Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein by N. V. Ivanisenko, L. Hillert, V. A. Ivanisenko, I. N. Lavrik

“…Activation of CD95 leads to the induction of the cell death programme, apoptosis, via formation of the death-inducing signaling complex (DISC). …”
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Expression of a Splice Variant of CYP26B1 in Betel Quid-Related Oral Cancer by Ping-Ho Chen, Ka-Wo Lee, Cheng-Chieh Hsu, Jeff Yi-Fu Chen, Yan-Hsiung Wang, Ker-Kong Chen, Hui-Min David Wang, Hurng-Wern Huang, Bin Huang

“…Cytotoxicity assays were used to measure the effects of arecoline on cell viability in a dose-dependent manner. In vitro and in vivo studies were conducted to evaluate the expression of the CYP26B1 splice variant. …”
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Genome-wide identification of the wall-associated kinase gene family and their expression patterns under various abiotic stresses in soybean (Glycine max (L.) Merr) by Xiangnan Li, Sifei Qi, Lingzhi Meng, Peisen Su, Yongwang Sun, Nan Li, Dan Wang, Yinglun Fan, Yong Song

“…The wall-associated kinase (WAK) gene family encodes functional cell wall-related proteins. These genes are widely presented in plants and serve as the receptors of plant cell membranes, which perceive the external environment changes and activate signaling pathways to participate in plant growth, development, defense, and stress response. …”
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Probiotic Potential of Lactobacillus Strains with Antifungal Activity Isolated from Animal Manure by Soundharrajan Ilavenil, Hyung Soo Park, Mayakrishnan Vijayakumar, Mariadhas Valan Arasu, Da Hye Kim, Sivanesan Ravikumar, Ki Choon Choi

“…Among the thirty LAB strains, four strains, namely, KCC-25, KCC-26, KCC-27, and KCC-28, showed good cell growth and antifungal activity and were selected for further characterization. …”
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Thermosensitive injectable in situ forming hydrogel incorporating anti-oxidative stress and anti-inflammatory nanoparticles for vital pulp therapy of pulpitis by Lixin Zhang, Xianling Ning, Jingyi Cui, Yanqiang Zhao, Fei Xie, Ningxin Zhu, Dan Wang, Man Qin, Zhiqiang Lin, Yuanyuan Wang

“…As a direct pulp capping material, PBNPs@PPP suppressed inflammation progression in pulpitis in rats while also reducing cell necrosis and inflammatory cell infiltration in pulp tissue. …”
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Advances in Microengineered Platforms for Skin Research by Sireesh Kumar Teertam, Vijayasaradhi Setaluri, Jose M. Ayuso

“…Researchers have used microfluidic platforms for a variety of applications in skin research, including epidermal–dermal cellular crosstalk, cell migration, mechanobiology, microbiome–immune response interactions, vascular biology, and wound healing. …”
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Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury by Lisa Debler, Annette Palmer, Sonja Braumüller, Bettina Klohs, Tom Eirik Mollnes, Karlheinz Holzmann, Markus Huber-Lang, Rebecca Halbgebauer

“…After additional HS in PT mice, the gene expression of pathways related to the innate immunity, such as IL-6 production, neutrophil chemotaxis, cell adhesion, and toll-like receptor signaling was upregulated, whereas pathways of the adaptive immune system, such as B- and T-cell activation as well as the MHC class II protein complex, were downregulated. …”
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Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation by Yunxiang Lv, Mengyuan Dai, Muzi Wang, Fangfang Chen, Rongyu Liu

“…We found that rGal-1 inhibited pulmonary inflammatory cell recruitment, mucus secretion, bronchoalveolar lavage fluid (BALF) inflammatory cell infiltration, and cytokine production. …”
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In Vitro Assessment of Anthelmintic Activities of Rauwolfia vomitoria (Apocynaceae) Stem Bark and Roots against Parasitic Stages of Schistosoma mansoni and Cytotoxic Study by Emmanuel Mouafo Tekwu, Kwabena Mante Bosompem, William Kofi Anyan, Regina Appiah-Opong, Kofi Baffour-Awuah Owusu, Mabel Deladem Tettey, Felicia Amanfo Kissi, Alfred Ampomah Appiah, Veronique Penlap Beng, Alexander Kwadwo Nyarko

“…The cytotoxic effects against HepG2 and Chang liver cell assessed using MTT assay method indicated that both plant extracts which were inhibitory to the proliferation of cell lines with IC50 > 20 μg/mL appear to be safe. …”
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PPARG/SPP1/CD44 signaling pathway in alveolar macrophages: Mechanisms of lipid dysregulation and therapeutic targets in idiopathic pulmonary fibrosis by Ganggang Li, Yuwei Zhang, Huanyu Jiang, Xuanyu Wu, Yanwei Hao, Yuchen Su, Yutong Zou, Wenjia Xian, Fei Wang, Quanyu Du

