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24541
Docking Studies, Synthesis, Characterization and Evaluation of Their Antioxidant and Cytotoxic Activities of Some Novel Isoxazole-Substituted 9-Anilinoacridine Derivatives
Published 2012-01-01“…The cytotoxic activity of the compounds was also studied in HEp-2 cell line. The docking studies of the synthesized compounds were performed towards the key nucleoside dsDNA by using AutoDock vina 4.0 programme. …”
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24542
Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation
Published 2012-01-01“…Studies in a multitude of models including cell culture, animal and clinical studies demonstrate that citrus-derived flavonoids have therapeutic potential to attenuate dyslipidemia, correct hyperinsulinemia and hyperglycemia, and reduce atherosclerosis. …”
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24543
Behavior of Functionally Graded Porous Plate in Bending with Smoothed Element
Published 2024-12-01“…The bending analysis of functionally graded porous (FGP) plates using a four-node quadrilateral element connected to the C0-type of Reddy's third-order shear deformation theory and cell-based smoothed strains is presented in this paper. …”
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24544
Aberrant Hepatic Methionine Metabolism and Gene Methylation in the Pathogenesis and Treatment of Alcoholic Steatohepatitis
Published 2012-01-01“…The present paper describes the effects of ethanol on the hepatic methionine cycle, followed by evidence for the central role of reduced SAM in the pathogenesis of ASH according to clinical data and experiments in ethanol-fed animals and in cell models. The efficacy of supplemental SAM in the prevention of ASH in animal models and in the clinical treatment of ASH will be discussed.…”
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24545
Time Delay In Necrotic Core Formation
Published 2005-07-01“…We introduce time delay in a cell proliferationprocess. In the case studied in this paper, the model reduces to one ordinaryfunctional-differential equation of the form that depends on the existence ofnecrotic core. …”
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24546
Synthesis of CF<sub>3</sub>-Indazoles via Rh(III)-Catalyzed C-H [4+1] Annulation of Azobenzenes with CF<sub>3</sub>-Imidoyl Sulfoxonium Ylides
Published 2025-01-01“…Moreover, the antitumor activities of selected CF<sub>3</sub>-indazoles against human cancer cell lines were also studied, and the results indicated that several compounds displayed considerable antiproliferative activities.…”
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24547
Cellulose Elementary Fibrils as Deagglomerated Binder for High-Mass-Loading Lithium Battery Electrodes
Published 2025-01-01“…The CEF-based overlithiated layered oxide cathode exhibits a high areal-mass-loading (50 mg cm–2) and a high specific energy density (445.4 Wh kg–1) of a cell.…”
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24548
GPCRs in hypothalamic neurons and their roles in controlling food intake and metabolism
Published 2025-02-01“…This review provides an overview of classical loss and gain-of-function studies on GPCRs related to feeding and metabolism, with a focus on emerging cell-type-specific investigations. These studies reveal that diverse GPCR-expressing neuronal populations are intricately linked to feeding and energy balance. …”
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24549
Selection of electrodes for the ˝in situ˝ electrical resistivity measurements of molten aluminium
Published 2013-01-01“…The device together with measuring cell for ˝in situ˝ measurement of electrical resistivity was developed using four-probe DC technique.…”
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24550
Elaboração de um índice espacial de segurança: estudo de caso da bacia hidrográfica do córrego Água Espraiada – São Paulo/SP
Published 2021-03-01“…This text presents an analysis of the levels of occurrence of vehicles and cell phones thefts in the hydrographic basin area of the córrego Água Espraiada(SP). …”
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24551
Multicriteria Reconfiguration of Distribution Network with Distributed Generation
Published 2012-01-01“…Efficient heuristic and multicriteria methods are used to solve the problem including advanced ant colony algorithm for minimum loss reconfiguration of distribution network, the sorting-out algorithm of cell formation for island performing in postemergency network, and the successive concessions method for multicriteria decision making. …”
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24552
Mapping subcellular RNA localization with proximity labeling
Published 2024-08-01“…Dissecting the spatiotemporal regulation of the transcriptome is key to understanding cell function and fate. However, it remains challenging to effectively enrich and catalogue RNAs from various subcellular structures using traditional approaches. …”
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24553
Systemic Treatment of Vitreous Inflammation
Published 2012-01-01“…The classes of drugs are ever expanding and include corticosteroids, antimetabolites, alkylating agents, T-cell and calcineurin agents, biologic agents, and interferons. …”
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24554
Misplacement of Tracheostomy Tube in the Right Main Bronchus: a Rare Complication
Published 2020-01-01“…A 38-year-old woman known case of metastatic squamous cell carcinoma of the cervical esophagus due to increasing dyspnea and stridor attributed to the pressure effect of the primary mass was scheduled for tracheostomy, which ended up in the right main bronchus. …”
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24555
The Antiapoptotic RBM5/LUCA-15/H37 Gene and Its Role in Apoptosis and Human Cancer: Research Update
Published 2006-01-01“…This review highlights recent evidence that further implicates the LUCA-15 locus in the control of apoptosis and cell proliferation, and focuses on the observations that confirm the tumour-suppressor activity of this gene.…”
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24556
Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy
Published 2005-01-01“…The recurrence, manifested as brain abscesses in the central nervous system, was an uncommon form of MAC disease usually reported postmortem. An increased CD4 cell count, localized and suppurative infection, and the absence of systemic evidence of infection were consistent with a late immune reconstitution syndrome. …”
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24557
Ovarian Non-Hodgkin Lymphoma Revealed by Bone Metastasis: A Rare Pediatric Case
Published 2021-01-01“…The tumor was classified as a diffuse large B-cell lymphoma. The patient has been treated according to the LMB French protocol with good outcome after two years. …”
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24558
Corneal Bee Sting Controlled with Early Surgical Intervention and Systemic High-Dose Steroid Therapy
Published 2014-01-01“…Examinations revealed severe corneal swelling with stinger stuck in deep stroma and endothelial cell loss. She was treated with early surgery including stinger removal and anterior chamber irrigation combined with systemic high-dose steroid therapy. …”
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24559
CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL
Published 2011-01-01“…We report a girl with a history of Ph(−) pre-B-ALL and three years of disease-free survival admitting to our hospital for regular end of treatment checkup with an increased white blood cell count which in follow-up studies and molecular detection of BCR-ABL (p210) fusions gene had been diagnosed as a Ph(+) typical CML. …”
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24560
Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease
Published 2015-01-01“…Chronic graft-versus-host disease (cGVHD) is one of the most important causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). Occurring in 30% to 70% of patients, cGVHD has a median time to onset of 4 to 6 months and most cases present within 2 years after aHSCT. …”
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