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24021
Sialidase NEU3 dynamically associates to different membrane domains specifically modifying their ganglioside pattern and triggering Akt phosphorylation.
Published 2014-01-01“…Moreover, the enzyme is present both at the cell surface and in endosomal structures and cofractionates with caveolin. …”
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24022
Novel approaches in myelofibrosis
Published 2024-12-01“…Currently, the management of MF patients is tailored according to risk scores, with higher‐risk (intermediate‐2 and high‐risk) patients being assessed for allogeneic stem cell transplantation, which remains the only potentially curative treatment option. …”
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24023
A Comprehensive Methodological Review of Major Developments in Bioinformatics Pipelines for Transcriptomic Data Analysis
Published 2025-01-01“…RNA sequencing (RNA-Seq) is a common method used to study the complete set of RNA molecules (the transcriptome) in different cell types, genetic backgrounds, and environments. …”
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24024
Synthesis, characterization, antimicrobial, antioxidant, and anti-cancer activity of new hybrid structures based on benzimidazole and thiadiazole
Published 2025-01-01“…The compound 5g stands out in the series in that it is not toxic on the healthy cell line and has promising antimicrobial activity.…”
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24025
Decolorization and Bioelectricity Generation from Palm Oil Mill Effluent by a Photosynthetic Bacterial Consortium
Published 2025-01-01“…Following treatment, the cell pellet was recovered and analyzed for valuable by-products. …”
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24026
Mechanical Properties of Sandwiched Construction with Composite and Hybrid Core Structure
Published 2024-01-01“…It finally integrated both into one hybrid open-cell core filled with foam and employed the same device (WBW-100E) to conduct the three-point bending experiment. …”
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24027
Acute Lymphoblastic Leukemia following Lenalidomide Maintenance for Multiple Myeloma: Two Cases with Unexpected Presentation and Good Prognostic Features
Published 2018-01-01“…Lenalidomide maintenance following autologous stem cell transplant (ASCT) is considered the standard of care for eligible patients with multiple myeloma (MM). …”
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24028
Morphological and molecular genetic diagnosis of lung cancer: methods and problems
Published 2020-09-01“…An important condition is obtaining a sufficient number of cell or tissue substrate, can reliably establish the malignant process, to determine the histologic tumor type (whether it’s adenocarcinoma or squamous cell carcinoma), carry out the immunohistochemical and molecular genetic study to determine indications for the purpose of targeted, immunotherapy and the selection of chemotherapy regimen. …”
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24029
Targeted Regulation Of Cgrp Gene Expression
Published 2001-01-01“…These studies suggest that modulation of MAP kinase control of the cell-specific CGRP gene enhancer may be a useful therapeutic strategy for neurovascular disorders.…”
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24030
Noncoding RNAs Associated with PPARs in Etiology of MAFLD as a Novel Approach for Therapeutics Targets
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24031
Within-host bayesian joint modeling of longitudinal and time-to-event data of Leishmania infection.
Published 2024-01-01“…In addition to measuring antibody levels produced by the immune system, we adapt data from CD4+ and CD8+ T cell proliferation, and expression of interleukin 10, interferon-gamma, and programmed cell death 1 as inflammatory or regulatory factors mediating the disease process. …”
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24032
Juvenile Myelomonocytic Leukemia in a Child: A Case Report of Palliative Chemotherapy and Literature Review Applied to Limited Resources Centers
Published 2022-01-01“…Initial laboratory workup showed hemoglobin of 6.4 g/dl, white blood cell of 315.62 × 103/μL, and platelet of 17 × 103/μL. …”
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24033
Effects of Trace Metal Profiles Characteristic for Autism on Synapses in Cultured Neurons
Published 2015-01-01“…We analyzed whether an imbalance of any one metal ion alters cell health and synapse numbers. Moreover, we evaluated whether a biometal profile characteristic for ASD patients influences synapse formation, maturation, and composition regarding NMDA receptor subunits and Shank proteins. …”
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24034
Motivations, activités et expériences du tourisme oléicole : Perspectives d’un panel Delphi portugais
Published 2024-07-01“…La tendance à une consommation plus saine et plus authentique contribue à une demande croissante pour des propositions qui valorisent de plus en plus les valeurs et les ressources du monde rural, y compris celles liées à l’oléiculture. Grâce à la méthode Delphi et à la collaboration d’un panel de 12 experts portugais, spécialistes de l’oléotourisme, cette étude vise à identifier la gamme la plus importante possible d’activités, d’expériences et de motivations oléotouristiques. …”
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24035
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24036
Protective Effects of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, against Cisplatin-Induced Nephrotoxicity in Mice
Published 2017-01-01“…Gemigliptin attenuated cisplatin-induced apoptotic cell death, as assessed by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling and Western blot analysis in the kidneys. …”
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24037
Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report
Published 2016-01-01“…Blood exams highlighted the presence of a monoclonal B cell clone. Bone marrow concluded to a B cell lymphoma of the marginal zone. …”
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24038
Seasonal Dynamics of the Bacterial Community in Lake Urmia, a Hypersaline Ecosystem
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24039
Organoid development and applications in gynecological cancers: the new stage of tumor treatment
Published 2025-01-01“…Organoid technology has emerged as a transformative tool in cancer research, offering in vitro models that closely replicate the tumor cell architecture and heterogeneity of primary cancers. …”
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24040
ER Stress and Iron Homeostasis: A New Frontier for the UPR
Published 2011-01-01“…The conformational changes introduced by this mutation impair the HFE association with β2-microglobulin (β2m) and the cell surface expression of the protein: with two major consequences. …”
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