“…To address this, we analyzed 12 bulk RNA-seq and 2 single-cell RNA-seq datasets from the GEO database using machine learning approaches. …”
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Role of the epithelial layer in the generation of superoxide anion by the guinea-pig isolated trachea by G. Sadeghi-Hashjin, P. A. J. Henricks, G. Folkerts, T. Muis, J. Garssen, F. P. Nijkamp

“…However, isolated epithelial cell suspensions did not generate chemiluminescence. …”
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In-situ synthesize of Ag NPs/SiO2 nanocomposite by gamma ray and its application as catalyst in decolorization of dyes by M. Bagherzadeh, M.H. Choopan Dastjerdi, J. Mokhtari, F. Abadian-Naeini, M. Mohsennia

“…To accomplish this, a radiation cell was designed and manufactured close to the reactor's core. …”
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miRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes by Lucien Marchand, Audrey Jalabert, Emmanuelle Meugnier, Kathleen Van den Hende, Nicole Fabien, Marc Nicolino, Anne-Marie Madec, Charles Thivolet, Sophie Rome

“…As miR-375 is highly expressed in the endocrine pancreas, we postulated that its circulating level might reflect beta cell alterations and might be altered in the blood of T1D patients recently diagnosed. …”
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Retrotrans-genomics identifies aberrant THE1B endogenous retrovirus fusion transcripts in the pathogenesis of sarcoidosis by Shunsuke Funaguma, Aritoshi Iida, Yoshihiko Saito, Jantima Tanboon, Francia Victoria De Los Reyes, Kyuto Sonehara, Yu-ichi Goto, Yukinori Okada, Shinichiro Hayashi, Ichizo Nishino

“…The expression profiles of THE1B fusion transcripts in tuberculosis (TB) significantly differed from SM in single-cell RNA-seq data, suggesting that the differences between TB’s caseous granulomas and sarcoidosis’s non-caseous granulomas might be linked to disparate expression patterns of THE1B fusion transcripts. …”
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YafN-YafO toxin-antitoxin system contributes to stress resistance and virulence of avian pathogenic Escherichia coli by Qiubo Chen, Yunyan Sun, Qianlong Xing, Zhengliang Li, Song Gao, Qingqing Gao

“…The deletion of yafNO resulted in a significant reduction in persister cell formation under antibiotic and environmental stress (P < 0.01). …”
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Temporal Changes in Gene Expression Profile during Mature Adipocyte Dedifferentiation by Julie Anne Côté, Frédéric Guénard, Julie Lessard, Marc Lapointe, Simon Biron, Marie-Claude Vohl, André Tchernof

“…Expression of several genes coding for proteins implicated in cellular proliferation and growth or cell cycle increased significantly from day 7 to day 12 (WNT5A, KITLG, and FGF5). …”
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Comparison of Femtosecond Laser-Assisted Cataract Surgery and Conventional Phacoemulsification in Shallow Anterior Chambers and Glaucoma by Zhou Zhou, Li Li, Siming Zeng, Wenjing He, Min Li

“…The outcome measures included pre- and postoperative uncorrected and corrected distance visual acuity (UDVA and CDVA), intraocular pressure (IOP), endothelial cell density (ECD), endothelial cell loss (ECL), and object scatter index (OSI). …”
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Physiological and transcriptome analysis of sex-specific responses to cadmium stress in poplars by Meihua Liu, Sumei Wu, Yigang Song, Mengjiao Shi, Lita Yi

“…Over 70 % of the Cd was distributed in the cell wall fraction of roots, stems, and leaves, with the majority accumulating in the roots. …”
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A distinct metabolomic pattern revealed intestinal microenvironment factor-mediated food allergy in a BALB/c mouse model by Qiang Xie, Chenglong Liu, Wenhui Fu, Chen Chen, Dan Luo, Shimin Gu, Wentong Xue

“…Our results showed that gluten sensitization induced severe allergic responses in BALB/c mice, characterized by exacerbated clinical allergic and diarrheal symptoms, increased histamine, elevated gluten-specific immunoglobulin (Ig)E and IgG2a levels, and increased mast cell degranulation. In response to GA, T-cell balance was disrupted, with aberrant production of interleukin (IL)-4, interferon (IFN)-γ, IL-10, and IL-2 in the spleen. …”
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Design of precursors and pH factors for enhancing the performance of nickel-based catalysts for anion exchange membrane water electrolysis by Eon-ju Park, Chiho Kim, Jooyoung Lee, Shin-Woo Myeong, Hoseok Lee, Sungjun Heo, Song Jin, Minjeong Park, Oi Lun Li, Sung Mook Choi

“…In addition, to verify universality of the N-NiO study and to assess the water electrolysis performance, we synthesized a binary compound, nickel–cobalt oxide (NCO), by incorporating Co, and evaluated its electrochemical performance in an AEMWE single-cell system. The nitrate-based NCO-based single-cell achieved a high current density of 1.38 A/cm2 at 1.8 Vcell in 1 M KOH at 50 °C, with a low degradation rate of 23 mV/kh at 1 A/cm2 for 300 h. …”
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