Chronic osteomyelitis with pathological fracture induced by Mycoplasma hominis infection: a case report and review of the literature by Ling-Na Zhu, Wen-Bin Shen, Xiao-Yan Zou, Jiang-Cheng Zuo, Ning Xiao

“…Despite a history of bone tuberculosis, the infection was identified as Mycoplasma hominis through culture and mass spectrometry, highlighting the diagnostic challenges due to the organism’s lack of a cell wall. This case underscores the necessity for advanced diagnostic methods and awareness of Mycoplasma hominis in non-urogenital infections.…”
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Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction by Joselle Cook, Steven Song, Anthony Ventimiglia, Carol Luhrs

“…Extramedullary plasmacytomas (EMPs) are defined by the presence of clonal plasma cell proliferation outside of the bone marrow, portending an overall poor prognosis. …”
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Molecular Mechanisms Underlying Activity-Dependent GABAergic Synapse Development and Plasticity and Its Implications for Neurodevelopmental Disorders by Bidisha Chattopadhyaya

“…Emphasizing the molecular mechanisms of GABAergic synapse formation, in particular basket cell perisomatic synapses, this paper draws attention to the links between critical period plasticity, GABAergic synapse maturation, and the consequences of its dysfunction on the development of the nervous system.…”
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Chapter 5: Transplant Production by Kent Cushman

“… Vegetable transplants are affected by many factors, but the most important are water, temperature, fertilization, sunlight, cell size, and length of stay in the greenhouse (Fig. 5-1). …”
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Idée esthétique : prise de site by Jean-Louis Déotte

“…L’article avance la notion de prise de site (à distinguer des œuvres in situ), couplée à celles d’idée esthétique et d’analogie, pour penser un rapport à l’œuvre qui ne soit pas soumis aux valeurs de nouveauté.…”
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The Neosartorya (Aspergillus) fischeri antifungal protein NFAP2 has low potential to trigger resistance development in Candida albicans in vitro by Gábor Bende, Nóra Zsindely, Krisztián Laczi, Zsolt Kristóffy, Csaba Papp, Attila Farkas, Liliána Tóth, Szabolcs Sáringer, László Bodai, Gábor Rákhely, Florentine Marx, László Galgóczy

“…The development of tolerance to NFAP2 decreased tolerance to cell wall, heat, and UV stresses. The development of FLC resistance increased tolerance to cell wall stress and decreased tolerance to heat and UV stresses. …”
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Tannin alleviated reproductive dysfunction in pregnant ewes infected with Haemonchus contortus by Xin Li, Xin Li, Hai Xiang, Hai Xiang, Rong Liang, Rong Liang, Xinyu Han, Xinyu Han, Rongzhen Zhong, Rongzhen Zhong, Hongyu Liu, Hongyu Liu, Yi Fang, Yi Fang

“…Finally, fetal weights were measured, and fetal ovarian tissue samples were taken for transcriptomic analysis.ResultsThe results showed that tannins increased the levels of gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), estrogen (E2), progesterone (P4), human chorionic gonadotropin (hCG), red blood cell (RBC) counts, packed cell volume (PCV), and mRNA levels of gonadotropic axis receptors in pregnant ewes infected with H. contortus (p < 0.05). …”
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Biological mechanisms of dopamine D2-like receptor agonist therapy in diabetes by Zachary Freyberg, Zachary Freyberg, Ronald A. Codario, Ronald A. Codario

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Quencher-Free Fluorescence Monitoring of G‑Quadruplex Folding by Zachary Parada, Tanner G. Hoog, Katarzyna P. Adamala, Aaron E. Engelhart

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Cortical Circuitry and Synaptic Dysfunctions in Alzheimer’s Disease and Other Dementias by Federico Ranieri, Alberto Benussi, Mariagiovanna Cantone, Florinda Ferreri, Javier Márquez-Ruiz

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Inflammation in Liver Diseases by Dechun Feng, Partha Mukhopadhyay, Ju Qiu, Hua Wang

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Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2 by Shaun Martin, Sarah van Veen, Tine Holemans, Seyma Demirsoy, Chris van den Haute, Veerle Baekelandt, Patrizia Agostinis, Jan Eggermont, Peter Vangheluwe

“…Here, we analyzed stable human SHSY5Y cell lines overexpressing wild-type (WT) or ATP13A2 mutants in which three N-terminal lipid binding sites (LBS1–3) were mutated. …”
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The Multifaceted Roles of Myrrha in the Treatment of Breast Cancer: Potential Therapeutic Targets and Promises by Anwar Shams MD, MSc, PhD, Abdullah Ahmed Alzahrani, Taghreed A Ayash MSc, PhD, Shadi Tamur MD, FRCPC, FAAP, Majed AL-Mourgi MD, FRCS, FCCP, FACS

