading of 18.6 mg cm−2 (mass-to-capacity ratio of 4.9).…”
Get full text

Here and there: the double-side transgene localization by P. A. Salnikov, A. A. Khabarova, G. S. Koksharova, R. V. Mungalov, P. S. Belokopytova, I. E. Pristyazhnuk, A. R. Nurislamov, P. Somatich, M. M. Gridina, V. S. Fishman

“…This can be useful for precise insertion mapping and for screening approaches in the field of chromosome engineering, where chromosomal recombination events between transgenes occur in a cell population. To demonstrate the method’s feasibility, we applied it for mapping SB transposon integration in the human HAP1 cell line. …”
Get full text

Exposure to major coronary heart disease events reduces lung cancer risk: a mendelian randomization study based on a European population by Dongming He, Hongting Lu, Xinhuai Ou, Tiaozhan Zheng, Zhiwen Zheng, Zhanyu Xu, Xiaohong Duan, Shikang Li

“…Results The MR analysis, utilizing FinnGen's MCHDE as the exposure factor, revealed a significant reduction in the incidence of non-small cell lung cancer (NSCLC) [odds ratio (OR) 0.893, 95% confidence interval (CI) 0.800–0.998] and small cell lung cancer (SCLC) [OR 0.684, 95% CI 0.500–0.936], highlighting the protective effect of MCHDE against these cancer subtypes. …”
Get full text

Pharmacological Effects of Antioxidant Mycosporine-Glycine in Alleviating Ultraviolet B-Induced Skin Photodamage: Insights from Metabolomic and Transcriptomic Analyses by Kai Wang, Ling Qin, Huan Lin, Mengke Yao, Junhan Cao, Qing Zhang, Changfeng Qu, Yingying He, Jinlai Miao, Ming Liu

“…At the end of the experiment, UVB exposure caused erythema, wrinkling, collagen degradation, and mast cell infiltration in mouse dorsal skin. M-Gly treatment improved skin appearance and reduced mast cell numbers, while also elevating antioxidant levels, including superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH). …”
Get full text

Effects of sodium alginate and calcium on quality attributes of Shepherd’s purse under ultrasound impregnation during blanching processing by Qihui Wu, Zhongyuan Zhang, Yihong Bao, Dajing Li, Xin Wen, Lei Feng, Meimei Nie, Zhuqing Dai, Yayuan Xu

“…Microstructure analysis revealed no significant difference in the internal cell space after Al + Ca + US15 treatment, and the cell morphology remained normal. …”
Get full text

Novel Indices of Glucose Homeostasis Derived from Principal Component Analysis: Application for Metabolic Assessment in Pregnancy by Tina Stopp, Michael Feichtinger, Ingo Rosicky, Gülen Yerlikaya-Schatten, Johannes Ott, Hans Christian Egarter, Christian Schatten, Wolfgang Eppel, Peter Husslein, Martina Mittlböck, Andrea Tura, Christian S. Göbl

“…This study is aimed at assessing the association of previously developed indices of glucose homeostasis derived from principal component analysis (PCA) with parameters of insulin action, secretion, and beta cell function during pregnancy. Methods. In this prospective longitudinal study, an oral glucose tolerance test was performed in sixty-seven pregnant women at two prepartum (12+0 to 22+6 and 24+0 to 28+6) and one postpartum (2 to 11 months) visits. …”
Get full text

Comprehensive bioinformatic profiling of matrix metalloproteinases and their inhibitors: Expression and interaction patterns in head and neck cancer toward predictive biomarkers an... by Rishaba Byju, Sredha Sunil, Sabari Sadhasivan, Rajesh Parsanathan

“…Overexpression of MMPs facilitates tumour progression by promoting ECM turnover, angiogenesis, and cell migration. Head and neck squamous cell carcinoma (HNSCC) exhibits significant upregulation of multiple MMPs and TIMPs, correlating with poor prognosis, using bioinformatics tools to analyse the expression profiles and prognostic significance of MMPs and TIMPs in HNSCC. …”
Get full text

The effect of physical cues on platelet storage lesion by Lihan Cheng, Lu Wang, Shichun Wang, Qi Liu, Ronghua Diao, Chunyan Yao

“…Agitation maintains more cell numbers, better cell morphology, and lower metabolism rate in platelets, and keeps the low activation state of platelets throughout the storage period. …”
Get full text

Optimizing corrosion resistance of the Mg–4Zn-0.5Y-0.5Nd alloy by regulation of secondary phase and grain structure by C.C. Zhao, W.T. Ouyang, M. Wen, C. Yang, D.K. Xu, Y.F. Zheng, T.F. Xi, L.Y. Sheng

“…The results show that the T4 treatment coarsens the equiaxed grains and transforms the secondary phase into thin cell skeleton structure with a slight decrease in area fraction. …”
Get full text