“…Moreover, the GOBO analysis shows an elevated expression profile of the PTGS2/ESR2/EGFR/JUN/MMP2 genes’ signature in the most aggressive breast cancer subtype (Basal) in breast tumor samples and breast cancer cell lines. Furthermore, the STRING protein interaction network and the KEGG analyses indicate that myrrh exerts therapeutic effects on breast cancer by regulating several biological processes such as cell proliferation, cell migration, apoptosis, and various signaling pathways, including TNF, PI3K-Akt, NF-κB, and MAPK. …”
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Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii by Wang M, Zeng Y, Liu M, Zhang D, Zhao D, Wang J, Liu Y, Zhao W

“…Group F showed no masses or inflammatory cell infiltration. Rats in group G presented with masses without ulceration, only chronic and acute inflammatory cell infiltration in pathological. …”
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Immunogenicity and protective efficacy of a multi-antigenic adenovirus-based vaccine candidate against Mycobacterium tuberculosis by Jin-Seung Yun, Jin-Seung Yun, Eunkyung Shin, Young-Ran Lee, Jung-Ah Lee, Hyeokjin Lee, Jong-Seok Kim, Sung Jae Shin, Sang-Jun Ha, Sang-Won Lee, Dokeun Kim, Jung-Sik Yoo, Hye-Sook Jeong

“…Human adenovirus serotype 5 (Ad5), which induces T-cell response, is a widely used viral vector. In this study, we aimed to evaluate the efficacy of a multi-antigenic recombinant Ad5 vectored vaccine and determine the optimal immunization route for enhanced immune response against Mycobacterium tuberculosis.MethodsWe constructed a multi-antigenic recombinant Ad5 vectored vaccine expressing four antigens (Ag85B-ESAT6-MPT64-Rv2660c) of M. tuberculosis (rAd-TB4), immunized with rAd-TB4 (5 × 107 infectious virus units/mouse) twice at an interval of 4 weeks starting at 10 weeks after BCG priming, and evaluated its boosting efficacy in a BCG-primed mouse model, and determined the optimal immunization route.ResultsCompared with the BCG-only (2 × 105 colony forming units/mouse), subcutaneous injection of rAd-TB4 (1 × 107 infectious virus units/mL; two doses) elicited a T-cell response and cytokine production in lung lymphocytes and splenocytes. rAd-TB4 immunization significantly reduced bacterial loads and inflamed lung areas compared to BCG immunization (p < 0.01) and protected against the H37Rv challenge performed at 17 weeks of BCG priming. …”
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m6A Reader PRRC2A Promotes Colorectal Cancer Progression via CK1ε‐Mediated Activation of WNT and YAP Signaling Pathways by Xi Wu, Shiyang Wang, Yuwei Pan, Mengzhen Li, Manyu Song, Hanfu Zhang, Min Deng, Xu Yang, Jiuzhi Xu, Shuo Zhang, Jinhua Zhang, Fengchao Wang, Maksim V. Plikus, Cong Lv, Lu Yu, Zhengquan Yu

“…In this work, a recently identified m6A‐modified RNA reader protein Proline‐rich Coiled‐coil 2a (PRRC2A) is markedly upregulated in CRC, and intestinal epithelium‐specific deletion of Prrc2a significantly suppressed tumor cell growth, stemness, and migratory capacity, while its overexpression promoted these behaviors. …”
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Two Unrelated Iranian Patients with Adenosine Deaminase 2 Deficiency: A Case Report and Review of Treatment by Parvaneh Karimzade, Aziz Eghbali, Mohammad Keramatipour, Reza Shiari, Zahra Golchehre, Mahdieh Taghizadeh, Mazdak Fallahi, Shahrzad Fallah, Nasrin Khakbazan Fard, Narges Eslami, Narges Bazgir, Mahnaz Jamee, Zahra Chavoshzadeh

“…This disorder also includes various hematological manifestations (pure red cell aplasia, pancytopenia, hemolytic anemia, and pancytopenia with bone marrow involvement). …”
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Probiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis by Feray Gençer Bingöl, Duygu Ağagündüz, Ferenc Budán

“…Interest in using probiotic strain-derived cell components and metabolites has also increased as a result of the significant benefits of probiotics. …”
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Assessment of Tools for Marker-Assisted Selection in a Marine Commercial Species: Significant Association between MSTN-1 Gene Polymorphism and Growth Traits by Irma Sánchez-Ramos, Ismael Cross, Jaroslav Mácha, Gonzalo Martínez-Rodríguez, Vladimir Krylov, Laureana Rebordinos

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Evaluating retinal thickness classification in children: A comparison between pediatric and adult optical coherence tomography databases. by Tian Siew Pua, Mohd Izzuddin Hairol

“…The overall agreement between the classification of the adult database and pediatric data for pRNFL was ≥90%, with discrepancies in 46 out of 150 eyes (30.67%); for macula, it was above 72%, with discrepancies in 93 out of 153 eyes (60.78%); and for ganglion cell complex and ganglion cell + inner plexiform layer (GCIPL) the agreement was above 84% and 85%, respectively. …”
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